{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:01:05Z","timestamp":1760148065404,"version":"build-2065373602"},"reference-count":59,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2023,3,28]],"date-time":"2023-03-28T00:00:00Z","timestamp":1679961600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"FEDER funds through the COMPETE 2020 Program","award":["LA\/P\/0037\/2020","UIDP\/50025\/2020","UIDB\/50025\/2020","17956"],"award-info":[{"award-number":["LA\/P\/0037\/2020","UIDP\/50025\/2020","UIDB\/50025\/2020","17956"]}]},{"name":"Associate Laboratory Institute of Nanostructures, Nanomodelling and Nanofabrication\u2014i3N","award":["LA\/P\/0037\/2020","UIDP\/50025\/2020","UIDB\/50025\/2020","17956"],"award-info":[{"award-number":["LA\/P\/0037\/2020","UIDP\/50025\/2020","UIDB\/50025\/2020","17956"]}]},{"name":"DENTALBLAST project","award":["LA\/P\/0037\/2020","UIDP\/50025\/2020","UIDB\/50025\/2020","17956"],"award-info":[{"award-number":["LA\/P\/0037\/2020","UIDP\/50025\/2020","UIDB\/50025\/2020","17956"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Crystals"],"abstract":"<jats:p>The use of orthopaedic and dental implants is expanding as a consequence of an ageing population and also due to illness or trauma in younger age groups. The implant must be biocompatible, bioactive and interact favourably with the recipient\u2019s bone, as rapid osseointegration is key to success. In this work, Ti-6Al-4V plates were coated using the CoBlastTM technique, with hydroxyapatite (HAp) and HAp\/BaTiO3 (barium titanate, BT) non-piezoelectric cubic nanopowders (HAp\/cBT) and piezoelectric tetragonal micropowders (HAp\/tBT). The addition of BT, a piezoelectric ceramic, is a strategy to accelerate osseointegration by using surface electric charges as cues for cells. For comparison with commercial coatings, plates were coated with HAp using the plasma spray technique. Using XRD and FTIR, both plasma spray and CoBlastTM coatings showed crystalline HAp and no presence of by-products. However, the XRD of the plasma-sprayed coatings revealed the presence of amorphous HAp. The average surface roughness was close to the coatings\u2019 thickness (\u22485 \u03bcm for CoBlastTM and \u224813 \u03bcm for plasma spray). Cytotoxicity assays proved that the coatings are biocompatible. Therefore, it can be concluded that for HAp-based coatings, CoBlastTM is a viable alternative to plasma spray, with the advantage of facilitating room temperature addition of other ceramics, like piezoelectric BaTiO3.<\/jats:p>","DOI":"10.3390\/cryst13040579","type":"journal-article","created":{"date-parts":[[2023,3,28]],"date-time":"2023-03-28T06:15:15Z","timestamp":1679984115000},"page":"579","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Hydroxyapatite-Barium Titanate Biocoatings Using Room Temperature Coblasting"],"prefix":"10.3390","volume":"13","author":[{"given":"In\u00eas J. G.","family":"Dias","sequence":"first","affiliation":[{"name":"CENIMAT|i3N, Department of Materials Science, School of Science and Technology, NOVA University Lisbon, 2829-516 Caparica, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5707-9157","authenticated-orcid":false,"given":"A. Sofia","family":"P\u00e1dua","sequence":"additional","affiliation":[{"name":"CENIMAT|i3N, Department of Materials Science, School of Science and Technology, NOVA University Lisbon, 2829-516 Caparica, Portugal"},{"name":"CENIMAT|i3N, Department of Physics, School of Science and Technology, NOVA University Lisbon, 2829-516 Caparica, Portugal"}]},{"given":"Eduardo A.","family":"Pires","sequence":"additional","affiliation":[{"name":"Bioceramed, R. Jos\u00e9 Gomes Ferreira n\u00ba1 Arm. D, 2660-360 S\u00e3o Juli\u00e3o do Tojal, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3996-6545","authenticated-orcid":false,"given":"Jo\u00e3o P. M. R.","family":"Borges","sequence":"additional","affiliation":[{"name":"CENIMAT|i3N, Department of Materials Science, School of Science and Technology, NOVA University Lisbon, 2829-516 Caparica, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9959-4272","authenticated-orcid":false,"given":"Jorge C.","family":"Silva","sequence":"additional","affiliation":[{"name":"CENIMAT|i3N, Department of Physics, School of Science and Technology, NOVA University Lisbon, 2829-516 Caparica, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9258-4899","authenticated-orcid":false,"given":"M. Carmo","family":"Lan\u00e7a","sequence":"additional","affiliation":[{"name":"CENIMAT|i3N, Department of Materials Science, School of Science and Technology, NOVA University Lisbon, 2829-516 Caparica, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2023,3,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.mser.2007.12.001","article-title":"Advanced Biomaterials for Skeletal Tissue Regeneration: Instructive and Smart Functions","volume":"59","author":"Mahmood","year":"2008","journal-title":"Mater. Sci. Eng. R Rep."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"95","DOI":"10.3390\/coatings2030095","article-title":"Surface Engineering for Bone Implants: A Trend from Passive to Active Surfaces","volume":"2","author":"Bosco","year":"2012","journal-title":"Coatings"},{"key":"ref_3","unstructured":"LaWell, C. (2023, January 18). Orthopedic Market Projected to Grow 3.4% in 2022. 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