{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T04:44:35Z","timestamp":1762058675330,"version":"build-2065373602"},"reference-count":80,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2022,7,7]],"date-time":"2022-07-07T00:00:00Z","timestamp":1657152000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Swiss National Science Foundation","award":["51NF40-185901","10001C_189407","UIDB\/50009\/2020"],"award-info":[{"award-number":["51NF40-185901","10001C_189407","UIDB\/50009\/2020"]}]},{"name":"LARSyS\u2014Portuguese national funding agency for science, research and technology (FCT) pluriannual funding 2020\u20132023","award":["51NF40-185901","10001C_189407","UIDB\/50009\/2020"],"award-info":[{"award-number":["51NF40-185901","10001C_189407","UIDB\/50009\/2020"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Geriatrics"],"abstract":"<jats:p>Introduction: With vulnerable aging, gait speed (GS) undergoes progressive changes, becoming slower. In this process, cognitive performance (CP) and physical function (PF) both play an important role. This study aims (1) to investigate the association between CP and PF with GS and (2) to examine whether CP and PF mediate the association between age and GS in a large sample of Brazilian older adults. Methods: A cross-sectional study analyzed 697 individuals (mean age 70.35 \u00b1 6.86 years) from the state of Amazonas. The CP was evaluated by the COGTEL test battery, PF by the Senior Fitness Test battery, and GS with the 50-foot Walk Test. Results: Older adults with a lower CP and PF had a 70% and 86% chance of slow GS, respectively. When CP and PF were placed simultaneously as mediators, the direct effect estimated by the model revealed a non-significant relationship between age and GS. Specifically, CP and PF mediated the association between age and GS, at approximately 12% and 98%, respectively. Conclusions: CP and PF show the potential to estimate GS performance among older adults. Moreover, CP and PF indicated a negative and direct association between age and slow GS, especially PF.<\/jats:p>","DOI":"10.3390\/geriatrics7040073","type":"journal-article","created":{"date-parts":[[2022,7,7]],"date-time":"2022-07-07T07:51:56Z","timestamp":1657180316000},"page":"73","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The Role of Cognitive Performance and Physical Functions in the Association between Age and Gait Speed: A Mediation Study"],"prefix":"10.3390","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3577-3439","authenticated-orcid":false,"given":"Marcelo de Maio","family":"Nascimento","sequence":"first","affiliation":[{"name":"Department of Physical Education, Federal University of Vale do S\u00e3o Francisco, Petrolina 56304-917, Brazil"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0927-692X","authenticated-orcid":false,"given":"\u00c9lvio R\u00fabio","family":"Gouveia","sequence":"additional","affiliation":[{"name":"Department of Physical Education and Sport, University of Madeira, 9020-105 Funchal, Portugal"},{"name":"LARSYS-Laboratory for Robotics and Engineering System, Interactive Technologies Institute, 9020-105 Funchal, Portugal"},{"name":"Center for the Interdisciplinary Study of Gerontology and Vulnerability, University of Geneva, 1205 Geneva, Switzerland"}]},{"given":"Bruna R.","family":"Gouveia","sequence":"additional","affiliation":[{"name":"LARSYS-Laboratory for Robotics and Engineering System, Interactive Technologies Institute, 9020-105 Funchal, Portugal"},{"name":"Center for the Interdisciplinary Study of Gerontology and Vulnerability, University of Geneva, 1205 Geneva, Switzerland"},{"name":"Regional Directorate of Health, Secretary of Health of the Autonomous Region of Madeira, 9004-515 Funchal, Portugal"},{"name":"Saint Joseph of Cluny Higher School of Nursing, 9050-535 Funchal, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9850-7771","authenticated-orcid":false,"given":"Adilson","family":"Marques","sequence":"additional","affiliation":[{"name":"CIPER-Interdisciplinary Centre for the Study of Human Performance Faculty of Human Kinetics, University of Lisbon, 1495-751 Lisbon, Portugal"},{"name":"ISAMB-Environmental Health Institute, Faculty of Medicine, University of Lisbon, 1649-020 Lisbon, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1295-0826","authenticated-orcid":false,"given":"Priscila","family":"Marconcin","sequence":"additional","affiliation":[{"name":"CIPER-Interdisciplinary Centre for the Study of Human Performance Faculty of Human Kinetics, University of Lisbon, 1495-751 Lisbon, Portugal"},{"name":"KinesioLab, Research Unit in Human Movement Analysis, Piaget Institute, 2805-059 Almada, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8364-6832","authenticated-orcid":false,"given":"C\u00edntia","family":"Fran\u00e7a","sequence":"additional","affiliation":[{"name":"Department of Physical Education and Sport, University of Madeira, 9020-105 Funchal, Portugal"},{"name":"LARSYS-Laboratory for Robotics and Engineering System, Interactive Technologies Institute, 9020-105 Funchal, Portugal"}]},{"given":"Andreas","family":"Ihle","sequence":"additional","affiliation":[{"name":"Center for the Interdisciplinary Study of Gerontology and Vulnerability, University of Geneva, 1205 Geneva, Switzerland"},{"name":"Department of Psychology, University of Geneva, 1205 Geneva, Switzerland"},{"name":"Swiss National Centre of Competence in Research LIVES\u2014Overcoming Vulnerability: Life Course Perspectives, 1015 Lausanne, Switzerland"}]}],"member":"1968","published-online":{"date-parts":[[2022,7,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1123\/japa.12.1.90","article-title":"Relationship between Balance and Gait Stability in Healthy Older Adults","volume":"12","author":"Cromwell","year":"2004","journal-title":"J. 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