{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T02:17:19Z","timestamp":1762049839217,"version":"build-2065373602"},"reference-count":38,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2022,5,9]],"date-time":"2022-05-09T00:00:00Z","timestamp":1652054400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"European Union\u2019s Horizon 2020 research and innovation program","award":["857159"],"award-info":[{"award-number":["857159"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>An early, extensive, accurate, and cost-effective clinical diagnosis of neurocognitive disorders will have advantages for older people and their families, but also for the health and care systems sustainability and performance. BRAINCODE is a technology that assesses cognitive impairment in older people, differentiating normal from pathologic brain condition, based in an EEG biomarkers evaluation. This paper will address BRAINCODE\u2019s pilot design, which intends to validate its efficacy, to provide guidelines for future studies and to allow its integration on the SHAPES platform. It is expected that BRAINCODE confirms a regular clinical diagnosis and neuropsychologic tests to discriminate \u2018normal\u2019 from pathologic cognitive decline and differentiates mild cognitive impairment from dementia in older adults with\/without subjective cognitive complains.<\/jats:p>","DOI":"10.3390\/ijerph19095768","type":"journal-article","created":{"date-parts":[[2022,5,9]],"date-time":"2022-05-09T21:23:27Z","timestamp":1652131407000},"page":"5768","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["BRAINCODE for Cognitive Impairment Diagnosis in Older Adults: Designing a Case\u2013Control Pilot Study"],"prefix":"10.3390","volume":"19","author":[{"given":"Pedro","family":"Rocha","sequence":"first","affiliation":[{"name":"Departamento de Ci\u00eancias do Comportamento, ICBAS\u2014Instituto de Ci\u00eancias Biom\u00e9dicas Abel Salazar, Universidade do Porto, Rua Jorge de Viterbo Ferreira, 228, 4050-313 Porto, Portugal"},{"name":"CINTESIS\u2014Centro de Investiga\u00e7\u00e3o em Tecnologias e Servi\u00e7os de Sa\u00fade, R. Dr. Pl\u00e1cido da Costa, 4200-450 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8798-0221","authenticated-orcid":false,"given":"Paulina Clara","family":"Dagnino","sequence":"additional","affiliation":[{"name":"Starlab Barcelona SL, Neuroscience Business Unit, Avda. Tibidabo 47 bis, 08035 Barcelona, Spain"}]},{"given":"Ronan","family":"O\u2019Sullivan","sequence":"additional","affiliation":[{"name":"Centre for Gerontology and Rehabilitation, School of Medicine, University College Cork, College Road, T12 K8AF Cork, Ireland"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4704-927X","authenticated-orcid":false,"given":"Aureli","family":"Soria-Frisch","sequence":"additional","affiliation":[{"name":"Starlab Barcelona SL, Neuroscience Business Unit, Avda. Tibidabo 47 bis, 08035 Barcelona, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9214-7805","authenticated-orcid":false,"given":"Constan\u00e7a","family":"Pa\u00fal","sequence":"additional","affiliation":[{"name":"Departamento de Ci\u00eancias do Comportamento, ICBAS\u2014Instituto de Ci\u00eancias Biom\u00e9dicas Abel Salazar, Universidade do Porto, Rua Jorge de Viterbo Ferreira, 228, 4050-313 Porto, Portugal"},{"name":"CINTESIS\u2014Centro de Investiga\u00e7\u00e3o em Tecnologias e Servi\u00e7os de Sa\u00fade, R. Dr. Pl\u00e1cido da Costa, 4200-450 Porto, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2022,5,9]]},"reference":[{"key":"ref_1","unstructured":"(2022, April 11). United Nations Decade of Healthy Ageing (2021\u20132030). Available online: https:\/\/documents-dds-ny.un.org\/doc\/UNDOC\/GEN\/N20\/363\/87\/PDF\/N2036387.pdf?OpenElement."},{"key":"ref_2","unstructured":"World Health Organization (2021). 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