{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T14:56:09Z","timestamp":1770994569445,"version":"3.50.1"},"reference-count":50,"publisher":"MDPI AG","issue":"24","license":[{"start":{"date-parts":[[2021,12,9]],"date-time":"2021-12-09T00:00:00Z","timestamp":1639008000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Caring for people with COVID-19 on the front line has psychological impacts for healthcare professionals. Despite the important psychological impacts of the pandemic on nurses, the qualitative evidence on this topic has not been synthesized. Our objective: To analyze and synthesize qualitative studies that investigate the perceptions of nurses about the psychological impacts of treating hospitalized people with COVID-19 on the front line. A systematic review of qualitative studies published in English or Spanish up to March 2021 was carried out in the following databases: The Cochrane Library, Medline (Pubmed), PsycINFO, Web of Science (WOS), Scopus, and CINHAL. The PRISMA statement and the Cochrane recommendations for qualitative evidence synthesis were followed. Results: The main psychological impacts of caring for people with COVID-19 perceived by nurses working on the front line were fear, anxiety, stress, social isolation, depressive symptoms, uncertainty, and frustration. The fear of infecting family members or being infected was the main repercussion perceived by the nurses. Other negative impacts that this review added and that nurses suffer as the COVID-19 pandemic progress were anger, obsessive thoughts, compulsivity, introversion, apprehension, impotence, alteration of space-time perception, somatization, and feeling of betrayal. Resilience was a coping tool used by nurses. Conclusions: Front line care for people with COVID-19 causes fear, anxiety, stress, social isolation, depressive symptoms, uncertainty, frustration, anger, obsessive thoughts, compulsivity, introversion, apprehension, impotence, alteration of space-time perception, somatization, and feeling of betrayal in nurses. It is necessary to provide front line nurses with the necessary support to reduce the psychological impact derived from caring for people with COVID-19, improve training programs for future pandemics, and analyze the long-term impacts.<\/jats:p>","DOI":"10.3390\/ijerph182412975","type":"journal-article","created":{"date-parts":[[2021,12,9]],"date-time":"2021-12-09T21:46:58Z","timestamp":1639086418000},"page":"12975","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":51,"title":["The Psychological Impact of COVID-19 on Front Line Nurses: A Synthesis of Qualitative Evidence"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4276-1038","authenticated-orcid":false,"given":"Sara","family":"Huerta-Gonz\u00e1lez","sequence":"first","affiliation":[{"name":"Faculty of Nursing, Universidad Veracruzana, Tuxpan, Poza Rica 91000, Mexico"}]},{"given":"Dolores","family":"Selva-Medrano","sequence":"additional","affiliation":[{"name":"Health Service of Castilla-La Mancha, University Hospital Complex of Albacete, C. Hermanos Falco, 37, 02006 Albacete, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7509-1192","authenticated-orcid":false,"given":"Fidel","family":"L\u00f3pez-Espuela","sequence":"additional","affiliation":[{"name":"Metabolic Bone Diseases Research Group, Department of Nursing, Faculty of Nursing and Occupational Therapy, University of Extremadura, 10004 Caceres, Spain"}]},{"given":"Pedro \u00c1ngel","family":"Caro-Alonso","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, University of Castilla-La Mancha, Avd\/Real F\u00e1brica de Sedas s\/n, 45660 Talavera de la Reina, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8583-0406","authenticated-orcid":false,"given":"Andre","family":"Novo","sequence":"additional","affiliation":[{"name":"Instituto Polit\u00e9cnico de Bragan\u00e7a, 5300-253 Bragan\u00e7a, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3939-0299","authenticated-orcid":false,"given":"Beatriz","family":"Rodr\u00edguez-Mart\u00edn","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, University of Castilla-La Mancha, Avd\/Real F\u00e1brica de Sedas s\/n, 45660 Talavera de la Reina, Spain"}]}],"member":"1968","published-online":{"date-parts":[[2021,12,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.ijid.2020.02.058","article-title":"A conceptual model for the coronavirus disease 2019 (COVID-19) outbreak in Wuhan, China with individual reaction and governmental action","volume":"93","author":"Lin","year":"2020","journal-title":"Int. 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