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In this work, we address the problem of jointly selecting active panels and associating terminals to outputs of such active panels in a panel-based LIS framework to maximise the minimum signal-to-interference-and-noise ratio (SINR) across all terminals. Due to the nature of the mixed-integer linear programming (MILP) formulation, we propose an alternative approach based on a genetic algorithm (GA) that efficiently explores the solution space through tailored crossover via column swapping and adaptive mutation. We compare the GA\u2019s performance against the CPLEX solver under various configurations and time constraints. The performance results show that the GA provides competitive solutions with reduced computational complexity, showcasing its potential for scalable LIS implementations with complex resource allocation.<\/jats:p>","DOI":"10.3390\/electronics14153107","type":"journal-article","created":{"date-parts":[[2025,8,4]],"date-time":"2025-08-04T15:30:06Z","timestamp":1754321406000},"page":"3107","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Genetic Resource Allocation Algorithm for Panel-Based Large Intelligent Surfaces"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6193-0218","authenticated-orcid":false,"given":"Andreia","family":"Pereira","sequence":"first","affiliation":[{"name":"Instituto de Telecomunica\u00e7\u00f5es (IT), 3810-193 Aveiro, Portugal"},{"name":"Department of Electrical and Computer Engineering (DEEC), University of Coimbra, 3030-290 Coimbra, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7994-6090","authenticated-orcid":false,"given":"Filipe","family":"Concei\u00e7\u00e3o","sequence":"additional","affiliation":[{"name":"Instituto de Telecomunica\u00e7\u00f5es (IT), 3810-193 Aveiro, Portugal"},{"name":"Department of Electrical and Computer Engineering (DEEC), University of Coimbra, 3030-290 Coimbra, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1124-525X","authenticated-orcid":false,"given":"Marco","family":"Gomes","sequence":"additional","affiliation":[{"name":"Instituto de Telecomunica\u00e7\u00f5es (IT), 3810-193 Aveiro, Portugal"},{"name":"Department of Electrical and Computer Engineering (DEEC), University of Coimbra, 3030-290 Coimbra, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8520-7267","authenticated-orcid":false,"given":"Rui","family":"Dinis","sequence":"additional","affiliation":[{"name":"Instituto de Telecomunica\u00e7\u00f5es (IT), 3810-193 Aveiro, Portugal"},{"name":"Faculdade de Ci\u00eancias e Tecnologia (FCT), Universidade Nova de Lisboa (UNL), 2829-516 Caparica, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2025,8,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1109\/MCOM.001.2000407","article-title":"Reconfigurable Intelligent Surfaces: Three Myths and Two Critical Questions","volume":"58","author":"Larsson","year":"2020","journal-title":"IEEE Commun. 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