{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T13:56:29Z","timestamp":1778680589595,"version":"3.51.4"},"reference-count":33,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2021,2,2]],"date-time":"2021-02-02T00:00:00Z","timestamp":1612224000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001871","name":"FCT","doi-asserted-by":"publisher","award":["UIDB\/04585\/2020"],"award-info":[{"award-number":["UIDB\/04585\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>The aim of this study was to develop and validate a predictive early tooth loss multivariable model for periodontitis patients before periodontal treatment. A total of 544 patients seeking periodontal care at the university dental hospital were enrolled in the study. Teeth extracted after periodontal diagnosis and due to periodontal reasons were recorded. Clinical and sociodemographic variables were analyzed, considering the risk of short-term tooth loss. This study followed the transparent reporting of a multivariable prediction model for individual prognosis or diagnosis (TRIPOD) guidelines for development and validation, with two cohorts considered as follows: 455 patients in the development phase and 99 in the validation phase. As a result, it was possible to compute a predictive model based on tooth type and clinical attachment loss. The model explained 25.3% of the total variability and correctly ranked 98.9% of the cases. The final reduced model area under the curve (AUC) was 0.809 (95% confidence interval (95% CI): 0.629\u20130.989) for the validation sample and 0.920 (95% CI: 0.891\u20130.950) for the development cohort. The established model presented adequate prediction potential of early tooth loss due to periodontitis. This model may have clinical and epidemiologic relevance towards the prediction of tooth loss burden.<\/jats:p>","DOI":"10.3390\/ijerph18031363","type":"journal-article","created":{"date-parts":[[2021,2,2]],"date-time":"2021-02-02T20:52:01Z","timestamp":1612299121000},"page":"1363","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Early Tooth Loss after Periodontal Diagnosis: Development and Validation of a Clinical Decision Model"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2387-6729","authenticated-orcid":false,"given":"Francisco","family":"Santos","sequence":"first","affiliation":[{"name":"Clinical Research Unit (CRU), Centro de Investiga\u00e7\u00e3o Interdisciplinar Egas Moniz (CiiEM), Egas Moniz\u2014Cooperativa de Ensino Superior, CRL, 2829-511 Almada, Portugal"}]},{"given":"Frederico","family":"Beato","sequence":"additional","affiliation":[{"name":"Clinical Research Unit (CRU), Centro de Investiga\u00e7\u00e3o Interdisciplinar Egas Moniz (CiiEM), Egas Moniz\u2014Cooperativa de Ensino Superior, CRL, 2829-511 Almada, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2503-260X","authenticated-orcid":false,"given":"Vanessa","family":"Machado","sequence":"additional","affiliation":[{"name":"Clinical Research Unit (CRU), Centro de Investiga\u00e7\u00e3o Interdisciplinar Egas Moniz (CiiEM), Egas Moniz\u2014Cooperativa de Ensino Superior, CRL, 2829-511 Almada, Portugal"},{"name":"Department of Periodontology, CRU, CiiEM, Egas Moniz\u2014Cooperativa de Ensino Superior, CRL, 2829-511 Almada, Portugal"},{"name":"Evidence-Based Hub, CRU, CiiEM, Egas Moniz\u2014Cooperativa de Ensino Superior, CRL, 2829-511 Almada, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8482-5936","authenticated-orcid":false,"given":"Lu\u00eds","family":"Proen\u00e7a","sequence":"additional","affiliation":[{"name":"Evidence-Based Hub, CRU, CiiEM, Egas Moniz\u2014Cooperativa de Ensino Superior, CRL, 2829-511 Almada, Portugal"},{"name":"Quantitative Methods for Health Research (MQIS), CiiEM, Egas Moniz\u2014Cooperativa de Ensino Superior, CRL, 2829-511 Almada, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0167-4077","authenticated-orcid":false,"given":"Jos\u00e9 Jo\u00e3o","family":"Mendes","sequence":"additional","affiliation":[{"name":"Clinical Research Unit (CRU), Centro de Investiga\u00e7\u00e3o Interdisciplinar Egas Moniz (CiiEM), Egas Moniz\u2014Cooperativa de Ensino Superior, CRL, 2829-511 Almada, Portugal"},{"name":"Evidence-Based Hub, CRU, CiiEM, Egas Moniz\u2014Cooperativa de Ensino Superior, CRL, 2829-511 Almada, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1019-8263","authenticated-orcid":false,"given":"Jo\u00e3o","family":"Botelho","sequence":"additional","affiliation":[{"name":"Clinical Research Unit (CRU), Centro de Investiga\u00e7\u00e3o Interdisciplinar Egas Moniz (CiiEM), Egas Moniz\u2014Cooperativa de Ensino Superior, CRL, 2829-511 Almada, Portugal"},{"name":"Department of Periodontology, CRU, CiiEM, Egas Moniz\u2014Cooperativa de Ensino Superior, CRL, 2829-511 Almada, Portugal"},{"name":"Evidence-Based Hub, CRU, CiiEM, Egas Moniz\u2014Cooperativa de Ensino Superior, CRL, 2829-511 Almada, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2021,2,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"S162","DOI":"10.1111\/jcpe.12946","article-title":"Periodontitis: Consensus report of workgroup 2 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions","volume":"45","author":"Papapanou","year":"2018","journal-title":"J. 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