{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T09:29:37Z","timestamp":1773480577171,"version":"3.50.1"},"reference-count":62,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2023,5,8]],"date-time":"2023-05-08T00:00:00Z","timestamp":1683504000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Healthcare"],"abstract":"<jats:p>Patients with kidney failure (KF) receiving maintenance hemodialysis (HD) experience numerous symptoms that impair their health-related quality of life (HRQOL) and contribute to high mortality rates. Acupuncture is often used for symptom enhancement and HRQOL. This blinded, randomized, controlled patient-assessor trial evaluated the effectiveness of acupuncture compared with sham acupuncture on patients\u2019 HRQOL receiving maintenance HD as a secondary analysis. Seventy-two participants were randomly assigned to verum acupuncture (VA), sham acupuncture (SA), or waiting-list (WL) groups. The outcome was an improvement in HRQOL, assessed using the Kidney Disease Quality of Life\u2014Short Form, version 1.3 (KDQOL-SF\u2122 v1.3) at baseline, after treatment, and at 12-week follow-up. Non-parametric tests were used for statistical analysis. Of the 72 randomized patients, 67 were included in the complete analysis set. As for the changes between baseline and after treatment, the VA group showed significantly increased scores on most of the KDQOL-SF\u2122 v1.3 scales compared to SA or WL groups (p &lt; 0.05). No statistically significant differences between groups were observed in the changes from baseline to follow-up (p &gt; 0.05). Compared to the sham treatment, acupuncture improved the HRQOL in patients receiving maintenance HD after treatment but not at follow-up.<\/jats:p>","DOI":"10.3390\/healthcare11091355","type":"journal-article","created":{"date-parts":[[2023,5,9]],"date-time":"2023-05-09T01:06:28Z","timestamp":1683594388000},"page":"1355","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Effectiveness of Acupuncture on Health-Related Quality of Life in Patients Receiving Maintenance Hemodialysis"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5624-3306","authenticated-orcid":false,"given":"Marta","family":"Correia de Carvalho","sequence":"first","affiliation":[{"name":"ICBAS, School of Medicine and Biomedical Sciences, University of Porto, 4050-313 Porto, Portugal"}]},{"given":"Jos\u00e9","family":"Nunes de Azevedo","sequence":"additional","affiliation":[{"name":"TECSAM-Tecnologia e Servi\u00e7os M\u00e9dicos SA, 5370-530 Mirandela, Portugal"}]},{"given":"Pedro","family":"Azevedo","sequence":"additional","affiliation":[{"name":"TECSAM-Tecnologia e Servi\u00e7os M\u00e9dicos SA, 5370-530 Mirandela, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9190-1119","authenticated-orcid":false,"given":"Carlos","family":"Pires","sequence":"additional","affiliation":[{"name":"Center for Research in Neuropsychology and Cognitive and Behavioral Intervention (CINEICC), Faculty of Psychology and Educational Sciences, University of Coimbra, 3000-115 Coimbra, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4570-5445","authenticated-orcid":false,"given":"Jorge Pereira","family":"Machado","sequence":"additional","affiliation":[{"name":"ICBAS, School of Medicine and Biomedical Sciences, University of Porto, 4050-313 Porto, Portugal"},{"name":"CBSin, Center of BioSciences in Integrative Health, 4000-105 Porto, Portugal"}]},{"given":"Manuel","family":"Laranjeira","sequence":"additional","affiliation":[{"name":"ICBAS, School of Medicine and Biomedical Sciences, University of Porto, 4050-313 Porto, Portugal"},{"name":"INC, Instituto de Neuroci\u00eancias, 4100-141 Porto, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2023,5,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.semnephrol.2016.05.008","article-title":"The Economic Burden of Chronic Kidney Disease and End-Stage Renal Disease","volume":"36","author":"Wang","year":"2016","journal-title":"Semin. 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