{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T14:56:35Z","timestamp":1773154595950,"version":"3.50.1"},"reference-count":91,"publisher":"MDPI AG","issue":"22","license":[{"start":{"date-parts":[[2022,11,18]],"date-time":"2022-11-18T00:00:00Z","timestamp":1668729600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"European Regional Development Fund (ERDF)","award":["ref. POCI-01-0247-FEDER-069523"],"award-info":[{"award-number":["ref. POCI-01-0247-FEDER-069523"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>This systematic review aims at providing an overview of the state of the art regarding smart wearable systems (SWS) applications to monitor the status of patients suffering from vascular disorders of the lower extremity. Peer-reviewed literature has been analyzed to identify employed data collection methods, system characteristics, and functionalities, and research challenges and limitations to be addressed. The Medline (PubMed) and SCOPUS databases were considered to search for publications describing SWS for remote or continuous monitoring of patients suffering from intermittent claudication, venous ulcers, and diabetic foot ulcers. Publications were first screened based on whether they describe an SWS applicable to the three selected vascular disorders of the lower extremity, including data processing and output to users. Information extracted from publications included targeted disease, clinical parameters to be measured and wearable devices used; system outputs to the user; system characteristics, including capabilities of remote or continuous monitoring or functionalities resulting from advanced data analyses, such as coaching, recommendations, or alerts; challenges and limitations reported; and research outputs. A total of 128 publications were considered in the full-text analysis, and 54 were finally included after eligibility criteria assessment by four independent reviewers. Our results were structured and discussed according to three main topics consisting of data collection, system functionalities, and limitations and challenges.<\/jats:p>","DOI":"10.3390\/ijerph192215231","type":"journal-article","created":{"date-parts":[[2022,11,18]],"date-time":"2022-11-18T03:31:10Z","timestamp":1668742270000},"page":"15231","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Smart Wearable Systems for the Remote Monitoring of Selected Vascular Disorders of the Lower Extremity: A Systematic Review"],"prefix":"10.3390","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8576-1903","authenticated-orcid":false,"given":"Julio","family":"Souza","sequence":"first","affiliation":[{"name":"Department of Community Medicine, Information and Health Decision Sciences (MEDCIDS), Faculty of Medicine of the University of Porto, 4200-450 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4550-0140","authenticated-orcid":false,"given":"Sara","family":"Escadas","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Information and Health Decision Sciences (MEDCIDS), Faculty of Medicine of the University of Porto, 4200-450 Porto, Portugal"}]},{"given":"Isidora","family":"Baxevani","sequence":"additional","affiliation":[{"name":"Department of Materials Science and Technology, University of Crete, 700 13 Iraklio, Greece"}]},{"given":"Daniel","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Information and Health Decision Sciences (MEDCIDS), Faculty of Medicine of the University of Porto, 4200-450 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2113-9653","authenticated-orcid":false,"given":"Alberto","family":"Freitas","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Information and Health Decision Sciences (MEDCIDS), Faculty of Medicine of the University of Porto, 4200-450 Porto, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2022,11,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.artmed.2012.09.003","article-title":"Smart wearable systems: Current status and future challenges","volume":"56","author":"Chan","year":"2012","journal-title":"Artif. Intell. Med."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/s10916-017-0760-1","article-title":"A Systematic Review of Wearable Patient Monitoring Systems\u2014Current Challenges and Opportunities for Clinical Adoption","volume":"41","author":"Baig","year":"2017","journal-title":"J. Med. Syst."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1109\/TSMCC.2009.2032660","article-title":"A Survey on Wearable Sensor-Based Systems for Health Monitoring and Prognosis","volume":"40","author":"Pantelopoulos","year":"2010","journal-title":"IEEE Trans. Syst. Man Cybern. Part C"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/1743-0003-9-21","article-title":"A review of wearable sensors and systems with application in rehabilitation","volume":"9","author":"Patel","year":"2012","journal-title":"J. NeuroEng. Rehabil."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.measurement.2018.06.050","article-title":"A smart wearable system for short-term cardiovascular risk assessment with emotional dynamics","volume":"128","author":"Akan","year":"2018","journal-title":"Measurement"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1109\/EMB.2007.901787","article-title":"Wearable and portable eHealth systems. Technological issues and opportunities for personalized care","volume":"26","author":"Gatzoulis","year":"2007","journal-title":"IEEE Eng. Med. Biol. Mag."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.1016\/j.jvs.2017.05.111","article-title":"Exercise training for intermittent claudication","volume":"66","author":"McDermott","year":"2017","journal-title":"J. Vasc. Surg."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.jvn.2015.01.003","article-title":"Chronic venous disease, and venous leg ulcers: An evidence-based update","volume":"33","author":"Kelechi","year":"2015","journal-title":"J. Vasc. Nurs."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1053\/j.semvascsurg.2019.02.001","article-title":"The diabetic foot: Pathophysiology, evaluation, and treatment","volume":"31","author":"Bandyk","year":"2018","journal-title":"Semin. Vasc. Surg."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1177\/193229681100500636","article-title":"Diabetic foot ulcers and vascular insufficiency: Our population has changed, but our methods have not","volume":"5","author":"Armstrong","year":"2011","journal-title":"J. Diabetes Sci. Technol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"e308","DOI":"10.1016\/S2589-7500(19)30128-1","article-title":"Innovative intelligent insole system reduces diabetic foot ulcer recurrence at plantar sites: A prospective, randomised, proof-of-concept study","volume":"1","author":"Abbott","year":"2019","journal-title":"Lancet Digit. Health"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1016\/S0140-6736(05)67699-4","article-title":"Treatment for diabetic foot ulcers","volume":"366","author":"Cavanagh","year":"2005","journal-title":"Lancet"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"2367","DOI":"10.1056\/NEJMra1615439","article-title":"Diabetic foot ulcers and their recurrence","volume":"376","author":"Armstrong","year":"2017","journal-title":"N. Engl. J. Med."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1002\/dmrr.2702","article-title":"Footwear and offloading in-terventions to prevent and heal foot ulcers and reduce plantar pressure in patients with diabetes: A systematic review","volume":"32","author":"Bus","year":"2016","journal-title":"Diabetes Metab. Res. Rev."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"22","DOI":"10.4236\/jst.2011.12004","article-title":"Using wearable sensors for remote healthcare monitoring system","volume":"01","author":"Abidoye","year":"2011","journal-title":"J. Sens. Technol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/2049-3258-72-28","article-title":"Smart wearable body sensors for patient self-assessment and monitoring","volume":"72","author":"Appelboom","year":"2014","journal-title":"Arch. Public Health"},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Hegarty, M., Grant, E., Reid, L., and Henderson, T. (2008, January 20\u201322). A dynamic compression system for improving ulcer healing: Design of a sensing garment. Proceedings of the 2008 IEEE International Conference on Multisensor Fusion and Integration for Intelligent Systems, Seoul, Republic of Korea.","DOI":"10.1109\/MFI.2008.4648053"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"S5","DOI":"10.1016\/j.jvs.2006.12.037","article-title":"Inter-society consensus for the management of peripheral arterial disease (TASC II)","volume":"45","author":"Norgren","year":"2007","journal-title":"J. Vasc. Surg."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1161\/CIRCRESAHA.114.303517","article-title":"Lower extremity manifestations of peripheral artery disease: The pathophysiologic and functional implications of leg ischemia","volume":"116","author":"McDermott","year":"2015","journal-title":"Circ. Res."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.ejvs.2018.03.004","article-title":"The 2017 ESC guidelines on the diagnosis and treatment of peripheral arterial diseases, in collaboration with the European society for vascular surgery (ESVS)","volume":"55","author":"Halliday","year":"2018","journal-title":"Eur. J. Vasc. Endovasc. Surg."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.ejvs.2012.09.009","article-title":"Availability of supervised exercise programs and the role of structured home-based exercise in peripheral arterial disease","volume":"44","author":"Makris","year":"2012","journal-title":"Eur. J. Vasc. Endovasc. Surg."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1833","DOI":"10.1016\/j.jvs.2021.03.008","article-title":"Wearable activity monitors in home-based exercise therapy for patients with intermittent claudication: A systematic review","volume":"73","author":"Chan","year":"2021","journal-title":"J. Vasc. Surg."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.ejvs.2013.03.030","article-title":"Do behaviour-change techniques contribute to the effectiveness of exercise therapy in patients with intermittent claudication? A systematic review","volume":"46","author":"Galea","year":"2013","journal-title":"Eur. J. Vasc. Endovasc. Surg."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.math.2013.02.007","article-title":"Effect of plantar intrinsic muscle training on medial longitudinal arch morphology and dynamic function","volume":"18","author":"Mulligan","year":"2013","journal-title":"Man. Ther."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Sartor, C.D., Hasue, R.H., Cacciari, L.P., Butugan, M.K., Watari, R., P\u00e1ssaro, A.C., Giacomozzi, C., and Sacco, I.C. (2014). Effects of strengthening, stretching and functional training on foot function in patients with diabetic neuropathy: Results of a randomized controlled trial. BMC Musculoskelet. Disord., 15.","DOI":"10.1186\/1471-2474-15-137"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1980","DOI":"10.2337\/diacare.27.8.1980","article-title":"Variability in activity may precede diabetic foot ulceration","volume":"27","author":"Armstrong","year":"2004","journal-title":"Diabetes Care"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1038\/s41746-018-0073-x","article-title":"Clinical validation of smartphone-based activity tracking in peripheral artery disease patients","volume":"1","author":"Ata","year":"2018","journal-title":"NPJ Digit. Med."},{"key":"ref_28","first-page":"44","article-title":"Use of a remote temperature monitoring mat for the early identification of foot ulcers","volume":"32","author":"Banks","year":"2020","journal-title":"Wounds"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/1757-1146-5-32","article-title":"A novel approach to mapping load transfer from the plantar surface of the foot to the walls of the total contact cast: A proof of concept study","volume":"5","author":"Begg","year":"2012","journal-title":"J. Foot Ankle Res."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"2075","DOI":"10.1016\/j.apmr.2012.06.019","article-title":"New monitoring technology to objectively assess adherence to prescribed footwear and assistive devices during ambulatory activity","volume":"93","author":"Bus","year":"2012","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1177\/1534734618784080","article-title":"A Foreign Body Through the Shoe of a Person with Diabetic Peripheral Neuropathy Alters Contralateral Biomechanics: Captured Through Innovative Plantar Pressure Technology","volume":"17","author":"Chatwin","year":"2018","journal-title":"Int. J. Low Extrem. Wounds"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1111\/sms.13511","article-title":"Using wearable monitors to assess daily walking limitations induced by ischemic pain in peripheral artery disease","volume":"29","author":"Chaudru","year":"2019","journal-title":"Scand. J. Med. Sci. Sports"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.3389\/fphys.2018.01061","article-title":"Full Band Spectra Analysis of Gait Acceleration Signals for Peripheral Arterial Disease Patients","volume":"9","author":"Chidean","year":"2018","journal-title":"Front. Physiol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.ejvs.2012.11.027","article-title":"Free-living physical activity as a novel outcome measure in patients with intermittent claudication","volume":"45","author":"Clarke","year":"2013","journal-title":"Eur. J. Vasc. Endovasc. Surg."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"e18739","DOI":"10.2196\/18739","article-title":"Satisfaction and Acceptability of Telemonitored Home-Based Exercise in Patients with Intermittent Claudication: Pragmatic Observational Pilot Study","volume":"8","author":"Cornelis","year":"2021","journal-title":"JMIR Rehabil. Assist. Technol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/j.clinbiomech.2012.03.001","article-title":"Impact of strut height on offloading capacity of removable cast walkers","volume":"27","author":"Crews","year":"2012","journal-title":"Clin. Biomech."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1002\/dmrr.2366","article-title":"Biofeedback can reduce foot pressure to a safe level and without causing new at-risk zones in patients with diabetes and peripheral neuropathy","volume":"29","author":"Allet","year":"2013","journal-title":"Diabetes Metab. Res. Rev."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1159\/000513729","article-title":"The Feasibility and Effectiveness of Wearable Sensor Technology in the Management of Elderly Diabetics with Foot Ulcer Remission: A Proof-Of-Concept Pilot Study with Six Cases","volume":"67","author":"Du","year":"2021","journal-title":"Gerontology"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1016\/j.amjcard.2018.05.018","article-title":"Effects of a 12-Week mHealth Program on Functional Capacity and Physical Activity in Patients with Peripheral Artery Disease","volume":"122","author":"Duscha","year":"2018","journal-title":"Am. J. Cardiol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.ejvs.2014.04.003","article-title":"Physical activity monitoring in patients with peripheral arterial disease: Validation of an activity monitor","volume":"48","author":"Fokkenrood","year":"2014","journal-title":"Eur. J. Vasc. Endovasc. Surg."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"973","DOI":"10.2337\/dc16-2294","article-title":"Feasibility and Efficacy of a Smart Mat Technology to Predict Devel-opment of Diabetic Plantar Ulcers","volume":"40","author":"Frykberg","year":"2017","journal-title":"Diabetes Care"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1177\/1358863X09106836","article-title":"The effect of claudication pain on temporal and spatial gait measures during self-paced ambulation","volume":"15","author":"Gardner","year":"2010","journal-title":"Vasc. Med."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1016\/j.jvs.2007.07.038","article-title":"Patterns of ambulatory activity in subjects with and without intermittent claudication","volume":"46","author":"Gardner","year":"2007","journal-title":"J. Vasc. Surg."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1016\/j.jvs.2008.06.062","article-title":"Association between daily ambulatory activity patterns and exercise performance in patients with intermittent claudication","volume":"48","author":"Gardner","year":"2008","journal-title":"J. Vasc. Surg."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1016\/j.jvs.2021.12.071","article-title":"Light and moderate intensity physical activity are associated with better ambulation, quality of life, and vascular measurements in patients with claudication","volume":"75","author":"Gardner","year":"2022","journal-title":"J. Vasc. Surg."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"e001107","DOI":"10.1161\/JAHA.114.001107","article-title":"Step-monitored home exercise improves ambulation, vascular function, and inflammation in symptomatic patients with peripheral artery disease: A randomized controlled trial","volume":"3","author":"Gardner","year":"2014","journal-title":"J. Am. Heart Assoc."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1161\/CIRCULATIONAHA.110.963066","article-title":"Efficacy of quantified home-based exercise and supervised exercise in patients with intermittent claudication: A randomized controlled trial","volume":"123","author":"Gardner","year":"2011","journal-title":"Circulation"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1016\/j.jvs.2014.04.053","article-title":"Applicability of global positioning system for the assessment of walking ability in patients with arterial claudication","volume":"60","author":"Gernigon","year":"2014","journal-title":"J. Vasc. Surg."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"108074","DOI":"10.1016\/j.diabres.2020.108074","article-title":"Accuracy of a foot temperature monitoring mat for predicting diabetic foot ulcers in patients with recent wounds or partial foot amputation","volume":"161","author":"Gordon","year":"2020","journal-title":"Diabetes Res. Clin. Pract."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1111\/srt.13042","article-title":"Moisture sensor for exudative wounds\u2014A pilot study","volume":"27","author":"Henricson","year":"2021","journal-title":"Skin Res. Technol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"112974","DOI":"10.1016\/j.bios.2021.112974","article-title":"Bioimpedance method for monitoring venous ulcers: Clinical proof-of-concept study","volume":"178","author":"Kekonen","year":"2021","journal-title":"Biosens. Bioelectron."},{"key":"ref_52","doi-asserted-by":"crossref","unstructured":"Kekonen, A., Bergelin, M., Eriksson, J.E., Vesa, M., Johansson, M., and Viik, J. (2018, January 8\u201310). Long-term monitoring of acute wound healing from beneath the primary wound dressings. Proceedings of the Biennial Baltic Electronics Conference\u2014BEC, Tallinn, Estonia.","DOI":"10.1109\/BEC.2018.8600956"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1097\/WON.0000000000000631","article-title":"FOOTFIT physical activity mHealth intervention for minimally ambulatory individuals with venous leg ulcers: A randomized controlled trial: A randomized controlled trial","volume":"47","author":"Kelechi","year":"2020","journal-title":"J Wound Ostomy Cont. Nurs."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"e15015","DOI":"10.2196\/15015","article-title":"A Lower Leg Physical Activity Intervention for Individuals With Chronic Venous Leg Ulcers: Randomized Controlled Trial","volume":"8","author":"Kelechi","year":"2020","journal-title":"JMIR mHealth uHealth"},{"key":"ref_55","first-page":"E44","article-title":"Remote Temperature Monitoring in Diabetic Foot Ulcer Detection","volume":"30","author":"Killeen","year":"2018","journal-title":"Wounds"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/j.ejvs.2014.03.001","article-title":"Physical activity monitoring in patients with intermittent claudication","volume":"47","author":"Lauret","year":"2014","journal-title":"Eur. J. Vasc. Endovasc. Surg."},{"key":"ref_57","first-page":"1","article-title":"Using wireless near-infrared spectroscopy to predict wound prognosis in diabetic foot ulcers","volume":"33","author":"Lin","year":"2020","journal-title":"Adv. Skin Wound Care"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1093\/ptj\/85.6.579","article-title":"Relationship between changes in activity and plantar ulcer recurrence in a patient with diabetes mellitus","volume":"85","author":"Lott","year":"2005","journal-title":"Phys. Ther."},{"key":"ref_59","doi-asserted-by":"crossref","unstructured":"Madavi, M.V., and Giripunje, S.D. (2015, January 18\u201322). Design and Implementation of Wearable Device for Neuropathic Diabetic Foot Patients. Proceedings of the International Conference on Emerging Trends in Engineering and Technology\u2014ICETET, Kobe, Japan.","DOI":"10.1109\/ICETET.2015.14"},{"key":"ref_60","doi-asserted-by":"crossref","unstructured":"Mancilla, R.B., Daul, C., Martinez, J.G., Salas, L.L., Wolf, D., and Hernandez, A.V. (2021, January 15\u201320). A Quantitative Method for the Detection of Temperature Differences on the Sole of the Foot in Diabetic Patients. Proceedings of the Pan American Health Care Exchanges\u2014PAHCE, Sevilla, Spain.","DOI":"10.1109\/GMEPE\/PAHCE50215.2021.9434852"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"766","DOI":"10.20965\/jrm.2012.p0766","article-title":"Insole-type simultaneous measurement system of plantar pressure and shear force during gait for diabetic patients","volume":"24","author":"Mori","year":"2012","journal-title":"J. Robot. Mechatron."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"104343","DOI":"10.1016\/j.ijmedinf.2020.104343","article-title":"A smart wearable device for monitoring and self-management of diabetic foot: A proof of concept study","volume":"146","author":"Moulaei","year":"2021","journal-title":"Int. J. Med. Inform."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1016\/0003-9993(94)90004-3","article-title":"Hip and ankle walking strategies: Effect on peak plantar pressures and implications for neuropathic ulceration","volume":"75","author":"Mueller","year":"1994","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1053\/ejvs.2001.1581","article-title":"The role of pedometers in the assessment of intermittent claudication","volume":"23","author":"Nasr","year":"2002","journal-title":"Eur. J. Vasc. Endovasc. Surg."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/j.jvsv.2020.11.007","article-title":"Interface pressure changes under compression bandages during period of wearing","volume":"9","author":"Ning","year":"2021","journal-title":"J. Vasc. Surg. Venous Lymphat. Disord."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1111\/j.1464-5491.2009.02835.x","article-title":"Plantar pressures in diabetic patients with foot ulcers which have remained healed","volume":"26","author":"Owings","year":"2009","journal-title":"Diabet. Med."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"e12460","DOI":"10.2196\/12460","article-title":"Continuous Temperature-Monitoring Socks for Home Use in Patients with Diabetes: Observational Study","volume":"20","author":"Reyzelman","year":"2018","journal-title":"J. Med. Internet Res."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"e31870","DOI":"10.2196\/31870","article-title":"An Evaluation of Real-world Smart Sock-Based Temperature Monitoring Data as a Physiological Indicator of Early Diabetic Foot Injury: Case-Control Study","volume":"6","author":"Reyzelman","year":"2022","journal-title":"JMIR Form. Res."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.2337\/diacare.17.9.1002","article-title":"In-shoe foot pressure measurements in diabetic patients with at-risk feet and in healthy subjects","volume":"17","author":"Sarnow","year":"1994","journal-title":"Diabetes Care"},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1177\/1932296818822538","article-title":"Feasibility of a Low-Intensity, Technology-Based Intervention for In-creasing Physical Activity in Adults at Risk for a Diabetic Foot Ulcer: A Mixed-Methods Study","volume":"13","author":"Schneider","year":"2019","journal-title":"J. Diabetes Sci. Technol."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"e32934","DOI":"10.2196\/32934","article-title":"Utilization of a Smart Sock for the Remote Monitoring of Patients with Peripheral Neuropathy: Cross-sectional Study of a Real-world Registry","volume":"6","author":"Scholten","year":"2022","journal-title":"JMIR Form. Res."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1097\/00008483-199701000-00006","article-title":"Physical activity monitoring in patients with peripheral arterial occlusive disease","volume":"17","author":"Sieminski","year":"1997","journal-title":"J. Cardiopulm. Rehabil."},{"key":"ref_73","doi-asserted-by":"crossref","unstructured":"Torreblanca Gonz\u00e1lez, J., G\u00f3mez-Mart\u00edn, B., Hern\u00e1ndez Encinas, A., Mart\u00edn-Vaquero, J., Queiruga-Dios, A., and Mart\u00ednez-Nova, A. (2021). The Use of Infrared Thermography to Develop and Assess a Wearable Sock and Monitor Foot Temperature in Diabetic Subjects. Sensors, 21.","DOI":"10.3390\/s21051821"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1109\/TBCAS.2020.3043538","article-title":"A Novel Low-Cost Wireless Footwear System for Monitoring Diabetic Foot Patients","volume":"15","author":"Wang","year":"2021","journal-title":"IEEE Trans. Biomed. Circuits Syst."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"5350616","DOI":"10.1155\/2017\/5350616","article-title":"Development of a Plantar Load Estimation Algorithm for Evaluation of Forefoot Load of Diabetic Patients during Daily Walks Using a Foot Motion Sensor","volume":"2017","author":"Watanabe","year":"2017","journal-title":"J. Diabetes Res."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1177\/1932296814546528","article-title":"A novel shear reduction insole effect on the thermal response to walking stress, balance, and gait","volume":"8","author":"Wrobel","year":"2014","journal-title":"J. Diabetes Sci. Technol."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1053\/j.jfas.2019.05.009","article-title":"Temperature- and Pressure-Regulating Insoles for Prevention of Diabetic Foot Ulcers","volume":"59","author":"Yavuz","year":"2020","journal-title":"J. Foot Ankle Surg."},{"key":"ref_78","doi-asserted-by":"crossref","unstructured":"Zaffar, M., Tariq, M.T., Arsalan, M.A., Qureshi, N.K., and Cheema, H.M. (2016, January 24\u201327). A low-cost, non-invasive sensory device for early diagnosis of diabetic peripheral neuropathy. Proceedings of the 3rd IEEE EMBS International Conference on Biomedical and Health Informatics\u2014BHI, Las Vegas, NV, USA.","DOI":"10.1109\/BHI.2016.7455868"},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1016\/0003-9993(93)90094-Q","article-title":"Sensate and insensate in-shoe plantar pressures","volume":"74","author":"Zhu","year":"1993","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijmedinf.2008.09.002","article-title":"STARE-HI\u2014Statement on reporting of evaluation studies in Health Informatics","volume":"78","author":"Talmon","year":"2009","journal-title":"Int. J. Med. Inform."},{"key":"ref_81","doi-asserted-by":"crossref","unstructured":"Chowdhury, M.E., Khandakar, A., Qiblawey, Y., Reaz, M.B.I., Islam, M.T., and Touati, F. (2020). Machine learning in wearable biomedical systems. Sports Science and Human Health\u2014Different Approaches, IntechOpen.","DOI":"10.5772\/intechopen.93228"},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"102111","DOI":"10.1016\/j.artmed.2021.102111","article-title":"A review of AI and Data Science support for cancer management","volume":"117","author":"Parimbelli","year":"2021","journal-title":"Artif. Intell. Med."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"e14017","DOI":"10.2196\/14017","article-title":"Literature on wearable technology for connected health: Scoping review of research trends, advances, and barriers","volume":"21","author":"Zdravevski","year":"2019","journal-title":"J. Med. Internet Res."},{"key":"ref_84","doi-asserted-by":"crossref","unstructured":"Khan, S., and Alam, M. (2021). Wearable internet of things for personalized healthcare: Study of trends and latent research. Health Informatics: A Computational Perspective in Healthcare, Springer.","DOI":"10.1007\/978-981-15-9735-0_3"},{"key":"ref_85","doi-asserted-by":"crossref","unstructured":"Macdonald, E.M., Perrin, B.M., Cleeland, L., and Kingsley, M.I.C. (2021). Podiatrist-delivered health coaching to facilitate the use of a smart insole to support foot health monitoring in people with diabetes-related peripheral neuropathy. Sensors, 21.","DOI":"10.3390\/s21123984"},{"key":"ref_86","unstructured":"Mahn, T.G. (2013). Wireless Medical Technologies: Navigating Government Regulation in New Medical Age, Fish & Richardson. A Report on Medical Device Regulation."},{"key":"ref_87","unstructured":"Directive 2007\/47\/EC (2022, September 20). Approximation of the Laws of the Member States Relating to Active Implantable Medical Devices, Council Directive 93\/42\/EEC Concerning Medical Devices and Directive 98\/8\/EC Concerning the Placing of Biocidal Products on the Market. European Parliament and Council. Available online: https:\/\/eur-lex.europa.eu\/LexUriServ\/LexUriServ.do?uri=OJ:L:2007:247:0021:0055:en:PDF."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1109\/RBME.2015.2427254","article-title":"Body sensor networks: In the era of big data and beyond","volume":"8","author":"Poon","year":"2015","journal-title":"IEEE Rev. Biomed. Eng."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1109\/TBCAS.2011.2176726","article-title":"An ultralow energy biomedical signal processing system operating at near-threshold","volume":"5","author":"Hulzink","year":"2011","journal-title":"IEEE Trans. Biomed. Circuits Syst."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/1756-0381-7-22","article-title":"Applications of the MapReduce programming framework to clinical big data analysis: Current landscape and future trends","volume":"7","author":"Mohammed","year":"2014","journal-title":"BioData Min."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1109\/MVT.2018.2810317","article-title":"Wearable Communications in 5G: Challenges and Enabling Technologies","volume":"13","author":"Sun","year":"2018","journal-title":"IEEE Veh. Technol. Mag."}],"container-title":["International Journal of Environmental Research and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1660-4601\/19\/22\/15231\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:20:54Z","timestamp":1760145654000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1660-4601\/19\/22\/15231"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,18]]},"references-count":91,"journal-issue":{"issue":"22","published-online":{"date-parts":[[2022,11]]}},"alternative-id":["ijerph192215231"],"URL":"https:\/\/doi.org\/10.3390\/ijerph192215231","relation":{},"ISSN":["1660-4601"],"issn-type":[{"value":"1660-4601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,18]]}}}