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In parallel, there has been an increasing interest in the antioxidant properties of phytochemicals. Phytochemicals are products of plant secondary metabolism, including structural polysaccharides, unsaturated fatty acids, pigments (chlorophylls, carotenoids, and anthocyanins), or phenolic compounds. Phytochemicals can be obtained from lower and higher plants, their fruits, and even from macro- or microalgae. Their diverse structural features are linked to different beneficial effects through various molecular mechanisms, contributing to disease prevention. Beyond antioxidant activity, many phytochemicals also display anti-inflammatory, antidiabetic, anti-obesity, and neuroprotective effects, which can be intertwined. Beyond these, other natural antioxidants can also be obtained from animal, fungal, and bacterial sources. Thus, a wide range of antioxidants have the potential to be used as nutraceuticals with chemopreventive effects on the onset of various diseases related to antioxidant stress. Given their enormous structural and sourcing diversity, the present work provides an updated insight into the therapeutic and preventive potential of plant-derived antioxidants and nutraceuticals.<\/jats:p>","DOI":"10.3390\/foods14101749","type":"journal-article","created":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T12:22:17Z","timestamp":1747225337000},"page":"1749","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Therapeutic and Preventive Potential of Plant-Derived Antioxidant Nutraceuticals"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4095-7857","authenticated-orcid":false,"given":"Antia G.","family":"Pereira","sequence":"first","affiliation":[{"name":"Universidade de Vigo, Nutrition and Food Group (NuFoG), Department of Analytical Chemistry and Food Science, Instituto de Agroecolox\u00eda e Alimentaci\u00f3n (IAA)\u2014CITEXVI, 36310 Vigo, Spain"},{"name":"Investigaciones Agroalimentarias Research Group, Galicia Sur Health Research Institute (IIS Galicia Sur), SERGAS-UVIGO, 36312 Vigo, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1994-0436","authenticated-orcid":false,"given":"Javier","family":"Echave","sequence":"additional","affiliation":[{"name":"Universidade de Vigo, Nutrition and Food Group (NuFoG), Department of Analytical Chemistry and Food Science, Instituto de Agroecolox\u00eda e Alimentaci\u00f3n (IAA)\u2014CITEXVI, 36310 Vigo, Spain"},{"name":"Centro de Investiga\u00e7\u00e3o de Montanha (CIMO), LA SusTEC, Instituto Polit\u00e9cnico de Bragan\u00e7a, Campus de Santa Apol\u00f3nia, 5300-253 Bragan\u00e7a, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8511-5987","authenticated-orcid":false,"given":"Ana O. S.","family":"Jorge","sequence":"additional","affiliation":[{"name":"Universidade de Vigo, Nutrition and Food Group (NuFoG), Department of Analytical Chemistry and Food Science, Instituto de Agroecolox\u00eda e Alimentaci\u00f3n (IAA)\u2014CITEXVI, 36310 Vigo, Spain"},{"name":"REQUIMTE\/LAQV, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, R. Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal"}]},{"given":"Rafael","family":"Nogueira-Marques","sequence":"additional","affiliation":[{"name":"Universidade de Vigo, Nutrition and Food Group (NuFoG), Department of Analytical Chemistry and Food Science, Instituto de Agroecolox\u00eda e Alimentaci\u00f3n (IAA)\u2014CITEXVI, 36310 Vigo, Spain"}]},{"given":"Ezgi","family":"Nur Yuksek","sequence":"additional","affiliation":[{"name":"Universidade de Vigo, Nutrition and Food Group (NuFoG), Department of Analytical Chemistry and Food Science, Instituto de Agroecolox\u00eda e Alimentaci\u00f3n (IAA)\u2014CITEXVI, 36310 Vigo, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5795-8004","authenticated-orcid":false,"given":"Paula","family":"Barciela","sequence":"additional","affiliation":[{"name":"Universidade de Vigo, Nutrition and Food Group (NuFoG), Department of Analytical Chemistry and Food Science, Instituto de Agroecolox\u00eda e Alimentaci\u00f3n (IAA)\u2014CITEXVI, 36310 Vigo, Spain"}]},{"given":"Ana","family":"Perez-Vazquez","sequence":"additional","affiliation":[{"name":"Universidade de Vigo, Nutrition and Food Group (NuFoG), Department of Analytical Chemistry and Food Science, Instituto de Agroecolox\u00eda e Alimentaci\u00f3n (IAA)\u2014CITEXVI, 36310 Vigo, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2930-2531","authenticated-orcid":false,"given":"Franklin","family":"Chamorro","sequence":"additional","affiliation":[{"name":"Universidade de Vigo, Nutrition and Food Group (NuFoG), Department of Analytical Chemistry and Food Science, Instituto de Agroecolox\u00eda e Alimentaci\u00f3n (IAA)\u2014CITEXVI, 36310 Vigo, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6767-6596","authenticated-orcid":false,"given":"Maria B.","family":"P. 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Plant Antioxidants from Agricultural Waste: Synergistic Potential with Other Biological Properties and Possible Applications. Plant Antioxidants and Health, Springer."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/j.jff.2015.06.018","article-title":"Phenolics and Polyphenolics in Foods, Beverages and Spices: Antioxidant Activity and Health Effects\u2013A Review","volume":"18","author":"Shahidi","year":"2015","journal-title":"J. Funct. Foods"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"4853","DOI":"10.1039\/D0FO00937G","article-title":"Agriculture Waste Valorisation as a Source of Antioxidant Phenolic Compounds within a Circular and Sustainable Bioeconomy","volume":"11","author":"Carpena","year":"2020","journal-title":"Food Funct."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.1016\/j.freeradbiomed.2010.09.006","article-title":"Oxidative Stress, Inflammation, and Cancer: How Are They Linked?","volume":"49","author":"Reuter","year":"2010","journal-title":"Free Radic. Biol. Med."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.tifs.2014.07.012","article-title":"Role of Plant-Based Diets in the Prevention and Regression of Metabolic Syndrome and Neurodegenerative Diseases","volume":"40","author":"Pistollato","year":"2014","journal-title":"Trends Food Sci. Technol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"21138","DOI":"10.3390\/molecules201219753","article-title":"Antioxidant Phytochemicals for the Prevention and Treatment of Chronic Diseases","volume":"20","author":"Zhang","year":"2015","journal-title":"Molecules"},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Allaqaband, S., Dar, A.H., Patel, U., Kumar, N., Nayik, G.A., Khan, S.A., Ansari, M.J., Alabdallah, N.M., Kumar, P., and Pandey, V.K. (2022). Utilization of Fruit Seed-Based Bioactive Compounds for Formulating the Nutraceuticals and Functional Food: A Review. Front. Nutr., 9.","DOI":"10.3389\/fnut.2022.902554"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"100182","DOI":"10.1016\/j.ajpc.2021.100182","article-title":"Meta-Analysis of Effect of Vegetarian Diet on Ischemic Heart Disease and All-Cause Mortality","volume":"7","author":"Jabri","year":"2021","journal-title":"Am. J. Prev. Cardiol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"9926","DOI":"10.1080\/10408398.2022.2075311","article-title":"Evidence of a Vegan Diet for Health Benefits and Risks\u2013an Umbrella Review of Meta-Analyses of Observational and Clinical Studies","volume":"63","author":"Selinger","year":"2023","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.jbiotec.2018.06.349","article-title":"Extraction of Value-Added Components from Food Industry Based and Agro-Forest Biowastes by Deep Eutectic Solvents","volume":"282","author":"Malvis","year":"2018","journal-title":"J. Biotechnol."},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Oswell, N.J., Gunstone, F.D., and Pegg, R.B. (2020). Vegetable Oils. Bailey\u2019s Industrial Oil and Fat Products, Wiley.","DOI":"10.1002\/047167849X.bio018.pub2"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.indcrop.2018.11.030","article-title":"Chemical Characteristics and Compositions of Red Pepper Seed Oils Extracted by Different Methods","volume":"128","author":"Chouaibi","year":"2019","journal-title":"Ind. Crops Prod."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/1541-4337.12238","article-title":"Applications of Wine Pomace in the Food Industry: Approaches and Functions","volume":"16","year":"2017","journal-title":"Compr. Rev. Food Sci. Food Saf."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"102281","DOI":"10.1016\/j.algal.2021.102281","article-title":"A State-of-the-Art Review on the Synthetic Mechanisms, Production Technologies, and Practical Application of Polyunsaturated Fatty Acids from Microalgae","volume":"55","author":"Lu","year":"2021","journal-title":"Algal Res."},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Russo, G.L., Moccia, S., Russo, M., and Spagnuolo, C. (2021). Redox Regulation by Carotenoids: Evidence and Conflicts for Their Application in Cancer. Biochem. Pharmacol., 194.","DOI":"10.1016\/j.bcp.2021.114838"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1039\/9781849735506-00142","article-title":"Provitamin a Carotenoids: Occurrence, Intake and Bioavailability","volume":"1","author":"Bohn","year":"2012","journal-title":"Food Nutr. Components Focus"},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Poojary, M.M., Barba, F.J., Aliakbarian, B., Dons\u00ec, F., Pataro, G., Dias, D.A., and Juliano, P. (2016). Innovative Alternative Technologies to Extract Carotenoids from Microalgae and Seaweeds. Mar. Drugs, 14.","DOI":"10.3390\/md14110214"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.plipres.2018.04.004","article-title":"A Global Perspective on Carotenoids: Metabolism, Biotechnology, and Benefits for Nutrition and Health","volume":"70","author":"Avalos","year":"2018","journal-title":"Prog. Lipid Res."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"7000","DOI":"10.1021\/acs.jafc.1c01465","article-title":"Bioactive Dietary Fibers Selectively Promote Gut Microbiota to Exert Antidiabetic Effects","volume":"69","author":"Nie","year":"2021","journal-title":"J. Agric. Food Chem."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"14821","DOI":"10.3390\/molecules190914821","article-title":"Recovery of Biomolecules from Food Wastes\u2014A Review","volume":"19","author":"Baiano","year":"2014","journal-title":"Molecules"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1080\/10942912.2012.716475","article-title":"Physiological and Nutraceutical Perspectives of Fructan","volume":"18","author":"Saeed","year":"2015","journal-title":"Int. J. Food Prop."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"100258","DOI":"10.1016\/j.fochx.2022.100258","article-title":"Camellia Japonica: A Phytochemical Perspective and Current Applications Facing Its Industrial Exploitation","volume":"13","author":"Pereira","year":"2022","journal-title":"Food Chem. X"},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Salehi, B., Martorell, M., Arbiser, J.L., Sureda, A., Martins, N., Maurya, P.K., Sharifi-Rad, M., Kumar, P., and Sharifi-Rad, J. (2018). Antioxidants: Positive or Negative Actors?. Biomolecules, 8.","DOI":"10.3390\/biom8040124"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.jesf.2022.06.001","article-title":"Potential Harms of Supplementation with High Doses of Antioxidants in Athletes","volume":"20","author":"Li","year":"2022","journal-title":"J. Exerc. Sci. Fit."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Garc\u00eda-Cort\u00e9s, M., Robles-D\u00edaz, M., Ortega-Alonso, A., Medina-Caliz, I., and Andrade, R. (2016). Hepatotoxicity by Dietary Supplements: A Tabular Listing and Clinical Characteristics. Int. J. Mol. Sci., 17.","DOI":"10.3390\/ijms17040537"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1111\/j.1478-3231.2010.02439.x","article-title":"Review of Liver Injury Associated with Dietary Supplements","volume":"31","author":"Stickel","year":"2011","journal-title":"Liver Int."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1038\/s41557-018-0013-z","article-title":"Strategies for Microbial Synthesis of High-Value Phytochemicals","volume":"10","author":"Li","year":"2018","journal-title":"Nat. Chem."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"110871","DOI":"10.1016\/j.foodres.2021.110871","article-title":"Agro-Industrial by-Products: Valuable Sources of Bioactive Compounds","volume":"152","author":"Reguengo","year":"2022","journal-title":"Food Res. Int."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/B978-0-12-375083-9.00103-3","article-title":"Fatty Acids: Metabolism","volume":"Volume 2\u20134","author":"Watkins","year":"2013","journal-title":"Encyclopedia of Human Nutrition"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.2298\/JSC130402040R","article-title":"Polyunsaturated Fatty Acids in Health and Disease","volume":"78","author":"Vucic","year":"2013","journal-title":"J. Serbian Chem. Soc."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/B978-0-12-803678-5.00157-0","article-title":"Fatty Acids","volume":"Volume 3","author":"Moghadasian","year":"2017","journal-title":"International Encyclopedia of Public Health"},{"key":"ref_32","doi-asserted-by":"crossref","unstructured":"He, M., and Ding, N.Z. (2020). Plant Unsaturated Fatty Acids: Multiple Roles in Stress Response. Front. Plant Sci., 11.","DOI":"10.3389\/fpls.2020.562785"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.3390\/nu2121231","article-title":"Chemistry and Biochemistry of Dietary Polyphenols","volume":"2","author":"Tsao","year":"2010","journal-title":"Nutrients"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"128262","DOI":"10.1016\/j.foodchem.2020.128262","article-title":"Main Bioactive Phenolic Compounds in Marine Algae and Their Mechanisms of Action Supporting Potential Health Benefits","volume":"341","author":"Pereira","year":"2021","journal-title":"Food Chem."},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Di Lorenzo, C., Colombo, F., Biella, S., Stockley, C., and Restani, P. (2021). Polyphenols and Human Health: The Role of Bioavailability. Nutrients, 13.","DOI":"10.3390\/nu13010273"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"950","DOI":"10.3390\/i8090950","article-title":"Dietary Polyphenols and Their Biological Significance","volume":"8","author":"Han","year":"2007","journal-title":"Int. J. Mol. Sci."},{"key":"ref_37","doi-asserted-by":"crossref","unstructured":"Zhang, Z., Li, X., Sang, S., McClements, D.J., Chen, L., Long, J., Jiao, A., Jin, Z., and Qiu, C. (2022). Polyphenols as Plant-Based Nutraceuticals: Health Effects, Encapsulation, Nano-Delivery, and Application. Foods, 11.","DOI":"10.3390\/foods11152189"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1111\/j.1365-2621.2012.03067.x","article-title":"Phenolic Compounds in Fruits-an Overview","volume":"47","author":"Haminiuk","year":"2012","journal-title":"Int. J. Food Sci. Technol."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1111\/bph.13630","article-title":"Proanthocyanidins and Hydrolysable Tannins: Occurrence, Dietary Intake and Pharmacological Effects","volume":"174","author":"Smeriglio","year":"2017","journal-title":"Br. J. Pharmacol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"109298","DOI":"10.1016\/j.foodres.2020.109298","article-title":"Phenolic Acids from Vegetables: A Review on Processing Stability and Health Benefits","volume":"136","author":"Rashmi","year":"2020","journal-title":"Food Res. Int."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"2787","DOI":"10.2174\/1381612822666161227153906","article-title":"Phenolic Compounds as Nutraceuticals or Functional Food Ingredients","volume":"23","author":"Caleja","year":"2017","journal-title":"Curr. Pharm. Des."},{"key":"ref_42","unstructured":"Campos, M.R.S. (2019). Phenolic Compounds. Bioactive Compounds: Health Benefits and Potential Applications, Elsevier."},{"key":"ref_43","doi-asserted-by":"crossref","unstructured":"Sorrenti, V., Bur\u00f2, I., Consoli, V., and Vanella, L. (2023). Recent Advances in Health Benefits of Bioactive Compounds from Food Wastes and By-Products: Biochemical Aspects. Int. J. Mol. Sci., 24.","DOI":"10.3390\/ijms24032019"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1007\/978-0-387-28822-2_8","article-title":"Flavonoids as Nutraceuticals","volume":"7","author":"Lin","year":"2006","journal-title":"Sci. Flavonoids"},{"key":"ref_45","doi-asserted-by":"crossref","unstructured":"Dias, M., Roman\u00ed-P\u00e9rez, M., Roman\u00ed, A., de la Cruz, A., Pastrana, L., Fuci\u00f1os, P., and Amado, I.R. (2022). Recent Technological Advances in Phenolic Compounds Recovery and Applications: Source of Nutraceuticals for the Management of Diabetes. Appl. Sci., 12.","DOI":"10.3390\/app12189271"},{"key":"ref_46","doi-asserted-by":"crossref","unstructured":"Rahman, M.M., Rahaman, M.S., Islam, M.R., Rahman, F., Mithi, F.M., Alqahtani, T., Almikhlafi, M.A., Alghamdi, S.Q., Alruwaili, A.S., and Hossain, M.S. (2022). Role of Phenolic Compounds in Human Disease: Current Knowledge and Future Prospects. Molecules, 27.","DOI":"10.3390\/molecules27010233"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"100749","DOI":"10.1016\/j.focha.2024.100749","article-title":"A Review on the Influence of Nutraceuticals and Functional Foods on Health","volume":"5","author":"Vignesh","year":"2024","journal-title":"Food Chem. Adv."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11418-019-01364-x","article-title":"Carotenoids as Natural Functional Pigments","volume":"74","author":"Maoka","year":"2020","journal-title":"J. Nat. Med."},{"key":"ref_49","doi-asserted-by":"crossref","unstructured":"Crupi, P., Faienza, M.F., Naeem, M.Y., Corbo, F., Clodoveo, M.L., and Muraglia, M. (2023). Overview of the Potential Beneficial Effects of Carotenoids on Consumer Health and Well-Being. Antioxidants, 12.","DOI":"10.3390\/antiox12051069"},{"key":"ref_50","first-page":"3077","article-title":"Free Radical Chemistry of Carotenoids and Oxidative Stress Physiology of Cancer","volume":"Volume 1","author":"Chakraborti","year":"2022","journal-title":"Handbook of Oxidative Stress in Cancer: Therapeutic Aspects: Volume 1"},{"key":"ref_51","doi-asserted-by":"crossref","unstructured":"Srivastava, R. (2021). Physicochemical, Antioxidant Properties of Carotenoids and Its Optoelectronic and Interaction Studies with Chlorophyll Pigments. Sci. Rep., 11.","DOI":"10.1038\/s41598-021-97747-w"},{"key":"ref_52","doi-asserted-by":"crossref","unstructured":"Saini, R.K., Prasad, P., Lokesh, V., Shang, X., Shin, J., Keum, Y.S., and Lee, J.H. (2022). Carotenoids: Dietary Sources, Extraction, Encapsulation, Bioavailability, and Health Benefits\u2014A Review of Recent Advancements. Antioxidants, 11.","DOI":"10.3390\/antiox11040795"},{"key":"ref_53","doi-asserted-by":"crossref","unstructured":"Pereira, A.G., Otero, P., Echave, J., Carreira-Casais, A., Chamorro, F., Collazo, N., Jaboui, A., Louren\u00e7o-Lopes, C., Simal-Gandara, J., and Prieto, M.A. (2021). Xanthophylls from the Sea: Algae as Source of Bioactive Carotenoids. Mar. Drugs, 19.","DOI":"10.3390\/md19040188"},{"key":"ref_54","doi-asserted-by":"crossref","unstructured":"Widomska, J., Zareba, M., and Subczynski, W.K. (2016). Can Xanthophyll-Membrane Interactions Explain Their Selective Presence in the Retina and Brain?. Foods, 5.","DOI":"10.3390\/foods5010007"},{"key":"ref_55","doi-asserted-by":"crossref","unstructured":"Ojulari, O.V., Lee, S.G., and Nam, J.O. (2020). Therapeutic Effect of Seaweed Derived Xanthophyl Carotenoid on Obesity Management; Overview of the Last Decade. Int. J. Mol. Sci., 21.","DOI":"10.20944\/preprints202002.0349.v1"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.nupar.2021.10.002","article-title":"Understanding the Role of Vitamin A and Its Precursors in the Immune System","volume":"36","year":"2022","journal-title":"Nutr. Clin. Metab."},{"key":"ref_57","doi-asserted-by":"crossref","unstructured":"Jafari, S.M., Rashidinejad, A., and Simal-Gandara, J. (2023). Health Benefits of Beta-Carotene. Handbook of Food Bioactive Ingredients, Springer International Publishing.","DOI":"10.1007\/978-3-031-28109-9"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"117104","DOI":"10.1016\/j.lfs.2019.117104","article-title":"Xanthophyll: Health Benefits and Therapeutic Insights","volume":"240","author":"Aziz","year":"2020","journal-title":"Life Sci."},{"key":"ref_59","unstructured":"Rao, A.V., and Rao, L. (2024). Recent Advancement in Therapeutic Activity of Carotenoids. Dietary Carotenoids, IntechOpen."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"2268S","DOI":"10.3945\/jn.109.119024","article-title":"\u03b2-Carotene Is an Important Vitamin A Source for Humans","volume":"140","author":"Grune","year":"2010","journal-title":"J. Nutr."},{"key":"ref_61","doi-asserted-by":"crossref","unstructured":"Murphy, E.J., Fehrenbach, G.W., Abidin, I.Z., Buckley, C., Montgomery, T., Pogue, R., Murray, P., Major, I., and Rezoagli, E. (2023). Polysaccharides\u2014Naturally Occurring Immune Modulators. Polymers, 15.","DOI":"10.3390\/polym15102373"},{"key":"ref_62","doi-asserted-by":"crossref","unstructured":"Pedrosa, L.d.F., de Vos, P., and Fabi, J.P. (2023). Nature\u2019s Soothing Solution: Harnessing the Potential of Food-Derived Polysaccharides to Control Inflammation. Curr. Res. Struct. Biol., 6.","DOI":"10.1016\/j.crstbi.2023.100112"},{"key":"ref_63","doi-asserted-by":"crossref","unstructured":"Baghel, R.S., Choudhary, B., Pandey, S., Pathak, P.K., Patel, M.K., and Mishra, A. (2023). Rehashing Our Insight of Seaweeds as a Potential Source of Foods, Nutraceuticals, and Pharmaceuticals. Foods, 12.","DOI":"10.3390\/foods12193642"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1016\/j.ijbiomac.2019.10.114","article-title":"Structural Characterization and Antioxidant Effect of Green Alga Enteromorpha Prolifera Polysaccharide in Caenorhabditis Elegans via Modulation of MicroRNAs","volume":"150","author":"Lin","year":"2020","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_65","first-page":"8918914","article-title":"Sargassum Fusiforme Fucoidan SP2 Extends the Lifespan of Drosophila Melanogaster by Upregulating the Nrf2-Mediated Antioxidant Signaling Pathway","volume":"2019","author":"Zhang","year":"2019","journal-title":"Oxidative Med. Cell. Longev."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1039\/C6FO00027D","article-title":"Pleurotus Nebrodensis Polysaccharide(PN50G) Evokes A549 Cell Apoptosis by the ROS\/AMPK\/PI3K\/AKT\/MTOR Pathway to Suppress Tumor Growth","volume":"7","author":"Cui","year":"2016","journal-title":"Food Funct."},{"key":"ref_67","doi-asserted-by":"crossref","unstructured":"Zeng, F.S., Yao, Y.F., Wang, L.F., and Li, W.J. (2023). Polysaccharides as Antioxidants and Prooxidants in Managing the Double-Edged Sword of Reactive Oxygen Species. Biomed. Pharmacother., 159.","DOI":"10.1016\/j.biopha.2023.114221"},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"5692852","DOI":"10.1155\/2016\/5692852","article-title":"Reviews on Mechanisms of in Vitro Antioxidant Activity of Polysaccharides","volume":"2016","author":"Wang","year":"2016","journal-title":"Oxidative Med. Cell. Longev."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.cis.2016.05.009","article-title":"Encapsulation of Active Ingredients in Polysaccharide\u2013Protein Complex Coacervates","volume":"239","author":"Devi","year":"2017","journal-title":"Adv. Colloid Interface Sci."},{"key":"ref_70","doi-asserted-by":"crossref","unstructured":"Liu, Z., and Sun, X. (2020). A Critical Review of the Abilities, Determinants, and Possible Molecular Mechanisms of Seaweed Polysaccharides Antioxidants. Int. J. Mol. Sci., 21.","DOI":"10.3390\/ijms21207774"},{"key":"ref_71","doi-asserted-by":"crossref","unstructured":"Chen, N., Jiang, T., Xu, J., Xi, W., Shang, E., Xiao, P., and Duan, J.a. (2024). The Relationship between Polysaccharide Structure and Its Antioxidant Activity Needs to Be Systematically Elucidated. Int. J. Biol. Macromol., 270.","DOI":"10.1016\/j.ijbiomac.2024.132391"},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"120965","DOI":"10.1016\/j.carbpol.2023.120965","article-title":"The Antioxidant Activity of Polysaccharides: A Structure-Function Relationship Overview","volume":"314","author":"Fernandes","year":"2023","journal-title":"Carbohydr. Polym."},{"key":"ref_73","doi-asserted-by":"crossref","unstructured":"Bai, L., Xu, D., Zhou, Y.M., Zhang, Y.B., Zhang, H., Chen, Y.B., and Cui, Y.L. (2022). Antioxidant Activities of Natural Polysaccharides and Their Derivatives for Biomedical and Medicinal Applications. Antioxidants, 11.","DOI":"10.3390\/antiox11122491"},{"key":"ref_74","doi-asserted-by":"crossref","unstructured":"Niyigaba, T., Liu, D., and Habimana, J.d.D. (2021). The Extraction, Functionalities and Applications of Plant Polysaccharides in Fermented Foods: A Review. Foods, 10.","DOI":"10.3390\/foods10123004"},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"2626","DOI":"10.1080\/10408398.2021.1978385","article-title":"Application of Polysaccharide Biopolymers as Natural Adsorbent in Sample Preparation","volume":"63","author":"Sheibani","year":"2023","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"106392","DOI":"10.1016\/j.foodhyd.2020.106392","article-title":"Structural Characterization and Antioxidant Activity of Alkali-Extracted Polysaccharides from Quinoa","volume":"113","author":"Teng","year":"2021","journal-title":"Food Hydrocoll."},{"key":"ref_77","doi-asserted-by":"crossref","unstructured":"Bhuyan, P.P., Nayak, R., Patra, S., Abdulabbas, H.S., Jena, M., and Pradhan, B. (2023). Seaweed-Derived Sulfated Polysaccharides; The New Age Chemopreventives: A Comprehensive Review. Cancers, 15.","DOI":"10.3390\/cancers15030715"},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.tifs.2022.08.017","article-title":"Precision Nutrition: A Review of Current Approaches and Future Endeavors","volume":"128","author":"Livingstone","year":"2022","journal-title":"Trends Food Sci. Technol."},{"key":"ref_79","doi-asserted-by":"crossref","unstructured":"Rhazi, L., Depeint, F., and Gotor, A.A. (2022). Loss in the Intrinsic Quality and the Antioxidant Activity of Sunflower (Helianthus annuus L.) Oil during an Industrial Refining Process. Molecules, 27.","DOI":"10.3390\/molecules27030916"},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1080\/09637486.2016.1265099","article-title":"\u03b1-Tocopherol, \u03b2-Carotene, Lutein, Squalene and Secoiridoids in Seven Monocultivar Italian Extra-Virgin Olive Oils","volume":"68","author":"Ambra","year":"2017","journal-title":"Int. J. Food Sci. Nutr."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.bpc.2008.07.001","article-title":"Antioxidant Activity of Conjugated Linoleic Acid Isomers, Linoleic Acid and Its Methyl Ester Determined by Photoemission and DPPH Techniques","volume":"137","author":"Fagali","year":"2008","journal-title":"Biophys. Chem."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"22872","DOI":"10.3390\/molecules201219887","article-title":"Fatty Acid Profile and Biological Activities of Linseed and Rapeseed Oils","volume":"20","author":"Lewinska","year":"2015","journal-title":"Molecules"},{"key":"ref_83","doi-asserted-by":"crossref","unstructured":"Hulatt, C.J., Wijffels, R.H., Bolla, S., and Kiron, V. (2017). Production of Fatty Acids and Protein by Nannochloropsis in Flat-Plate Photobioreactors. PLoS ONE, 12.","DOI":"10.1371\/journal.pone.0170440"},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"131389","DOI":"10.1016\/j.foodchem.2021.131389","article-title":"Eicosapentaenoic Acid (EPA) Exhibits Antioxidant Activity via Mitochondrial Modulation","volume":"373","author":"Xiao","year":"2022","journal-title":"Food Chem."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1021\/acs.jafc.0c07751","article-title":"Antioxidant Activity of Docosahexaenoic Acid (DHA) and Its Regulatory Roles in Mitochondria","volume":"69","author":"Li","year":"2021","journal-title":"J. Agric. Food Chem."},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1007\/s10126-018-9849-x","article-title":"Functions of PKS Genes in Lipid Synthesis of Schizochytrium Sp. by Gene Disruption and Metabolomics Analysis","volume":"20","author":"Li","year":"2018","journal-title":"Mar. Biotechnol."},{"key":"ref_87","doi-asserted-by":"crossref","unstructured":"Rodrigues, N., Casal, S., Pinho, T., Cruz, R., Peres, A.M., Baptista, P., and Pereira, J.A. (2021). Fatty Acid Composition from Olive Oils of Portuguese Centenarian Trees Is Highly Dependent on Olive Cultivar and Crop Year. Foods, 10.","DOI":"10.3390\/foods10030496"},{"key":"ref_88","doi-asserted-by":"crossref","unstructured":"Petraru, A., Ursachi, F., and Amariei, S. (2021). Nutritional Characteristics Assessment of Sunflower Seeds, Oil and Cake. Perspective of Using Sunflower Oilcakes as a Functional Ingredient. Plants, 10.","DOI":"10.3390\/plants10112487"},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"712","DOI":"10.3109\/13880209.2011.621714","article-title":"Free Radical Scavenging Activity of Conjugated Linoleic Acid as Single or Mixed Isomers","volume":"50","author":"Ali","year":"2012","journal-title":"Pharm. Biol."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.biortech.2017.05.045","article-title":"Bioresource Technology Heterotrophy of Filamentous Oleaginous Microalgae Tribonema Minus for Potential Production of Lipid and Palmitoleic Acid","volume":"239","author":"Zhou","year":"2017","journal-title":"Bioresour. Technol."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/j.foodchem.2016.07.162","article-title":"Characterization of Arbequina Virgin Olive Oils Produced in Different Regions of Brazil and Spain: Physicochemical Properties, Oxidative Stability and Fatty Acid Profile","volume":"215","author":"Borges","year":"2017","journal-title":"Food Chem."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"103520","DOI":"10.1016\/j.jff.2019.103520","article-title":"A Review of Biological Functions, Health Benefits, and Possible de Novo Biosynthetic Pathway of Palmitoleic Acid in Macadamia Nuts","volume":"62","author":"Hu","year":"2019","journal-title":"J. Funct. Foods"},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"110","DOI":"10.3390\/appliedchem3010008","article-title":"Analysis of the Antioxidant Activity, Lipid Profile, and Minerals of the Skin and Seed of Hazelnuts (Corylus avellana L.), Pistachios (Pistacia vera) and Almonds (Prunus dulcis)\u2014A Comparative Analysis","volume":"3","author":"Mohammed","year":"2023","journal-title":"AppliedChem"},{"key":"ref_94","doi-asserted-by":"crossref","unstructured":"Shuai, X., Dai, T., Chen, M., Liang, R., Du, L., Chen, J., and Liu, C. (2021). Comparative Study of Chemical Compositions and Antioxidant Capacities of Oils Obtained from 15 Macadamia (Macadamia integrifolia) Cultivars in China. Foods, 10.","DOI":"10.3390\/foods10051031"},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"2078","DOI":"10.1002\/jsfa.9400","article-title":"Diversity of Oil Yield, Fatty Acids, Tocopherols, Tocotrienols, and Sterols in the Seeds of 19 Interspecific Grapes Crosses","volume":"99","author":"Grygier","year":"2019","journal-title":"J. Sci. Food Agric."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"2231","DOI":"10.1021\/jf0114381","article-title":"Antioxidant and Cyclooxygenase Activities of Fatty Acids Found in Food","volume":"50","author":"Henry","year":"2002","journal-title":"J. Agric. Food Chem."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/s12011-018-1526-4","article-title":"Oleic Acid Alleviates Cadmium-Induced Oxidative Damage in Rat by Its Radicals Scavenging Activity","volume":"190","author":"Wang","year":"2019","journal-title":"Biol. Trace Elem. Res."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1007\/978-3-319-39126-7_14","article-title":"Carotenoids as a Source of Antioxidants in the Diet","volume":"Volume 79","author":"Stange","year":"2016","journal-title":"Sub-Cellular Biochemistry"},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1080\/10942910903580918","article-title":"Carotenoid Profile, Total Phenolic Content, and Antioxidant Activity of Carrots","volume":"14","author":"Bozalan","year":"2011","journal-title":"Int. J. Food Prop."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.tifs.2021.03.012","article-title":"Biological Action Mechanisms of Fucoxanthin Extracted from Algae for Application in Food and Cosmetic Industries","volume":"117","author":"Carpena","year":"2021","journal-title":"Trends Food Sci. Technol."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"128","DOI":"10.3390\/md12010128","article-title":"Astaxanthin: Sources, Extraction, Stability, Biological Activities and Its Commercial Applications\u2014A Review","volume":"12","author":"Ambati","year":"2014","journal-title":"Mar. Drugs"},{"key":"ref_102","doi-asserted-by":"crossref","unstructured":"Iwamoto, H., Soccol, C.R., Molina-Aulestia, D.T., Cardoso, J., de Melo Pereira, G.V., de Souza Vandenberghe, L.P., Manzoki, M.C., Ambati, R.R., Ravishankar, G.A., and de Carvalho, J.C. (2024). Lutein from Microalgae: An Industrial Perspective of Its Production, Downstream Processing, and Market. Fermentation, 10.","DOI":"10.3390\/fermentation10020106"},{"key":"ref_103","doi-asserted-by":"crossref","unstructured":"Tudor, C., and Pintea, A. (2020). A Brief Overview of Dietary Zeaxanthin Occurrence and Bioaccessibility. Molecules, 25.","DOI":"10.3390\/molecules25184067"},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1093\/nutrit\/nuv064","article-title":"Absorption, Metabolism, and Functions of \u03b2-Cryptoxanthin","volume":"74","author":"Burri","year":"2016","journal-title":"Nutr. Rev."},{"key":"ref_105","doi-asserted-by":"crossref","unstructured":"Brahma, D., and Dutta, D. (2023). Evaluating \u03b2-Cryptoxanthin Antioxidant Properties against ROS-Induced Macromolecular Damages and Determining Its Photo-Stability and in-Vitro SPF. World J. Microbiol. Biotechnol., 39.","DOI":"10.1007\/s11274-023-03747-5"},{"key":"ref_106","doi-asserted-by":"crossref","unstructured":"Galla, R., Ruga, S., Aprile, S., Ferrari, S., Brovero, A., Grosa, G., Molinari, C., and Uberti, F. (2022). New Hyaluronic Acid from Plant Origin to Improve Joint Protection\u2014An In Vitro Study. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms23158114"},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1016\/j.matpr.2021.12.038","article-title":"Identification and Antioxidant Activity of Hyaluronic Acid Extracted from Local Isolates of Streptococcus Thermophilus","volume":"60","author":"Mohammed","year":"2022","journal-title":"Mater. Today Proc."},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1007\/s00253-010-2677-1","article-title":"Production of Chondroitin Sulfate and Chondroitin","volume":"87","author":"Schiraldi","year":"2010","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/S1054-3589(05)53020-5","article-title":"Antioxidant Activity of Chondroitin Sulfate","volume":"Volume 53","author":"Campo","year":"2006","journal-title":"Advances in Pharmacology"},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4137\/GBI.S9705","article-title":"Challenges for Heparin Production: Artificial Synthesis or Alternative Natural Sources?","volume":"3","year":"2012","journal-title":"Glycobiol. Insights"},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.cbi.2016.07.022","article-title":"Popular Naturally Occurring Antioxidants as Potential Anticoagulant Drugs","volume":"257","author":"Bijak","year":"2016","journal-title":"Chem. Biol. Interact."},{"key":"ref_112","doi-asserted-by":"crossref","unstructured":"Medlej, M.K., Batoul, C., Olleik, H., Li, S., Hijazi, A., Nasser, G., Maresca, M., and Pochat-Bohatier, C. (2021). Antioxidant Activity and Biocompatibility of Fructo-Polysaccharides Extracted from a Wild Species of Ornithogalum from Lebanon. Antioxidants, 10.","DOI":"10.3390\/antiox10010068"},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1590\/S1516-89132011000600002","article-title":"Galactans: An Overview of Their Most Important Sourcing and Applications as Natural Polysaccharides","volume":"54","author":"Delattre","year":"2011","journal-title":"Brazilian Arch. Biol. Technol."},{"key":"ref_114","first-page":"10","article-title":"Sources of Pectin, Extraction and Its Applications in Pharmaceutical Industry\u2014an Overview","volume":"2","author":"Srivastava","year":"2011","journal-title":"Indian J. Nat. Prod. Resour."},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"e02299","DOI":"10.1016\/j.heliyon.2019.e02299","article-title":"Characterization and Antioxidant Activity of Pectin from Indonesian Mangosteen (Garcinia mangostana L.) Rind","volume":"5","author":"Wathoni","year":"2019","journal-title":"Heliyon"},{"key":"ref_116","first-page":"37","article-title":"Antioxidant and Antibacterial Properties of Bacterial Cellulose-Indonesian Plant Extract Composites for Mask Sheet","volume":"10","author":"Indrianingsih","year":"2020","journal-title":"J. Appl. Pharm. Sci."},{"key":"ref_117","doi-asserted-by":"crossref","first-page":"1568","DOI":"10.1021\/acs.biomac.0c00127","article-title":"Bacterial Cellulose-Chitosan Paper with Antimicrobial and Antioxidant Activities","volume":"21","author":"Valls","year":"2020","journal-title":"Biomacromolecules"},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"2100165","DOI":"10.1002\/star.202100165","article-title":"Synthesis of Nanocapsules Based on Biosynthesized Nickel Nanoparticles and Potato Starch: Antimicrobial, Antioxidant, and Anticancer Activity","volume":"74","author":"Hashem","year":"2022","journal-title":"Starch\/Staerke"},{"key":"ref_119","first-page":"69","article-title":"Natural Sources of Health-Promoting Starch Natural Sources of Health-Promoting Starch","volume":"45","author":"Kraic","year":"2018","journal-title":"J. Food Nutr. Res."},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1021\/bm500038g","article-title":"Properties, Chemistry, and Applications of the Bioactive Polysaccharide Curdlan","volume":"15","author":"Zhang","year":"2014","journal-title":"Biomacromolecules"},{"key":"ref_121","doi-asserted-by":"crossref","unstructured":"Li, H., Xu, S., Xie, Y., Zhang, Q., Ding, S., Wang, R., Fu, F., and Zhan, X. (2024). Curdlan-Polyphenol Complexes Prepared by PH-Driven Effectively Enhanced Their Physicochemical Stability, Antioxidant and Prebiotic Activities. Int. J. Biol. Macromol., 267.","DOI":"10.1016\/j.ijbiomac.2024.131579"},{"key":"ref_122","first-page":"278","article-title":"Production of Dextran from Locally Lactobacillus Spp. Isolates","volume":"8","author":"Kareem","year":"2019","journal-title":"Reports Biochem. Mol. Biol."},{"key":"ref_123","doi-asserted-by":"crossref","unstructured":"Rosca, I., Turin-Moleavin, I.A., Sarghi, A., Lungoci, A.L., Varganici, C.D., Petrovici, A.R., Fifere, A., and Pinteala, M. (2024). Dextran Coated Iron Oxide Nanoparticles Loaded with Protocatechuic Acid as Multifunctional Therapeutic Agents. Int. J. Biol. Macromol., 256.","DOI":"10.1016\/j.ijbiomac.2023.128314"},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0141-3910(97)00197-3","article-title":"Production and Application of Microbial Cellulose","volume":"59","author":"Jonas","year":"1998","journal-title":"Polym. Degrad. Stab."},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1111\/j.1753-4887.2009.00230.x","article-title":"Beta-Glucans in Higher Fungi and Their Health Effects","volume":"67","author":"Rop","year":"2009","journal-title":"Nutr. Rev."},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"58","DOI":"10.5138\/09750185.2229","article-title":"Antioxidant, Anti-Cholinesterase, Anti-\u03b1-Glucosidase and Prebiotic Properties of Beta-Glucan Extracted from Algerian Barley","volume":"10","author":"Mebrek","year":"2018","journal-title":"Int. J. Phytomedicine"},{"key":"ref_127","first-page":"85","article-title":"Sources, Production and Commercial Applications of Fungal Chitosan: A Review","volume":"7","author":"Huq","year":"2022","journal-title":"J. Bioresour. Bioprod."},{"key":"ref_128","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1016\/j.bmc.2004.11.002","article-title":"Antioxidant Activity of Differently Regioselective Chitosan Sulfates in Vitro","volume":"13","author":"Xing","year":"2005","journal-title":"Bioorganic Med. Chem."},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s10811-006-9121-z","article-title":"Antioxidant Activities of Sulfated Polysaccharides from Brown and Red Seaweeds","volume":"19","author":"Marques","year":"2007","journal-title":"J. Appl. Phycol."},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.ijbiomac.2022.12.261","article-title":"Extraction of High Purity Fucoidans from Brown Seaweeds Using Cellulases and Alginate Lyases","volume":"229","author":"Horn","year":"2023","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_131","doi-asserted-by":"crossref","unstructured":"Pereira, L., and COTAS, J. (2019). Alginates-Recent Uses of This Natural Polymer, IntechOpen.","DOI":"10.5772\/intechopen.77849"},{"key":"ref_132","doi-asserted-by":"crossref","unstructured":"El-Sheekh, M., Kassem, W.M.A., Alwaleed, E.A., and Saber, H. (2024). Optimization and Characterization of Brown Seaweed Alginate for Antioxidant, Anticancer, Antimicrobial, and Antiviral Properties. Int. J. Biol. Macromol., 278.","DOI":"10.1016\/j.ijbiomac.2024.134715"},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"3353","DOI":"10.1007\/s10570-024-05816-w","article-title":"The Potential of Algae as a Source of Cellulose and Its Derivatives for Biomedical Applications","volume":"31","author":"Machado","year":"2024","journal-title":"Cellulose"},{"key":"ref_134","doi-asserted-by":"crossref","first-page":"103011","DOI":"10.1016\/j.algal.2023.103011","article-title":"Extraction, Antioxidant Activity, and Hydrogel Formulation of Marine Cladophora Glomerata","volume":"71","author":"Petchsomrit","year":"2023","journal-title":"Algal Res."},{"key":"ref_135","first-page":"346","article-title":"Quantification of Phenolic Compounds, Evaluation of Physicochemical Properties and Antioxidant Activity of Four Date (Phoenix dactylifera L.) Varieties of Oman","volume":"10","author":"Mavazhe","year":"2015","journal-title":"J. Taibah Univ. Med. Sci."},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.bcab.2018.07.011","article-title":"Enhancement of Antioxidant Properties from Green Coffee as Promising Ingredient for Food and Cosmetic Industries","volume":"16","author":"Palmieri","year":"2018","journal-title":"Biocatal. Agric. Biotechnol."},{"key":"ref_137","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1089\/jmf.2016.3790","article-title":"Antioxidant, Antidiabetic, and Antihypertensive Properties of Echinacea Purpurea Flower Extract and Caffeic Acid Derivatives Using in Vitro Models","volume":"20","author":"Chiou","year":"2017","journal-title":"J. Med. Food"},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"e14158","DOI":"10.1111\/jfpe.14158","article-title":"Extraction of Ferulic Acid from Rice Bran Using NADES-Ultrasound-Assisted Extraction: Kinetics and Optimization","volume":"46","author":"Gharat","year":"2023","journal-title":"J. Food Process Eng."},{"key":"ref_139","doi-asserted-by":"crossref","unstructured":"Rivero-Cruz, J.F., Granados-Pineda, J., Pedraza-Chaverri, J., P\u00e9rez-Rojas, J.M., Kumar-Passari, A., Diaz-Ruiz, G., and Rivero-Cruz, B.E. (2020). Phytochemical Constituents, Antioxidant, Cytotoxic, and Antimicrobial Activities of the Ethanolic Extract of Mexican Brown Propolis. Antioxidants, 9.","DOI":"10.3390\/antiox9010070"},{"key":"ref_140","doi-asserted-by":"crossref","unstructured":"Priyandoko, D., Widowati, W., Kusuma, H.S.W., Afifah, E., Wijayanti, C.R., Wahyuni, C.D., Idris, A.M., Putdayani, R.A., and Rizal, R. (2021, January 14\u201316). Antioxidant Activity of Green Tea Extract and Myricetin. Proceedings of the InHeNce 2021\u20142021 IEEE International Conference on Health, Instrumentation and Measurement, and Natural Sciences, Medan, Indonesia.","DOI":"10.1109\/InHeNce52833.2021.9537285"},{"key":"ref_141","doi-asserted-by":"crossref","unstructured":"Dou, X., Zhou, Z., Ren, R., and Xu, M. (2020). Apigenin, Flavonoid Component Isolated from Gentiana Veitchiorum Flower Suppresses the Oxidative Stress through LDLR-LCAT Signaling Pathway. Biomed. Pharmacother., 128.","DOI":"10.1016\/j.biopha.2020.110298"},{"key":"ref_142","doi-asserted-by":"crossref","first-page":"e18806","DOI":"10.1016\/j.heliyon.2023.e18806","article-title":"Phytochemical Profile and Antioxidant Activity of Various Solvent Extracts of Two Varieties of Ginger and Garlic","volume":"9","author":"Akullo","year":"2023","journal-title":"Heliyon"},{"key":"ref_143","doi-asserted-by":"crossref","first-page":"301","DOI":"10.33084\/bjop.v4i4.2497","article-title":"Correlation Analysis of Antioxidant Activities with Tannin, Total Flavonoid, and Total Phenolic Contents of Nutmeg (Myristica Fragrans Houtt) Fruit Precipitated by Egg White","volume":"4","author":"Antasionasti","year":"2021","journal-title":"Borneo J. Pharm."},{"key":"ref_144","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1038\/s41405-023-00157-5","article-title":"The Potential Preventive Effect of Dietary Phytochemicals In Vivo","volume":"9","author":"Saleh","year":"2023","journal-title":"BDJ Open"},{"key":"ref_145","doi-asserted-by":"crossref","unstructured":"Molina-Montes, E., Salamanca-Fern\u00e1ndez, E., Garcia-Villanova, B., and S\u00e1nchez, M.J. (2020). The Impact of Plant-based Dietary Patterns on Cancer-related Outcomes: A Rapid Review and Meta-analysis. Nutrients, 12.","DOI":"10.3390\/nu12072010"},{"key":"ref_146","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1159\/000490019","article-title":"Allicin Inhibits Proliferation and Invasion in Vitro and in Vivo via SHP-1-Mediated STAT3 Signaling in Cholangiocarcinoma","volume":"47","author":"Chen","year":"2018","journal-title":"Cell. Physiol. Biochem."},{"key":"ref_147","first-page":"1405","article-title":"The Resveratrol Analogue, HS-1793, Enhances the Effects of Radiation Therapy through the Induction of Anti-Tumor Immunity in Mammary Tumor Growth","volume":"56","author":"Kim","year":"2020","journal-title":"Int. J. Oncol."},{"key":"ref_148","unstructured":"Bone, S.M.K. (2013). Principles of Herbal Pharmacology. Principles and Practice of Phytotherapy, Elsevier."},{"key":"ref_149","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1093\/molehr\/gav065","article-title":"Can Dicoumarol Be Used as a Gonad-Safe Anticancer Agent: An in Vitro and in Vivo Experimental Study","volume":"22","author":"Aras","year":"2015","journal-title":"Mol. Hum. Reprod."},{"key":"ref_150","doi-asserted-by":"crossref","unstructured":"Chen, Y.C., Chia, Y.C., and Huang, B.M. (2021). Phytochemicals from Polyalthia Species: Potential and Implication on Anti-Oxidant, Anti-Inflammatory, Anti-Cancer, and Chemoprevention Activities. Molecules, 26.","DOI":"10.3390\/molecules26175369"},{"key":"ref_151","doi-asserted-by":"crossref","unstructured":"Lam, M., Carmichael, A.R., and Griffiths, H.R. (2012). An Aqueous Extract of Fagonia Cretica Induces DNA Damage, Cell Cycle Arrest and Apoptosis in Breast Cancer Cells via FOXO3a and P53 Expression. PLoS ONE, 7.","DOI":"10.1371\/journal.pone.0040152"},{"key":"ref_152","doi-asserted-by":"crossref","first-page":"102337","DOI":"10.1016\/j.eujim.2024.102337","article-title":"Phytochemical Profile by LC-MS\/MS Analysis and Evaluation of Antioxidant, Antidiabetic, Anti-Alzheimer, and Anticancer Activity of Onobrychis Argyrea Leaf Extracts","volume":"66","author":"Altay","year":"2024","journal-title":"Eur. J. Integr. Med."},{"key":"ref_153","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/j.jep.2011.04.001","article-title":"Cytotoxic, Apoptotic and Anti-\u03b1-Glucosidase Activities of 3,4-Di-O-Caffeoyl Quinic Acid, an Antioxidant Isolated from the Polyphenolic-Rich Extract of Elephantopus Mollis Kunth","volume":"135","author":"Ooi","year":"2011","journal-title":"J. Ethnopharmacol."},{"key":"ref_154","doi-asserted-by":"crossref","first-page":"7882","DOI":"10.20964\/2018.08.57","article-title":"Determination of Total Phenolics Contents, Antioxidant Capacity of Thymus Vulgaris Extracts Using Electrochemical and Spectrophotometric Methods","volume":"13","author":"Amamra","year":"2018","journal-title":"Int. J. Electrochem. Sci."},{"key":"ref_155","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1186\/s43094-024-00679-1","article-title":"Chemical Profile, Antioxidant and Anti-Alzheimer Activity of Leaves and Flowers of Markhamia Lutea Cultivated in Egypt: In Vitro and in Silico Studies","volume":"10","author":"Magdy","year":"2024","journal-title":"Futur. J. Pharm. Sci."},{"key":"ref_156","doi-asserted-by":"crossref","unstructured":"Abdelouhab, K., Guemmaz, T., Karama\u0107, M., Kati, D.E., Amarowicz, R., and Arrar, L. (2023). Phenolic Composition and Correlation with Antioxidant Properties of Various Organic Fractions from Hertia Cheirifolia Extracts. J. Pharm. Biomed. Anal., 235.","DOI":"10.1016\/j.jpba.2023.115673"},{"key":"ref_157","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1007\/s11033-015-3921-7","article-title":"Anticarcinogenic Action of Quercetin by Downregulation of Phosphatidylinositol 3-Kinase (PI3K) and Protein Kinase C (PKC) via Induction of P53 in Hepatocellular Carcinoma (HepG2) Cell Line","volume":"42","author":"Maurya","year":"2015","journal-title":"Mol. Biol. Rep."},{"key":"ref_158","doi-asserted-by":"crossref","unstructured":"Reimche, I., Yu, H., Ariantari, N.P., Liu, Z., Merkens, K., Rotfu\u00df, S., Peter, K., Jungwirth, U., Bauer, N., and Kiefer, F. (2022). Phenanthroindolizidine Alkaloids Isolated from Tylophora Ovata as Potent Inhibitors of Inflammation, Spheroid Growth, and Invasion of Triple-Negative Breast Cancer. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms231810319"},{"key":"ref_159","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.jff.2019.01.035","article-title":"Polyphenols from Mango (Mangifera indica L.) Modulate PI3K\/AKT\/MTOR-Associated Micro-RNAs and Reduce Inflammation in Non-Cancer and Induce Cell Death in Breast Cancer Cells","volume":"55","author":"Kim","year":"2019","journal-title":"J. Funct. Foods"},{"key":"ref_160","first-page":"476","article-title":"Chemopreventive and Biological Activities of Helicteres Isora L. Fruit Extracts","volume":"13","author":"Rattanamaneerusmee","year":"2018","journal-title":"Res. Pharm. Sci."},{"key":"ref_161","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.jep.2017.03.048","article-title":"Cancer Chemopreventive Activity of Compounds Isolated from Waltheria Indica","volume":"203","author":"Monteillier","year":"2017","journal-title":"J. Ethnopharmacol."},{"key":"ref_162","doi-asserted-by":"crossref","first-page":"118025","DOI":"10.1016\/j.jep.2024.118025","article-title":"Chemopreventive and Immunomodulatory Effects of Phenolic-Rich Extract of Commiphora Leptophloeos against Inflammatory Bowel Disease: Preclinical Evidence","volume":"328","author":"Guerra","year":"2024","journal-title":"J. Ethnopharmacol."},{"key":"ref_163","doi-asserted-by":"crossref","unstructured":"Drif, A.I., Y\u00fccer, R., Damiescu, R., Ali, N.T., Abu Hagar, T.H., Avula, B., Khan, I.A., and Efferth, T. (2024). Anti-Inflammatory and Cancer-Preventive Potential of Chamomile (Matricaria chamomilla L.): A Comprehensive In Silico and In Vitro Study. Biomedicines, 12.","DOI":"10.3390\/biomedicines12071484"},{"key":"ref_164","doi-asserted-by":"crossref","unstructured":"Sobhy, Y.S., Abo-zeid, Y.S., Mahgoub, S.S., Mina, S.A., and Mady, M.S. (2024). In-vitro Cytotoxic and Anti-inflammatory Potential of Asparagus Densiflorus Meyeri and Its Phytochemical Investigation. Chem. Biodivers., 21.","DOI":"10.1002\/cbdv.202400959"},{"key":"ref_165","doi-asserted-by":"crossref","first-page":"100502","DOI":"10.1016\/j.phyplu.2023.100502","article-title":"Capparis Cartilaginea Decne. as a Natural Source of Antioxidant, Anti-Inflammatory, and Anti-Cancer Herbal Drug","volume":"4","author":"Thamer","year":"2024","journal-title":"Phytomedicine Plus"},{"key":"ref_166","doi-asserted-by":"crossref","first-page":"100567","DOI":"10.1016\/j.phyplu.2024.100567","article-title":"Pro-Estrogenic and Anti-Inflammatory Effects of Corchorus Olitorius and Amaranthus Hybridus Leaves in DMBA-Induced Breast Cancer","volume":"4","author":"Dania","year":"2024","journal-title":"Phytomedicine Plus"},{"key":"ref_167","doi-asserted-by":"crossref","first-page":"14567","DOI":"10.3390\/molecules190914567","article-title":"Evaluation of the Antioxidant, Anti-Inflammatory, and Anticancer Activities of Euphorbia Hirta Ethanolic Extract","volume":"19","author":"Sharma","year":"2014","journal-title":"Molecules"},{"key":"ref_168","doi-asserted-by":"crossref","first-page":"105703","DOI":"10.1016\/j.arabjc.2024.105703","article-title":"HPLC Profiling for the Simultaneous Estimation of Antidiabetic Compounds from Tradescantia Pallida","volume":"17","author":"Imtiaz","year":"2024","journal-title":"Arab. J. Chem."},{"key":"ref_169","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/j.sajb.2023.11.003","article-title":"Phytochemical Composition and Antidiabetic Potential of the Leaf, Stem, and Rhizome Extracts of Cissampelos Capensis L.F","volume":"163","author":"Latolla","year":"2023","journal-title":"S. Afr. J. Bot."},{"key":"ref_170","doi-asserted-by":"crossref","first-page":"112268","DOI":"10.1016\/j.jep.2019.112268","article-title":"In Silico Screening of Potential Antidiabetic Phytochemicals from Phyllanthus Emblica against Therapeutic Targets of Type 2 Diabetes","volume":"248","author":"Sharma","year":"2020","journal-title":"J. Ethnopharmacol."},{"key":"ref_171","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1677\/joe.1.06615","article-title":"Ocimum Sanctum Leaf Extracts Stimulate Insulin Secretion from Perfused Pancreas, Isolated Islets and Clonal Pancreatic \u03b2-Cells","volume":"189","author":"Hannan","year":"2006","journal-title":"J. Endocrinol."},{"key":"ref_172","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1177\/0748233711403193","article-title":"Hypoglycemic Effect of Basil (Ocimum basilicum) Aqueous Extract Is Mediated through Inhibition of \u03b1-Glucosidase and \u03b1-Amylase Activities: An in Vitro Study","volume":"28","author":"Bahashwan","year":"2012","journal-title":"Toxicol. Ind. Health"},{"key":"ref_173","doi-asserted-by":"crossref","first-page":"102016","DOI":"10.1016\/j.jsps.2024.102016","article-title":"Exploring the Therapeutic Potential of Derris elliptica (Wall.) Benth in Streptozotocin-Induced Diabetic Rats: Phytochemical Characterization and Antidiabetic Evaluation: Exploring the Therapeutic Potential of Derris elliptica (Wall.)","volume":"32","author":"Rahman","year":"2024","journal-title":"Saudi Pharm. J."},{"key":"ref_174","doi-asserted-by":"crossref","first-page":"101342","DOI":"10.1016\/j.jksus.2021.101342","article-title":"Antioxidant and Anti-Diabetic Activities of Bioactive Fractions of Carica Papaya Seeds Extract","volume":"33","author":"Agada","year":"2021","journal-title":"J. King Saud Univ.-Sci."},{"key":"ref_175","doi-asserted-by":"crossref","unstructured":"Mahmood, R., Kayani, W.K., Ahmed, T., Malik, F., Hussain, S., Ashfaq, M., Ali, H., Rubnawaz, S., Green, B.D., and Calderwood, D. (2020). Assessment of Antidiabetic Potential and Phytochemical Profiling of Rhazya Stricta Root Extracts. BMC Complement. Med. Ther., 20.","DOI":"10.1186\/s12906-020-03035-x"},{"key":"ref_176","doi-asserted-by":"crossref","unstructured":"Rizvi, S.N.R., Afzal, S., Khan, K.U.R., Aati, H.Y., Rao, H., Ghalloo, B.A., Shahzad, M.N., Khan, D.A., Esatbeyoglu, T., and Korma, S.A. (2023). Chemical Characterisation, Antidiabetic, Antibacterial, and In Silico Studies for Different Extracts of Haloxylon stocksii (Boiss.) Benth: A Promising Halophyte. Molecules, 28.","DOI":"10.3390\/molecules28093847"},{"key":"ref_177","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.nutres.2023.09.002","article-title":"Rose Polyphenols Exert Antiobesity Effect in High-Fat\u2013Induced Obese Mice by Regulating Lipogenic Gene Expression","volume":"119","author":"Ye","year":"2023","journal-title":"Nutr. Res."},{"key":"ref_178","doi-asserted-by":"crossref","unstructured":"Fang, J.Y., Huang, T.H., Chen, W.J., Aljuffali, I.A., and Hsu, C.Y. (2022). Rhubarb Hydroxyanthraquinones Act as Antiobesity Agents to Inhibit Adipogenesis and Enhance Lipolysis. Biomed. Pharmacother., 146.","DOI":"10.1016\/j.biopha.2021.112497"},{"key":"ref_179","doi-asserted-by":"crossref","unstructured":"Im, J.H., Lim, J.s., Han, X., Men, X., Oh, G., Fu, X., Cho, G.h., Hwang, W.s., Choi, S.I., and Lee, O.H. (2024). Anti-Obesogenic Effect of Standardized Brassica Juncea Extract on Bisphenol A-Induced 3T3-L1 Preadipocytes and C57BL\/6J Obese Mice. Food Sci. Biotechnol., 16.","DOI":"10.1007\/s10068-024-01688-9"},{"key":"ref_180","first-page":"e02051","article-title":"Evaluation of the Antidiabetic, Antiobesity and Antioxidant Potential of Anthophycus Longifolius ((Turner) K\u00fctzing)","volume":"23","author":"Magwaza","year":"2024","journal-title":"Sci. African"},{"key":"ref_181","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5455\/njppp.2023.13.02098202323022023","article-title":"Anti-Obesity and Anticancer Activity of Solanum Xanthocarpum Leaf Extract: An in Vitro Study","volume":"13","author":"Brattiya","year":"2023","journal-title":"Natl. J. Physiol. Pharm. Pharmacol."},{"key":"ref_182","doi-asserted-by":"crossref","unstructured":"Jaradat, N., and Hawash, M. (2021). Anti-Obesity Activities of Rumex Rothschildianus Aarons. Extracts. BMC Complement. Med. Ther., 21.","DOI":"10.1186\/s12906-021-03282-6"},{"key":"ref_183","doi-asserted-by":"crossref","first-page":"116808","DOI":"10.1016\/j.indcrop.2023.116808","article-title":"Neuroprotective Potential of Phytochemicals Isolated from Paeonia Ostii \u2018Feng Dan\u2019 Stamen","volume":"200","author":"Peng","year":"2023","journal-title":"Ind. Crops Prod."},{"key":"ref_184","doi-asserted-by":"crossref","first-page":"e34992","DOI":"10.1016\/j.heliyon.2024.e34992","article-title":"Extraction, Phytochemical Profile, and Neuroprotective Activity of Phyllanthus Emblica Fruit Extract against Sodium Valproate-Induced Postnatal Autism in BALB\/c Mice","volume":"10","author":"Gouda","year":"2024","journal-title":"Heliyon"},{"key":"ref_185","doi-asserted-by":"crossref","first-page":"118292","DOI":"10.1016\/j.jep.2024.118292","article-title":"LC-QTOF-MS\/MS Phytochemical Profiling of Tabebuia Impetiginosa (Mart. Ex DC.) Standl. Leaf and Assessment of Its Neuroprotective Potential in Rats","volume":"331","author":"Khaled","year":"2024","journal-title":"J. Ethnopharmacol."},{"key":"ref_186","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.ccell.2020.06.001","article-title":"Oxidative Stress in Cancer","volume":"38","author":"Hayes","year":"2020","journal-title":"Cancer Cell"},{"key":"ref_187","doi-asserted-by":"crossref","unstructured":"Almilaibary, A. (2024). Phyto-Therapeutics as Anti-Cancer Agents in Breast Cancer: Pathway Targeting and Mechanistic Elucidation. Saudi J. Biol. Sci., 31.","DOI":"10.1016\/j.sjbs.2024.103935"},{"key":"ref_188","doi-asserted-by":"crossref","unstructured":"Yun, C.W., Jeon, J., Go, G., Lee, J.H., and Lee, S.H. (2021). The Dual Role of Autophagy in Cancer Development and a Therapeutic Strategy for Cancer by Targeting Autophagy. Int. J. Mol. Sci., 22.","DOI":"10.3390\/ijms22010179"},{"key":"ref_189","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.jfda.2019.11.001","article-title":"Recent Advances in Cancer Chemoprevention with Phytochemicals","volume":"28","author":"Koh","year":"2020","journal-title":"J. Food Drug Anal."},{"key":"ref_190","doi-asserted-by":"crossref","unstructured":"Bastos, R.G., and de, O. (2023). Rodrigues, S.; Marques, L.A.; Oliveira, C.M. d.; Salles, B.C.C.; Zanatta, A.C.; Rocha, F.D.; Vilegas, W.; Pagnossa, J.P.; Fernanda, F.B.; et al. Eugenia Sonderiana O. Berg Leaves: Phytochemical Characterization, Evaluation of in Vitro and in Vivo Antidiabetic Effects, and Structure-Activity Correlation. Biomed. Pharmacother., 165.","DOI":"10.1016\/j.biopha.2023.115126"},{"key":"ref_191","doi-asserted-by":"crossref","first-page":"100429","DOI":"10.1016\/j.focha.2023.100429","article-title":"Volatiles, Phenolic Compounds and Bioactive Properties of Essential Oil and Aqueous Extract of Purple Basil (Ocimum basilicum L.) and Antidiabetic Activity in Streptozotocin-Induced Diabetic Wistar Rats","volume":"3","author":"Kanmaz","year":"2023","journal-title":"Food Chem. Adv."},{"key":"ref_192","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.jfda.2016.10.018","article-title":"Cellular Models for the Evaluation of the Antiobesity Effect of Selected Phytochemicals from Food and Herbs","volume":"25","author":"Tung","year":"2017","journal-title":"J. Food Drug Anal."},{"key":"ref_193","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1002\/mnfr.200500102","article-title":"Anti-Obesity Effects of Green Tea: From Bedside to Bench","volume":"50","author":"Wolfram","year":"2006","journal-title":"Mol. Nutr. Food Res."},{"key":"ref_194","doi-asserted-by":"crossref","unstructured":"Suescun, J., Chandra, S., and Schiess, M.C. (2019). The Role of Neuroinflammation in Neurodegenerative Disorders. Translational Cell Biology, Elsevier.","DOI":"10.1016\/B978-0-12-813832-8.00013-3"},{"key":"ref_195","doi-asserted-by":"crossref","first-page":"155272","DOI":"10.1016\/j.phymed.2023.155272","article-title":"Neuroprotective Potentials of Lead Phytochemicals against Alzheimer\u2019s Disease with Focus on Oxidative Stress-Mediated Signaling Pathways: Pharmacokinetic Challenges, Target Specificity, Clinical Trials and Future Perspectives","volume":"124","author":"Ayaz","year":"2024","journal-title":"Phytomedicine"},{"key":"ref_196","doi-asserted-by":"crossref","first-page":"131918","DOI":"10.1016\/j.foodchem.2021.131918","article-title":"Influence of the Extraction Method on the Recovery of Bioactive Phenolic Compounds from Food Industry By-Products","volume":"378","author":"Romero","year":"2022","journal-title":"Food Chem."},{"key":"ref_197","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.canlet.2013.02.032","article-title":"Bioavailability of Phytochemicals and Its Enhancement by Drug Delivery Systems","volume":"334","author":"Aqil","year":"2013","journal-title":"Cancer Lett."},{"key":"ref_198","doi-asserted-by":"crossref","unstructured":"Siddiqui, R.A., and Moghadasian, M.H. (2020). Nutraceuticals and Nutrition Supplements: Challenges and Opportunities. Nutrients, 12.","DOI":"10.3390\/nu12061593"},{"key":"ref_199","doi-asserted-by":"crossref","unstructured":"Xu, J. (2023). Harnessing the Power of Plants: A Green Factory for Bioactive Compounds. Life, 13.","DOI":"10.3390\/life13102041"},{"key":"ref_200","doi-asserted-by":"crossref","unstructured":"Kumar, A., Nirmal, P., Kumar, M., Jose, A., Tomer, V., Oz, E., Proestos, C., Zeng, M., Elobeid, T., and Sneha, V. (2023). Major Phytochemicals: Recent Advances in Health Benefits and Extraction Method. Molecules, 28.","DOI":"10.3390\/molecules28020887"},{"key":"ref_201","doi-asserted-by":"crossref","unstructured":"El Maaiden, E., Bouzroud, S., Nasser, B., Moustaid, K., El Mouttaqi, A., Ibourki, M., Boukcim, H., Hirich, A., Kouisni, L., and El Kharrassi, Y. (2022). A Comparative Study between Conventional and Advanced Extraction Techniques: Pharmaceutical and Cosmetic Properties of Plant Extracts. Molecules, 27.","DOI":"10.3390\/molecules27072074"},{"key":"ref_202","doi-asserted-by":"crossref","first-page":"117627","DOI":"10.1016\/j.trac.2024.117627","article-title":"Critical Analysis of Green Extraction Techniques Used for Botanicals: Trends, Priorities, and Optimization Strategies-A Review","volume":"173","author":"Cannavacciuolo","year":"2024","journal-title":"TrAC-Trends Anal. Chem."},{"key":"ref_203","doi-asserted-by":"crossref","unstructured":"Dom\u00ednguez, R., Pateiro, M., Munekata, P.E.S., McClements, D.J., and Lorenzo, J.M. (2021). Encapsulation of Bioactive Phytochemicals in Plant-Based Matrices and Application as Additives in Meat and Meat Products. Molecules, 26.","DOI":"10.3390\/molecules26133984"},{"key":"ref_204","doi-asserted-by":"crossref","unstructured":"Bommakanti, V., Ajikumar, A.P., Sivi, C.M., Prakash, G., Mundanat, A.S., Ahmad, F., Haque, S., Prieto, M.A., and Rana, S.S. (2023). An Overview of Herbal Nutraceuticals, Their Extraction, Formulation, Therapeutic Effects and Potential Toxicity. Separations, 10.","DOI":"10.3390\/separations10030177"},{"key":"ref_205","doi-asserted-by":"crossref","first-page":"115895","DOI":"10.1016\/j.trac.2020.115895","article-title":"Recent Advances in Scaling-up of Non-Conventional Extraction Techniques: Learning from Successes and Failures","volume":"127","author":"Belwal","year":"2020","journal-title":"TrAC-Trends Anal. Chem."},{"key":"ref_206","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.foodres.2018.07.014","article-title":"Essential Oils as Natural Additives to Prevent Oxidation Reactions in Meat and Meat Products: A Review","volume":"113","author":"Pateiro","year":"2018","journal-title":"Food Res. Int."},{"key":"ref_207","first-page":"e01585","article-title":"A Review of Modern and Conventional Extraction Techniques and Their Applications for Extracting Phytochemicals from Plants","volume":"19","author":"Bitwell","year":"2023","journal-title":"Sci. Afr."},{"key":"ref_208","doi-asserted-by":"crossref","unstructured":"Nicolescu, A., Babot\u0103, M., Barros, L., Rocchetti, G., Lucini, L., Tanase, C., Mocan, A., Bunea, C.I., and Cri\u0219an, G. (2023). Bioaccessibility and Bioactive Potential of Different Phytochemical Classes from Nutraceuticals and Functional Foods. Front. Nutr., 10.","DOI":"10.3389\/fnut.2023.1184535"},{"key":"ref_209","doi-asserted-by":"crossref","first-page":"6611","DOI":"10.3390\/molecules20046611","article-title":"Employing Response Surface Methodology for the Optimization of Ultrasound Assisted Extraction of Lutein and \u03b2-Carotene from Spinach","volume":"20","author":"Altemimi","year":"2015","journal-title":"Molecules"},{"key":"ref_210","doi-asserted-by":"crossref","unstructured":"Altemimi, A., Lakhssassi, N., Baharlouei, A., Watson, D.G., and Lightfoot, D.A. (2017). Phytochemicals: Extraction, Isolation, and Identification of Bioactive Compounds from Plant Extracts. Plants, 6.","DOI":"10.3390\/plants6040042"},{"key":"ref_211","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.foodchem.2004.03.023","article-title":"Role of Peroxidase in Anthocyanin Degradation in Litchi Fruit Pericarp","volume":"90","author":"Zhang","year":"2005","journal-title":"Food Chem."},{"key":"ref_212","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/S0731-7085(03)00552-1","article-title":"Commercial and Laboratory Extracts from Artichoke Leaves: Estimation of Caffeoyl Esters and Flavonoidic Compounds Content","volume":"34","author":"Mulinacci","year":"2004","journal-title":"J. Pharm. Biomed. Anal."},{"key":"ref_213","doi-asserted-by":"crossref","first-page":"103418","DOI":"10.1016\/j.jddst.2022.103418","article-title":"Nanotechnology: An Approach to Overcome Bioavailability Challenges of Nutraceuticals","volume":"72","author":"Manocha","year":"2022","journal-title":"J. Drug Deliv. Sci. Technol."},{"key":"ref_214","doi-asserted-by":"crossref","unstructured":"Zheng, B., and McClements, D.J. (2020). Formulation of More Efficacious Curcumin Delivery Systems Using Colloid Science: Enhanced Solubility, Stability, and Bioavailability. Molecules, 25.","DOI":"10.3390\/molecules25122791"},{"key":"ref_215","doi-asserted-by":"crossref","unstructured":"Agriopoulou, S., Tarapoulouzi, M., Varzakas, T., and Jafari, S.M. (2023). Application of Encapsulation Strategies for Probiotics: From Individual Loading to Co-Encapsulation. Microorganisms, 11.","DOI":"10.3390\/microorganisms11122896"},{"key":"ref_216","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/bs.afnr.2022.10.003","article-title":"Micro- and Nanoencapsulation of Natural Phytochemicals: Challenges and Recent Perspectives for the Food and Nutraceuticals Industry Applications","volume":"Volume 104","year":"2023","journal-title":"Advances in Food and Nutrition Research"},{"key":"ref_217","doi-asserted-by":"crossref","unstructured":"Alu\u2019datt, M.H., Alrosan, M., Gammoh, S., Tranchant, C.C., Alhamad, M.N., Rababah, T., Zghoul, R., Alzoubi, H., Ghatasheh, S., and Ghozlan, K. (2022). Encapsulation-Based Technologies for Bioactive Compounds and Their Application in the Food Industry: A Roadmap for Food-Derived Functional and Health-Promoting Ingredients. Food Biosci., 50.","DOI":"10.1016\/j.fbio.2022.101971"},{"key":"ref_218","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1002\/fft2.94","article-title":"Microencapsulation: An Overview on Concepts, Methods, Properties and Applications in Foods","volume":"2","author":"Choudhury","year":"2021","journal-title":"Food Front."},{"key":"ref_219","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1016\/j.foodchem.2018.07.205","article-title":"A Review of Microencapsulation Methods for Food Antioxidants: Principles, Advantages, Drawbacks and Applications","volume":"272","author":"Ozkan","year":"2019","journal-title":"Food Chem."},{"key":"ref_220","doi-asserted-by":"crossref","unstructured":"Pateiro, M., Munekata, P.E.S., Barba, F.J., and Putnik, P. (2021). Nanoencapsulation of Promising Bioactive Compounds to Improve Their Absorption, Stability, Functionality and the Appearance of the Final Food Products. Molecules, 26.","DOI":"10.3390\/molecules26061547"},{"key":"ref_221","doi-asserted-by":"crossref","unstructured":"Altemimi, A.B., Farag, H.A.M., Salih, T.H., Awlqadr, F.H., Al-Manhel, A.J.A., Vieira, I.R.S., and Conte-Junior, C.A. (2024). Application of Nanoparticles in Human Nutrition: A Review. Nutrients, 16.","DOI":"10.3390\/nu16050636"},{"key":"ref_222","doi-asserted-by":"crossref","first-page":"100910","DOI":"10.1016\/j.fochx.2023.100910","article-title":"Development of \u201cSmart Foods\u201d for Health by Nanoencapsulation: Novel Technologies and Challenges","volume":"20","author":"Singh","year":"2023","journal-title":"Food Chem. X"},{"key":"ref_223","doi-asserted-by":"crossref","unstructured":"Puttasiddaiah, R., Lakshminarayana, R., Somashekar, N.L., Gupta, V.K., Inbaraj, B.S., Usmani, Z., Raghavendra, V.B., Sridhar, K., Sharma, M., and Rennes-angers, L.I.A. (2022). Advances in Nanofabrication Technology for Nutraceuticals: New Insights and Future Trends. Bioengineered, 9.","DOI":"10.3390\/bioengineering9090478"},{"key":"ref_224","doi-asserted-by":"crossref","first-page":"108165","DOI":"10.1016\/j.foodhyd.2022.108165","article-title":"Bioaccessibility and Bioavailability of Phytochemicals: Influencing Factors, Improvements, and Evaluations","volume":"135","author":"Hu","year":"2023","journal-title":"Food Hydrocoll."},{"key":"ref_225","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.copbio.2008.03.003","article-title":"Nutrients and Phytochemicals: From Bioavailability to Bioefficacy beyond Antioxidants","volume":"19","author":"Holst","year":"2008","journal-title":"Curr. Opin. Biotechnol."},{"key":"ref_226","doi-asserted-by":"crossref","unstructured":"Rao, V. (2012). Bioavailability of Phytochemicals. Phytochemicals-A Global Perspective of Their Role in Nutrition and Health, IntechOpen.","DOI":"10.5772\/1387"},{"key":"ref_227","doi-asserted-by":"crossref","first-page":"6421","DOI":"10.1080\/10408398.2021.1901650","article-title":"Influence of Food Matrix and Food Processing on the Chemical Interaction and Bioaccessibility of Dietary Phytochemicals: A Review","volume":"62","author":"Shahidi","year":"2022","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"ref_228","doi-asserted-by":"crossref","unstructured":"Selby-Pham, S.N.B., Miller, R.B., Howell, K., Dunshea, F., and Bennett, L.E. (2017). Physicochemical Properties of Dietary Phytochemicals Can Predict Their Passive Absorption in the Human Small Intestine. Sci. Rep., 7.","DOI":"10.1038\/s41598-017-01888-w"},{"key":"ref_229","doi-asserted-by":"crossref","first-page":"2092","DOI":"10.1021\/acs.jafc.1c07198","article-title":"Technological and Biotechnological Processes To Enhance the Bioavailability of Dietary (Poly)Phenols in Humans","volume":"70","author":"Polia","year":"2022","journal-title":"J. Agric. Food Chem."},{"key":"ref_230","doi-asserted-by":"crossref","first-page":"105","DOI":"10.2174\/1872211313666190503112040","article-title":"Nutraceuticals\u2019 Novel Formulations: The Good, the Bad, the Unknown and Patents Involved","volume":"13","author":"Helal","year":"2019","journal-title":"Recent Pat. Drug Deliv. Formul."},{"key":"ref_231","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1016\/j.jff.2013.08.011","article-title":"Green Tea Extract: Chemistry, Antioxidant Properties and Food Applications\u2014A Review","volume":"5","author":"Senanayake","year":"2013","journal-title":"J. Funct. Foods"},{"key":"ref_232","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/j.foodres.2011.01.022","article-title":"Green Tea and Grape Seed Extracts\u2014Potential Applications in Food Safety and Quality","volume":"44","author":"Perumalla","year":"2011","journal-title":"Food Res. Int."},{"key":"ref_233","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.foodres.2017.11.047","article-title":"Application of Microencapsulation for the Safe Delivery of Green Tea Polyphenols in Food Systems: Review and Recent Advances","volume":"105","author":"Bora","year":"2018","journal-title":"Food Res. Int."},{"key":"ref_234","doi-asserted-by":"crossref","unstructured":"Nieto, G., Mart\u00ednez-Zamora, L., Pe\u00f1alver, R., Mar\u00edn-Iniesta, F., Taboada-Rodr\u00edguez, A., L\u00f3pez-G\u00f3mez, A., and Mart\u00ednez-Hern\u00e1ndez, G.B. (2023). Applications of Plant Bioactive Compounds as Replacers of Synthetic Additives in the Food Industry. Foods, 13.","DOI":"10.3390\/foods13010047"},{"key":"ref_235","doi-asserted-by":"crossref","unstructured":"Duizer, L.M., West, R., and Campanella, O.H. (2020). Fiber Addition to Cereal Based Foods: Effects on Sensory Properties. Food Engineering Series, Springer.","DOI":"10.1007\/978-3-030-38654-2_18"},{"key":"ref_236","doi-asserted-by":"crossref","first-page":"5957","DOI":"10.1002\/jsfa.11948","article-title":"Use of Natural Low-Methoxyl Pectin from Sunflower by-Products for the Formulation of Low-Sucrose Strawberry Jams","volume":"102","author":"Taladrid","year":"2022","journal-title":"J. Sci. Food Agric."},{"key":"ref_237","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1111\/1471-0307.12176","article-title":"The Effect of Inulin as a Fat Replacer on the Quality of Low-Fat Ice Cream","volume":"68","author":"Tiwari","year":"2015","journal-title":"Int. J. Dairy Technol."},{"key":"ref_238","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1007\/s10096-019-03721-w","article-title":"The Effects of Inulin on Gut Microbial Composition: A Systematic Review of Evidence from Human Studies","volume":"39","author":"Chapelet","year":"2020","journal-title":"Eur. J. Clin. Microbiol. Infect. Dis."},{"key":"ref_239","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.carbpol.2017.04.021","article-title":"Functionality and Nutritional Aspects of Microcrystalline Cellulose in Food","volume":"172","author":"Chen","year":"2017","journal-title":"Carbohydr. Polym."},{"key":"ref_240","doi-asserted-by":"crossref","unstructured":"Nath, P.C., Debnath, S., Sharma, M., Sridhar, K., Nayak, P.K., and Inbaraj, B.S. (2023). Recent Advances in Cellulose-Based Hydrogels: Food Applications. Foods, 12.","DOI":"10.3390\/foods12020350"},{"key":"ref_241","doi-asserted-by":"crossref","unstructured":"Onipe, O.O., Ramashia, S.E., and Jideani, A.I.O. (2021). Wheat Bran Modifications for Enhanced Nutrition and Functionality in Selected Food Products. Molecules, 26.","DOI":"10.3390\/molecules26133918"},{"key":"ref_242","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1002\/mnfr.200800053","article-title":"Carotenoids: Actual Knowledge on Food Sources, Intakes, Stability and Bioavailability and Their Protective Role in Humans","volume":"53","author":"Maiani","year":"2009","journal-title":"Mol. Nutr. Food Res."},{"key":"ref_243","doi-asserted-by":"crossref","first-page":"11409","DOI":"10.1080\/10408398.2023.2238063","article-title":"Progress on Molecular Modification and Functional Applications of Anthocyanins","volume":"64","author":"Wang","year":"2023","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"ref_244","unstructured":"Pereira, A.G., Fraga, M., Oliveira, P.G., Jimenez-Lopez, C., Louren\u00e7o-Lopes, C., Barros, L., Ferreira, I.C.F.R., Prieto, M.A., and Simal-Gandara, J. (2020). Identification, Quantification, and Method Validation of Anthocyanins. Anthocyanins: Antioxidant Properties, Sources and Health Benefits, Nova Science Publishers."},{"key":"ref_245","doi-asserted-by":"crossref","first-page":"5570","DOI":"10.1111\/1541-4337.12836","article-title":"Acylated Anthocyanins: A Review on Their Bioavailability and Effects on Postprandial Carbohydrate Metabolism and Inflammation","volume":"20","author":"Jokioja","year":"2021","journal-title":"Compr. Rev. Food Sci. Food Saf."},{"key":"ref_246","doi-asserted-by":"crossref","unstructured":"Mattioli, R., Francioso, A., Mosca, L., and Silva, P. (2020). Anthocyanins: A Comprehensive Review of Their Chemical Properties and Health Effects on Cardiovascular and Neurodegenerative Diseases. Molecules, 25.","DOI":"10.3390\/molecules25173809"},{"key":"ref_247","doi-asserted-by":"crossref","first-page":"109581","DOI":"10.1016\/j.lwt.2020.109581","article-title":"Rheological Aspects in Fabricating Pullulan-Whey Protein Isolate Emulsion Suitable for Electrospraying: Application in Improving \u03b2-Carotene Stability","volume":"129","author":"Niu","year":"2020","journal-title":"LWT"},{"key":"ref_248","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1002\/mnfr.201400484","article-title":"Betanin-A Food Colorant with Biological Activity","volume":"59","author":"Esatbeyoglu","year":"2015","journal-title":"Mol. Nutr. Food Res."},{"key":"ref_249","doi-asserted-by":"crossref","unstructured":"da Silva, D.V.T., dos Santos Bai\u00e3o, D., de Oliveira Silva, F., Alves, G., Perrone, D., Del Aguila, E.M., and Paschoalin, V.M.F. (2019). Betanin, a Natural Food Additive: Stability, Bioavailability, Antioxidant and Preservative Ability Assessments. Molecules, 24.","DOI":"10.3390\/molecules24030458"},{"key":"ref_250","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.foodres.2018.04.053","article-title":"Microencapsulation of Betanin in Monodisperse W\/O\/W Emulsions","volume":"109","author":"Pagano","year":"2018","journal-title":"Food Res. Int."},{"key":"ref_251","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.foodchem.2018.02.114","article-title":"Improvement in the Stability of Betanin by Liposomal Nanocarriers: Its Application in Gummy Candy as a Food Model","volume":"256","author":"Amjadi","year":"2018","journal-title":"Food Chem."},{"key":"ref_252","doi-asserted-by":"crossref","unstructured":"Dai, T., He, X., Xu, J., Geng, Q., Li, C., Sun, J., Liu, C., Chen, J., and He, X. (2022). Effects of Betanin on Pasting, Rheology and Retrogradation Properties of Different Starches. Foods, 11.","DOI":"10.3390\/foods11111600"},{"key":"ref_253","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1039\/C7FO01242J","article-title":"Curcumin as a Functional Food-Derived Factor: Degradation Products, Metabolites, Bioactivity, and Future Perspectives","volume":"9","author":"Tsuda","year":"2018","journal-title":"Food Funct."},{"key":"ref_254","doi-asserted-by":"crossref","first-page":"104392","DOI":"10.1016\/j.jff.2021.104392","article-title":"Health Benefits, Extraction and Development of Functional Foods with Curcuminoids","volume":"79","author":"Munekata","year":"2021","journal-title":"J. Funct. Foods"},{"key":"ref_255","doi-asserted-by":"crossref","unstructured":"Xu, X.Y., Meng, X., Li, S., Gan, R.Y., Li, Y., and Li, H.B. (2018). Bioactivity, Health Benefits, and Related Molecular Mechanisms of Curcumin: Current Progress, Challenges, and Perspectives. Nutrients, 10.","DOI":"10.3390\/nu10101553"},{"key":"ref_256","unstructured":"(2025, May 06). Life Extension. Available online: https:\/\/www.lifeextensioneurope.com\/."},{"key":"ref_257","unstructured":"(2025, May 07). To\u00fcfood. Available online: https:\/\/www.toufood.com\/."},{"key":"ref_258","unstructured":"(2025, May 07). Bluetec Colorants Ltd. Available online: https:\/\/www.bestphycocyanin.com\/."},{"key":"ref_259","doi-asserted-by":"crossref","first-page":"6884","DOI":"10.1021\/acs.jafc.1c03020","article-title":"Utilization of Nanotechnology to Improve the Application and Bioavailability of Phytochemicals Derived from Waste Streams","volume":"70","author":"McClements","year":"2022","journal-title":"J. Agric. Food Chem."},{"key":"ref_260","doi-asserted-by":"crossref","first-page":"3386","DOI":"10.1080\/10408398.2021.1988897","article-title":"Recent Advances in Utilization of Pectins in Biomedical Applications: A Review Focusing on Molecular Structure-Directing Health-Promoting Properties","volume":"63","author":"Zhang","year":"2023","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"ref_261","doi-asserted-by":"crossref","first-page":"2948","DOI":"10.1039\/D2FO01096H","article-title":"Inulin: Properties and Health Benefits","volume":"14","author":"Qin","year":"2023","journal-title":"Food Funct."},{"key":"ref_262","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1080\/10408398.2018.1558394","article-title":"Modifying Wheat Bran to Improve Its Health Benefits","volume":"60","author":"Deroover","year":"2020","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"ref_263","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.jep.2005.06.042","article-title":"Psyllium Decreased Serum Glucose and Glycosylated Hemoglobin Significantly in Diabetic Outpatients","volume":"102","author":"Ziai","year":"2005","journal-title":"J. Ethnopharmacol."},{"key":"ref_264","doi-asserted-by":"crossref","first-page":"7473","DOI":"10.1039\/D2FO00560C","article-title":"Beneficial Effects of Psyllium on the Prevention and Treatment of Cardiometabolic Diseases","volume":"13","author":"Chen","year":"2022","journal-title":"Food Funct."},{"key":"ref_265","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1016\/j.biopha.2017.09.024","article-title":"Green Tea (Camellia sinensis) and L-Theanine: Medicinal Values and Beneficial Applications in Humans\u2014A Comprehensive Review","volume":"95","author":"Saeed","year":"2017","journal-title":"Biomed. Pharmacother."},{"key":"ref_266","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.nutres.2012.05.007","article-title":"Green Tea Extract Reduces Blood Pressure, Inflammatory Biomarkers, and Oxidative Stress and Improves Parameters Associated with Insulin Resistance in Obese, Hypertensive Patients","volume":"32","author":"Bogdanski","year":"2012","journal-title":"Nutr. Res."},{"key":"ref_267","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1007\/s13197-019-04113-w","article-title":"Grape Seed Extract: Having a Potential Health Benefits","volume":"57","author":"Gupta","year":"2020","journal-title":"J. Food Sci. Technol."},{"key":"ref_268","doi-asserted-by":"crossref","first-page":"225S","DOI":"10.1093\/jn\/134.1.225S","article-title":"From 1989 to 2001: What Have We Learned about the \u201cBiological Actions of Beta-Carotene\u201d?","volume":"134","author":"Bendich","year":"2004","journal-title":"J. Nutr."},{"key":"ref_269","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1080\/10408398.2015.1030064","article-title":"Health Benefits of Anthocyanins and Molecular Mechanisms: Update from Recent Decade","volume":"57","author":"Li","year":"2017","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"ref_270","doi-asserted-by":"crossref","unstructured":"Hewlings, S.J., and Kalman, D.S. (2017). Curcumin: A Review of Its Effects on Human Health. Foods, 6.","DOI":"10.3390\/foods6100092"},{"key":"ref_271","doi-asserted-by":"crossref","unstructured":"Barber, T.M., Kabisch, S., Randeva, H.S., Pfeiffer, A.F.H., and Weickert, M.O. (2022). Implications of Resveratrol in Obesity and Insulin Resistance: A State-of-the-Art Review. Nutrients, 14.","DOI":"10.3390\/nu14142870"},{"key":"ref_272","doi-asserted-by":"crossref","unstructured":"Wang, Y., Xing, M., Cao, Q., Ji, A., Liang, H., and Song, S. (2019). Biological Activities of Fucoidan and the Factors Mediating Its Therapeutic Effects: A Review of Recent Studies. Mar. Drugs, 17.","DOI":"10.3390\/md17030183"},{"key":"ref_273","doi-asserted-by":"crossref","unstructured":"Li, F., and Liu, K. (2022). Research Progress in the Preparation, Structural Characterization, Bioactivities, and Potential Applications of Sulfated Agarans from the Genus Gracilaria. J. Food Biochem., 46.","DOI":"10.1111\/jfbc.14401"},{"key":"ref_274","doi-asserted-by":"crossref","unstructured":"du Preez, R., Paul, N., Mouatt, P., Majzoub, M.E., Thomas, T., Panchal, S.K., and Brown, L. (2020). Carrageenans from the Red Seaweed Sarconema Filiforme Attenuate Symptoms of Diet-Induced Metabolic Syndrome in Rats. Mar. Drugs, 18.","DOI":"10.3390\/md18020097"},{"key":"ref_275","doi-asserted-by":"crossref","unstructured":"and Maurya, P.K. (2022). Health Benefits of Quercetin in Age-Related Diseases. Molecules, 27.","DOI":"10.3390\/molecules27082498"},{"key":"ref_276","doi-asserted-by":"crossref","unstructured":"Aghababaei, F., and Hadidi, M. (2023). Recent Advances in Potential Health Benefits of Quercetin. Pharmaceuticals, 16.","DOI":"10.3390\/ph16071020"},{"key":"ref_277","first-page":"138","article-title":"A Review Focusing on the Benefits of Green Tea Catechins as Nutraceuticals","volume":"2","author":"Naware","year":"2023","journal-title":"Sci. Phytochem."},{"key":"ref_278","doi-asserted-by":"crossref","unstructured":"Ma, D.S.L., Tan, L.T.H., Chan, K.G., Yap, W.H., Pusparajah, P., Chuah, L.H., Ming, L.C., Khan, T.M., Lee, L.H., and Goh, B.H. (2018). Resveratrol-Potential Antibacterial Agent against Foodborne Pathogens. Front. Pharmacol., 9.","DOI":"10.3389\/fphar.2018.00102"},{"key":"ref_279","doi-asserted-by":"crossref","first-page":"103","DOI":"10.5668\/JEHS.2017.43.2.103","article-title":"Determination of Hazardous Metals in Nail Enamel Containing Glitter","volume":"43","author":"Ko","year":"2017","journal-title":"Korean J. Environ. Health Sci."},{"key":"ref_280","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1111\/bcp.12916","article-title":"A Phase I Pharmacokinetics Trial Comparing PF-05280586 (a Potential Biosimilar) and Rituximab in Patients with Active Rheumatoid Arthritis","volume":"82","author":"Cohen","year":"2016","journal-title":"Br. J. Clin. Pharmacol."},{"key":"ref_281","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/s12934-018-0879-x","article-title":"The Promising Future of Microalgae: Current Status, Challenges, and Optimization of a Sustainable and Renewable Industry for Biofuels, Feed, and Other Products","volume":"17","author":"Khan","year":"2018","journal-title":"Microb. Cell Fact."},{"key":"ref_282","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.procbio.2019.06.013","article-title":"Arginyl-Glycyl-Aspartic Acid (RGD) Containing Nanostructured Lipid Carrier Co-Loaded with Doxorubicin and Sildenafil Citrate Enhanced Anti-Cancer Effects and Overcomes Drug Resistance","volume":"84","author":"Hajipour","year":"2019","journal-title":"Process Biochem."},{"key":"ref_283","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1080\/10408398.2017.1394268","article-title":"The Oxidative Stability of Omega-3 Oil-in-Water Nanoemulsion Systems Suitable for Functional Food Enrichment: A Systematic Review of the Literature","volume":"59","author":"Bush","year":"2019","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"ref_284","doi-asserted-by":"crossref","first-page":"129800","DOI":"10.1016\/j.chemosphere.2021.129800","article-title":"Microalgae as Sustainable Food and Feed Sources for Animals and Humans\u2013Biotechnological and Environmental Aspects","volume":"271","author":"Kusmayadi","year":"2021","journal-title":"Chemosphere"},{"key":"ref_285","doi-asserted-by":"crossref","unstructured":"Stanton, A.V., James, K., Brennan, M.M., O\u2019Donovan, F., Buskandar, F., Shortall, K., El-Sayed, T., Kennedy, J., Hayes, H., and Fahey, A.G. (2020). Omega-3 Index and Blood Pressure Responses to Eating Foods Naturally Enriched with Omega-3 Polyunsaturated Fatty Acids: A Randomized Controlled Trial. Sci. Rep., 10.","DOI":"10.1038\/s41598-020-71801-5"},{"key":"ref_286","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.jff.2012.08.007","article-title":"Fucoidans as a Natural Bioactive Ingredient for Functional Foods","volume":"5","author":"Vo","year":"2013","journal-title":"J. Funct. Foods"},{"key":"ref_287","doi-asserted-by":"crossref","first-page":"18296","DOI":"10.1074\/jbc.RA118.005134","article-title":"Endo-Fucoidan Hydrolases from Glycoside Hydrolase Family 107 (GH107) Display Structural and Mechanistic Similarities to \u03b1-L-Fucosidases from GH29","volume":"293","author":"Vickers","year":"2018","journal-title":"J. Biol. Chem."},{"key":"ref_288","doi-asserted-by":"crossref","unstructured":"Wang, M., Veeraperumal, S., Zhong, S., and Cheong, K.L. (2023). Fucoidan-Derived Functional Oligosaccharides: Recent Developments, Preparation, and Potential Applications. Foods, 12.","DOI":"10.3390\/foods12040878"},{"key":"ref_289","doi-asserted-by":"crossref","unstructured":"Fernando, I.P.S., Dias, M.K.H.M., Madusanka, D.M.D., Han, E.J., Kim, M.J., Heo, S.J., and Ahn, G. (2021). Fucoidan Fractionated from Sargassum Coreanum via Step-Gradient Ethanol Precipitation Indicate Promising Uvb-Protective Effects in Human Keratinocytes. Antioxidants, 10.","DOI":"10.3390\/antiox10030347"},{"key":"ref_290","doi-asserted-by":"crossref","first-page":"118076","DOI":"10.1016\/j.carbpol.2021.118076","article-title":"Agar Oligosaccharides: A Review of Preparation, Structures, Bioactivities and Application","volume":"265","author":"Chen","year":"2021","journal-title":"Carbohydr. Polym."},{"key":"ref_291","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1016\/j.tifs.2008.08.001","article-title":"Gelatin Alternatives for the Food Industry: Recent Developments, Challenges and Prospects","volume":"19","author":"Karim","year":"2008","journal-title":"Trends Food Sci. Technol."},{"key":"ref_292","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1080\/10408399609527719","article-title":"Carrageenans and Their Use in Meat Products","volume":"36","author":"Trius","year":"1996","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"ref_293","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1080\/07388551.2018.1472550","article-title":"Insight into Carrageenases: Major Review of Sources, Category, Property, Purification Method, Structure, and Applications","volume":"38","author":"Zhu","year":"2018","journal-title":"Crit. Rev. Biotechnol."},{"key":"ref_294","doi-asserted-by":"crossref","unstructured":"Dai, Y., and Row, K.H. (2019). Application of Natural Deep Eutectic Solvents in the Extraction of Quercetin from Vegetables. Molecules, 24.","DOI":"10.3390\/molecules24122300"},{"key":"ref_295","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.jff.2017.11.018","article-title":"Role of Quercetin in the Physicochemical Properties, Antioxidant and Antiglycation Activities of Bread","volume":"40","author":"Lin","year":"2018","journal-title":"J. Funct. Foods"},{"key":"ref_296","doi-asserted-by":"crossref","unstructured":"Bhat, I.U.H., and Bhat, R. (2021). Quercetin: A Bioactive Compound Imparting Cardiovascular and Neuroprotective Benefits: Scope for Exploring Fresh Produce, Their Wastes, and by-Products. Biology, 10.","DOI":"10.3390\/biology10070586"},{"key":"ref_297","unstructured":"(2025, May 07). Ceamsa. Available online: https:\/\/www.ceamsa.com\/."},{"key":"ref_298","unstructured":"(2025, May 07). Swanson. Available online: https:\/\/swansoneurope.com\/."},{"key":"ref_299","unstructured":"(2025, May 07). Algamar Ltd. Available online: https:\/\/algamar.com\/."},{"key":"ref_300","unstructured":"(2025, May 07). Kohbo Labs. Available online: https:\/\/kobholabs.com\/."}],"container-title":["Foods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2304-8158\/14\/10\/1749\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T17:32:52Z","timestamp":1760031172000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2304-8158\/14\/10\/1749"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,14]]},"references-count":300,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2025,5]]}},"alternative-id":["foods14101749"],"URL":"https:\/\/doi.org\/10.3390\/foods14101749","relation":{},"ISSN":["2304-8158"],"issn-type":[{"value":"2304-8158","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,14]]}}}