{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T11:18:13Z","timestamp":1767093493844,"version":"build-2065373602"},"reference-count":43,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2021,8,14]],"date-time":"2021-08-14T00:00:00Z","timestamp":1628899200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"FCT\u2014Funda\u00e7\u00e3o para a Ci\u00eancia e Tecnologia","award":["UIDB\/00319\/2020","UIDB\/04077\/2020"],"award-info":[{"award-number":["UIDB\/00319\/2020","UIDB\/04077\/2020"]}]},{"name":"COMPETE2020, NORTE 2020, PORTUGAL 2020, and FEDER","award":["NORTE-01-0145-FEDER-030171"],"award-info":[{"award-number":["NORTE-01-0145-FEDER-030171"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fluids"],"abstract":"<jats:p>Cardiovascular diseases are a major cause of death and disability worldwide and they are commonly associated with the occurrence of atherosclerotic plaque deposition in the vessel walls, a process denoted as atherosclerosis. This is a chronic and progressive inflammatory disease of large-\/medium-sized blood vessels that affects blood flow profiles, with the abdominal aorta and its branches being one of the locations prone to the development of this pathology, due to their curvatures and bifurcations. In this regard, the effect of flow patterns was studied and compared for both a simplified three-dimensional model of aorta bifurcation on the iliac arteries and a realistic model of iliac bifurcation, which was constructed from a computational tomography medical image. The flow patterns were analyzed in terms of velocity and wall shear stress distribution, but a special focus was given to the size and location of the recirculation zone. The simulations were performed using the Computational Fluid Dynamics software, FLUENT, taking into account the cardiac cycle profile at the infrarenal aorta. The shear stress and the velocity distribution observed for both models indicated that higher shear stress occurred along the flow divider wall (inner wall) and low shear stress occurred along the outer walls. In addition, the results demonstrated that the wall shear stress profiles were deeply affected by the transient profile of the cardiac cycle, with the deceleration phase being the most critical phase to the occurrence of backflow.<\/jats:p>","DOI":"10.3390\/fluids6080284","type":"journal-article","created":{"date-parts":[[2021,8,15]],"date-time":"2021-08-15T21:43:55Z","timestamp":1629063835000},"page":"284","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Numerical Study of the Unsteady Flow in Simplified and Realistic Iliac Bifurcation Models"],"prefix":"10.3390","volume":"6","author":[{"given":"Violeta","family":"Carvalho","sequence":"first","affiliation":[{"name":"MEtRICs, Campus de Azur\u00e9m, University of Minho, 4800-058 Guimar\u00e3es, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4439-4166","authenticated-orcid":false,"given":"Filipa","family":"Carneiro","sequence":"additional","affiliation":[{"name":"PIEP-Innovation in Polymer Engineering, University of Minho, 4800-058 Guimar\u00e3es, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4775-5713","authenticated-orcid":false,"given":"Ana C.","family":"Ferreira","sequence":"additional","affiliation":[{"name":"MEtRICs, Campus de Azur\u00e9m, University of Minho, 4800-058 Guimar\u00e3es, Portugal"},{"name":"ALGORITMI Center, Campus de Azur\u00e9m, University of Minho, 4800-058 Guimar\u00e3es, Portugal"}]},{"given":"Vasco","family":"Gama","sequence":"additional","affiliation":[{"name":"Centro Hospitalar de Vila Nova de Gaia, Vilar de Andorinho, 4430-502 Vila Nova de Gaia, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8459-1837","authenticated-orcid":false,"given":"Jos\u00e9 C.","family":"Teixeira","sequence":"additional","affiliation":[{"name":"MEtRICs, Campus de Azur\u00e9m, University of Minho, 4800-058 Guimar\u00e3es, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7464-3944","authenticated-orcid":false,"given":"Senhorinha","family":"Teixeira","sequence":"additional","affiliation":[{"name":"ALGORITMI Center, Campus de Azur\u00e9m, University of Minho, 4800-058 Guimar\u00e3es, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2021,8,14]]},"reference":[{"key":"ref_1","first-page":"1","article-title":"Atherosclerosis","volume":"5","author":"Libby","year":"2019","journal-title":"Nat. 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