{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T05:19:44Z","timestamp":1775452784706,"version":"3.50.1"},"reference-count":97,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2020,10,27]],"date-time":"2020-10-27T00:00:00Z","timestamp":1603756800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Geriatrics"],"abstract":"<jats:p>(1) Background: We proposed to review worldwide estimates of cognitive impairment prevalence and incidence in adults older than 50 years of age living in the community. (2) Methods: Systematic searches were performed in January 2019 using MEDLINE\/PubMed. Articles were selected if they referred to cognitive impairment, prevalence, incidence, elders, and population or community-based studies. Analysis, aggregated by different methodologic features, was performed. (3) Results: Prevalence (80 studies) ranged between 5.1% and 41% with a median of 19.0% (25th percentile = 12.0%; 75th percentile = 24.90%). Incidence (11 studies) ranged from 22 to 76.8 per 1000 person-years with a median of 53.97 per 1000 person-years (25th percentile = 39.0; 75th percentile = 68.19). No statistically significant effects were found except for inclusion age. (4) Conclusion: We propose that the homogenization and clarification of the definition of what constitutes cognitive impairment are essential to refine the epidemiological understanding of this entity. The results of this review reinforce the importance of adherence to standardized cut-off scores for cognitive tests to promote study comparability.<\/jats:p>","DOI":"10.3390\/geriatrics5040084","type":"journal-article","created":{"date-parts":[[2020,10,27]],"date-time":"2020-10-27T09:22:45Z","timestamp":1603790565000},"page":"84","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":252,"title":["Global Cognitive Impairment Prevalence and Incidence in Community Dwelling Older Adults\u2014A Systematic Review"],"prefix":"10.3390","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1931-2659","authenticated-orcid":false,"given":"Ricardo","family":"Pais","sequence":"first","affiliation":[{"name":"EPIUnit\u2014Instituto de Sa\u00fade P\u00fablica, Universidade do Porto, Rua das Taipas, n\u00b0 135, 4050-600 Porto, Portugal"},{"name":"Departamento de Epidemiologia Cl\u00ednica, Medicina Preditiva e Sa\u00fade P\u00fablica, Faculdade de Medicina da Universidade do Porto, Alameda Prof. Hern\u00e2ni Monteiro, 4200-319 Porto, Portugal"},{"name":"Unidade de Sa\u00fade Familiar Lusitana, Aces D\u00e3o Laf\u00f5es, A.R.S. Centro, Av. Ant\u00f3nio Jos\u00e9 Almeida, 3514-511 Viseu, Portugal"}]},{"given":"Lu\u00eds","family":"Ruano","sequence":"additional","affiliation":[{"name":"EPIUnit\u2014Instituto de Sa\u00fade P\u00fablica, Universidade do Porto, Rua das Taipas, n\u00b0 135, 4050-600 Porto, Portugal"},{"name":"Departamento de Epidemiologia Cl\u00ednica, Medicina Preditiva e Sa\u00fade P\u00fablica, Faculdade de Medicina da Universidade do Porto, Alameda Prof. Hern\u00e2ni Monteiro, 4200-319 Porto, Portugal"},{"name":"Departamento de Neurologia, Hospital de S\u00e3o Sebasti\u00e3o, Centro Hospitalar de Entre o Douro e Vouga, Rua C\u00e2ndido Pinho, 4520-211 Santa Maria da Feira, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7450-9980","authenticated-orcid":false,"given":"Of\u00e9lia","family":"P. Carvalho","sequence":"additional","affiliation":[{"name":"EPIUnit\u2014Instituto de Sa\u00fade P\u00fablica, Universidade do Porto, Rua das Taipas, n\u00b0 135, 4050-600 Porto, Portugal"},{"name":"Departamento de Epidemiologia Cl\u00ednica, Medicina Preditiva e Sa\u00fade P\u00fablica, Faculdade de Medicina da Universidade do Porto, Alameda Prof. Hern\u00e2ni Monteiro, 4200-319 Porto, Portugal"}]},{"given":"Henrique","family":"Barros","sequence":"additional","affiliation":[{"name":"EPIUnit\u2014Instituto de Sa\u00fade P\u00fablica, Universidade do Porto, Rua das Taipas, n\u00b0 135, 4050-600 Porto, Portugal"},{"name":"Departamento de Epidemiologia Cl\u00ednica, Medicina Preditiva e Sa\u00fade P\u00fablica, Faculdade de Medicina da Universidade do Porto, Alameda Prof. Hern\u00e2ni Monteiro, 4200-319 Porto, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2020,10,27]]},"reference":[{"key":"ref_1","unstructured":"UN (2015). 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