{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T03:33:32Z","timestamp":1775100812362,"version":"3.50.1"},"reference-count":127,"publisher":"MDPI AG","issue":"24","license":[{"start":{"date-parts":[[2021,12,18]],"date-time":"2021-12-18T00:00:00Z","timestamp":1639785600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Anterior cruciate ligament (ACL) is one of the most concerning injuries for football players. The aim of this review is to investigate the effects of exercise-based interventions targeting at reducing ACL injury rate or mitigating risk factors of ACL injury in adult football players. Following PRISMA guidelines, a systematic search was conducted in CINAHL, Cochrane Library, PubMed, Scopus, SPORTDiscus and Web of Science. Studies assessing the effect of exercise-based interventions in ACL injury incidence or modifiable risk factors in adult football players were included. 29 studies evaluating 4502 male and 1589 female players were included (15 RCT, 8 NRCT, 6 single-arm): 14 included warm-up, 7 resistance training, 4 mixed training, 3 balance, 1 core stability and 1 technique modification interventions. 6 out of 29 studies investigated the effect of interventions on ACL injury incidence, while the remaining 23 investigated their effect on risk factors. Only 21% and 13% studies evaluating risk of injury variables reported reliability measures and\/or smallest worthwhile change data. Warm-up, core stability, balance and technique modification appear effective and feasible interventions to be included in football teams. However, the use of more ecologically valid tests and individually tailored interventions targeting specific ACL injury mechanisms are required.<\/jats:p>","DOI":"10.3390\/ijerph182413351","type":"journal-article","created":{"date-parts":[[2021,12,19]],"date-time":"2021-12-19T20:37:27Z","timestamp":1639946247000},"page":"13351","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["Exercise-Based Training Strategies to Reduce the Incidence or Mitigate the Risk Factors of Anterior Cruciate Ligament Injury in Adult Football (Soccer) Players: A Systematic Review"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4748-4578","authenticated-orcid":false,"given":"Jes\u00fas","family":"Olivares-Jabalera","sequence":"first","affiliation":[{"name":"HUMAN Lab, Sport and Health University Research Institute (iMUDS), University of Granada, 18016 Granada, Spain"},{"name":"FSI Sport Research Lab, 18016 Granada, Spain"}]},{"given":"Alberto","family":"F\u00edlter-Ruger","sequence":"additional","affiliation":[{"name":"FSI Sport Research Lab, 18016 Granada, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2715-0116","authenticated-orcid":false,"given":"Thomas","family":"Dos\u2019Santos","sequence":"additional","affiliation":[{"name":"FSI Sport Research Lab, 18016 Granada, Spain"},{"name":"Department of Sport and Exercise Sciences, Musculoskeletal Science and Sports Medicine Research Centre, All Saints Building, Manchester Campus John Dalton Building, Manchester Campus, Manchester Metropolitan University, Manchester M15 6BH, UK"},{"name":"Manchester Institute of Sport 2.01, Manchester Metropolitan University, Manchester M1 7EL, UK"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2038-393X","authenticated-orcid":false,"given":"Jose","family":"Afonso","sequence":"additional","affiliation":[{"name":"Centre for Research, Education, Innovation and Intervention in Sport, Faculty of Sports of the University of Porto, Rua Dr. Pl\u00e1cido Costa, 91, 4200-450 Porto, Portugal"}]},{"given":"Francesco","family":"Della Villa","sequence":"additional","affiliation":[{"name":"Education and Research Department, Isokinetic Medical Group, FIFA Medical Centre of Excellence, 40132 Bologna, Italy"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8142-6083","authenticated-orcid":false,"given":"Jaime","family":"Morente-S\u00e1nchez","sequence":"additional","affiliation":[{"name":"FSI Sport Research Lab, 18016 Granada, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0213-5844","authenticated-orcid":false,"given":"V\u00edctor Manuel","family":"Soto-Hermoso","sequence":"additional","affiliation":[{"name":"HUMAN Lab, Sport and Health University Research Institute (iMUDS), University of Granada, 18016 Granada, Spain"}]},{"given":"Bernardo","family":"Requena","sequence":"additional","affiliation":[{"name":"HUMAN Lab, Sport and Health University Research Institute (iMUDS), University of Granada, 18016 Granada, Spain"},{"name":"FSI Sport Research Lab, 18016 Granada, Spain"}]}],"member":"1968","published-online":{"date-parts":[[2021,12,18]]},"reference":[{"key":"ref_1","unstructured":"F\u00e9d\u00e9ration Internationale de Football Association (FIFA) (2007). FIFA Big Count 2006: 270 Million People Active in Football. FIFA Commun. Div. Inf. Serv., 31, 1\u201312."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1136\/bjsports-2020-103159","article-title":"Injury rates decreased in men\u2019s professional football: An 18-year prospective cohort study of almost 12 000 injuries sustained during 1.8 million hours of play","volume":"55","author":"Ekstrand","year":"2021","journal-title":"Br. J. Sports Med."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1136\/bjsports-2016-096731","article-title":"Injuries impair the chance of successful performance by sportspeople: A systematic review","volume":"51","author":"Drew","year":"2017","journal-title":"Br. J. Sports Med."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1136\/bjsports-2012-091040","article-title":"Low injury rate strongly correlates with team success in Qatari professional football","volume":"47","author":"Eirale","year":"2013","journal-title":"Br. J. Sports Med."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1136\/bjsports-2013-092215","article-title":"Injuries affect team performance negatively in professional football: An 11-year follow-up of the UEFA Champions League injury study","volume":"47","author":"Magnusson","year":"2013","journal-title":"Br. J. Sports Med."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"e000675","DOI":"10.1136\/bmjsem-2019-000675","article-title":"Estimation of injury costs: Financial damage of English Premier League teams\u2019 underachievement due to injuries","volume":"6","author":"Eliakim","year":"2020","journal-title":"BMJ Open Sport Exerc. Med."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"2201","DOI":"10.1177\/0363546509350301","article-title":"Knee Function and Prevalence of Knee Osteoarthritis after Anterior Cruciate Ligament Reconstruction: A Prospective Study with 10 to 15 Years of Follow-Up","volume":"38","author":"Holm","year":"2010","journal-title":"Am. J. Sports Med."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1177\/2325967120934751","article-title":"Clinical Outcomes After Anterior Cruciate Ligament Injury: Panther Symposium ACL Injury Clinical Outcomes Consensus Group","volume":"8","author":"Svantesson","year":"2020","journal-title":"Orthop. J. Sports Med."},{"key":"ref_9","first-page":"31","article-title":"Female Soccer Players with Anterior Cruciate Ligament Reconstruction Have a Higher Risk of New Knee Injuries and Quit Soccer to a Higher Degree Than Knee-Healthy Controls","volume":"47","author":"Kvist","year":"2018","journal-title":"Am. J. Sports Med."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.1177\/0363546514524164","article-title":"Anterior Cruciate Ligament Injury, Return to Play, and Reinjury in the Elite Collegiate Athlete: Analysis of an NCAA Division I Cohort","volume":"42","author":"Kamath","year":"2014","journal-title":"Am. J. Sports Med."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.arthro.2019.05.052","article-title":"High Risk of Further Anterior Cruciate Ligament Injury in a 10-Year Follow-up Study of Anterior Cruciate Ligament-Reconstructed Soccer Players in the Swedish National Knee Ligament Registry","volume":"36","author":"Sandon","year":"2020","journal-title":"Arthrosc. J. Arthrosc. Relat. Surg."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1177\/2325967119883867","article-title":"Trends in Recurrent Anterior Cruciate Ligament Injuries Differ From New Anterior Cruciate Ligament Injuries in College and High School Sports: 2009-2010 through 2016\u20132017","volume":"7","author":"Slater","year":"2019","journal-title":"Orthop. J. Sports Med."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1007\/s40279-020-01404-7","article-title":"Return to Sport and Reinjury Rates in Elite Female Athletes after Anterior Cruciate Ligament Rupture","volume":"51","author":"Webster","year":"2021","journal-title":"Sports Med."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1136\/bjsports-2020-103555","article-title":"High rate of second ACL injury following ACL reconstruction in male professional footballers: An updated longitudinal analysis from 118 players in the UEFA Elite Club Injury Study","volume":"55","author":"Ekstrand","year":"2021","journal-title":"Br. J. Sports Med."},{"key":"ref_15","first-page":"1","article-title":"Injury and illness epidemiology in professional Asian football: Lower general incidence and burden but higher ACL and hamstring injury burden compared with Europe","volume":"2020","author":"Tabben","year":"2021","journal-title":"Br. J. Sports Med."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1136\/bjsports-2013-092394","article-title":"Fewer ligament injuries but no preventive effect on muscle injuries and severe injuries: An 11-year follow-up of the UEFA Champions League injury study","volume":"47","author":"Ekstrand","year":"2013","journal-title":"Br. J. Sports Med."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1136\/bjsports-2015-095952","article-title":"ACL injuries in men\u2019s professional football: A 15-year prospective study on time trends and return-to-play rates reveals only 65% of players still play at the top level 3 years after ACL rupture","volume":"50","author":"Magnusson","year":"2016","journal-title":"Br. J. Sports Med."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1136\/bjsports-2019-101247","article-title":"Systematic video analysis of ACL injuries in professional male football (soccer): Injury mechanisms, situational patterns and biomechanics study on 134 consecutive cases","volume":"54","author":"Buckthorpe","year":"2020","journal-title":"Br. J. Sports Med."},{"key":"ref_19","first-page":"1724","article-title":"Anterior cruciate ligament injury risk factors in football","volume":"59","author":"Bisciotti","year":"2019","journal-title":"J. Sports Med. Phys. Fit."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1177\/1941738119885642","article-title":"Epidemiology of Anterior Cruciate Ligament Injury in Italian First Division Soccer Players","volume":"12","author":"Grassi","year":"2019","journal-title":"Sports Health"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"2049","DOI":"10.1177\/0363546514556737","article-title":"Anterior Cruciate Ligament and Knee Injury Prevention Programs for Soccer Players: A Systematic Review and Meta-Analysis","volume":"43","author":"Grimm","year":"2015","journal-title":"Am. J. Sports Med."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1136\/bjsports-2016-096256","article-title":"Why screening tests to predict injury do not work\u2014and probably never will\u2026: A critical review","volume":"50","author":"Bahr","year":"2016","journal-title":"Br. J. Sports Med."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1007\/s00167-009-0813-1","article-title":"Prevention of non-contact anterior cruciate ligament injuries in soccer players. Part 1: Mechanisms of injury and underlying risk factors","volume":"17","author":"Myer","year":"2009","journal-title":"Knee Surg. Sport Traumatol. Arthrosc."},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"International Olympic Committee Injury and Illness Epidemiology Consensus Group, Bahr, R., Clarsen, B., Derman, W., Dvorak, J., Emery, C.A., Finch, C.F., H\u00e4gglund, M., Junge, A., and Kemp, S. (2020). International Olympic Committee Consensus Statement: Methods for Recording and Reporting of Epidemiological Data on Injury and Illness in Sports 2020 (Including the STROBE Extension for Sports Injury and Illness Surveillance (STROBE-SIIS)). Orthop. J. Sports Med., 8, 1\u201333.","DOI":"10.1177\/2325967120984266"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1093\/jpepsy\/jsp036","article-title":"Assessing Injuries with Proxies: Implications for Understanding Concurrent Relations and Behavioral Antecedents of Pediatric Injuries","volume":"35","author":"Karazsia","year":"2009","journal-title":"J. Pediatr. Psychol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1136\/bjsports-2016-096760","article-title":"Predicting sport and occupational lower extremity injury risk through movement quality screening: A systematic review","volume":"51","author":"Whittaker","year":"2017","journal-title":"Br. J. Sports Med."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1177\/0363546505284183","article-title":"Anterior Cruciate Ligament Injuries in Female Athletes: Part 1, Mechanisms and Risk Factors","volume":"34","author":"Hewett","year":"2006","journal-title":"Am. J. Sports Med."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1794","DOI":"10.1177\/03635465211008169","article-title":"Systematic Video Analysis of Anterior Cruciate Ligament Injuries in Professional Female Soccer Players","volume":"49","author":"Lucarno","year":"2021","journal-title":"Am. J. Sports Med."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1136\/bjsports-2014-094573","article-title":"Three distinct mechanisms predominate in non-contact anterior cruciate ligament injuries in male professional football players: A systematic video analysis of 39 cases","volume":"49","author":"Krosshaug","year":"2015","journal-title":"Br. J. Sports Med."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1007\/s40279-018-0968-3","article-title":"The Effect of Angle and Velocity on Change of Direction Biomechanics: An Angle-Velocity Trade-Off","volume":"48","author":"Thomas","year":"2018","journal-title":"Sports Med."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.1007\/s40279-018-0931-3","article-title":"Change-of-Direction Biomechanics: Is What\u2019s Best for Anterior Cruciate Ligament Injury Prevention Also Best for Performance?","volume":"48","author":"Fox","year":"2018","journal-title":"Sports Med."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s40798-019-0185-0","article-title":"Alternative Methods of Determining Hamstrings-to-Quadriceps Ratios: A Comprehensive Review","volume":"5","author":"Ruas","year":"2019","journal-title":"Sports Med. Open"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1016\/S0021-9290(01)00095-1","article-title":"Strategies of muscular support of varus and valgus isometric loads at the human knee","volume":"34","author":"Lloyd","year":"2001","journal-title":"J. Biomech."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1016\/j.arthro.2017.08.302","article-title":"Is There an Association Between Noncontact Anterior Cruciate Ligament Injuries and Decreased Hip Internal Rotation or Radiographic Femoroacetabular Impingement? A Systematic Review","volume":"34","author":"Boutris","year":"2018","journal-title":"Arthrosc. J. Arthrosc. Relat. Surg."},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Howe, L.P., Bampouras, T.M., North, J.S., and Waldron, M. (2020). Improved Ankle Mobility After a 4-Week Training Program Affects Landing Mechanics. J. Strength Cond. Res., 1\u20139.","DOI":"10.1519\/JSC.0000000000003717"},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Monajati, A., Larumbe-Zabala, E., Goss-Sampson, M., and Naclerio, F. (2016). The Effectiveness of Injury Prevention Programs to Modify Risk Factors for Non-Contact Anterior Cruciate Ligament and Hamstring Injuries in Uninjured Team Sports Athletes: A Systematic Review. PLoS ONE, 11.","DOI":"10.1371\/journal.pone.0155272"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"1492","DOI":"10.1177\/0363546517716930","article-title":"The Effects of Injury Prevention Programs on the Biomechanics of Landing Tasks: A Systematic Review with Meta-analysis","volume":"46","author":"Lopes","year":"2018","journal-title":"Am. J. Sports Med."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1177\/1941738111430203","article-title":"Anterior Cruciate Ligament Injury Prevention Training in Female Athletes: A Systematic Review of Injury Reduction and Results of Athletic Performance Tests","volume":"4","author":"Noyes","year":"2012","journal-title":"Sports Health"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1177\/0363546514523388","article-title":"Assessing the Effectiveness of Neuromuscular Training Programs in Reducing the Incidence of Anterior Cruciate Ligament Injuries in Female Athletes: A Systematic Review","volume":"43","author":"Stevenson","year":"2014","journal-title":"Am. J. Sports Med."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1080\/15438627.2012.680988","article-title":"Preventing ACL Injuries in Team-Sport Athletes: A Systematic Review of Training Interventions","volume":"20","author":"Stojanovic","year":"2012","journal-title":"Res. Sports Med."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1136\/bjsports-2013-092358","article-title":"Evaluation of the effectiveness of anterior cruciate ligament injury prevention programme training components: A systematic review and meta-analysis","volume":"49","author":"Taylor","year":"2015","journal-title":"Br. J. Sports Med."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1007\/s40279-020-01282-z","article-title":"Exercise-Based Strategies to Prevent Muscle Injury in Elite Footballers: A Systematic Review and Best Evidence Synthesis","volume":"50","author":"Fanchini","year":"2020","journal-title":"Sports Med."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1111\/sms.13681","article-title":"Elite football of 2030 will not be the same as that of 2020: Preparing players, coaches, and support staff for the evolution","volume":"30","author":"Nassis","year":"2020","journal-title":"Scand. J. Med. Sci. Sports"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1007\/s40279-015-0443-3","article-title":"A Systematic Evaluation of Field-Based Screening Methods for the Assessment of Anterior Cruciate Ligament (ACL) Injury Risk","volume":"46","author":"Fox","year":"2016","journal-title":"Sports Med."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"e100009","DOI":"10.1371\/journal.pmed.1000097","article-title":"Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement","volume":"6","author":"Moher","year":"2009","journal-title":"PLoS Med."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1007\/s00167-013-2739-x","article-title":"Prevention of non-contact anterior cruciate ligament injuries in sports. Part II: Systematic review of the effectiveness of prevention programmes in male athletes","volume":"22","author":"Samuelsson","year":"2014","journal-title":"Knee Surg. Sport Traumatol. Arthrosc."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1519\/SSC.0000000000000613","article-title":"Assessing Group-Based Changes in High-Performance Sport. Part 2: Effect Sizes and Embracing Uncertainty through Confidence Intervals","volume":"43","author":"Turner","year":"2021","journal-title":"Strength Cond. J."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1249\/MSS.0b013e31818cb278","article-title":"Progressive Statistics for Studies in Sports Medicine and Exercise Science","volume":"41","author":"Hopkins","year":"2009","journal-title":"Med. Sci. Sports Exerc."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"l4898","DOI":"10.1136\/bmj.l4898","article-title":"RoB 2: A revised tool for assessing risk of bias in randomised trials","volume":"366","author":"Sterne","year":"2019","journal-title":"BMJ"},{"key":"ref_50","first-page":"i4919","article-title":"ROBINS-I: A tool for assessing risk of bias in non-randomised studies of interventions","volume":"355","author":"Sterne","year":"2016","journal-title":"BMJ Clin. Res. Ed."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"d5928","DOI":"10.1136\/bmj.d5928","article-title":"The Cochrane Collaboration\u2019s tool for assessing risk of bias in randomised trials","volume":"343","author":"Higgins","year":"2011","journal-title":"BMJ"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"14","DOI":"10.2478\/pjst-2019-0009","article-title":"Three-Week Intensive Neuromuscular Training Improves Postural Control in Professional Male Soccer Players","volume":"26","author":"Kowalczyk","year":"2019","journal-title":"Pol. J. Sport Tour."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1177\/0363546508318188","article-title":"A Randomized Controlled Trial to Prevent Noncontact Anterior Cruciate Ligament Injury in Female Collegiate Soccer Players","volume":"36","author":"Gilchrist","year":"2008","journal-title":"Am. J. Sports Med."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"782","DOI":"10.4085\/1062-6050-48.4.08","article-title":"Soccer-Specific Warm-Up and Lower Extremity Injury Rates in Collegiate Male Soccer Players","volume":"48","author":"Grooms","year":"2013","journal-title":"J. Athl. Train."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1007\/s00167-019-05706-w","article-title":"Prevention of severe knee injuries in men\u2019s elite football by implementing specific training modules","volume":"28","author":"Krutsch","year":"2019","journal-title":"Knee Surg. Sports Traumatol. Arthrosc."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"2628","DOI":"10.1177\/0363546515602009","article-title":"Efficacy of the FIFA 11+ Injury Prevention Program in the Collegiate Male Soccer Player","volume":"43","author":"Mandelbaum","year":"2015","journal-title":"Am. J. Sports Med."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"2447","DOI":"10.1007\/s11999-017-5342-5","article-title":"Does the FIFA 11+ Injury Prevention Program Reduce the Incidence of ACL Injury in Male Soccer Players?","volume":"475","author":"Bizzini","year":"2017","journal-title":"Clin. Orthop. Relat. Res."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1111\/sms.13532","article-title":"Rescheduling Part 2 of the 11+ reduces injury burden and increases compliance in semi-professional football","volume":"29","author":"Whalan","year":"2019","journal-title":"Scand. J. Med. Sci. Sports"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"2592","DOI":"10.1111\/sms.13278","article-title":"Changes in biomechanical knee injury risk factors across two collegiate soccer seasons using the 11+ prevention program","volume":"28","author":"Arundale","year":"2018","journal-title":"Scand. J. Med. Sci. Sports"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1055\/s-0042-121260","article-title":"Training Effects of the FIFA 11+ and Harmoknee on Several Neuromuscular Parameters of Physical Performance Measures","volume":"38","author":"Ayala","year":"2017","journal-title":"Int. J. Sports Med."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"211","DOI":"10.3233\/IES-2010-0386","article-title":"Isokinetic strength effects of FIFA\u2019s \u201cThe 11+\u201d injury prevention training programme","volume":"18","author":"Brito","year":"2010","journal-title":"Isokinet. Exerc. Sci."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.ptsp.2009.12.002","article-title":"Effects of eccentric exercise on optimum length of the knee flexors and extensors during the preseason in professional soccer players","volume":"11","author":"Brughelli","year":"2010","journal-title":"Phys. Ther. Sport"},{"key":"ref_63","doi-asserted-by":"crossref","unstructured":"Daneshjoo, A., Mokhtar, A.H., Rahnama, N., and Yusof, A. (2012). The Effects of Comprehensive Warm-Up Programs on Proprioception, Static and Dynamic Balance on Male Soccer Players. PLoS ONE, 7.","DOI":"10.1371\/journal.pone.0051568"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fphys.2018.01059","article-title":"Strength-Endurance Training Reduces the Hamstrings Strength Decline Following Simulated Football Competition in Female Players","volume":"9","author":"Delextrat","year":"2018","journal-title":"Front. Physiol."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1080\/02640414.2015.1068437","article-title":"Core stability training on lower limb balance strength","volume":"34","author":"Padulo","year":"2016","journal-title":"J. Sports Sci."},{"key":"ref_66","doi-asserted-by":"crossref","unstructured":"Dos\u2019Santos, T., McBurnie, A., Comfort, P., and Jones, P.A. (2019). The Effects of Six-Weeks Change of Direction Speed and Technique Modification Training on Cutting Performance and Movement Quality in Male Youth Soccer Players. Sports, 7.","DOI":"10.3390\/sports7090205"},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1007\/s11332-008-0047-5","article-title":"Isokinetic strength training program for muscular imbalances in professional soccer players","volume":"2","author":"Gioftsidou","year":"2008","journal-title":"Sport Sci. Health"},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"639","DOI":"10.4100\/jhse.2012.73.04","article-title":"Balance training programs for soccer injuries prevention","volume":"7","author":"Gioftsidou","year":"2012","journal-title":"J. Hum. Sport Exerc."},{"key":"ref_69","first-page":"617","article-title":"Comparaci\u00f3n de un entrenamiento propioceptivo sobre base estable y base inestable \/ Comparison of a Proprioceptive Training Program on Stable Base and Unstable Base","volume":"64","author":"Boza","year":"2016","journal-title":"Rev. Int. Med. Cienc. Act. F\u00edsica Deporte"},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1519\/JSC.0b013e318234ebfb","article-title":"A Feedback Inclusive Neuromuscular Training Program Alters Frontal Plane Kinematics","volume":"26","author":"Greska","year":"2012","journal-title":"J. Strength Cond. Res."},{"key":"ref_71","first-page":"41","article-title":"Effect of hamstring-emphasized resistance training on hamstring","volume":"21","author":"Holcomb","year":"2007","journal-title":"J. Strength Cond. Res."},{"key":"ref_72","first-page":"183","article-title":"Does individual-specific strength training have an effect upon knee muscle strength balances? Knee muscle strength balances","volume":"18","author":"Iri","year":"2016","journal-title":"J. Musculoskelet. Neuronal Interact."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1080\/02640414.2013.802926","article-title":"Physiological and performance responses to the FIFA 11+ (part 2): A randomised controlled trial on the training effects","volume":"31","author":"Impellizzeri","year":"2013","journal-title":"J. Sports Sci."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"27","DOI":"10.2174\/1875399X01710010027","article-title":"Changes in Isokinetic Muscle Strength in Adolescent Soccer Players after 10 Weeks of Pre-Season Training","volume":"10","author":"Lehnert","year":"2017","journal-title":"Open Sports Sci. J."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"101","DOI":"10.3233\/BMR-2004-173-403","article-title":"Proprioceptive training (balance exercises) reduces lower extremity injuries in young soccer players","volume":"17","author":"Malliou","year":"2004","journal-title":"J. Back Musculoskelet. Rehabil."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1123\/ijatt.16.4.16","article-title":"Neuromuscular Changes Following an Injury Prevention Program for ACL Injuries","volume":"16","author":"McCann","year":"2011","journal-title":"Int. J. Athl. Ther. Train."},{"key":"ref_77","first-page":"1","article-title":"Comparison of muscle activity, strength, and balance, before and after a 6-month training using the FIFA11+ program (part 2)","volume":"28","author":"Oshima","year":"2019","journal-title":"J. Orthop. Surg."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"229","DOI":"10.5114\/biolsport.2018.74636","article-title":"Effect of the 11+ injury prevention programme on fundamental movement patterns in soccer players","volume":"35","author":"Rey","year":"2018","journal-title":"Biol. Sport"},{"key":"ref_79","doi-asserted-by":"crossref","unstructured":"\u015aliwowski, R., Jadczak, \u0141., Hejna, R., and Wieczorek, A. (2015). The Effects of Individualized Resistance Strength Programs on Knee Muscular Imbalances in Junior Elite Soccer Players. PLoS ONE, 10.","DOI":"10.1371\/journal.pone.0144021"},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1111\/j.1600-0838.2007.00708.x","article-title":"Performance aspects of an injury prevention program: A ten-week intervention in adolescent female football players","volume":"18","author":"Steffen","year":"2008","journal-title":"Scand. J. Med. Sci. Sports"},{"key":"ref_81","first-page":"1976","article-title":"The effectiveness of eight weeks of a movement-based program on functional movement patterns in male professional soccer players","volume":"19","author":"Riela","year":"2019","journal-title":"J. Phys. Educ. Sport"},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1136\/bjsports-2011-090895","article-title":"Evaluation of the effectiveness of neuromuscular training to reduce anterior cruciate ligament injury in female athletes: A critical review of relative risk reduction and numbers-needed-to-treat analyses","volume":"46","author":"Sugimoto","year":"2012","journal-title":"Br. J. Sports Med."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1111\/j.1742-7843.2006.pto_412.x","article-title":"Number-Needed-to-Treat (NNT)\u2014Needs Treatment with Care","volume":"99","author":"Christensen","year":"2006","journal-title":"Basic Clin. Pharmacol. Toxicol."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13102-017-0083-z","article-title":"The FIFA 11+ injury prevention program for soccer players: A systematic review","volume":"9","author":"Sadigursky","year":"2017","journal-title":"BMC Sports Sci. Med. Rehabil."},{"key":"ref_85","first-page":"1337","article-title":"The use and modification of injury prevention exercises by professional youth soccer teams","volume":"27","author":"Young","year":"2016","journal-title":"Scand. J. Med. Sci. Sports"},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1136\/bjsports-2012-092124","article-title":"Implementation of the FIFA 11+ football warm up program: How to approach and convince the Football associations to invest in prevention","volume":"47","author":"Bizzini","year":"2013","journal-title":"Br. J. Sports Med."},{"key":"ref_87","doi-asserted-by":"crossref","unstructured":"Arundale, A.J.H., Silvers-Granelli, H.J., and Myklebust, G. (2021). ACL injury prevention: Where have we come from and where are we going?. J. Orthop. Res.","DOI":"10.1002\/jor.25058"},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"A1","DOI":"10.2519\/jospt.2018.0303","article-title":"Exercise-Based Knee and Anterior Cruciate Ligament Injury Prevention","volume":"48","author":"Arundale","year":"2018","journal-title":"J. Orthop. Sports Phys. Ther."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"1837","DOI":"10.1007\/s40279-019-01171-0","article-title":"The Effect of Training Interventions on Change of Direction Biomechanics Associated with Increased Anterior Cruciate Ligament Loading: A Scoping Review","volume":"49","author":"Thomas","year":"2019","journal-title":"Sports Med."},{"key":"ref_90","first-page":"226","article-title":"The Effectiveness of Resistance Training Using Unstable Surfaces and Devices for Rehabilitation","volume":"7","author":"Behm","year":"2012","journal-title":"Int. J. Sports Phys. Ther."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1007\/s40279-015-0384-x","article-title":"Effects of Strength Training Using Unstable Surfaces on Strength, Power and Balance Performance Across the Lifespan: A Systematic Review and Meta-analysis","volume":"45","author":"Behm","year":"2015","journal-title":"Sports Med."},{"key":"ref_92","first-page":"1","article-title":"Implementing strength training strategies for injury prevention in soccer: Sci-entific rationale and methodological recommendations","volume":"16","author":"Beato","year":"2020","journal-title":"Int. J. Sports Physiol. Perform."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1136\/bjsports-2018-099078","article-title":"Strength training as superior, dose-dependent and safe prevention of acute and overuse sports injuries: A systematic review, qualitative analysis and meta-analysis","volume":"52","author":"Lauersen","year":"2018","journal-title":"Br. J. Sports Med."},{"key":"ref_94","doi-asserted-by":"crossref","unstructured":"Benjaminse, A., and Verhagen, E. (2021). Implementing ACL Injury Prevention in Daily Sports Practice\u2014It\u2019s Not Just the Program: Let\u2019s Build Together, Involve the Context, and Improve the Content. Sports Med., 1\u20137.","DOI":"10.1007\/s40279-021-01560-4"},{"key":"ref_95","doi-asserted-by":"crossref","unstructured":"Dischiavi, S.L., A Wright, A., Heller, R.A., Love, C.E., Salzman, A.J., Harris, C.A., and Bleakley, C.M. (2021). Do ACL Injury Risk Reduction Exercises Reflect Common Injury Mechanisms? A Scoping Review of Injury Prevention Programs. Sports Health Multidiscip. Approach.","DOI":"10.1177\/19417381211037966"},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s00167-013-2725-3","article-title":"Prevention of anterior cruciate ligament injuries in sports\u2014Part I: Systematic review of risk factors in male athletes","volume":"22","author":"Samuelsson","year":"2014","journal-title":"Knee Surg. Sports Traumatol. Arthrosc."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"1512","DOI":"10.1177\/0363546506286866","article-title":"Understanding and Preventing Noncontact Anterior Cruciate Ligament Injuries: A Review of the Hunt Valley II Meeting, January 2005","volume":"34","author":"Griffin","year":"2006","journal-title":"Am. J. Sports Med."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"313","DOI":"10.2165\/00007256-200029050-00003","article-title":"Neuromuscular and Hormonal Factors Associated with Knee Injuries in Female Athletes: Strategies for Intervention","volume":"29","author":"Hewett","year":"2000","journal-title":"Sports Med."},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/s00402-017-2809-5","article-title":"Evidence-based concepts for prevention of knee and ACL injuries. 2017 guidelines of the ligament committee of the German Knee Society (DKG)","volume":"138","author":"Mehl","year":"2017","journal-title":"Arch. Orthop. Trauma Surg."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1007\/s00402-018-2984-z","article-title":"Poor static balance is a risk factor for non-contact anterior cruciate ligament injury","volume":"138","author":"Oshima","year":"2018","journal-title":"Arch. Orthop. Trauma Surg."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"42","DOI":"10.2519\/jospt.2010.3337","article-title":"The Influence of Abnormal Hip Mechanics on Knee Injury: A Biomechanical Perspective","volume":"40","author":"Powers","year":"2010","journal-title":"J. Orthop. Sports Phys. Ther."},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1136\/bjsm.37.5.384","article-title":"Risk factors for sports injuries\u2014A methodological approach","volume":"37","author":"Bahr","year":"2003","journal-title":"Br. J. Sports Med."},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1177\/0363546504269591","article-title":"Biomechanical Measures of Neuromuscular Control and Valgus Loading of the Knee Predict Anterior Cruciate Ligament Injury Risk in Female Athletes: A Prospective Study","volume":"33","author":"Hewett","year":"2005","journal-title":"Am. J. Sports Med."},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1136\/bjsm.2009.059162","article-title":"Video analysis of trunk and knee motion during non-contact anterior cruciate ligament injury in female athletes: Lateral trunk and knee abduction motion are combined components of the injury mechanism","volume":"43","author":"Hewett","year":"2009","journal-title":"Br. J. Sports Med."},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1136\/bjsports-2016-096938","article-title":"Do Functional Movement Screen (FMS) composite scores predict subsequent injury? A systematic review with meta-analysis","volume":"51","author":"Moran","year":"2017","journal-title":"Br. J. Sports Med."},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1177\/1941738111428281","article-title":"Risk Factors for Anterior Cruciate Ligament Injury","volume":"4","author":"Smith","year":"2011","journal-title":"Sports Health Multidiscip. Approach"},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1177\/0363546518756328","article-title":"Video Analysis of Anterior Cruciate Ligament Tears in Professional American Football Athletes","volume":"46","author":"Johnston","year":"2018","journal-title":"Am. J. Sports Med."},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1177\/0363546520985283","article-title":"Can Biomechanical Testing After Anterior Cruciate Ligament Reconstruction Identify Athletes at Risk for Subsequent ACL Injury to the Contralateral Uninjured Limb?","volume":"49","author":"King","year":"2021","journal-title":"Am. J. Sports Med."},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.ptsp.2019.05.004","article-title":"A qualitative screening tool to identify athletes with \u2018high-risk\u2019 movement mechanics during cutting: The cutting movement assessment score (CMAS)","volume":"38","author":"McBurnie","year":"2019","journal-title":"Phys. Ther. Sport"},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"1996","DOI":"10.1177\/0363546509343200","article-title":"The Landing Error Scoring System (LESS) Is a Valid and Reliable Clinical Assessment Tool of Jump-Landing Biomechanics: The JUMP-ACL study","volume":"37","author":"Padua","year":"2009","journal-title":"Am. J. Sports Med."},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.ptsp.2012.05.005","article-title":"Intra and inter-tester reliability of the tuck jump assessment","volume":"14","author":"Herrington","year":"2013","journal-title":"Phys. Ther. Sport"},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"2","DOI":"10.7243\/2055-2386-1-2","article-title":"A preliminary reliability study of a qualitative scoring system of limb alignment during single leg squat","volume":"1","author":"Almangoush","year":"2014","journal-title":"Phys. Ther. Rehabil."},{"key":"ref_113","doi-asserted-by":"crossref","unstructured":"Della Villa, F., Di Paolo, S., Santagati, D., Della Croce, E., Lopomo, N.F., Grassi, A., and Zaffagnini, S. (2021). A 2D video-analysis scoring system of 90\u00b0 change of direction technique identifies football players with high knee abduction moment. Knee Surg. Sports Traumatol. Arthrosc., 1\u201310.","DOI":"10.1007\/s00167-021-06571-2"},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1177\/0363546517744313","article-title":"Age Influences Biomechanical Changes After Participation in an Anterior Cruciate Ligament Injury Prevention Program","volume":"46","author":"Gatewood","year":"2018","journal-title":"Am. J. Sports Med."},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1177\/0363546516669326","article-title":"Biomechanical Effects of an Injury Prevention Program in Preadolescent Female Soccer Athletes","volume":"45","author":"Thompson","year":"2017","journal-title":"Am. J. Sports Med."},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.jsams.2006.02.009","article-title":"A new framework for research leading to sports injury prevention","volume":"9","author":"Finch","year":"2006","journal-title":"J. Sci. Med. Sport"},{"key":"ref_117","doi-asserted-by":"crossref","first-page":"5","DOI":"10.4085\/1062-6050-99-16","article-title":"National Athletic Trainers\u2019 Association Position Statement: Prevention of Anterior Cruciate Ligament Injury","volume":"53","author":"Padua","year":"2018","journal-title":"J. Athl. Train."},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1136\/bjsports-2015-095596","article-title":"Critical components of neuromuscular training to reduce ACL injury risk in female athletes: Meta-regression analysis","volume":"50","author":"Sugimoto","year":"2016","journal-title":"Br. J. Sports Med."},{"key":"ref_119","doi-asserted-by":"crossref","first-page":"501","DOI":"10.2165\/00007256-200535060-00004","article-title":"Physiology of Soccer","volume":"35","author":"Chamari","year":"2005","journal-title":"Sports Med."},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s40798-020-00276-5","article-title":"Biomechanical Determinants of Knee Joint Loads Associated with Increased Anterior Cruciate Ligament Loading During Cutting: A Systematic Review and Technical Framework","volume":"6","author":"Donelon","year":"2020","journal-title":"Sports Med. Open"},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1016\/j.jbiomech.2011.04.010","article-title":"The effects of single-leg landing technique on ACL loading","volume":"44","author":"Laughlin","year":"2011","journal-title":"J. Biomech."},{"key":"ref_122","doi-asserted-by":"crossref","unstructured":"Ford, K., DiCesare, C., Myer, G.D., and Hewett, T.E. (2015). Real-Time Biofeedback to Target Risk of Anterior Cruciate Ligament Injury: A Technical Report for Injury Prevention and Rehabilitation. J. Sport Rehabil., 24.","DOI":"10.1123\/jsr.2013-0138"},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"e001091","DOI":"10.1136\/bmjsem-2021-001091","article-title":"Anterior cruciate ligament injury mechanisms through a neurocognition lens: Implications for injury screening","volume":"7","author":"Gokeler","year":"2021","journal-title":"BMJ Open Sport Exerc. Med."},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.ptsp.2014.06.003","article-title":"Novel methods of instruction in ACL injury prevention programs, a systematic review","volume":"16","author":"Benjaminse","year":"2015","journal-title":"Phys. Ther. Sport"},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1007\/s40617-020-00473-4","article-title":"Using Behavioral Skills Training With Video Feedback to Prevent Risk of Injury in Youth Female Soccer Athletes","volume":"13","author":"Harris","year":"2020","journal-title":"Behav. Anal. Pract."},{"key":"ref_126","doi-asserted-by":"crossref","unstructured":"De Sire, A., Marotta, N., Demeco, A., Moggio, L., Paola, P., Marotta, M., Iona, T., Invernizzi, M., Leigheb, M., and Ammendolia, A. (2021). Electromyographic Assessment of Anterior Cruciate Ligament Injury Risk in Male Tennis Players: Which Role for Visual Input? A Proof-of-Concept Study. Diagnostics, 11.","DOI":"10.3390\/diagnostics11060997"},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1136\/jisakos-2020-000475","article-title":"Feedback cues improve the alignment and technique of children performing ACL injury prevention exercises","volume":"6","author":"Boyle","year":"2021","journal-title":"J. ISAKOS Jt. Disord. Orthop. Sports Med."}],"container-title":["International Journal of Environmental Research and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1660-4601\/18\/24\/13351\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T07:51:36Z","timestamp":1760169096000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1660-4601\/18\/24\/13351"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,18]]},"references-count":127,"journal-issue":{"issue":"24","published-online":{"date-parts":[[2021,12]]}},"alternative-id":["ijerph182413351"],"URL":"https:\/\/doi.org\/10.3390\/ijerph182413351","relation":{},"ISSN":["1660-4601"],"issn-type":[{"value":"1660-4601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,18]]}}}