{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:43:36Z","timestamp":1760060616683,"version":"build-2065373602"},"reference-count":40,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T00:00:00Z","timestamp":1757894400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Faculty of Dental Medicine of the University of Lisbon"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dentistry Journal"],"abstract":"<jats:p>Introduction: Type 1 diabetes mellitus (DM1) can influence oral health, increasing susceptibility to various oral manifestations. Objectives: This study aimed to characterise oral health-related quality of life (OHRQoL), reported oral symptoms, and oral health behaviours in paediatric individuals with DM1, and compare them with those without DM1; as well as to identify factors associated with OHRQoL in both groups. Methods: A cross-sectional study was conducted using an online questionnaire completed by caregivers of Portuguese children with or without DM1. The questionnaire collected information on sociodemographic, oral health behaviours, perceived oral health, reported oral manifestations, and OHRQoL using the Early Childhood Oral Health Impact Scale (ECOHIS). Descriptive statistics were calculated, along with chi-square tests and negative binomial regression analyses (\u03b1 = 0.05). Results: The sample included 235 individuals (115 with DM1 and 120 without). No significant differences were observed in overall OHRQoL between the groups, although children with DM1 had slightly higher ECOHIS total scores (4.38 vs. 4.02). Oral health behaviours were comparable in both groups. Children with DM1 reported significantly more xerostomia (p &lt; 0.001). Within the DM1 group, better OHRQoL was significantly related to the following variables: female sex, absence of caries, absence of gingivitis, and no taste changes. In contrast, in the non-DM1 group, OHRQoL was associated with different conditions: the caregiver perception, frequent sugar intake, recurrent aphthous stomatitis, burning mouth sensations, and age. Conclusion: Although OHRQoL levels and oral health behaviours were similar between children with and without DM1, the factors influencing these outcomes varied considerably, emphasising the need for targeted oral health strategies tailored to the specific context of this chronic condition.<\/jats:p>","DOI":"10.3390\/dj13090425","type":"journal-article","created":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T16:27:33Z","timestamp":1757953653000},"page":"425","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Oral Health-Related Quality of Life, Behaviours and Oral Manifestations in a Paediatric Population with Type I Diabetes Mellitus: A Comparative Cross-Sectional Study"],"prefix":"10.3390","volume":"13","author":[{"given":"Patr\u00edcia","family":"Jo\u00e3o","sequence":"first","affiliation":[{"name":"Faculdade de Medicina Dent\u00e1ria, Universidade de Lisboa, Rua Professora Teresa Ambr\u00f3sio, 1600-277 Lisbon, Portugal"}]},{"given":"Ana Coelho","family":"Canta","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina Dent\u00e1ria, Universidade de Lisboa, Rua Professora Teresa Ambr\u00f3sio, 1600-277 Lisbon, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8831-5872","authenticated-orcid":false,"given":"S\u00f3nia","family":"Mendes","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina Dent\u00e1ria, Universidade de Lisboa, Rua Professora Teresa Ambr\u00f3sio, 1600-277 Lisbon, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2025,9,15]]},"reference":[{"doi-asserted-by":"crossref","unstructured":"Triebl, Z., Bencze, B., B\u00e1nyai, D., R\u00f3zsa, N., Hermann, P., and V\u00e9gh, D. (2024). Poor glycemic control impairs oral health in children with type 1 diabetes mellitus\u2014A systematic review and meta-analysis. BMC Oral Health, 24.","key":"ref_1","DOI":"10.1186\/s12903-024-04516-y"},{"doi-asserted-by":"crossref","unstructured":"American Diabetes Association (2014). Diagnosis and classification of diabetes mellitus. Diabetes Care, 37, S81\u2013S90.","key":"ref_2","DOI":"10.2337\/dc14-S081"},{"doi-asserted-by":"crossref","unstructured":"American Diabetes Association Professional Practice Committee (2024). 10. Cardiovascular disease and risk management: Standards of care in diabetes\u20142024. Diabetes Care, 47, S179\u2013S218.","key":"ref_3","DOI":"10.2337\/dc24-S010"},{"doi-asserted-by":"crossref","unstructured":"American Diabetes Association Professional Practice Committee (2024). 11. Chronic kidney disease and risk management: Standards of care in diabetes\u20142024. Diabetes Care, 47, S219\u2013S230.","key":"ref_4","DOI":"10.2337\/dc24-S011"},{"doi-asserted-by":"crossref","unstructured":"American Diabetes Association Professional Practice Committee (2024). 12. Retinopathy, neuropathy, and foot care: Standards of care in diabetes\u20142024. Diabetes Care, 47, S231\u2013S243.","key":"ref_5","DOI":"10.2337\/dc24-S012"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.diabres.2015.03.003","article-title":"Oral health of children with type 1 diabetes mellitus: A systematic review","volume":"108","author":"Ismail","year":"2015","journal-title":"Diabetes Res. Clin. Pract."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1515\/jpem-2018-0335","article-title":"Assessment of dental caries and gingival status among a group of type 1 diabetes mellitus and healthy children of South India\u2014A comparative study","volume":"31","author":"Babu","year":"2018","journal-title":"J. Pediatr. Endocrinol. Metab."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1016\/j.sdentj.2024.03.012","article-title":"Dental health status of children with diabetes in Riyadh, Saudi Arabia","volume":"36","year":"2024","journal-title":"Saudi Dent. J."},{"unstructured":"International Diabetes Federation (2025, May 20). IDF Diabetes Atlas 2025. Available online: https:\/\/diabetesatlas.org\/resources\/idf-diabetes-atlas-2025\/.","key":"ref_9"},{"unstructured":"Sociedade Portuguesa de Endocrinologia, Diabetes e Metabolismo (SPEDM) (2025, May 20). Programa Nacional para a Diabetes: Desafios e Estrat\u00e9gias 2023. Available online: https:\/\/www.spedm.pt\/pt\/noticias-spedm\/programa-nacional-para-a-diabetes-desafios-e-estrategias-2023.","key":"ref_10"},{"doi-asserted-by":"crossref","unstructured":"Mohseni Homagarani, Y., Adlparvar, K., Teimuri, S., Tarrahi, M.J., and Nilchian, F. (2023). The effect of diabetes mellitus on oral health-related quality of life: A systematic review and meta-analysis. Front. Public Health, 11.","key":"ref_11","DOI":"10.3389\/fpubh.2023.1112008"},{"key":"ref_12","first-page":"230","article-title":"Oral health-related quality of life in diabetic patients","volume":"8","author":"Sadeghi","year":"2014","journal-title":"J. Dent. Res. Dent. Clin. Dent. Prospects"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4103\/2231-0762.115700","article-title":"Oral health-related quality of life","volume":"3","author":"Bennadi","year":"2013","journal-title":"J. Int. Soc. Prev. Community Dent."},{"doi-asserted-by":"crossref","unstructured":"Pakkhesal, M., Riyahi, E., Naghavi Alhosseini, A., Amdjadi, P., and Behnampour, N. (2021). Impact of dental caries on oral health-related quality of life among preschool children: Perceptions of parents. BMC Oral Health, 21.","key":"ref_14","DOI":"10.1186\/s12903-021-01396-4"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1007\/s40368-023-00842-x","article-title":"Oral health-related quality of life in celiac Portuguese children: A cross-sectional study","volume":"24","author":"Coelho","year":"2023","journal-title":"Eur. Arch. Paediatr. Dent."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"379626","DOI":"10.1155\/2015\/379626","article-title":"Periodontal diseases and dental caries in children with type 1 diabetes mellitus","volume":"2015","author":"Novotna","year":"2015","journal-title":"Mediat. Inflamm."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s00125-011-2342-y","article-title":"Periodontitis and diabetes: A two-way relationship","volume":"55","author":"Preshaw","year":"2012","journal-title":"Diabetologia"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"5780916","DOI":"10.1155\/2018\/5780916","article-title":"The influence of type 1 diabetes mellitus on dental caries and salivary composition","volume":"2018","author":"Ferizi","year":"2018","journal-title":"Int. J. Dent."},{"key":"ref_19","first-page":"229","article-title":"Diabetes mellitus and related oral manifestations","volume":"1","author":"Pedersen","year":"2004","journal-title":"Oral Biosci. Med."},{"unstructured":"Costa, M.I.B.C. (2014). Qualidade de Vida Relacionada com a Sa\u00fade Oral em Adolescentes. [Ph.D. Thesis, Universidade do Porto].","key":"ref_20"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/1477-7525-5-6","article-title":"Parental perceptions of children\u2019s oral health: The Early Childhood Oral Health Impact Scale (ECOHIS)","volume":"5","author":"Pahel","year":"2007","journal-title":"Health Qual. Life Outcomes"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"39","DOI":"10.15644\/asc58\/1\/4","article-title":"Early Childhood Oral Health Impact Scale: Psychometric evaluation in Portuguese preschoolers","volume":"58","author":"Correia","year":"2024","journal-title":"Acta Stomatol. Croat."},{"doi-asserted-by":"crossref","unstructured":"Halbig, J.M., J\u00f6nsson, B., Gil, E.G., \u00c5str\u00f8m, A.N., Rypdal, V., Frid, P., Augdal, T.A., Fischer, J., Cetrelli, L., and Rygg, M. (2023). Oral health-related quality of life, impaired physical health and orofacial pain in children and adolescents with juvenile idiopathic arthritis\u2014A prospective multicenter cohort study. BMC Oral Health, 23.","key":"ref_23","DOI":"10.1186\/s12903-023-03510-0"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1007\/s40368-022-00741-7","article-title":"Oral health-related quality of life in Portuguese preschool children: A cross-sectional study","volume":"23","author":"Freire","year":"2022","journal-title":"Eur. Arch. Paediatr. Dent."},{"key":"ref_25","first-page":"28","article-title":"Fatores associados \u00e0 qualidade de vida em jovens portugueses de 18 anos","volume":"65","author":"Costa","year":"2024","journal-title":"Rev. Port. Estomatol. Med. Dent. Cir. Maxilofac."},{"key":"ref_26","first-page":"571","article-title":"Impact of dental caries on the quality of life of preschool children and families in Amman, Jordan","volume":"18","author":"Rajab","year":"2020","journal-title":"Oral Health Prev. Dent."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1038\/s41405-021-00061-w","article-title":"Impact of diabetes and periodontal status on life quality","volume":"7","author":"Desai","year":"2021","journal-title":"BDJ Open"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"4033","DOI":"10.1007\/s00784-020-03273-w","article-title":"Oral health status and impact on the oral health-related quality of life of Egyptian children and early adolescents with type 1 diabetes: A case-control study","volume":"24","author":"Elheeny","year":"2020","journal-title":"Clin. Oral Investig."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"200113","DOI":"10.1016\/j.jpedcp.2024.200113","article-title":"How do differences in adolescent and caregiver reports of adolescent adverse childhood experiences relate to adolescent depression?","volume":"13","author":"Ndjatou","year":"2024","journal-title":"J. Pediatr. Clin. Pract."},{"key":"ref_30","first-page":"60","article-title":"Comparison of oral health and quality of life related to it in two- to five-year-old children with type 1 diabetes with healthy children","volume":"34","author":"Salehi","year":"2024","journal-title":"J. Maz. Univ. Med. Sci."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"364","DOI":"10.2337\/ds22-0089","article-title":"A scoping review of the relation between toothbrushing and diabetes knowledge, glycemic control, and oral health outcomes in people with type 2 diabetes","volume":"36","author":"Lipman","year":"2023","journal-title":"Diabetes Spectr."},{"doi-asserted-by":"crossref","unstructured":"Aslan Gonul, B., and Cicek, B. (2024). The Effect of Parents\u2019 Nutrition Literacy on Children\u2019s Oral-Health-Related Quality of Life. Int. J. Environ. Res. Public Health, 21.","key":"ref_32","DOI":"10.3390\/ijerph21091190"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1111\/j.1600-0528.2011.00635.x","article-title":"Impact of clinical status and salivary conditions on xerostomia and oral health-related quality of life of adolescents with type 1 diabetes mellitus","volume":"40","author":"Busato","year":"2012","journal-title":"Community Dent. Oral Epidemiol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.2337\/dc16-1990","article-title":"Factors associated with diabetes-specific health-related quality of life in youth with type 1 diabetes: The Global TEENs Study","volume":"40","author":"Anderson","year":"2017","journal-title":"Diabetes Care"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"e1202","DOI":"10.4317\/jced.58810","article-title":"Oral Health-Related quality of life in Portuguese undergraduate students","volume":"13","author":"Chantre","year":"2021","journal-title":"J. Clin. Exp. Dent."},{"doi-asserted-by":"crossref","unstructured":"Ballo, L., Arheiam, A., and Marhazlinda, J. (2021). Determinants of caries experience and the impact on the OHRQoL of 6-year-old Libyan children: A cross-sectional survey. BMC Oral Health, 21.","key":"ref_36","DOI":"10.1186\/s12903-021-01681-2"},{"doi-asserted-by":"crossref","unstructured":"Alvarez-Azaustre, M.P., Greco, R., and Llena, C. (2021). Oral Health-Related Quality of Life in Adolescents as Measured with the Child-OIDP Questionnaire: A Systematic Review. Int. J. Environ. Res. Public Health, 18.","key":"ref_37","DOI":"10.3390\/ijerph182412995"},{"doi-asserted-by":"crossref","unstructured":"Wang, J., Jin, W., Shi, L., Geng, Y., Zhu, X., and Hu, W. (2022). Health-Related Quality of Life in Children: The Roles of Age, Gender and Interpersonal Trust. Int. J. Environ. Res. Public Health, 19.","key":"ref_38","DOI":"10.3390\/ijerph192215408"},{"doi-asserted-by":"crossref","unstructured":"Alanzi, A., Husain, F., Husain, H., Hanif, A., and Baskaradoss, J.K. (2023). Does the severity of untreated dental caries of preschool children influence the oral health-related quality of life?. BMC Oral Health, 23.","key":"ref_39","DOI":"10.1186\/s12903-023-03274-7"},{"doi-asserted-by":"crossref","unstructured":"Barutta, F., Bellini, S., Durazzo, M., and Gruden, G. (2022). Novel insight into the mechanisms of the bidirectional relationship between diabetes and periodontitis. Biomedicines, 10.","key":"ref_40","DOI":"10.3390\/biomedicines10010178"}],"container-title":["Dentistry Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2304-6767\/13\/9\/425\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T18:45:55Z","timestamp":1760035555000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2304-6767\/13\/9\/425"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,15]]},"references-count":40,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2025,9]]}},"alternative-id":["dj13090425"],"URL":"https:\/\/doi.org\/10.3390\/dj13090425","relation":{},"ISSN":["2304-6767"],"issn-type":[{"type":"electronic","value":"2304-6767"}],"subject":[],"published":{"date-parts":[[2025,9,15]]}}}