{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T05:26:00Z","timestamp":1766553960156,"version":"3.48.0"},"reference-count":40,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T00:00:00Z","timestamp":1766361600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001871","name":"MCTES","doi-asserted-by":"publisher","award":["SFRH\/BD\/150790\/2020"],"award-info":[{"award-number":["SFRH\/BD\/150790\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"crossref"}]},{"name":"FCT\/MCTES\u2014CEEC Individual Program Contract"},{"name":"PT national funds"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chemosensors"],"abstract":"<jats:p>In this work, a potentiometric sensor for the detection of biogenic amines (BAs) in food samples was developed and characterised. The sensor employs a home-fabricated electrode incorporating a cucurbit[6]uril-modified polyvinyl chloride membrane as the sensing element. The working principle, system behaviour, and optimal operational conditions for BA monitoring were systematically investigated. The developed sensor demonstrated excellent analytical performance, showing a linear response in the concentration range of 3.0 \u00d7 10\u22125 to 1.0 \u00d7 10\u22122 mol L\u22121, with a low limit of detection of 2.4 \u00d7 10\u22125 mol L\u22121. Among the tested analytes, the sensor exhibited the highest sensitivity toward tyramine. These results highlight the potential of the proposed cucurbit[6]uril-based potentiometric sensor as an effective and reliable tool for monitoring BAs in complex food matrices, contributing to improved food safety, quality control, and spoilage prevention in the food industry, while also demonstrating its new application as a low-cost, easily constructed platform for rapid tyramine screening in food products.<\/jats:p>","DOI":"10.3390\/chemosensors14010004","type":"journal-article","created":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T11:30:18Z","timestamp":1766489418000},"page":"4","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Potentiometric Determination of Biogenic Amines Using a Cucurbit[6]uril-PVC Sensing Membrane"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4512-7980","authenticated-orcid":false,"given":"Cl\u00e1udio M. R.","family":"Almeida","sequence":"first","affiliation":[{"name":"University of Coimbra, CERES, Department of Chemical Engineering, 3030-790 Coimbra, Portugal"},{"name":"LAQV-REQUIMTE, Departamento de Engenharia Qu\u00edmica, Faculdade de Engenharia, Universidade do Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9650-303X","authenticated-orcid":false,"given":"Joana L. A.","family":"Miranda","sequence":"additional","affiliation":[{"name":"LAQV-REQUIMTE, Departamento de Engenharia Qu\u00edmica, Faculdade de Engenharia, Universidade do Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1500-9211","authenticated-orcid":false,"given":"Manuela M.","family":"Moreira","sequence":"additional","affiliation":[{"name":"LAQV-REQUIMTE, Instituto Superior de Engenharia do Porto, Instituto Polit\u00e9cnico do Porto, Rua Dr. Ant\u00f3nio Bernardino de Almeida 431, 4200-072 Porto, Portugal"}]},{"given":"J\u00falia M. C. S.","family":"Magalh\u00e3es","sequence":"additional","affiliation":[{"name":"LAQV-REQUIMTE, Departamento de Engenharia Qu\u00edmica, Faculdade de Engenharia, Universidade do Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9011-5992","authenticated-orcid":false,"given":"Maria F.","family":"Barroso","sequence":"additional","affiliation":[{"name":"LAQV-REQUIMTE, Instituto Superior de Engenharia do Porto, Instituto Polit\u00e9cnico do Porto, Rua Dr. Ant\u00f3nio Bernardino de Almeida 431, 4200-072 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3336-2449","authenticated-orcid":false,"given":"Luisa","family":"Dur\u00e3es","sequence":"additional","affiliation":[{"name":"University of Coimbra, CERES, Department of Chemical Engineering, 3030-790 Coimbra, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2025,12,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"\u00d6zogul, Y., and \u00d6zogul, F. 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