{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T16:13:05Z","timestamp":1771949585132,"version":"3.50.1"},"reference-count":103,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2022,8,9]],"date-time":"2022-08-09T00:00:00Z","timestamp":1660003200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"European Regional Development Funds (FEDER)","award":["ED431C 2018\/05"],"award-info":[{"award-number":["ED431C 2018\/05"]}]},{"name":"European Regional Development Funds (FEDER)","award":["PCI2018-093245"],"award-info":[{"award-number":["PCI2018-093245"]}]},{"name":"Programa Iberoamericano de Ciencia y Tecnolog\u00eda para el Desarrollo (CyTED)","award":["ED431C 2018\/05"],"award-info":[{"award-number":["ED431C 2018\/05"]}]},{"name":"Programa Iberoamericano de Ciencia y Tecnolog\u00eda para el Desarrollo (CyTED)","award":["PCI2018-093245"],"award-info":[{"award-number":["PCI2018-093245"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Foods"],"abstract":"<jats:p>Although milk consumption is increasing worldwide, in some geographical regions, its consumption has persistently declined in recent decades. This fact, together with the increase in milk production prices, has caused both milk producers and the dairy industry to be immersed in a major crisis. Some possible solutions to this problem are to get people who do not currently consume milk to start drinking it again, or to market milk and dairy products with a higher added value. In this context, a type of milk called A2 has recently received attention from the industry. This type of milk, characterized by a difference in an amino acid at position 67 of the \u03b2-casein polypeptide chain, releases much smaller amounts of bioactive opioid peptide \u03b2-casomorphin 7 upon digestion, which has been linked to harmful effects on human health. Additionally, A2 milk has been attributed worse technological properties in the production of some dairy products. Thus, doubts exist about the convenience for the dairy industry to bet on this product. The aim of this review is to provide an update on the effects on human health of A2 milk, as well as its different technological properties to produce dairy products.<\/jats:p>","DOI":"10.3390\/foods11162387","type":"journal-article","created":{"date-parts":[[2022,8,10]],"date-time":"2022-08-10T02:42:53Z","timestamp":1660099373000},"page":"2387","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":48,"title":["A2 Milk: New Perspectives for Food Technology and Human Health"],"prefix":"10.3390","volume":"11","author":[{"given":"Salvador","family":"Fern\u00e1ndez-Rico","sequence":"first","affiliation":[{"name":"Laboratorio de Higiene Inspecci\u00f3n y Control de Alimentos, Departamento de Qu\u00edmica Anal\u00edtica, Nutrici\u00f3n y Bromatolog\u00eda, Universidad de Santiago de Compostela, 27002 Lugo, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1274-5539","authenticated-orcid":false,"given":"Alicia del Carmen","family":"Mondrag\u00f3n","sequence":"additional","affiliation":[{"name":"Laboratorio de Higiene Inspecci\u00f3n y Control de Alimentos, Departamento de Qu\u00edmica Anal\u00edtica, Nutrici\u00f3n y Bromatolog\u00eda, Universidad de Santiago de Compostela, 27002 Lugo, Spain"}]},{"given":"Aroa","family":"L\u00f3pez-Santamarina","sequence":"additional","affiliation":[{"name":"Laboratorio de Higiene Inspecci\u00f3n y Control de Alimentos, Departamento de Qu\u00edmica Anal\u00edtica, Nutrici\u00f3n y Bromatolog\u00eda, Universidad de Santiago de Compostela, 27002 Lugo, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1271-513X","authenticated-orcid":false,"given":"Alejandra","family":"Cardelle-Cobas","sequence":"additional","affiliation":[{"name":"Laboratorio de Higiene Inspecci\u00f3n y Control de Alimentos, Departamento de Qu\u00edmica Anal\u00edtica, Nutrici\u00f3n y Bromatolog\u00eda, Universidad de Santiago de Compostela, 27002 Lugo, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1584-9931","authenticated-orcid":false,"given":"Patricia","family":"Regal","sequence":"additional","affiliation":[{"name":"Laboratorio de Higiene Inspecci\u00f3n y Control de Alimentos, Departamento de Qu\u00edmica Anal\u00edtica, Nutrici\u00f3n y Bromatolog\u00eda, Universidad de Santiago de Compostela, 27002 Lugo, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7283-9372","authenticated-orcid":false,"given":"Alexandre","family":"Lamas","sequence":"additional","affiliation":[{"name":"Laboratorio de Higiene Inspecci\u00f3n y Control de Alimentos, Departamento de Qu\u00edmica Anal\u00edtica, Nutrici\u00f3n y Bromatolog\u00eda, Universidad de Santiago de Compostela, 27002 Lugo, Spain"}]},{"given":"Israel Samuel","family":"Ibarra","sequence":"additional","affiliation":[{"name":"\u00c1rea Acad\u00e9mica de Qu\u00edmica, Universidad Aut\u00f3noma del Estado de Hidalgo, Carretera Pachuca-Tulancingo Km. 4.5, Pachuca 42076, Hidalgo, Mexico"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9324-1342","authenticated-orcid":false,"given":"Alberto","family":"Cepeda","sequence":"additional","affiliation":[{"name":"Laboratorio de Higiene Inspecci\u00f3n y Control de Alimentos, Departamento de Qu\u00edmica Anal\u00edtica, Nutrici\u00f3n y Bromatolog\u00eda, Universidad de Santiago de Compostela, 27002 Lugo, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7992-1491","authenticated-orcid":false,"given":"Jos\u00e9 Manuel","family":"Miranda","sequence":"additional","affiliation":[{"name":"Laboratorio de Higiene Inspecci\u00f3n y Control de Alimentos, Departamento de Qu\u00edmica Anal\u00edtica, Nutrici\u00f3n y Bromatolog\u00eda, Universidad de Santiago de Compostela, 27002 Lugo, Spain"}]}],"member":"1968","published-online":{"date-parts":[[2022,8,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.cofs.2020.10.025","article-title":"Plant-based milk substitutes as emerging probiotic carriers","volume":"38","author":"Rasika","year":"2021","journal-title":"Curr. 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