{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T03:34:38Z","timestamp":1760240078121,"version":"build-2065373602"},"reference-count":91,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2019,2,5]],"date-time":"2019-02-05T00:00:00Z","timestamp":1549324800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005635","name":"Funda\u00e7\u00e3o Calouste Gulbenkian","doi-asserted-by":"publisher","award":["NA"],"award-info":[{"award-number":["NA"]}],"id":[{"id":"10.13039\/501100005635","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Angola reports one of the highest infant mortality rates in the world, and anemia represents one of its important causes. Recent studies, in under-five children from the Bengo province of Angola, described high prevalence\u2019s, suggesting malaria, undernutrition and urogenital schistosomiasis as important contributors for the occurrence and spatial variations of anemia. Educational community-based interventions, either in Nutrition and Water, Sanitation, Hygiene and Malaria are recommended to correct anemia. Herein, we designed a cluster-randomized controlled trial to study the efficacy of two educational-plus-therapeutic interventions in the reduction of anemia: one in nutrition and the other in WASH\/Malaria. Socioeconomic, nutritional, anthropometric, parasitological and biochemical data will be collected from all willing-to-participate children, aging under four and resident in the Health Research Center of Angola study area. Considering the multifactorial causes of this condition, determining the efficacy of both interventions might help documenting weaknesses and opportunities for planning integrated strategies to reduce anemia.<\/jats:p>","DOI":"10.3390\/ijerph16030466","type":"journal-article","created":{"date-parts":[[2019,2,6]],"date-time":"2019-02-06T03:03:05Z","timestamp":1549422185000},"page":"466","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Efficacy of Nutrition and WASH\/Malaria Educational Community-Based Interventions in Reducing Anemia in Preschool Children from Bengo, Angola: Study Protocol of a Randomized Controlled Trial"],"prefix":"10.3390","volume":"16","author":[{"given":"Cl\u00e1udia","family":"Fan\u00e7ony","sequence":"first","affiliation":[{"name":"Health Research Center of Angola (CISA), Caxito, Esta\u00e7\u00e3o Central de Luanda, Apartado IV n\u00b05547, Luanda, Angola"},{"name":"Institute of Public Health, University of Porto, 4050-091 Porto, Portugal"}]},{"given":"\u00c2nia","family":"Soares","sequence":"additional","affiliation":[{"name":"Health Research Center of Angola (CISA), Caxito, Esta\u00e7\u00e3o Central de Luanda, Apartado IV n\u00b05547, Luanda, Angola"}]},{"given":"Jo\u00e3o","family":"Lavinha","sequence":"additional","affiliation":[{"name":"Department of Human Genetics, National Health Institute Doctor Ricardo Jorge, 1649-016 Lisbon, Portugal"},{"name":"BioISI, Faculty of Science, University of Lisbon, 1749-016 Lisbon, Portugal"}]},{"given":"Henrique","family":"Barros","sequence":"additional","affiliation":[{"name":"Institute of Public Health, University of Porto, 4050-091 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6394-658X","authenticated-orcid":false,"given":"Miguel","family":"Brito","sequence":"additional","affiliation":[{"name":"Health Research Center of Angola (CISA), Caxito, Esta\u00e7\u00e3o Central de Luanda, Apartado IV n\u00b05547, Luanda, Angola"},{"name":"Health and Technology Research Center, Escola Superior de Tecniologia da Sa\u00fade de Lisboa, Instituto Polit\u00e9cnico de Lisboa, 1990-096 Lisbon, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2019,2,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"636S","DOI":"10.1093\/jn\/131.2.636S","article-title":"An analysis of anemia and child mortality","volume":"131","author":"Brabin","year":"2001","journal-title":"J. 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