{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T14:02:27Z","timestamp":1768312947281,"version":"3.49.0"},"reference-count":54,"publisher":"MDPI AG","issue":"24","license":[{"start":{"date-parts":[[2022,12,7]],"date-time":"2022-12-07T00:00:00Z","timestamp":1670371200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"S\u00e3o Paulo Research Foundation (FAPESP)","award":["#2016\/02258-3- scholarship"],"award-info":[{"award-number":["#2016\/02258-3- scholarship"]}]},{"name":"S\u00e3o Paulo Research Foundation (FAPESP)","award":["001- scholarship"],"award-info":[{"award-number":["001- scholarship"]}]},{"name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior (Capes)","award":["#2016\/02258-3- scholarship"],"award-info":[{"award-number":["#2016\/02258-3- scholarship"]}]},{"name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior (Capes)","award":["001- scholarship"],"award-info":[{"award-number":["001- scholarship"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Extended periods of time on screen devices and sitting are the main activities that characterize sedentary behavior (SB), which negatively impacts the quality of life. This negative influence was demonstrated mainly by cross-sectional studies performed in high-income countries in which the effects of screen time on health-related quality of life (HRQoL) is not considered. Thus, we analyzed the association between the different domains of SB (i.e., subdomains of screen time\u2014television, computer, cellphone) and the HRQoL in adults that live in Brazil during two years of follow-up. The sample included 331 adults. Subdomains of screen time (i.e., watching television, using computers, and cellphones) and of HRQoL (i.e., physical functioning, role-physical, bodily pain, general health, vitality, social functioning, role-emotional, mental health, and current health perception) were assessed by a structured questionnaire and SF-36, respectively. Our results indicate a significant increase in screen time during the two years of follow-up. Linear regression models indicated that although domains of SB were differently associated with HRQoL, in general, screen time was negatively associated with social functioning and positively associated with physical functioning during locomotion and activities of daily living (ADL), role-physical (i.e., physical issues during work and ADLs), and role-emotional (i.e., emotional issues during work and ADLs) after the two-year follow-up. In conclusion, screen time may positively or negatively influence some domains of HRQoL in adults.<\/jats:p>","DOI":"10.3390\/ijerph192416389","type":"journal-article","created":{"date-parts":[[2022,12,7]],"date-time":"2022-12-07T03:27:57Z","timestamp":1670383677000},"page":"16389","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Association between Different Domains of Sedentary Behavior and Health-Related Quality of Life in Adults: A Longitudinal Study"],"prefix":"10.3390","volume":"19","author":[{"given":"Catarina Covolo","family":"Scarabottolo","sequence":"first","affiliation":[{"name":"Graduate Program in Movement Sciences, Physical Education Department, School of Technology and Sciences, S\u00e3o Paulo State University (Unesp), Presidente Prudente 19060-900, Brazil"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6192-4667","authenticated-orcid":false,"given":"William Rodrigues","family":"Tebar","sequence":"additional","affiliation":[{"name":"Center of Clinical and Epidemiological Research, University Hospital, University of Sao Paulo, S\u00e3o Paulo 05403-000, Brazil"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4239-0716","authenticated-orcid":false,"given":"Paulo Henrique","family":"Ara\u00fajo Guerra","sequence":"additional","affiliation":[{"name":"Department of Medicine, Federal University of Fronteira Sul, Chapec\u00f3 89802-112, Brazil"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4947-9329","authenticated-orcid":false,"given":"Clarice Maria de Lucena","family":"Martins","sequence":"additional","affiliation":[{"name":"Department of Physical Education, Federal University of Paraiba, Jo\u00e3o Pessoa 58051-900, Brazil"}]},{"given":"Gerson","family":"Ferrari","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, Universidad Aut\u00f3noma de Chile, Providencia 7500912, Chile"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4640-7733","authenticated-orcid":false,"given":"Victor Spiandor","family":"Beretta","sequence":"additional","affiliation":[{"name":"Graduate Program in Movement Sciences, Physical Education Department, School of Technology and Sciences, S\u00e3o Paulo State University (Unesp), Presidente Prudente 19060-900, Brazil"}]},{"given":"Diego Giulliano Destro","family":"Christofaro","sequence":"additional","affiliation":[{"name":"Graduate Program in Movement Sciences, Physical Education Department, School of Technology and Sciences, S\u00e3o Paulo State University (Unesp), Presidente Prudente 19060-900, Brazil"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1186\/s12966-017-0525-8","article-title":"Sedentary Behavior Research Network (SBRN)\u2014Terminology Consensus Project Process and Outcome","volume":"14","author":"Tremblay","year":"2017","journal-title":"Int. J. Behav. Nutr. Phys. Act."},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Bauman, A.E., Petersen, C.B., Blond, K., Rangul, V., and Hardy, L.L. (2018). The Descriptive Epidemiology of Sedentary Behaviour, Springer.","DOI":"10.1007\/978-3-319-61552-3_4"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1007\/s13679-017-0256-9","article-title":"Screen Time, Other Sedentary Behaviours, and Obesity Risk in Adults: A Review of Reviews","volume":"6","author":"Biddle","year":"2017","journal-title":"Curr. Obes. Rep."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"964132","DOI":"10.3389\/fendo.2022.964132","article-title":"Physical Activity, Sedentary Behavior, and the Risk of Type 2 Diabetes: A Two-Sample Mendelian Randomization Analysis in the European Population","volume":"13","author":"Deng","year":"2022","journal-title":"Front. Endocrinol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1018460","DOI":"10.3389\/fpubh.2022.1018460","article-title":"Association between Sedentary Behavior, Physical Activity, and Cardiovascular Disease-Related Outcomes in Adults\u2014A Meta-Analysis and Systematic Review","volume":"10","author":"Liang","year":"2022","journal-title":"Front. Public Health"},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Chau, J.Y., Grunseit, A.C., Chey, T., Stamatakis, E., Brown, W.J., Matthews, C.E., Bauman, A.E., and van der Ploeg, H.P. (2013). Daily Sitting Time and All-Cause Mortality: A Meta-Analysis. PLoS ONE, 8.","DOI":"10.1371\/journal.pone.0080000"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.jped.2018.04.011","article-title":"Prevalence of Excessive Screen Time and TV Viewing among Brazilian Adolescents: A Systematic Review and Meta-Analysis","volume":"95","author":"Schaan","year":"2019","journal-title":"J. Pediatr."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"2143","DOI":"10.1590\/1413-81232022276.11842021","article-title":"Sedentary Behavior and Health-Related Quality of Life in Adolescents","volume":"27","author":"Loch","year":"2022","journal-title":"Cien. Saude Colet."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"101452","DOI":"10.1016\/j.eclinm.2022.101452","article-title":"Changes and Correlates of Screen Time in Adults and Children during the COVID-19 Pandemic: A Systematic Review and Meta-Analysis","volume":"48","author":"Trott","year":"2022","journal-title":"eClinicalMedicine"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"9791281","DOI":"10.1155\/2019\/9791281","article-title":"Physical Activity, Sedentary Behavior, and Quality of Life among University Students","volume":"2019","author":"Nowak","year":"2019","journal-title":"Biomed Res. Int."},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Sohn, S.Y., Rees, P., Wildridge, B., Kalk, N.J., and Carter, B. (2019). Prevalence of Problematic Smartphone Usage and Associated Mental Health Outcomes amongst Children and Young People: A Systematic Review, Meta-Analysis and GRADE of the Evidence. BMC Psychiatry, 19.","DOI":"10.1186\/s12888-019-2350-x"},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Meyer, J., McDowell, C., Lansing, J., Brower, C., Smith, L., Tully, M., and Herring, M. (2020). Changes in Physical Activity and Sedentary Behavior in Response to COVID-19 and Their Associations with Mental Health in 3052 US Adults. Int. J. Environ. Res. Public Health, 17.","DOI":"10.3390\/ijerph17186469"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"630586","DOI":"10.3389\/fnut.2021.630586","article-title":"Increased Screen Time Is Associated with Alcohol Desire and Sweetened Foods Consumption During the COVID-19 Pandemic","volume":"8","author":"Tebar","year":"2021","journal-title":"Front. Nutr."},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"(1995). Whoqol Group the World Health Organization Quality of Life Assessment (WHOQOL): Position Paper from the World Health Organization. Soc. Sci. Med., 41, 1403\u20131409.","DOI":"10.1016\/0277-9536(95)00112-K"},{"key":"ref_15","unstructured":"Mayo, N. (2015). Dictionary of Quality of Life and Health Outcomes Measurement, International Society for Quality of Life Research. [1st ed.]."},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Wu, X.Y., Han, L.H., Zhang, J.H., Luo, S., Hu, J.W., and Sun, K. (2017). The Influence of Physical Activity, Sedentary Behavior on Health-Related Quality of Life among the General Population of Children and Adolescents: A Systematic Review. PLoS ONE, 12.","DOI":"10.1371\/journal.pone.0187668"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/j.jpeds.2015.04.079","article-title":"Trajectories and Predictors of Health-Related Quality of Life during Childhood","volume":"167","author":"Vella","year":"2015","journal-title":"J. Pediatr."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1352\/1944-7558-121.1.1","article-title":"Moving Us toward a Theory of Individual Quality of Life","volume":"121","author":"Schalock","year":"2016","journal-title":"Am. J. Intellect. Dev. Disabil."},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"de Rezende, L.F.M., Rodrigues Lopes, M., Rey-L\u00f3pez, J.P., Matsudo, V.K.R., and Luiz, O.D.C. (2014). Sedentary Behavior and Health Outcomes: An Overview of Systematic Reviews. PLoS ONE, 9.","DOI":"10.1371\/journal.pone.0105620"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1111\/obr.12302","article-title":"Is the Relationship between Sedentary Behaviour and Cardiometabolic Health in Adolescents Independent of Dietary Intake? A Systematic Review","volume":"16","author":"Fletcher","year":"2015","journal-title":"Obes. Rev. Off. J. Int. Assoc. Study Obes."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"100337","DOI":"10.1016\/j.ijchp.2022.100337","article-title":"Associations between Sedentary Behavior and Negative Emotions in Adolescents during Home Confinement: Mediating Role of Social Support and Sleep Quality","volume":"23","author":"Zou","year":"2023","journal-title":"Int. J. Clin. Health Psychol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1080\/17437199.2017.1396191","article-title":"Sedentary Behaviours and Health-Related Quality of Life. A Systematic Review and Meta-Analysis","volume":"12","author":"Boberska","year":"2018","journal-title":"Health Psychol. Rev."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1097\/GME.0000000000001837","article-title":"Physical Activity Domains Are Differently Related with Quality of Life in Breast Cancer Survivors: A Cross-Sectional Study","volume":"28","author":"Ribeiro","year":"2021","journal-title":"Menopause"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1186\/s12966-020-01042-2","article-title":"Advancing the Global Physical Activity Agenda: Recommendations for Future Research by the 2020 WHO Physical Activity and Sedentary Behavior Guidelines Development Group","volume":"17","author":"DiPietro","year":"2020","journal-title":"Int. J. Behav. Nutr. Phys. Act."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1136\/bjsports-2020-102955","article-title":"World Health Organization 2020 Guidelines on Physical Activity and Sedentary Behaviour","volume":"54","author":"Bull","year":"2020","journal-title":"Br. J. Sports Med."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1016\/S0140-6736(16)30370-1","article-title":"Does Physical Activity Attenuate, or Even Eliminate, the Detrimental Association of Sitting Time with Mortality? A Harmonised Meta-Analysis of Data from More than 1 Million Men and Women","volume":"388","author":"Ekelund","year":"2016","journal-title":"Lancet"},{"key":"ref_27","unstructured":"(2022, August 27). IBGE\u2014Instituto Brasileiro de Geografia e Estat\u00edstica Pir\u00e2mide Et\u00e1ria\u2014Presidente Prudente (SP), Available online: https:\/\/censo2010.ibge.gov.br\/sinopse\/webservice\/frm_piramide.php?codigo=354140."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1097\/MBP.0000000000000446","article-title":"Physical Activity Is More Related to Adiposity in Hypertensive than Nonhypertensive Middle-Aged and Older Adults","volume":"25","author":"Tebar","year":"2020","journal-title":"Blood. Press. Monit."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1605139","DOI":"10.3389\/ijph.2022.1605139","article-title":"Association of High Blood Pressure With Physical Activity, Screen-Based Sedentary Time, and Sedentary Breaks in a 2-Year Cohort of Community Dwelling Adults","volume":"67","author":"Tebar","year":"2022","journal-title":"Int. J. Public. Health"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1186\/s12955-022-01981-3","article-title":"Analysis of Different Domains of Physical Activity with Health-Related Quality of Life in Adults: 2-Year Cohort","volume":"20","author":"Scarabottolo","year":"2022","journal-title":"Health Qual. Life Outcomes"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1590\/S1415-790X2013000400009","article-title":"Brazilian Normative Data for the Short Form 36 Questionnaire, Version 2","volume":"16","author":"Laguardia","year":"2013","journal-title":"Rev. Bras. Epidemiol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1097\/00005650-199206000-00002","article-title":"The MOS 36-Item Short-Form Health Survey (SF-36). I. Conceptual Framework and ItemSelection","volume":"30","author":"Ware","year":"1992","journal-title":"Med. Care"},{"key":"ref_33","unstructured":"Associa\u00e7\u00e3o Brasileira de Empresas de Pesquisa\u2014ABEP (2021). Crit\u00e9rio de Classifica\u00e7\u00e3o Econ\u00f4mica Brasil, ABEP."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1093\/ajcn\/36.5.936","article-title":"A Short Questionnaire for the Measurement of Habitual Physical Activity in Epidemiological Studies","volume":"36","author":"Baecke","year":"1982","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Tebar, W.R., Ritti-Dias, R.M., Fernandes, R.A., Damato, T.M.M., de Barros, M.V.G., Mota, J., Andersen, L.B., and Christofaro, D.G.D. (2022). Validity and Reliability of the Baecke Questionnaire against Accelerometer-Measured Physical Activity in Community Dwelling Adults According to Educational Level. PLoS ONE, 17.","DOI":"10.1371\/journal.pone.0270265"},{"key":"ref_36","unstructured":"George, D., and Mallery, M. (2010). SPSS for Windows Step by Step: A Simple Guide and Reference, 17.0 Update, Pearson. [10th ed.]."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"2705","DOI":"10.1016\/j.numecd.2022.08.024","article-title":"Sedentary Behavior and the Risk of Stroke: A Systematic Review and Dose-Response Meta-Analysis","volume":"32","author":"Wang","year":"2022","journal-title":"Nutr. Metab. Cardiovasc. Dis."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"327","DOI":"10.2337\/dc09-0493","article-title":"Deleterious Associations of Sitting Time and Television Viewing Time with Cardiometabolic Risk Biomarkers: Australian Diabetes, Obesity and Lifestyle (AusDiab) Study 2004\u20132005","volume":"33","author":"Thorp","year":"2010","journal-title":"Diabetes Care"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1136\/bjsports-2011-085662","article-title":"Television Viewing Time and Reduced Life Expectancy: A Life Table Analysis","volume":"46","author":"Veerman","year":"2012","journal-title":"Br. J. Sports Med."},{"key":"ref_40","doi-asserted-by":"crossref","unstructured":"Wang, X., Li, Y., and Fan, H. (2019). The Associations between Screen Time-Based Sedentary Behavior and Depression: A Systematic Review and Meta-Analysis. BMC Public Health, 19.","DOI":"10.1186\/s12889-019-7904-9"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.ypmed.2014.09.007","article-title":"Associations of Television Viewing Time with Adults\u2019 Well-Being and Vitality","volume":"69","author":"Dempsey","year":"2014","journal-title":"Prev. Med."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1186\/1477-7525-9-47","article-title":"Longitudinal Association of Physical Activity and Sedentary Behavior during Leisure Time with Health-Related Quality of Life in Community-Dwelling Older Adults","volume":"9","author":"Graciani","year":"2011","journal-title":"Health Qual. Life Outcomes"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1037\/0003-066X.53.9.1017","article-title":"Internet Paradox. A Social Technology that Reduces Social Involvement and Psychological Well-Being?","volume":"53","author":"Kraut","year":"1998","journal-title":"Am. Psychol."},{"key":"ref_44","first-page":"V","article-title":"Health Risks Associated with Mobile Phones Use","volume":"8","author":"Naeem","year":"2014","journal-title":"Int. J. Health Sci."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1186\/1479-5868-8-98","article-title":"Systematic Review of Sedentary Behaviour and Health Indicators in School-Aged Children and Youth","volume":"8","author":"Tremblay","year":"2011","journal-title":"Int. J. Behav. Nutr. Phys. Act."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1038\/oby.2005.65","article-title":"Sedentary Behavior, Physical Activity, and the Metabolic Syndrome among U.S. Adults","volume":"13","author":"Ford","year":"2005","journal-title":"Obes. Res."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"669042","DOI":"10.3389\/fpsyt.2021.669042","article-title":"Excessive Smartphone Use Is Associated with Health Problems in Adolescents and Young Adults","volume":"12","author":"Wacks","year":"2021","journal-title":"Front. Psychiatry"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1007\/s11469-016-9684-0","article-title":"Mental Health Concerns in the Digital Age","volume":"15","author":"Scott","year":"2017","journal-title":"Int. J. Ment. Health Addict."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1142\/S1013702518300010","article-title":"Musculoskeletal Disorder and Pain Associated with Smartphone Use: A Systematic Review of Biomechanical Evidence. Hong Kong Physiother","volume":"38","author":"Eitivipart","year":"2018","journal-title":"J. Off. Publ. Hong Kong Physiother. Assoc. Ltd. Wu Li Chih Liao"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.chb.2018.03.026","article-title":"Distress Tolerance and Mindfulness Mediate Relations between Depression and Anxiety Sensitivity with Problematic Smartphone Use","volume":"84","author":"Elhai","year":"2018","journal-title":"Comput. Human Behav."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1556\/2006.4.2015.010","article-title":"Relationship of Smartphone Use Severity with Sleep Quality, Depression, and Anxiety in University Students","volume":"4","author":"Demirci","year":"2015","journal-title":"J. Behav. Addict."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1186\/1479-5868-10-79","article-title":"The Relationship between Cell Phone Use, Physical and Sedentary Activity, and Cardiorespiratory Fitness in a Sample of U.S. College Students","volume":"10","author":"Lepp","year":"2013","journal-title":"Int. J. Behav. Nutr. Phys. Act."},{"key":"ref_53","doi-asserted-by":"crossref","unstructured":"Thom\u00e9e, S. (2018). Mobile Phone Use and Mental Health. A Review of the Research That Takes a Psychological Perspective on Exposure. Int. J. Environ. Res. Public Health, 15.","DOI":"10.3390\/ijerph15122692"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"2080","DOI":"10.1038\/s41366-020-00650-z","article-title":"Ultra-processed food and the risk of overweight and obesity: A systematic review and meta-analysis of observational studies","volume":"44","author":"Askari","year":"2020","journal-title":"Int. J. Obes."}],"container-title":["International Journal of Environmental Research and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1660-4601\/19\/24\/16389\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:35:30Z","timestamp":1760146530000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1660-4601\/19\/24\/16389"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,7]]},"references-count":54,"journal-issue":{"issue":"24","published-online":{"date-parts":[[2022,12]]}},"alternative-id":["ijerph192416389"],"URL":"https:\/\/doi.org\/10.3390\/ijerph192416389","relation":{},"ISSN":["1660-4601"],"issn-type":[{"value":"1660-4601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,7]]}}}