{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T23:46:13Z","timestamp":1772063173807,"version":"3.50.1"},"reference-count":55,"publisher":"MDPI AG","issue":"22","license":[{"start":{"date-parts":[[2022,11,14]],"date-time":"2022-11-14T00:00:00Z","timestamp":1668384000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Resistance training has been shown to acutely increase arterial stiffness (AS), while endurance training appears to decrease AS. However, the findings are from studies in apparently healthy subjects and have limited applicability to patients at low and high cardiovascular risk, for whom combined exercise is recommended. We compared the time course of changes in local and regional indices of AS in response to high-volume combined endurance training (CET) and high-volume combined resistance training (CRT) in patients with coronary artery disease (CAD) and heart failure (HF). We studied 20 men with CAD and HF (10 each) aged 68.3 \u00b1 9.6 years. AS was measured by pulse wave velocity (PWV), and brachial and central blood pressure (BP) were determined after 15 min of rest and 5 and 15 min after the exercise session. All patients completed two sessions on nonconsecutive days. A protocol by time interaction effect was observed for carotid (\u03b72 = 0.21, p = 0.02), aortic (\u03b72 = 0.60, p &lt; 0.001), and femoral (\u03b72 = 0.46, p = 0.01) PWV after CET and CRT, suggesting that PWV decreased after CET and increased after CRT. Decreases in the brachial and central variables of BP across time points were observed in both protocols. CET decreased whereas CRT increased carotid, aortic, and femoral PWV at 15 min after exercise in patients with CAD and HF.<\/jats:p>","DOI":"10.3390\/ijerph192214994","type":"journal-article","created":{"date-parts":[[2022,11,15]],"date-time":"2022-11-15T02:28:04Z","timestamp":1668479284000},"page":"14994","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Arterial Stiffness Response to Acute Combined Training with Different Volumes in Coronary Artery Disease and Heart Failure Patients"],"prefix":"10.3390","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2540-2826","authenticated-orcid":false,"given":"Vanessa","family":"Santos","sequence":"first","affiliation":[{"name":"Exercise and Health Laboratory, CIPER, Faculdade de Motricidade Humana, Universidade de Lisboa, Cruz Quebrada, 1649-004 Lisboa, Portugal"},{"name":"KinesioLab, Research Unit in Human Movement Analysis, Instituto Piaget, 2805-059 Almada, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8786-3498","authenticated-orcid":false,"given":"Lu\u00eds Miguel","family":"Massu\u00e7a","sequence":"additional","affiliation":[{"name":"ICPOL Research Center, Higher Institute of Police Sciences and Internal Security, 1300-352 Lisbon, Portugal"},{"name":"CIDEFES\u2014Research Center in Sport, Physical Education, Exercise and Health, Lus\u00f3fona University, 1749-024 Lisbon, Portugal"}]},{"given":"Vitor","family":"Angarten","sequence":"additional","affiliation":[{"name":"Exercise and Health Laboratory, CIPER, Faculdade de Motricidade Humana, Universidade de Lisboa, Cruz Quebrada, 1649-004 Lisboa, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3934-3986","authenticated-orcid":false,"given":"Xavier","family":"Melo","sequence":"additional","affiliation":[{"name":"Egas Moniz Interdisciplinary Research Center (CiiEM), Egas Moniz School of Health, 2829-511 Almada, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0925-4245","authenticated-orcid":false,"given":"Rita","family":"Pinto","sequence":"additional","affiliation":[{"name":"Structural and Coronary Heart Disease Unit, Centro Cardiovascular da Universidade de Lisboa (CCUL@RISE), Faculty of Medicine, University of Lisbon, 1649-004 Lisboa, Portugal"}]},{"given":"Bo","family":"Fernhall","sequence":"additional","affiliation":[{"name":"College of Nursing and Health Sciences, University of Massachusetts, 100 Morrissey Boulevard, Boston, MA 02125, USA"}]},{"given":"Helena","family":"Santa-Clara","sequence":"additional","affiliation":[{"name":"Exercise and Health Laboratory, CIPER, Faculdade de Motricidade Humana, Universidade de Lisboa, Cruz Quebrada, 1649-004 Lisboa, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2022,11,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.3389\/fimmu.2017.01058","article-title":"Inflammatory Markers for Arterial Stiffness in Cardiovascular Diseases","volume":"8","author":"Mozos","year":"2017","journal-title":"Front. 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