{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T06:24:01Z","timestamp":1773469441515,"version":"3.50.1"},"reference-count":93,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2020,5,11]],"date-time":"2020-05-11T00:00:00Z","timestamp":1589155200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Catalysts"],"abstract":"<jats:p>The development of cross-dehydrogenative coupling in recent years has simplified the synthesis of many materials, as a result of facile C\u2013H activation, which, together with its greater atom economy and environmental friendliness, has made an impact on modern organic chemistry. Indeed, many C\u2013C and C\u2013X (X = N, O, P, S, B, or Si) coupling reactions can now be performed directly between two C\u2013H bonds or a C\u2013H and an X\u2013H bond, simply by adding catalytic amounts of a metal salt to a mixture of the two and an oxidant to accept the two hydrogen atoms released. Chiral organocatalysts or chiral ligands have been joined to promote enantioselective processes, resulting in the development of efficient reaction cascades that provide products in high yields and high levels of asymmetric induction through cooperative catalysis. In recent years, photochemical oxidation and electrochemistry have widened even more the scope of cross-dehydrogenative coupling (CDC). In this review, we summarized the recent literature in this subject, hoping that it will inspire many new synthetic strategies.<\/jats:p>","DOI":"10.3390\/catal10050529","type":"journal-article","created":{"date-parts":[[2020,5,11]],"date-time":"2020-05-11T10:01:18Z","timestamp":1589191278000},"page":"529","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["New Trends in Enantioselective Cross-Dehydrogenative Coupling"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3101-016X","authenticated-orcid":false,"given":"Ana Maria","family":"Faisca Phillips","sequence":"first","affiliation":[{"name":"Centro de Qu\u00edmica Estrutural, Instituto Superior Te\u0301cnico, Universidade de Lisboa, Av. Rovisco Pais, 1049\u2212001 Lisbon, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4836-2409","authenticated-orcid":false,"given":"Maria de F\u00e1tima","family":"C. Guedes da Silva","sequence":"additional","affiliation":[{"name":"Centro de Qu\u00edmica Estrutural, Instituto Superior Te\u0301cnico, Universidade de Lisboa, Av. Rovisco Pais, 1049\u2212001 Lisbon, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8323-888X","authenticated-orcid":false,"given":"Armando J. L.","family":"Pombeiro","sequence":"additional","affiliation":[{"name":"Centro de Qu\u00edmica Estrutural, Instituto Superior Te\u0301cnico, Universidade de Lisboa, Av. Rovisco Pais, 1049\u2212001 Lisbon, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2020,5,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"12705","DOI":"10.1021\/acs.joc.9b01704","article-title":"En route to intermolecular cross-dehydrogenative coupling reactions","volume":"84","author":"Huang","year":"2019","journal-title":"J. Org. 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