{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T10:56:07Z","timestamp":1771671367170,"version":"3.50.1"},"reference-count":44,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2020,9,22]],"date-time":"2020-09-22T00:00:00Z","timestamp":1600732800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Air quality and other environmental factors are gaining importance in public health policies. Some volatile organic compounds (VOCs) have been associated with asthma and symptoms of respiratory disease such as wheezing. The aim of this study was to measure the concentration of Total VOCs and assess their possible association with the occurrence of wheezing episodes in children under 36 months of age, in a region south of Lisbon, Portugal. A cross-sectional study was performed from October 2015 to March 2016. The sample of children under 36 months of age was selected by convenience, by inviting parents to take part in the study. A survey was applied to collect information on bedroom features, as well as to verify the occurrence of wheezing episodes. The indoor air quality parameters of bedrooms were measured using three 3M Quest\u00ae EVM-7 environmental monitors. In total, 34.4% of infants had had wheezing episodes since birth, with 86.7% of these presenting at least one episode in the previous 12 months. Total VOC levels were above the reference values in 48% of the analyzed bedrooms. No significant association of VOC exposure in a domestic setting with episodes of wheezing was found. However, children living in households with smokers were 4 times more likely to develop wheezing episodes. Thus, this study provides relevant information that warrants further studies to assess infant exposure to indoor air pollution and parental smoking in a residential context.<\/jats:p>","DOI":"10.3390\/ijerph17186929","type":"journal-article","created":{"date-parts":[[2020,9,22]],"date-time":"2020-09-22T09:40:56Z","timestamp":1600767656000},"page":"6929","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Exploring Volatile Organic Compound Exposure and Its Association with Wheezing in Children under 36 Months: A Cross-Sectional Study in South Lisbon, Portugal"],"prefix":"10.3390","volume":"17","author":[{"given":"Raquel","family":"Rodrigues dos Santos","sequence":"first","affiliation":[{"name":"CBIOS\u2014Research Center for Biosciences and Health Technologies, Universidade Lus\u00f3fona de Humanidades e Tecnologias, Campo Grande, 376, 1749-024 Lisboa, Portugal"},{"name":"Administra\u00e7\u00e3o Regional de Sa\u00fade de Lisboa e Vale do Tejo, I.P. Agrupamento de Centros de Sa\u00fade do Arco Ribeirinho, Unidade Sa\u00fade de Sa\u00fade P\u00fablica Arnaldo Sampaio, 2835-423 Lavradio, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6130-9453","authenticated-orcid":false,"given":"Jo\u00e3o","family":"Greg\u00f3rio","sequence":"additional","affiliation":[{"name":"CBIOS\u2014Research Center for Biosciences and Health Technologies, Universidade Lus\u00f3fona de Humanidades e Tecnologias, Campo Grande, 376, 1749-024 Lisboa, Portugal"}]},{"given":"Liliana","family":"Castanheira","sequence":"additional","affiliation":[{"name":"CBIOS\u2014Research Center for Biosciences and Health Technologies, Universidade Lus\u00f3fona de Humanidades e Tecnologias, Campo Grande, 376, 1749-024 Lisboa, Portugal"},{"name":"Administra\u00e7\u00e3o Regional de Sa\u00fade de Lisboa e Vale do Tejo, I.P., Unidade Sa\u00fade Familiar do Dafundo, 1495-713 Dafundo, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6350-0641","authenticated-orcid":false,"given":"Ana S.","family":"Fernandes","sequence":"additional","affiliation":[{"name":"CBIOS\u2014Research Center for Biosciences and Health Technologies, Universidade Lus\u00f3fona de Humanidades e Tecnologias, Campo Grande, 376, 1749-024 Lisboa, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2020,9,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2029","DOI":"10.1016\/S0140-6736(18)30667-6","article-title":"Investing in non-communicable disease prevention and management to advance the Sustainable Development Goals","volume":"391","author":"Nugent","year":"2018","journal-title":"Lancet"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1183\/09059180.00000714","article-title":"Volatile organic compounds and risk of asthma and allergy: A systematic review","volume":"24","author":"Nurmatov","year":"2015","journal-title":"Eur. 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