{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T20:35:49Z","timestamp":1777840549784,"version":"3.51.4"},"reference-count":81,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2022,6,4]],"date-time":"2022-06-04T00:00:00Z","timestamp":1654300800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001871","name":"FCT\u2014Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["UIDB\/4255\/2020"],"award-info":[{"award-number":["UIDB\/4255\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Inappropriate prescribing, which encompasses the prescription of potentially inappropriate medications (PIMs) and potential prescribing omissions (PPOs), is a common problem for older people. The STOPP\/START tool enables general practitioners, who are the main prescribers, to identify and reduce the incidence of PIMs and PPOs and appraise an older patient\u2019s prescribed drugs during the diagnosis process to improve the clinical care quality. This study aimed to translate and validate the STOPP\/START screening tool to enable its use by Portuguese physicians. A translation-back translation method including the validation of the obtained Portuguese version was used. Intra- and inter-rater reliability and agreement analyses were used in the validation process. A dataset containing the information of 334 patients was analyzed by one GP twice within a 2-week interval, while a dataset containing the information of 205 patients was independently analyzed by three GPs. Intra-rater reliability assessment led to a Kappa coefficient (\u03ba) of 0.70 (0.65\u20130.74) for the STOPP criteria and 0.60 (0.52\u20130.68) for the START criteria, considered to be substantial and moderate values, respectively. The results of the inter-rater reliability rating were almost perfect for all combinations of raters (\u03ba &gt; 0.93). The version of the STOPP\/START criteria translated into Portuguese represents an improvement in managing the medications prescribed to the elderly. It provides clinicians with a screening tool for detecting potentially inappropriate prescribing in patients older than 65 years old that is reliable and easy to use.<\/jats:p>","DOI":"10.3390\/ijerph19116896","type":"journal-article","created":{"date-parts":[[2022,6,4]],"date-time":"2022-06-04T09:42:32Z","timestamp":1654335752000},"page":"6896","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Inappropriate Prescriptions in Older People\u2014Translation and Adaptation to Portuguese of the STOPP\/START Screening Tool"],"prefix":"10.3390","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0784-5770","authenticated-orcid":false,"given":"Lu\u00eds","family":"Monteiro","sequence":"first","affiliation":[{"name":"CINTESIS\u2014Centre for Health Technology and Services Research, Faculty of Medicine, University of Porto, 4099-002 Porto, Portugal"},{"name":"USF Esgueira +, 3800-322 Aveiro, Portugal"}]},{"given":"Matilde","family":"Monteiro-Soares","sequence":"additional","affiliation":[{"name":"CINTESIS\u2014Centre for Health Technology and Services Research, Faculty of Medicine, University of Porto, 4099-002 Porto, Portugal"},{"name":"MEDCIDS\u2014Department of Community Medicine, Information and Decision in Health, Faculty of Medicine, University of Porto, 4099-002 Porto, Portugal"},{"name":"Escola Superior de Sa\u00fade da Cruz Vermelha Portuguesa, 1300-125 Lisbon, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6279-1421","authenticated-orcid":false,"given":"Cristiano","family":"Matos","sequence":"additional","affiliation":[{"name":"Department of Mathematics, University of Aveiro, 3810-193 Aveiro, Portugal"},{"name":"Escola Superior de Tecnologia da Sa\u00fade de Coimbra, Instituto Polit\u00e9cnico de Coimbra, 3045-093 Coimbra, Portugal"}]},{"given":"In\u00eas","family":"Ribeiro-Vaz","sequence":"additional","affiliation":[{"name":"CINTESIS\u2014Centre for Health Technology and Services Research, Faculty of Medicine, University of Porto, 4099-002 Porto, Portugal"},{"name":"MEDCIDS\u2014Department of Community Medicine, Information and Decision in Health, Faculty of Medicine, University of Porto, 4099-002 Porto, Portugal"},{"name":"Porto Pharmacovigilance Centre, Faculty of Medicine, University of Porto, 4099-002 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1199-2220","authenticated-orcid":false,"given":"Andreia","family":"Teixeira","sequence":"additional","affiliation":[{"name":"CINTESIS\u2014Centre for Health Technology and Services Research, Faculty of Medicine, University of Porto, 4099-002 Porto, Portugal"},{"name":"MEDCIDS\u2014Department of Community Medicine, Information and Decision in Health, Faculty of Medicine, University of Porto, 4099-002 Porto, Portugal"},{"name":"IPVC\u2014Instituto Polit\u00e9cnico de Viana do Castelo, 4900-347 Viana do Castelo, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8561-5167","authenticated-orcid":false,"given":"Carlos","family":"Martins","sequence":"additional","affiliation":[{"name":"CINTESIS\u2014Centre for Health Technology and Services Research, Faculty of Medicine, University of Porto, 4099-002 Porto, Portugal"},{"name":"MEDCIDS\u2014Department of Community Medicine, Information and Decision in Health, Faculty of Medicine, University of Porto, 4099-002 Porto, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2022,6,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1001\/jama.279.15.1200","article-title":"Incidence of adverse drug reactions in hospitalized patients: A meta-analysis of prospective studies","volume":"279","author":"Lazarou","year":"1998","journal-title":"JAMA"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1136\/bmj.329.7456.15","article-title":"Adverse drug reactions as cause of admission to hospital: Prospective analysis of 18,820 patients","volume":"329","author":"Pirmohamed","year":"2004","journal-title":"BMJ"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"331","DOI":"10.2165\/00002018-200629040-00004","article-title":"Influence of pharmacists\u2019 attitudes on adverse drug reaction reporting","volume":"29","author":"Herdeiro","year":"2006","journal-title":"Drug Saf."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1002\/pds.1263","article-title":"Spontaneously reported fatal suspected adverse drug reactions: A 10-year survey from Sweden","volume":"16","author":"Wester","year":"2007","journal-title":"Pharmacoepidemiol. 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