{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T19:32:12Z","timestamp":1777577532766,"version":"3.51.4"},"reference-count":186,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2021,12,14]],"date-time":"2021-12-14T00:00:00Z","timestamp":1639440000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e Tecnologia","doi-asserted-by":"publisher","award":["PTDC\/OCE-ETA\/30240\/2017"],"award-info":[{"award-number":["PTDC\/OCE-ETA\/30240\/2017"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Foods"],"abstract":"<jats:p>Seaweeds represent a rich source of biologically active compounds with several applications, especially in the food, cosmetics, and medical fields. The beneficial effects of marine compounds on health have been increasingly explored, making them an excellent choice for the design of functional foods. When studying marine compounds, several aspects must be considered: extraction, identification and quantification methods, purification steps, and processes to increase their stability. Advanced green techniques have been used to extract these valuable compounds, and chromatographic methods have been developed to identify and quantify them. However, apart from the beneficial effects of seaweeds for human health, these natural sources of bioactive compounds can also accumulate undesirable toxic elements with potential health risks. Applying purification techniques of extracts from seaweeds may mitigate the amount of excessive toxic components, ensuring healthy and safer products for commercialization. Furthermore, limitations such as stability and bioavailability problems, chemical degradation reactions during storage, and sensitivity to oxidation and photo-oxidation, need to be overcome using, for example, nanoencapsulation techniques. Here we summarize recent advances in all steps of marine products identification and purification and highlight selected human applications, including food and feed applications, cosmetic, human health, and fertilizers, among others.<\/jats:p>","DOI":"10.3390\/foods10123100","type":"journal-article","created":{"date-parts":[[2021,12,14]],"date-time":"2021-12-14T09:34:25Z","timestamp":1639474465000},"page":"3100","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":60,"title":["Marine Health-Promoting Compounds: Recent Trends for Their Characterization and Human Applications"],"prefix":"10.3390","volume":"10","author":[{"given":"Eva","family":"Quit\u00e9rio","sequence":"first","affiliation":[{"name":"Ci\u00eancias Qu\u00edmicas e das Biomol\u00e9culas\/CISA, Escola Superior de Sa\u00fade\u2014Instituto Polit\u00e9cnico do Porto, Rua Doutor Ant\u00f3nio Bernardino de Almeida 400, 4200-072 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0924-9681","authenticated-orcid":false,"given":"Cristina","family":"Soares","sequence":"additional","affiliation":[{"name":"LAQV-REQUIMTE, Instituto Superior de Engenharia do Porto, Instituto Polit\u00e9cnico do Porto, Rua Doutor Ant\u00f3nio Bernardino de Almeida 431, 4249-015 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1761-117X","authenticated-orcid":false,"given":"Ricardo","family":"Ferraz","sequence":"additional","affiliation":[{"name":"Ci\u00eancias Qu\u00edmicas e das Biomol\u00e9culas\/CISA, Escola Superior de Sa\u00fade\u2014Instituto Polit\u00e9cnico do Porto, Rua Doutor Ant\u00f3nio Bernardino de Almeida 400, 4200-072 Porto, Portugal"},{"name":"LAQV-REQUIMTE, Departamento de Qu\u00edmica e Bioqu\u00edmica Faculdade de Ci\u00eancias, Universidade do Porto, R. do Campo Alegre, 4169-007 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3924-776X","authenticated-orcid":false,"given":"Cristina","family":"Delerue-Matos","sequence":"additional","affiliation":[{"name":"LAQV-REQUIMTE, Instituto Superior de Engenharia do Porto, Instituto Polit\u00e9cnico do Porto, Rua Doutor Ant\u00f3nio Bernardino de Almeida 431, 4249-015 Porto, Portugal"}]},{"given":"Clara","family":"Grosso","sequence":"additional","affiliation":[{"name":"LAQV-REQUIMTE, Instituto Superior de Engenharia do Porto, Instituto Polit\u00e9cnico do Porto, Rua Doutor Ant\u00f3nio Bernardino de Almeida 431, 4249-015 Porto, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2021,12,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2035","DOI":"10.1002\/jsfa.8798","article-title":"Chemical characterization of 21 species of marine macroalgae common in Norwegian waters: Benefits of and limitations to their potential use in food and feed","volume":"98","author":"Biancarosa","year":"2018","journal-title":"J. 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