{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T20:08:09Z","timestamp":1771531689049,"version":"3.50.1"},"reference-count":92,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2021,9,23]],"date-time":"2021-09-23T00:00:00Z","timestamp":1632355200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["UID\/MULTI\/04046\/2019, UIDB\/04292\/2020 and PTDC\/BIA-BQM\/28539\/2017"],"award-info":[{"award-number":["UID\/MULTI\/04046\/2019, UIDB\/04292\/2020 and PTDC\/BIA-BQM\/28539\/2017"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["00819\/2015 to A.F., the PhD grants SFRH\/BD\/116900\/2016 to M.M., PD\/BD\/131030\/2017 to A.R.C. and SFRH\/BD\/145298\/2019 to G.L. and B.D. research contract (CEECIND\/00511\/2017"],"award-info":[{"award-number":["00819\/2015 to A.F., the PhD grants SFRH\/BD\/116900\/2016 to M.M., PD\/BD\/131030\/2017 to A.R.C. and SFRH\/BD\/145298\/2019 to G.L. and B.D. research contract (CEECIND\/00511\/2017"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Foods"],"abstract":"<jats:p>The domesticated species Vitis vinifera L. harbours many cultivars throughout the world that present distinctive phenology and grape quality. Not only have the grapes been used for human consumption, but the leaves are also used as a source of bioactive compounds and are present in the diets of several Mediterranean countries. We have selected seven different cultivars and performed elemental, fatty acid (FA) and pigment profiling. Total reflection X-ray fluorescence (TXRF) enabled the identification of 21 elements. Among them, Na, Ca and K were highly represented in all the cultivars and Zn was prevalent in V. vinifera cv. \u2018Pinot noir\u2019 and \u2018Cabernet sauvignon\u2019. Through gas chromatography, six FAs were identified, including omega-3 and omega-6 FA, the most abundant mainly in V. vinifera cv. \u2018Tinta barroca\u2019, \u2018Pinot noir\u2019 and \u2018Cabernet sauvignon\u2019. FA composition was used to determine nutritional quality parameters, namely atherogenic, thrombogenic, hypocholesterolemic\/hypercholesterolemic and peroxidisability indexes as well as oxidability and oxidative susceptibility. Grapevine leaves were highlighted as a suitable source of health-promoting lipids. Given the popularity of \u201cgreen\u201d diets, we have also performed a leaf pigment analysis. Seventeen pigments including chlorophylls, trans-lutein, b-carotene and zeaxanthins were detected. \u2018C19\u2019 presented the highest content of most of the detected pigments.<\/jats:p>","DOI":"10.3390\/foods10102251","type":"journal-article","created":{"date-parts":[[2021,9,23]],"date-time":"2021-09-23T09:59:15Z","timestamp":1632391155000},"page":"2251","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["More than Just Wine: The Nutritional Benefits of Grapevine Leaves"],"prefix":"10.3390","volume":"10","author":[{"given":"Marisa","family":"Maia","sequence":"first","affiliation":[{"name":"Grapevine Pathogen Systems Lab. (GPS Lab.), Biosystems and Integrative Sciences Institute (BioISI), Faculdade de Ci\u00eancias, Universidade de Lisboa, Campo Grande, 1749-016 Lisboa, Portugal"},{"name":"Departamento de Biologia Vegetal, Faculdade de Ci\u00eancias da Universidade de Lisboa, Campo Grande, 1749-016 Lisboa, Portugal"}]},{"given":"Ana Rita","family":"Cavaco","sequence":"additional","affiliation":[{"name":"Grapevine Pathogen Systems Lab. (GPS Lab.), Biosystems and Integrative Sciences Institute (BioISI), Faculdade de Ci\u00eancias, Universidade de Lisboa, Campo Grande, 1749-016 Lisboa, Portugal"},{"name":"Departamento de Biologia Vegetal, Faculdade de Ci\u00eancias da Universidade de Lisboa, Campo Grande, 1749-016 Lisboa, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6508-1919","authenticated-orcid":false,"given":"Gon\u00e7alo","family":"Laureano","sequence":"additional","affiliation":[{"name":"Grapevine Pathogen Systems Lab. (GPS Lab.), Biosystems and Integrative Sciences Institute (BioISI), Faculdade de Ci\u00eancias, Universidade de Lisboa, Campo Grande, 1749-016 Lisboa, Portugal"},{"name":"Departamento de Biologia Vegetal, Faculdade de Ci\u00eancias da Universidade de Lisboa, Campo Grande, 1749-016 Lisboa, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4248-5117","authenticated-orcid":false,"given":"Jorge","family":"Cunha","sequence":"additional","affiliation":[{"name":"Esta\u00e7\u00e3o Vitivin\u00edcola Nacional, Instituto Nacional de Investiga\u00e7\u00e3o Agr\u00e1ria e Veterin\u00e1ria (INIAV), Quinta da Almoinha, 2565-191 Dois Portos, Portugal"}]},{"given":"Jos\u00e9","family":"Eiras-Dias","sequence":"additional","affiliation":[{"name":"Esta\u00e7\u00e3o Vitivin\u00edcola Nacional, Instituto Nacional de Investiga\u00e7\u00e3o Agr\u00e1ria e Veterin\u00e1ria (INIAV), Quinta da Almoinha, 2565-191 Dois Portos, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3495-2195","authenticated-orcid":false,"given":"Ana Rita","family":"Matos","sequence":"additional","affiliation":[{"name":"Departamento de Biologia Vegetal, Faculdade de Ci\u00eancias da Universidade de Lisboa, Campo Grande, 1749-016 Lisboa, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1914-7435","authenticated-orcid":false,"given":"Bernardo","family":"Duarte","sequence":"additional","affiliation":[{"name":"Departamento de Biologia Vegetal, Faculdade de Ci\u00eancias da Universidade de Lisboa, Campo Grande, 1749-016 Lisboa, Portugal"},{"name":"MARE\u2014Marine and Environmental Sciences Centre, Faculdade de Ci\u00eancias da Universidade de Lisboa, Campo Grande, 1749-016 Lisboa, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8156-7700","authenticated-orcid":false,"given":"Andreia","family":"Figueiredo","sequence":"additional","affiliation":[{"name":"Grapevine Pathogen Systems Lab. (GPS Lab.), Biosystems and Integrative Sciences Institute (BioISI), Faculdade de Ci\u00eancias, Universidade de Lisboa, Campo Grande, 1749-016 Lisboa, Portugal"},{"name":"Departamento de Biologia Vegetal, Faculdade de Ci\u00eancias da Universidade de Lisboa, Campo Grande, 1749-016 Lisboa, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2021,9,23]]},"reference":[{"key":"ref_1","unstructured":"International Organisation of Vine and Wine (2021, July 31). 2020 Wine Production. OIV First Estimates. Available online: https:\/\/www.oiv.int\/public\/medias\/7541\/en-oiv-2020-world-wine-production-first-estimates.pdf."},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Bordiga, M. (2016). 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