{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T23:40:41Z","timestamp":1775259641968,"version":"3.50.1"},"reference-count":24,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2024,1,31]],"date-time":"2024-01-31T00:00:00Z","timestamp":1706659200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"European Regional Development Fund (ERDF)","award":["Norte-01-0145-FEDER-000042"],"award-info":[{"award-number":["Norte-01-0145-FEDER-000042"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computers"],"abstract":"<jats:p>Schizophrenia is a mental illness that requires the use of cognitive treatments to decrease symptoms in which the use of medication is less effective. Innovative strategies such as the use of Virtual Reality (VR) are being tested, but there is still a long way into developing solutions as effective as the current conventional forms of treatment. To study more effective forms of developing these systems, an immersive VR game with a tutorial and two levels of difficulty was developed. Tests were performed in twenty-one healthy subjects, showing promising results, indicating VR\u2019s potential as a complementary approach to conventional treatments for schizophrenia. When properly applied, the use of VR could lead to more efficient and accessible treatments, potentially reducing its costs and reaching a broader population.<\/jats:p>","DOI":"10.3390\/computers13020042","type":"journal-article","created":{"date-parts":[[2024,1,31]],"date-time":"2024-01-31T10:44:24Z","timestamp":1706697864000},"page":"42","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Application of Immersive VR Serious Games in the Treatment of Schizophrenia Negative Symptoms"],"prefix":"10.3390","volume":"13","author":[{"given":"Beatriz","family":"Miranda","sequence":"first","affiliation":[{"name":"ADiT-Lab\u2014Applied Digital Transformation Laboratory, Instituto Polit\u00e9cnico de Viana do Castelo, 4900-347 Viana do Castelo, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8188-1804","authenticated-orcid":false,"given":"Paula Alexandra","family":"Rego","sequence":"additional","affiliation":[{"name":"ADiT-Lab\u2014Applied Digital Transformation Laboratory, Instituto Polit\u00e9cnico de Viana do Castelo, 4900-347 Viana do Castelo, Portugal"},{"name":"LIACC\u2014Laborat\u00f3rio de Intelig\u00eancia Artificial e Ci\u00eancia de Computadores, Universidade do Porto, 4050-465 Porto, Portugal"}]},{"given":"Lu\u00eds","family":"Romero","sequence":"additional","affiliation":[{"name":"ADiT-Lab\u2014Applied Digital Transformation Laboratory, Instituto Polit\u00e9cnico de Viana do Castelo, 4900-347 Viana do Castelo, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8371-0347","authenticated-orcid":false,"given":"Pedro Miguel","family":"Moreira","sequence":"additional","affiliation":[{"name":"ADiT-Lab\u2014Applied Digital Transformation Laboratory, Instituto Polit\u00e9cnico de Viana do Castelo, 4900-347 Viana do Castelo, Portugal"},{"name":"LIACC\u2014Laborat\u00f3rio de Intelig\u00eancia Artificial e Ci\u00eancia de Computadores, Universidade do Porto, 4050-465 Porto, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2024,1,31]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"64","DOI":"10.3389\/fpsyt.2016.00064","article-title":"A Serious Game to Improve Cognitive Functions in Schizophrenia: A Pilot Study","volume":"7","author":"Amado","year":"2016","journal-title":"Front. 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