{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T11:32:54Z","timestamp":1777030374614,"version":"3.51.4"},"reference-count":34,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2022,6,13]],"date-time":"2022-06-13T00:00:00Z","timestamp":1655078400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Geriatrics"],"abstract":"<jats:p>Oxidative stress is defined as the imbalance between reactive species and antioxidant agents. One of the effects of oxidative stress is the normal process of cellular aging that stems from the accumulation of tissue damage. Epidemiological studies show that regular physical exercise prevents the injuries caused by aging. The objective was to evaluate whether the practice of hydrotherapy, in an elderly population, positively influenced the activity of the enzymes superoxide dismutase, glutathione peroxidase and reductase that act by reducing reactive species in the body. The study involved 37 participants aged \u2265 60 years, of both sexes, divided into experimental and control groups. The experimental group performed 15 hydrotherapy sessions. Enzyme activity was evaluated in two moments: T0-before the first session, and T1-after the last session, with blood collections conducted in both. In T1, there was a significant increase vs. T0 of glutathione peroxidase activity (57.72 \u00b1 19.99 vs. 48.14 \u00b1 17.22 U\/g Hb) and glutathione reductase activity (100.18 \u00b1 30.85 vs. 78.44 \u00b1 21.26 U\/L). Both sexes tended to show higher values at T1. We concluded that hydrotherapy proved to be a positive stimulus for the enzymatic antioxidant activity of the elderly, suggesting that a regular and moderate practice of physical exercise induces better and higher quality of life.<\/jats:p>","DOI":"10.3390\/geriatrics7030064","type":"journal-article","created":{"date-parts":[[2022,6,13]],"date-time":"2022-06-13T06:31:59Z","timestamp":1655101919000},"page":"64","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Impact of Hydrotherapy on Antioxidant Enzyme Activity in an Elderly Population"],"prefix":"10.3390","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0157-6648","authenticated-orcid":false,"given":"Ana","family":"Valado","sequence":"first","affiliation":[{"name":"Biomedical Laboratory Sciences, Coimbra Health School, Polytechnic Institute of Coimbra, Rua 5 de Outubro\u2014SM Bispo, Apartado 7006, 3045-043 Coimbra, Portugal"},{"name":"Laboratory for Applied Health Research (LabinSa\u00fade), Rua 5 de Outubro-SM Bispo, Apartado 7006, 3046-854 Coimbra, Portugal"},{"name":"Marine and Environmental Sciences Centre (MARE), Faculty of Sciences and Technology, University of Coimbra, 3001-456 Coimbra, Portugal"}]},{"given":"Stephanie","family":"Fortes","sequence":"additional","affiliation":[{"name":"Biomedical Laboratory Sciences, Coimbra Health School, Polytechnic Institute of Coimbra, Rua 5 de Outubro\u2014SM Bispo, Apartado 7006, 3045-043 Coimbra, Portugal"}]},{"given":"M\u00e1rcia","family":"Morais","sequence":"additional","affiliation":[{"name":"Biomedical Laboratory Sciences, Coimbra Health School, Polytechnic Institute of Coimbra, Rua 5 de Outubro\u2014SM Bispo, Apartado 7006, 3045-043 Coimbra, Portugal"}]},{"given":"Rog\u00e9rio","family":"Barreira","sequence":"additional","affiliation":[{"name":"Biomedical Laboratory Sciences, Coimbra Health School, Polytechnic Institute of Coimbra, Rua 5 de Outubro\u2014SM Bispo, Apartado 7006, 3045-043 Coimbra, Portugal"},{"name":"Centro Hospitalar e Universit\u00e1rio de Coimbra, Servi\u00e7o de Sangue e Medicina Transfusional, Praceta Prof. Mota Pinto, 3000-075 Coimbra, Portugal"}]},{"given":"Jo\u00e3o Paulo","family":"Figueiredo","sequence":"additional","affiliation":[{"name":"Complementary Sciences, Coimbra Health School, Polytechnic Institute of Coimbra, Rua 5 de Outubro\u2014SM Bispo, Apartado 7006, 3045-043 Coimbra, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7844-0506","authenticated-orcid":false,"given":"Armando","family":"Caseiro","sequence":"additional","affiliation":[{"name":"Biomedical Laboratory Sciences, Coimbra Health School, Polytechnic Institute of Coimbra, Rua 5 de Outubro\u2014SM Bispo, Apartado 7006, 3045-043 Coimbra, Portugal"},{"name":"Laboratory for Applied Health Research (LabinSa\u00fade), Rua 5 de Outubro-SM Bispo, Apartado 7006, 3046-854 Coimbra, Portugal"},{"name":"Unidade I&D Qu\u00edmica-F\u00edsica Molecular, Faculdade de Ci\u00eancias e Tecnologia, Universidade de Coimbra, 3030-790 Coimbra, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2022,6,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.ejmech.2015.04.040","article-title":"The role of antioxidants in the chemistry of oxidative stress: A review","volume":"97","author":"Pisoschi","year":"2015","journal-title":"Eur. 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