{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T18:40:19Z","timestamp":1778006419407,"version":"3.51.4"},"reference-count":80,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2021,5,21]],"date-time":"2021-05-21T00:00:00Z","timestamp":1621555200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Portuguese Foundation of Science and Technology FCT","award":["CICECO-Aveiro Institute of Materials, UIDB\/50011\/2020 and UIDP\/50011\/2020"],"award-info":[{"award-number":["CICECO-Aveiro Institute of Materials, UIDB\/50011\/2020 and UIDP\/50011\/2020"]}]},{"name":"Portuguese Foundation of Science and Technology FCT","award":["FCT Ref. UID\/GEO\/04035\/2021"],"award-info":[{"award-number":["FCT Ref. UID\/GEO\/04035\/2021"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Copper chrome arsenate (CCA) water-borne solution used to be widely used to make timber highly resistant to pests and fungi, in particular, wood products designed for outdoor use. Nowadays, CCA is a restricted chemical product in most countries, since potential environmental and health risks were reported due to dermal contact with CCA residues from treated structures and the surrounding soil, as well as the contamination of soils. However, large quantities of CCA-treated timber are still in use in framings, outdoor playground equipment, landscaping, building poles, jetty piles, and fencing structures around the world, thus CCA remains a source of pollutants to the environment and of increasing toxic metal\/metalloid exposure (mainly in children). International efforts have been dedicated to the treatment of materials impregnated with CCA, however not only does some reuse of CCA-treated timber still occur, but also existing structures are leaking the toxic compounds into the environment, with impacts on the environment and animal and human health. This study highlights CCA mechanisms and the documented consequences in vivo of its exposure, as well as the adverse environmental and health impacts.<\/jats:p>","DOI":"10.3390\/ijerph18115518","type":"journal-article","created":{"date-parts":[[2021,5,21]],"date-time":"2021-05-21T13:15:15Z","timestamp":1621602915000},"page":"5518","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":59,"title":["Environmental and Health Hazards of Chromated Copper Arsenate-Treated Wood: A Review"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6433-5801","authenticated-orcid":false,"given":"Simone","family":"Morais","sequence":"first","affiliation":[{"name":"REQUIMTE\u2013LAQV, Instituto Superior de Engenharia do Porto, Instituto Polit\u00e9cnico do Porto, R. Dr. Ant\u00f3nio Bernardino de Almeida 431, 4200-072 Porto, Portugal"}]},{"given":"Henrique M. A. C.","family":"Fonseca","sequence":"additional","affiliation":[{"name":"GeoBioTec &amp; Department of Biology, University of Aveiro, 3810-193 Aveiro, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0707-5203","authenticated-orcid":false,"given":"S\u00f3nia M. R.","family":"Oliveira","sequence":"additional","affiliation":[{"name":"CICECO\u2014Aveiro Institute of Materials, University of Aveiro, 3810-193 Aveiro, Portugal"},{"name":"Hunter Medical Research Institute, New Lambton, NSW 2305, Australia"}]},{"given":"Helena","family":"Oliveira","sequence":"additional","affiliation":[{"name":"CESAM &amp; Department of Biology, University of Aveiro, 3810-193 Aveiro, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2847-7244","authenticated-orcid":false,"given":"Vivek Kumar","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Faculty of Science, University of Allahabad, Allahabad 211002, India"}]},{"given":"Bechan","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Faculty of Science, University of Allahabad, Allahabad 211002, India"}]},{"given":"Maria","family":"de Lourdes Pereira","sequence":"additional","affiliation":[{"name":"CICECO\u2014Aveiro Institute of Materials, University of Aveiro, 3810-193 Aveiro, Portugal"},{"name":"Department of Medical Sciences, University of Aveiro, 3810-193 Aveiro, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2021,5,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.ijwd.2016.01.002","article-title":"Chromated Copper Arsenate\u2013Treated Wood: A Potential Source of Arsenic Exposure and Toxicity in Dermatology","volume":"2","author":"Chen","year":"2016","journal-title":"Int. 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