{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T04:26:17Z","timestamp":1768537577679,"version":"3.49.0"},"reference-count":234,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2023,2,19]],"date-time":"2023-02-19T00:00:00Z","timestamp":1676764800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia (FCT)","doi-asserted-by":"publisher","award":["LA\/P\/0069\/2020"],"award-info":[{"award-number":["LA\/P\/0069\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia (FCT)","doi-asserted-by":"publisher","award":["UIDB\/04292\/2020"],"award-info":[{"award-number":["UIDB\/04292\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia (FCT)","doi-asserted-by":"publisher","award":["UIDP\/50017\/2020+UIDB\/50017\/2020"],"award-info":[{"award-number":["UIDP\/50017\/2020+UIDB\/50017\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia (FCT)","doi-asserted-by":"publisher","award":["SFRH\/BD\/139831\/2018"],"award-info":[{"award-number":["SFRH\/BD\/139831\/2018"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia (FCT)","doi-asserted-by":"publisher","award":["IT057-18-7253"],"award-info":[{"award-number":["IT057-18-7253"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Marine and Environmental Sciences Centre (MARE)","doi-asserted-by":"publisher","award":["LA\/P\/0069\/2020"],"award-info":[{"award-number":["LA\/P\/0069\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Marine and Environmental Sciences Centre (MARE)","doi-asserted-by":"publisher","award":["UIDB\/04292\/2020"],"award-info":[{"award-number":["UIDB\/04292\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Marine and Environmental Sciences Centre (MARE)","doi-asserted-by":"publisher","award":["UIDP\/50017\/2020+UIDB\/50017\/2020"],"award-info":[{"award-number":["UIDP\/50017\/2020+UIDB\/50017\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Marine and Environmental Sciences Centre (MARE)","doi-asserted-by":"publisher","award":["SFRH\/BD\/139831\/2018"],"award-info":[{"award-number":["SFRH\/BD\/139831\/2018"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Marine and Environmental Sciences Centre (MARE)","doi-asserted-by":"publisher","award":["IT057-18-7253"],"award-info":[{"award-number":["IT057-18-7253"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Centre for Environmental and Marine Studies (CESAM)","doi-asserted-by":"publisher","award":["LA\/P\/0069\/2020"],"award-info":[{"award-number":["LA\/P\/0069\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Centre for Environmental and Marine Studies (CESAM)","doi-asserted-by":"publisher","award":["UIDB\/04292\/2020"],"award-info":[{"award-number":["UIDB\/04292\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Centre for Environmental and Marine Studies (CESAM)","doi-asserted-by":"publisher","award":["UIDP\/50017\/2020+UIDB\/50017\/2020"],"award-info":[{"award-number":["UIDP\/50017\/2020+UIDB\/50017\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Centre for Environmental and Marine Studies (CESAM)","doi-asserted-by":"publisher","award":["SFRH\/BD\/139831\/2018"],"award-info":[{"award-number":["SFRH\/BD\/139831\/2018"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Centre for Environmental and Marine Studies (CESAM)","doi-asserted-by":"publisher","award":["IT057-18-7253"],"award-info":[{"award-number":["IT057-18-7253"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Human Potential Operational Programme (National Strategic Reference Framework 2007\u20132013)","doi-asserted-by":"publisher","award":["LA\/P\/0069\/2020"],"award-info":[{"award-number":["LA\/P\/0069\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Human Potential Operational Programme (National Strategic Reference Framework 2007\u20132013)","doi-asserted-by":"publisher","award":["UIDB\/04292\/2020"],"award-info":[{"award-number":["UIDB\/04292\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Human Potential Operational Programme (National Strategic Reference Framework 2007\u20132013)","doi-asserted-by":"publisher","award":["UIDP\/50017\/2020+UIDB\/50017\/2020"],"award-info":[{"award-number":["UIDP\/50017\/2020+UIDB\/50017\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Human Potential Operational Programme (National Strategic Reference Framework 2007\u20132013)","doi-asserted-by":"publisher","award":["SFRH\/BD\/139831\/2018"],"award-info":[{"award-number":["SFRH\/BD\/139831\/2018"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Human Potential Operational Programme (National Strategic Reference Framework 2007\u20132013)","doi-asserted-by":"publisher","award":["IT057-18-7253"],"award-info":[{"award-number":["IT057-18-7253"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005727","name":"University of Coimbra","doi-asserted-by":"publisher","award":["LA\/P\/0069\/2020"],"award-info":[{"award-number":["LA\/P\/0069\/2020"]}],"id":[{"id":"10.13039\/501100005727","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005727","name":"University of Coimbra","doi-asserted-by":"publisher","award":["UIDB\/04292\/2020"],"award-info":[{"award-number":["UIDB\/04292\/2020"]}],"id":[{"id":"10.13039\/501100005727","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005727","name":"University of Coimbra","doi-asserted-by":"publisher","award":["UIDP\/50017\/2020+UIDB\/50017\/2020"],"award-info":[{"award-number":["UIDP\/50017\/2020+UIDB\/50017\/2020"]}],"id":[{"id":"10.13039\/501100005727","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005727","name":"University of Coimbra","doi-asserted-by":"publisher","award":["SFRH\/BD\/139831\/2018"],"award-info":[{"award-number":["SFRH\/BD\/139831\/2018"]}],"id":[{"id":"10.13039\/501100005727","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005727","name":"University of Coimbra","doi-asserted-by":"publisher","award":["IT057-18-7253"],"award-info":[{"award-number":["IT057-18-7253"]}],"id":[{"id":"10.13039\/501100005727","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>In recent decades, pollution levels have increased, mainly as a result of the intensive anthropogenic activities such industrial development, intensive agricultural practices, among others. The impact of metals and organic contaminants is, nowadays, a great concern to the scientific and political communities. Copper compounds are the main sold pesticides in Europe, as well as herbicides, including glyphosate. Diphenyl ethers are the second ones most sold. Glyphosate and copper compounds are intensively studied, but the opposite is seen in the case of diphenyl ethers, including fluorinated pesticides (e.g., oxyfluorfen). Some research has been performed to increase the knowledge about these contaminants, daily inputted on the aquatic systems and with dangerous effects at physical and biochemical levels on the organisms. A wide range of biomarkers (e.g., growth, survival, reproductive success, enzymatic activity, lipid metabolism) has been applied to determine the potential effects in many species. This review intends to: (a) perform a compilation of the knowledge in previous research about the action mode of organic (fluorinated-based herbicide) and inorganic (copper-based pesticides) contaminants; (b) carry out an information survey about the lethal and sub-lethal effects of the fluorinated-based pesticides, namely the oxyfluorfen and the copper-based pesticides, on aquatic species from different trophic levels, according to in vitro and in vivo studies; (c) understand the impact of oxyfluorfen and copper-based pesticides, considering their effects reported in in vitro studies and, simultaneously, the authorized concentrations by legal organizations and the effective concentrations of each pollutant found in the environment. The literature analyzed revealed noxious effects of Cu and oxyfluorfen to aquatic organisms, including freshwater and marine species, even when exposed to the reference as well as to environmental concentrations, thus highlighting the importance of more monitoring and ecotoxicological studies, to chemical pollutants and different species from different ecological niches, to sustain and improve the legislation.<\/jats:p>","DOI":"10.3390\/ijerph20043706","type":"journal-article","created":{"date-parts":[[2023,2,20]],"date-time":"2023-02-20T03:29:06Z","timestamp":1676863746000},"page":"3706","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["The Lethal and Sub-Lethal Effects of Fluorinated and Copper-Based Pesticides\u2014A Review"],"prefix":"10.3390","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9601-943X","authenticated-orcid":false,"given":"Andreia F.","family":"Mesquita","sequence":"first","affiliation":[{"name":"Department of Biology and CESAM, University of Aveiro, 3810-193 Aveiro, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9326-187X","authenticated-orcid":false,"given":"Fernando J. M.","family":"Gon\u00e7alves","sequence":"additional","affiliation":[{"name":"Department of Biology and CESAM, University of Aveiro, 3810-193 Aveiro, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8611-7183","authenticated-orcid":false,"given":"Ana M. M.","family":"Gon\u00e7alves","sequence":"additional","affiliation":[{"name":"Department of Biology and CESAM, University of Aveiro, 3810-193 Aveiro, Portugal"},{"name":"University of Coimbra, MARE-Marine and Environmental Sciences Centre\/ARNET\u2014Aquatic Research Network, Department of Life Sciences, 3000-456 Coimbra, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2023,2,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.jfluchem.2014.06.014","article-title":"Successful fluorine-containing herbicide agrochemicals","volume":"167","author":"Fujiwara","year":"2014","journal-title":"J. Fluor. Chem."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/j.scitotenv.2013.12.065","article-title":"A review on the occurrence of micropollutants in the aquatic environment and their fate and removal during wastewater treatment","volume":"473\u2013474","author":"Luo","year":"2014","journal-title":"Sci. Total Environ."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1146\/annurev-environ-100809-125342","article-title":"Global Water Pollution and Human Health","volume":"35","author":"Schwarzenbach","year":"2010","journal-title":"Annu. Rev. Environ. Resour."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"4115","DOI":"10.1016\/j.watres.2010.05.032","article-title":"Pan-European survey on the occurrence of selected polar organic persistent pollutants in ground water","volume":"44","author":"Loos","year":"2010","journal-title":"Water Res."},{"key":"ref_5","unstructured":"FAO (2020). Pesticides Use, FAO."},{"key":"ref_6","unstructured":"Eurostat (2022, March 11). Agri-Environmental Indicator\u2014Consumption of Pesticides\u2014Statistics Explained. Available online: https:\/\/ec.europa.eu\/eurostat\/statistics-explained\/index.php?title=Agri-environmental_indicator_-_consumption_of_pesticides."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1002\/ps.4368","article-title":"Forward selection for multiple resistance across the non-selective glyphosate, glufosinate and oxyfluorfen herbicides in Lolium weed species","volume":"73","author":"Osuna","year":"2017","journal-title":"Pest Manag. Sci."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1002\/ps.1219","article-title":"Detection of resistance to acetolactate synthase inhibitors in weeds with emphasis on DNA-based techniques: A review","volume":"62","author":"Corbett","year":"2006","journal-title":"Pest Manag. Sci."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"935","DOI":"10.2307\/3870048","article-title":"Biosynthesis of Branched Chain Amino Acids: From Test Tube to Field","volume":"7","author":"Singh","year":"1995","journal-title":"Plant Cell"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1289\/ehp.9087263","article-title":"Overview of herbicide mechanisms of action","volume":"87","author":"Duke","year":"1990","journal-title":"Environ. Health Perspect."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1007\/s00253-011-3796-z","article-title":"Structure, function and selective inhibition of bacterial acetyl-coa carboxylase","volume":"93","author":"Polyak","year":"2012","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"961","DOI":"10.2533\/chimia.2011.961","article-title":"Protoporphyrinogen Oxidase Inhibitor: An Ideal Target for Herbicide Discovery","volume":"65","author":"Hao","year":"2011","journal-title":"Chim. Int. J. Chem."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.pestbp.2018.08.010","article-title":"Biochemical and physiological mode of action of tiafenacil, a new protoporphyrinogen IX oxidase-inhibiting herbicide","volume":"152","author":"Park","year":"2018","journal-title":"Pestic. Biochem. Physiol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"9388","DOI":"10.1002\/anie.201302365","article-title":"4-Hydroxyphenylpyruvate Dioxygenase Inhibitors in Combination with Safeners: Solutions for Modern and Sustainable Agriculture","volume":"52","author":"Ahrens","year":"2013","journal-title":"Angew. Chem. Int. Ed."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1002\/ps.560","article-title":"Target sites for herbicides: Entering the 21st century","volume":"58","author":"Wakabayashi","year":"2002","journal-title":"Pest Manag. Sci."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1016\/S0045-6535(02)00017-6","article-title":"Effect of concentration, moisture and soil type on the dissipation of flufenacet from soil","volume":"47","author":"Gupta","year":"2002","journal-title":"Chemosphere"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1002\/ps.714","article-title":"Flufenacet herbicide treatment phenocopies the fiddlehead mutant in Arabidopsis thaliana","volume":"59","author":"Meissner","year":"2003","journal-title":"Pest Manag. Sci."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Mesquita, A., Gon\u00e7alves, F., Rocha, C., Marques, J., and Gon\u00e7alves, A. (2021). Biochemical Effects of Two Pesticides in Three Different Temperature Scenarios on the Diatom Thalassiosira weissflogii. Processes, 9.","DOI":"10.3390\/pr9071247"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1016\/j.ecoenv.2011.07.006","article-title":"Differential physiological and biochemical responses of two cyanobacteria Nostoc muscorum and Phormidium foveolarum against oxyfluorfen and UV-B radiation","volume":"74","author":"Sheeba","year":"2011","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/S0048-3575(02)00009-3","article-title":"Effect of oxyfluorfen and diuron alone and in mixture on antioxidative enzymes of Scenedesmus obliquus","volume":"72","author":"Geoffroy","year":"2002","journal-title":"Pestic. Biochem. Physiol."},{"key":"ref_21","first-page":"521","article-title":"toxicological effects of the herbicide oxyfluorfen on acetylcholinesterase in two fish species: Oreochromis niloticus and Gambusia affinis","volume":"37","author":"Hassanein","year":"2002","journal-title":"J. Environ. Sci. Health Part A Toxic\/Hazard. Subst. Environ. Eng."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.pestbp.2005.10.007","article-title":"Toxicological effects of oxyfluorfen on oxidative stress enzymes in tilapia Oreochromis niloticus","volume":"85","author":"Peixoto","year":"2006","journal-title":"Pestic. Biochem. Physiol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1007\/s002449900492","article-title":"Induction of Hsp70 by the Herbicide Oxyfluorfen (Goal) in the Egyptian Nile Fish, Oreochromis niloticus","volume":"37","author":"Hassanein","year":"1999","journal-title":"Arch. Environ. Contam. Toxicol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.envpol.2007.12.010","article-title":"Chronic copper exposure and fatty acid composition of the amphipod Dikerogammarus villosus: Results from a field study","volume":"156","author":"Maazouzi","year":"2008","journal-title":"Environ. Pollut."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Ritter, A., Dittami, S.M., Goulitquer, S., Correa, J.A., Boyen, C., Potin, P., and Tonon, T. (2014). Transcriptomic and metabolomic analysis of copper stress acclimation in Ectocarpus siliculosus highlights signaling and tolerance mechanisms in brown algae. BMC Plant Biol., 14.","DOI":"10.1186\/1471-2229-14-116"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1111\/j.1469-8137.2008.02626.x","article-title":"Copper stress induces biosynthesis of octadecanoid and eicosanoid oxygenated derivatives in the brown algal kelp Laminaria digitata","volume":"180","author":"Ritter","year":"2008","journal-title":"New Phytol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.aquatox.2016.05.008","article-title":"Biochemical and toxicological effects of organic (herbicide Primextra\u00ae Gold TZ) and inorganic (copper) compounds on zooplankton and phytoplankton species","volume":"177","author":"Filimonova","year":"2016","journal-title":"Aquat. Toxicol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"22180","DOI":"10.1007\/s11356-018-2302-x","article-title":"Ecotoxicological and biochemical mixture effects of an herbicide and a metal at the marine primary producer diatom Thalassiosira weissflogii and the primary consumer copepod Acartia tonsa","volume":"25","author":"Filimonova","year":"2018","journal-title":"Environ. Sci. Pollut. Res."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.ecolind.2017.10.007","article-title":"Fatty acids profiles modifications in the bivalves Cerastoderma edule and Scrobicularia plana in response to copper sulphate","volume":"85","author":"Mesquita","year":"2018","journal-title":"Ecol. Indic."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"209","DOI":"10.3844\/ojbsci.2014.209.217","article-title":"Copper stress on cellular contents and fatty acid profiles in chlorella species","volume":"14","author":"Sibi","year":"2014","journal-title":"Online J. Biol. Sci."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00425-021-03573-9","article-title":"Regression models to stratify the copper toxicity responses and tolerance mechanisms of Glycine max (L.) Merr. plants","volume":"253","author":"Gomes","year":"2021","journal-title":"Planta"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1016\/j.ecolind.2017.10.065","article-title":"Assessment of metal exposure (uranium and copper) by the response of a set of integrated biomarkers in a stream shredder","volume":"95","author":"Tagliaferro","year":"2018","journal-title":"Ecol. Indic."},{"key":"ref_33","unstructured":"EEA (2012). EEA Water 2012 Report: European Waters\u2014Assessment of Status and Pressures, EEA."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.envpol.2007.08.016","article-title":"Application of biochemical fingerprinting and fatty acid methyl ester profiling to assess the effect of the pesticide Atradex on aquatic microbial communities","volume":"153","author":"Brooks","year":"2008","journal-title":"Environ. Pollut."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1590\/S0102-695X2011005000060","article-title":"Effects of heavy metals and light levels on the biosynthesis of carotenoids and fatty acids in the macroalgae Gracilaria tenuistipitata (var. liui Zhang & Xia)","volume":"21","author":"Pinto","year":"2011","journal-title":"Rev. Bras. Farm."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/s12011-013-9727-3","article-title":"Changes of Blue Mussels Mytilus edulis L. Lipid Composition Under Cadmium and Copper Toxic Effect","volume":"154","author":"Fokina","year":"2013","journal-title":"Biol. Trace Element Res."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0742-8413(91)90065-2","article-title":"Alterations of microsomal lipid synthesis in gill cells of bivalve mollusc Mizuhopecten yessoensis in response to cadmium accumulation","volume":"99","author":"Chelomin","year":"1991","journal-title":"Comp. Biochem. Physiol. Part C Comp. Pharmacol."},{"key":"ref_38","first-page":"498","article-title":"Toxicity effects of copper on the marine diatom, Chaetoceros calcitrans","volume":"8","author":"Anu","year":"2016","journal-title":"Reg. Stud. Mar. Sci."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1186\/2193-1801-2-498","article-title":"Effect of copper sulfate on the survival and growth performance of Caspian Sea kutum, Rutilus frisii kutum","volume":"2","author":"Gharedaashi","year":"2013","journal-title":"Springerplus"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.aquatox.2007.07.003","article-title":"The effects of copper on the morphological and functional development of zebrafish embryos","volume":"84","author":"Johnson","year":"2007","journal-title":"Aquat. Toxicol."},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Mayor, D.J., Gray, N.B., Elver-Evans, J., Midwood, A.J., and Thornton, B. (2013). Metal-Macrofauna Interactions Determine Microbial Community Structure and Function in Copper Contaminated Sediments. PLoS ONE, 8.","DOI":"10.1371\/journal.pone.0064940"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-019-52925-9","article-title":"Copper sulphate impact on the antioxidant defence system of the marine bivalves Cerastoderma edule and Scrobicularia plana","volume":"9","author":"Mesquita","year":"2019","journal-title":"Sci. Rep."},{"key":"ref_43","first-page":"333","article-title":"Determination of LC 50 of Copper Sulfate and Lead (II) Nitrate and Behavioral Responses of Grass Carp (Ctenopharyngodon idella)","volume":"9","author":"Nekoubin","year":"2012","journal-title":"Walailak J. Sci. Technol. WJST"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"106245","DOI":"10.1016\/j.aquatox.2022.106245","article-title":"Effects of wildfire ash on the growth and biochemical profiles of the aquatic macrophyte Lemna minor","volume":"250","author":"Mesquita","year":"2022","journal-title":"Aquat. Toxicol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.resmic.2011.11.003","article-title":"Adaptation of Rhodococcus erythropolis cells for growth and bioremediation under extreme conditions","volume":"163","year":"2012","journal-title":"Res. Microbiol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.ecoenv.2019.02.034","article-title":"Impacts of S-metolachlor and terbuthylazine in fatty acid and carbohydrate composition of the benthic clam Scrobicularia plana","volume":"173","author":"Mesquita","year":"2019","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.heares.2005.10.015","article-title":"Sub-lethal concentrations of waterborne copper are toxic to lateral line neuromasts in zebrafish (Danio rerio)","volume":"213","author":"Moreno","year":"2006","journal-title":"Hear. Res."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.ecoenv.2014.03.021","article-title":"ROI-scavenging enzyme activities as toxicity biomarkers in three species of marine microalgae exposed to model contaminants (copper, Irgarol and atrazine)","volume":"104","author":"Lozano","year":"2014","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s002440010234","article-title":"Effects of Copper and Cadmium Exposure on Functional Responses of Hemocytes in the Clam, Tapes philippinarum","volume":"41","author":"Matozzo","year":"2001","journal-title":"Arch. Environ. Contam. Toxicol."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1080\/08927014.2017.1384468","article-title":"Effect of copper on multiple successional stages of a marine fouling assemblage","volume":"33","author":"McElroy","year":"2017","journal-title":"Biofouling"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1163\/156854011X587496","article-title":"Antioxidant Responses and Lipid Peroxidation of Penaeus Indicus Postlarvae Subjected to Sublethal Copper Exposure","volume":"84","author":"Paila","year":"2011","journal-title":"Crustaceana"},{"key":"ref_52","first-page":"39","article-title":"Study of carbohydrate metabolism in selected tissues of freshwater mussel, Lamellidens marginalis under copper sulphate toxicity","volume":"27","author":"Satyaparameshwar","year":"2006","journal-title":"J. Environ. Biol."},{"key":"ref_53","doi-asserted-by":"crossref","unstructured":"Jesus, F., Mesquita, F., Aldama, E.V., Marques, A., Gon\u00e7alves, A.M.M., Magalh\u00e3es, L., Nogueira, A.J.A., R\u00e9, A., Campos, I., and Pereira, J.L. (2023). Do Freshwater and Marine Bivalves Differ in Their Response to Wildfire Ash? Effects on the Antioxidant Defense System and Metal Body Burden. Int. J. Environ. Res. Public Health, 20.","DOI":"10.3390\/ijerph20021326"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.1016\/j.ecoenv.2011.07.012","article-title":"A multiple biomarker approach to investigate the effects of copper on the marine bivalve mollusc, Mytilus edulis","volume":"74","author":"Moody","year":"2011","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/S0025-326X(01)00060-1","article-title":"Contaminant-stimulated Reactive Oxygen Species Production and Oxidative Damage in Aquatic Organisms","volume":"42","author":"Livingstone","year":"2001","journal-title":"Mar. Pollut. Bull."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S1382-6689(02)00126-6","article-title":"Fish bioaccumulation and biomarkers in environmental risk assessment: A review","volume":"13","author":"Beyer","year":"2003","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"215S","DOI":"10.1093\/ajcn\/81.1.215S","article-title":"Polyphenols: Antioxidants and beyond","volume":"81","author":"Scalbert","year":"2005","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_58","unstructured":"Sies, H. (1985). Oxidative Stress, Academic Press."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/j.aquaculture.2006.04.031","article-title":"Pharmacological and immunocytochemical investigation of the role of catecholamines on larval metamorphosis by \u03b2-adrenergic-like receptor in the bivalve Meretrix meretrix","volume":"258","author":"Wang","year":"2006","journal-title":"Aquaculture"},{"key":"ref_60","unstructured":"Amiard, J., and Amiard-Triquet, C. (2008). Les Biomarqueurs Dans L\u2019\u00e9valuation de L\u2019\u00e9tat \u00c9cologique Des Milieux Aquatiques, Lavoisier. Editions Technique & Doc."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"1977","DOI":"10.1016\/j.chemosphere.2007.12.014","article-title":"Modulation of antioxidant defences in digestive gland of Perna viridis (L.), on mercury exposures","volume":"71","author":"Verlecar","year":"2008","journal-title":"Chemosphere"},{"key":"ref_62","doi-asserted-by":"crossref","unstructured":"Amiard, J.-C., Caquet, T., and Lagadic, L. (2021). Use of Biomarkers for Environmental Quality Assessment, CRC Press.","DOI":"10.1201\/9781003211020"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1006\/eesa.1999.1804","article-title":"Metabolic Enzyme Activities in Fish Gills as Biomarkers of Exposure to Petroleum Hydrocarbons","volume":"44","author":"Gagnon","year":"1999","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/S0045-6535(01)00029-7","article-title":"Lactate dehydrogenase activity as an effect criterion in toxicity tests with Daphnia magna straus","volume":"45","author":"Diamantino","year":"2001","journal-title":"Chemosphere"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1006\/pest.2000.2534","article-title":"Changes in Fatty Acid Composition of Neutral Lipid in Mung Bean Cotyledons by Oxyfluorfen-Induced Peroxidation","volume":"69","author":"Watanabe","year":"2001","journal-title":"Pestic. Biochem. Physiol."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/BF02789456","article-title":"Cadmium-induced excretion of urinary lipid metabolites, DNA damage, glutathione depletion, and hepatic lipid peroxidation in sprague-dawley rats","volume":"52","author":"Bagchi","year":"1996","journal-title":"Biol. Trace Element Res."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1007\/s11802-015-2464-9","article-title":"Effects of waterborne Cu and Cd on anti-oxidative response, lipid peroxidation and heavy metals accumulation in abalone Haliotis discus hannai ino","volume":"14","author":"Lei","year":"2015","journal-title":"J. Ocean Univ. China"},{"key":"ref_68","first-page":"294","article-title":"Aquafeed imprint on bogue (Boops boops) populations and the value of fatty acids as indicators of aquaculture-ecosystem interaction: Are we using them properly?","volume":"414\u2013415","author":"Montero","year":"2013","journal-title":"Aquaculture"},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"2308","DOI":"10.3168\/jds.S0022-0302(01)74678-4","article-title":"Copper Status, Serum Cholesterol, and Milk Fatty Acid Profile in Holstein Cows Fed Varying Concentrations of Copper","volume":"84","author":"Engle","year":"2001","journal-title":"J. Dairy Sci."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.ecolind.2015.01.031","article-title":"Biochemical and populational responses of an aquatic bioindicator species, Daphnia longispina, to a commercial formulation of a herbicide (Primextra\u00ae Gold TZ) and its active ingredient (S-metolachlor)","volume":"53","author":"Neves","year":"2015","journal-title":"Ecol. Indic."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"53","DOI":"10.3354\/meps09920","article-title":"Bioconversion of fatty acids at the basis of marine food webs: Insights from a compound-specific stable isotope analysis","volume":"465","author":"Boeckx","year":"2012","journal-title":"Mar. Ecol. Prog. Ser."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.ecolind.2015.12.006","article-title":"Fatty acids\u2019 profiles as indicators of stress induced by of a common herbicide on two marine bivalves species: Cerastoderma edule (Linnaeus, 1758) and Scrobicularia plana (da Costa, 1778)","volume":"63","author":"Mesquita","year":"2016","journal-title":"Ecol. Indic."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3354\/meps09559","article-title":"Fatty acids as dietary tracers in benthic food webs","volume":"446","author":"Kelly","year":"2012","journal-title":"Mar. Ecol. Prog. Ser."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"275","DOI":"10.3354\/meps265275","article-title":"Fatty acid composition of the adipose tissue of polar bears and of their prey: Ringed seals, bearded seals and harp seals","volume":"265","author":"Andersen","year":"2003","journal-title":"Mar. Ecol. Prog. Ser."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1890\/02-4105","article-title":"Quantitative fatty acid signature analysis: A new method of estimating predator diets","volume":"74","author":"Iverson","year":"2004","journal-title":"Ecol. Monogr."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1111\/j.1748-7692.2006.00079.x","article-title":"Studying trophic ecology in marine ecosystems using fatty acids: A primer on analysis and interpretation","volume":"22","author":"Budge","year":"2006","journal-title":"Mar. Mammal Sci."},{"key":"ref_77","first-page":"20437","article-title":"Studies on Sub Lethal Effect of Cypermethrin and Oxyfluorfen on Biochemical Parameters of Earthworm Species, Eisenia Foetida Savigny, 1826","volume":"6","author":"Begul","year":"2017","journal-title":"Int. J. Innov. Res. Sci."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1007\/s10646-021-02410-9","article-title":"Toxicity of copper on marine diatoms, Chaetoceros calcitrans and Nitzchia closterium from Cochin estuary, India","volume":"30","author":"Neethu","year":"2021","journal-title":"Ecotoxicology"},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"30188","DOI":"10.1007\/s11356-019-06170-2","article-title":"Excess copper effects on growth, uptake of water and nutrients, carbohydrates, and PSII photochemistry revealed by OJIP transients in Citrus seedlings","volume":"26","author":"Li","year":"2019","journal-title":"Environ. Sci. Pollut. Res."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1034\/j.1600-0706.2000.880110.x","article-title":"Trade-offs in evolutionary immunology: Just what is the cost of immunity?","volume":"88","author":"Lochmiller","year":"2000","journal-title":"Oikos"},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.algal.2017.01.010","article-title":"Effects of chrysolaminarin synthase knockdown in the diatom Thalassiosira pseudonana: Implications of reduced carbohydrate storage relative to green algae","volume":"23","author":"Hildebrand","year":"2017","journal-title":"Algal Res."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1128\/MMBR.64.4.847-867.2000","article-title":"Microbial Biofilms: From Ecology to Molecular Genetics","volume":"64","author":"Davey","year":"2000","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.carbpol.2005.04.008","article-title":"Isolation and characterization of extracellular polysaccharides produced by Pseudomonas fluorescens Biovar II","volume":"61","author":"Hung","year":"2005","journal-title":"Carbohydr. Polym."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/S0958-6946(01)00112-1","article-title":"Microbial Polysaccharides from Gram-Negative Bacteria","volume":"11","author":"Sutherland","year":"2001","journal-title":"Int. Dairy J."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1023\/A:1016354713289","article-title":"Extracellular Polysaccharides of Copper-Sensitive and Copper-Resintant Pseudomonas Aeruginosa Strain: Synthesis, Chemical Nature and Copper Binding","volume":"18","author":"Kazy","year":"2002","journal-title":"World J. Microbiol. Biotechnol."},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/j.jhazmat.2011.01.114","article-title":"Removal of polycyclic aromatic hydrocarbons from aqueous solution using plant residue materials as a biosorbent","volume":"188","author":"Chen","year":"2011","journal-title":"J. Hazard. Mater."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"1","DOI":"10.15666\/aeer\/0502_001009","article-title":"Potencial of Tendu Leaf Refuse for Phenol Removal in Aqueous Systems","volume":"5","author":"Nagda","year":"2007","journal-title":"Appl. Ecol. Environ. Res."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.jhazmat.2010.02.058","article-title":"Study of the removal of paraquat from aqueous solution by biosorption onto Ayous (Triplochiton schleroxylon) sawdust","volume":"179","author":"Dedzo","year":"2010","journal-title":"J. Hazard. Mater."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"16","DOI":"10.4236\/ojopm.2014.41004","article-title":"Study of the Adsorption Efficiency of an Eco-Friendly Carbohydrate Polymer for Contaminated Aqueous Solution by Organophosphorus Pesticide","volume":"4","author":"Abdeen","year":"2014","journal-title":"Open J. Org. Polym. Mater."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.jenvman.2013.04.057","article-title":"Phenanthrene removal from aqueous solutions using well-characterized, raw, chemically treated, and charred malt spent rootlets, a food industry by-product","volume":"128","author":"Valili","year":"2013","journal-title":"J. Environ. Manag."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.marenvres.2013.11.004","article-title":"Vertical distribution of lipids, fatty acids and organochlorine contaminants in the blubber of southern hemisphere humpback whales (Megaptera novaeangliae)","volume":"94","author":"Waugh","year":"2014","journal-title":"Mar. Environ. Res."},{"key":"ref_92","first-page":"302","article-title":"Egyptian Apricot Stone (Prunus armeniaca) as a Low Cost and Eco-friendly Biosorbent for Oxamyl Removal from Aqueous Solutions","volume":"4","author":"Ahmed","year":"2014","journal-title":"Am. J. Exp. Agric."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1007\/s10646-009-0402-6","article-title":"Implications of differences between temperate and tropical freshwater ecosystems for the ecological risk assessment of pesticides","volume":"19","author":"Daam","year":"2010","journal-title":"Ecotoxicology"},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/j.envsci.2006.08.002","article-title":"Agriculture, pesticides, food security and food safety","volume":"9","author":"Carvalho","year":"2006","journal-title":"Environ. Sci. Policy"},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.jenvman.2018.07.039","article-title":"Distribution of cyanobacteria and their interactions with pesticides in paddy field: A comprehensive review","volume":"224","author":"Singh","year":"2018","journal-title":"J. Environ. Manag."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/j.foodpol.2012.06.003","article-title":"Agricultural pesticides and land use intensification in high, middle and low income countries","volume":"37","author":"Schreinemachers","year":"2012","journal-title":"Food Policy"},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"2847","DOI":"10.1897\/06-048.1","article-title":"Survey of carbamate and organophosphorous pesticide export from a south Florida (USA) agricultural watershed: Implications of sampling frequency on ecological risk estimation","volume":"25","author":"Wilson","year":"2006","journal-title":"Environ. Toxicol. Chem."},{"key":"ref_98","unstructured":"World Health Organization (2011). Guidelines for Drinking-Water Quality, World Health Organization."},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.etap.2018.08.018","article-title":"Hazardous effects of chemical pesticides on human health\u2013Cancer and other associated disorders","volume":"63","author":"Sabarwal","year":"2018","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"ref_100","doi-asserted-by":"crossref","unstructured":"Li, Z., and Jennings, A. (2017). Worldwide Regulations of Standard Values of Pesticides for Human Health Risk Control: A Review. Int. J. Environ. Res. Public Health, 14.","DOI":"10.3390\/ijerph14070826"},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.tox.2010.11.008","article-title":"Comparative study of human and mouse pregnane X receptor agonistic activity in 200 pesticides using in vitro reporter gene assays","volume":"280","author":"Kojima","year":"2011","journal-title":"Toxicology"},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"25768","DOI":"10.1038\/srep25768","article-title":"Exposure to organochlorine pesticides and non-Hodgkin lymphoma: A meta-analysis of observational studies","volume":"6","author":"Luo","year":"2016","journal-title":"Sci. Rep."},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1038\/bjc.1987.234","article-title":"Risk of malignant lymphoma in Swedish pesticide appliers","volume":"56","author":"Wiklund","year":"1987","journal-title":"Br. J. Cancer"},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.envint.2017.07.001","article-title":"Environmental exposure to pesticides and the risk of Parkinson\u2019s disease in the Netherlands","volume":"107","author":"Brouwer","year":"2017","journal-title":"Environ. Int."},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1136\/oemed-2013-101394","article-title":"The association between ambient exposure to organophosphates and Parkinson\u2019s disease risk","volume":"71","author":"Wang","year":"2014","journal-title":"Occup. Environ. Med."},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.envres.2013.09.001","article-title":"Long-term exposure to organochlorine pesticides and thyroid status in adults in a heavily contaminated area in Brazil","volume":"127","author":"Freire","year":"2013","journal-title":"Environ. Res."},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.toxlet.2014.09.020","article-title":"P-glycoprotein inhibition by the agricultural pesticide propiconazole and its hydroxylated metabolites: Implications for pesticide\u2013drug interactions","volume":"232","author":"Mazur","year":"2015","journal-title":"Toxicol. Lett."},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"199","DOI":"10.13031\/2013.8432","article-title":"Current Health Effects of Agricultural Work: Respiratory Disease, Cancer, Reproductive Effects, Musculoskeletal Injuries, and Pesticide\u2013Related Illnesses","volume":"8","author":"Kirkhorn","year":"2002","journal-title":"J. Agric. Saf. Health"},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.fct.2013.05.057","article-title":"Glyphosate induces human breast cancer cells growth via estrogen receptors","volume":"59","author":"Thongprakaisang","year":"2013","journal-title":"Food Chem. Toxicol."},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1093\/oxfordjournals.aje.a115031","article-title":"A case-control study of brain gliomas and occupational exposure to chemical carcinogens: The risk to farmers","volume":"128","author":"Musicco","year":"1988","journal-title":"Am. J. Epidemiol."},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1038\/250528a0","article-title":"EPA halts dieldrin production","volume":"250","author":"Norman","year":"1974","journal-title":"Nature"},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"2399","DOI":"10.1002\/cncr.27941","article-title":"Agent Orange as a risk factor for high-grade prostate cancer","volume":"119","author":"Ansbaugh","year":"2013","journal-title":"Cancer"},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1023\/A:1008828600164","article-title":"The Effects of Carbaryl Exposure of the Penultimate Larval Instars of Xathocnemis Zealandica on Emergence and Fluctuating Asymmetry","volume":"7","author":"Hardersen","year":"1998","journal-title":"Ecotoxicology"},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"2152","DOI":"10.1016\/j.procbio.2011.08.015","article-title":"Changes in fatty acid profile and antioxidant systems in a Nostoc muscorum strain exposed to the herbicide bentazon","volume":"46","author":"Galhano","year":"2011","journal-title":"Process. Biochem."},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1104\/pp.114.239061","article-title":"Natural Compounds as Next-Generation Herbicides","volume":"166","author":"Dayan","year":"2014","journal-title":"Plant Physiol."},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1002\/ps.2333","article-title":"Why have no new herbicide modes of action appeared in recent years?","volume":"68","author":"Duke","year":"2012","journal-title":"Pest Manag. Sci."},{"key":"ref_117","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.jfluchem.2012.11.008","article-title":"Synthesis of diversely fluorinated pyrazoles as novel active agrochemical ingredients","volume":"152","author":"Giornal","year":"2013","journal-title":"J. Fluor. Chem."},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1002\/ps.1829","article-title":"The unique role of halogen substituents in the design of modern agrochemicals","volume":"66","author":"Jeschke","year":"2010","journal-title":"Pest Manag. Sci."},{"key":"ref_119","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S1872-0358(06)02004-5","article-title":"Chapter 4 Fluorine-Containing Agrochemicals: An Overview of Recent Developments","volume":"2","author":"Theodoridis","year":"2006","journal-title":"Adv. Fluor. Sci."},{"key":"ref_120","unstructured":"MacDougall, P. (2019, February 25). Agri-Service Report. Available online: https:\/\/www.spglobal.com\/en\/."},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1039\/B711844A","article-title":"Understanding organofluorine chemistry. An introduction to the C\u2013F bond","volume":"37","year":"2008","journal-title":"Chem. Soc. Rev."},{"key":"ref_122","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1002\/cbic.200300801","article-title":"Organic Fluorine: Odd Man Out","volume":"5","author":"Dunitz","year":"2004","journal-title":"Chembiochem"},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1002\/ps.1429","article-title":"Molecular characterisation of resistance to ALS-inhibiting herbicides in Hordeum leporinum biotypes","volume":"63","author":"Yu","year":"2007","journal-title":"Pest Manag. Sci."},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1002\/ps.1860","article-title":"Auxin herbicides: Current status of mechanism and mode of action","volume":"66","author":"Grossmann","year":"2009","journal-title":"Pest Manag. Sci."},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1111\/j.1467-7652.2006.00179.x","article-title":"Characterization of a higher plant herbicide-resistant phytoene desaturase and its use as a selectable marker","volume":"4","author":"Arias","year":"2006","journal-title":"Plant Biotechnol. J."},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1002\/ps.1022","article-title":"Molecular evolution of herbicide resistance to phytoene desaturase inhibitors in Hydrilla verticillata and its potential use to generate herbicide-resistant crops","volume":"61","author":"Arias","year":"2005","journal-title":"Pest Manag. Sci."},{"key":"ref_127","doi-asserted-by":"crossref","unstructured":"B\u00f6ger, P., and Wakabayashi, K. (1999). Peroxidizing Herbicides, Springer.","DOI":"10.1007\/978-3-642-58633-0"},{"key":"ref_128","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1002\/(SICI)1526-4998(200006)56:6<497::AID-PS169>3.0.CO;2-W","article-title":"Towards the Primary Target of Chloroacetamides -New Findings Pave the Way","volume":"56","author":"Matthes","year":"2000","journal-title":"Pest Manag. Sci."},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"6837","DOI":"10.1007\/s00253-016-7504-x","article-title":"Characterization of a novel oxyfluorfen-degrading bacterial strain Chryseobacterium aquifrigidense and its biochemical degradation pathway","volume":"100","author":"Zhao","year":"2016","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"ref_130","unstructured":"ECHA (2022). Annexes II, III, IV, VII\u2014Defined & Temporary Maximum Residue Levels, ECHA."},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"7960","DOI":"10.1007\/s11356-019-04251-w","article-title":"Toxicological impact of oxyfluorfen 24% herbicide on the reproductive system, antioxidant enzymes, and endocrine disruption of Biomphalaria alexandrina (Ehrenberg, 1831) snails","volume":"26","author":"Ibrahim","year":"2019","journal-title":"Environ. Sci. Pollut. Res."},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1104\/pp.86.2.619","article-title":"Studies on the Mode of Action of Acifluorfen-Methyl in Nonchlorophyllous Soybean Cells: Accumulation of Tetrapyrroles","volume":"86","author":"Matringe","year":"1988","journal-title":"Plant Physiol."},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1042\/bj2600231","article-title":"Protoporphyrinogen oxidase as a molecular target for diphenyl ether herbicides","volume":"260","author":"Matringe","year":"1989","journal-title":"Biochem. J."},{"key":"ref_134","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1104\/pp.90.4.1239","article-title":"Inhibition of Plant Protoporphyrinogen Oxidase by the Herbicide Acifluorfen-Methyl","volume":"90","author":"Witkowski","year":"1989","journal-title":"Plant Physiol."},{"key":"ref_135","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1104\/pp.100.3.1211","article-title":"Mode of Action Studies on a Chiral Diphenyl Ether Peroxidizing Herbicide: Correlation between Differential Inhibition of Protoporphyrinogen IX Oxidase Activity and Induction of Tetrapyrrole Accumulation by the Enantiomers","volume":"100","author":"Hallahan","year":"1992","journal-title":"Plant Physiol."},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1017\/S0043174500073239","article-title":"Protoporphyrinogen Oxidase-Inhibiting Herbicides","volume":"39","author":"Duke","year":"1991","journal-title":"Weed Sci."},{"key":"ref_137","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1515\/znc-1990-0535","article-title":"Recent Advances in the Mode of Action of Diphenyl Ethers and Related Herbicides","volume":"45","author":"Scalla","year":"1990","journal-title":"Z. F\u00fcr Nat. C"},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1042\/bj2770017","article-title":"Kinetic studies on protoporphyrinogen oxidase inhibition by diphenyl ether herbicides","volume":"277","author":"Camadro","year":"1991","journal-title":"Biochem. J."},{"key":"ref_139","doi-asserted-by":"crossref","unstructured":"Mance, G. (1987). Pollution Threat of Heavy Metals in Aquatic Environments, Springer.","DOI":"10.1007\/978-94-009-3421-4"},{"key":"ref_140","unstructured":"El-Rayis, O.A., Abouldahab, O., Halim, Y., and Riley, J.P. (, January 21\u201323). Levels of Trace Metals in Some Food Chain Organisms from El-Mex Bay, West of Alexandria, Egypt. Proceedings of the 7th International Conference: Environment Protection is a Must, Alexandria University and USPD, Alexandria, Egypt."},{"key":"ref_141","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1093\/icesjms\/fsm183","article-title":"Assessment of seawater pollution by heavy metals in the neighbourhood of Algiers: Use of the sea urchin, Paracentrotus lividus, as a bioindicator","volume":"65","author":"Soualili","year":"2008","journal-title":"ICES J. Mar. Sci."},{"key":"ref_142","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1242\/jeb.94.1.317","article-title":"Cellular Discrimination Processes in Metal Accumulating Cells","volume":"94","author":"Simkiss","year":"1981","journal-title":"J. Exp. Biol."},{"key":"ref_143","first-page":"57","article-title":"Physico-chemical aspects of inorganic element transfer through membranes","volume":"294","author":"Williams","year":"1981","journal-title":"Philos. Trans. R. Soc. B Biol. Sci."},{"key":"ref_144","first-page":"185","article-title":"Heavy Metals and Biochemical Composition of Four Sea Bream Species (Acanthopagrus Schlegelii Bleeker, Pagrus Major Temminck & Schlegel, Oplegnathus Fasciatus Kr\u00f8yer and Girella Punctata Gray)","volume":"95","author":"Bae","year":"2012","journal-title":"Philipp. Agric. Sci."},{"key":"ref_145","unstructured":"Cajaraville, M.P. (1995). Cell Biology in Environment Toxicology, Universidade del Pais Vasco."},{"key":"ref_146","unstructured":"Chang, W. (1996). Toxicology of Metals, LCRC Lewis Publishers."},{"key":"ref_147","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/BF00397816","article-title":"Toxicity of cupric lon to eggs of the spot Leiostomus xanthurus and the Atlantic silverside Menidia menidia","volume":"50","author":"Engel","year":"1979","journal-title":"Mar. Biol."},{"key":"ref_148","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.scitotenv.2015.09.045","article-title":"Metal fate and effects in estuaries: A review and conceptual model for better understanding of toxicity","volume":"541","author":"Spencer","year":"2016","journal-title":"Sci. Total Environ."},{"key":"ref_149","doi-asserted-by":"crossref","first-page":"6255","DOI":"10.1016\/j.scitotenv.2009.09.004","article-title":"Effects of experimental CO2 leakage on solubility and transport of seven trace metals in seawater and sediment","volume":"407","author":"Ardelan","year":"2009","journal-title":"Sci. Total. Environ."},{"key":"ref_150","doi-asserted-by":"crossref","first-page":"72","DOI":"10.5670\/oceanog.2009.98","article-title":"Effect of Ocean Acidification on the Speciation of Metals in Seawater","volume":"22","author":"Millero","year":"2009","journal-title":"Oceanography"},{"key":"ref_151","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1007\/s11356-010-0338-7","article-title":"Influence of sediment acidification on the bioaccumulation of metals in Ruditapes philippinarum","volume":"17","author":"Kalman","year":"2010","journal-title":"Environ. Sci. Pollut. Res."},{"key":"ref_152","doi-asserted-by":"crossref","first-page":"299","DOI":"10.2113\/gselements.6.5.299","article-title":"Use of Thermodynamics in Examining the Effects of Ocean Acidification","volume":"6","author":"Millero","year":"2010","journal-title":"Elements"},{"key":"ref_153","doi-asserted-by":"crossref","first-page":"2561","DOI":"10.5194\/bg-6-2561-2009","article-title":"Effects of increased pCO2 and temperature on trace element (Ag, Cd and Zn) bioaccumulation in the eggs of the common cuttlefish, Sepia officinalis","volume":"6","author":"Martin","year":"2009","journal-title":"Biogeosciences"},{"key":"ref_154","doi-asserted-by":"crossref","first-page":"2201","DOI":"10.1016\/j.marpolbul.2010.08.018","article-title":"The toxicological interaction between ocean acidity and metals in coastal meiobenthic copepods","volume":"60","author":"Pascal","year":"2010","journal-title":"Mar. Pollut. Bull."},{"key":"ref_155","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.aquatox.2013.05.019","article-title":"Short-term acute hypercapnia affects cellular responses to trace metals in the hard clams Mercenaria mercenaria","volume":"140\u2013141","author":"Ivanina","year":"2013","journal-title":"Aquat. Toxicol."},{"key":"ref_156","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/BF00401287","article-title":"Effects of temperature, nutritive and metal stressors on the reproductive biology of Mytilus edulis","volume":"67","author":"Myint","year":"1982","journal-title":"Mar. Biol."},{"key":"ref_157","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.aquatox.2004.06.003","article-title":"Interactive effects of temperature and copper on immunocompetence and disease susceptibility in mussels (Mytilus edulis)","volume":"69","author":"Parry","year":"2004","journal-title":"Aquat. Toxicol."},{"key":"ref_158","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.marpolbul.2004.02.029","article-title":"Distribution of heavy metals in marine bivalves, fish and coastal sediments in the Gulf and Gulf of Oman","volume":"49","author":"Fowler","year":"2004","journal-title":"Mar. Pollut. Bull."},{"key":"ref_159","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.2174\/0929867053764635","article-title":"Metals, Toxicity and Oxidative Stress","volume":"12","author":"Valko","year":"2005","journal-title":"Curr. Med. Chem."},{"key":"ref_160","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1016\/j.biochi.2006.05.013","article-title":"Cadmium toxicity in animal cells by interference with essential metals","volume":"88","author":"Martelli","year":"2006","journal-title":"Biochimie"},{"key":"ref_161","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1242\/jeb.02589","article-title":"Temperature-dependent effects of cadmium and purine nucleotides on mitochondrial aconitase from a marine ectotherm, Crassostrea virginica: A role of temperature in oxidative stress and allosteric enzyme regulation","volume":"210 Pt 1","author":"Cherkasov","year":"2007","journal-title":"J. Exp. Biol."},{"key":"ref_162","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.mito.2009.08.009","article-title":"Cadmium and mitochondria","volume":"9","author":"Cannino","year":"2009","journal-title":"Mitochondrion"},{"key":"ref_163","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.tox.2011.03.001","article-title":"Advances in metal-induced oxidative stress and human disease","volume":"283","author":"Jomova","year":"2011","journal-title":"Toxicology"},{"key":"ref_164","doi-asserted-by":"crossref","first-page":"1666","DOI":"10.1177\/0960327110396535","article-title":"Impact of pesticides residue and heavy metals on lipids and fatty acids composition of some seafoods of Red Sea (KSA)","volume":"30","author":"Moselhy","year":"2011","journal-title":"Hum. Exp. Toxicol."},{"key":"ref_165","first-page":"39","article-title":"Investigation of Body Size Effect on Bioaccumulation Pattern of Cd, Pb and Ni in the Soft Tissue of Rock Oyster Saccostrea Cucullata from Laft Port Alavian","volume":"4","author":"Petroody","year":"2013","journal-title":"J. Persian Gulf Mar. Sci."},{"key":"ref_166","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1007\/s00244-005-5067-4","article-title":"Biomarkers of Heavy Metal Contamination in the Red Fingered Marsh Crab, Parasesarma erythodactyla","volume":"51","author":"MacFarlane","year":"2006","journal-title":"Arch. Environ. Contam. Toxicol."},{"key":"ref_167","first-page":"301","article-title":"Biological effects of heavy metals: An overview","volume":"26","author":"Sharma","year":"2005","journal-title":"J. Environ. Biol."},{"key":"ref_168","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1006\/ecss.1996.0208","article-title":"Ecophysiology of Trace Metal Uptake in Crustaceans","volume":"44","author":"Rainbow","year":"1997","journal-title":"Estuar. Coast. Shelf Sci."},{"key":"ref_169","unstructured":"Krishnamurti, C.R., and Viswanathan, P. (1991). Toxic Metals in the Indian Environment, Tata McGraw-Hill Limited."},{"key":"ref_170","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S0378-4290(98)00137-3","article-title":"Metals and micronutrients\u2014food safety issues","volume":"60","author":"McLaughlin","year":"1999","journal-title":"Field Crop. Res."},{"key":"ref_171","unstructured":"U.S. Department of Health and Human Services (2004). Toxicological Profile for Copper, U.S. Department of Health and Human Services."},{"key":"ref_172","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1080\/15287394.2019.1624235","article-title":"Genotoxicity assessment of polluted urban streams using a native fish Astyanax altiparanae","volume":"82","author":"Francisco","year":"2019","journal-title":"J. Toxicol. Environ. Health Part A"},{"key":"ref_173","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1080\/15287394.2013.853223","article-title":"Pesticide Residues, Heavy Metals, and DNA Damage in Sentinel Oysters Crassostrea Gigas From Sinaloa and Sonora, Mexico","volume":"77","author":"Mercier","year":"2014","journal-title":"J. Toxicol. Environ. Health Part A"},{"key":"ref_174","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.aquatox.2018.12.019","article-title":"Effects of polluted seawater on oxidative stress, mortality, and reproductive parameters in the marine rotifer Brachionus koreanus and the marine copepod Tigriopus japonicus","volume":"208","author":"Jeong","year":"2018","journal-title":"Aquat. Toxicol."},{"key":"ref_175","first-page":"335","article-title":"Effects of zinc on lipids of erythrocytes from carp (Cyprinus carpio L.) acclimated to different temperatures","volume":"127","author":"Gabryelak","year":"2000","journal-title":"Comp. Biochem. Physiol. Part C Pharmacol. Toxicol. Endocrinol."},{"key":"ref_176","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1023\/A:1014311521708","article-title":"Growth, survival, and metal content of marsh invertebrates fed diets of detritus from Spartina alterniflora Loisel. and Phragmites australis Cav. Trin. ex Steud. from metal-contaminated and clean sites","volume":"10","author":"Weis","year":"2002","journal-title":"Wetl. Ecol. Manag."},{"key":"ref_177","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1016\/j.marpolbul.2008.03.026","article-title":"Copper toxicity in the marine copepod Tigropus japonicus: Low variability and high reproducibility of repeated acute and life-cycle tests","volume":"57","author":"Kwok","year":"2008","journal-title":"Mar. Pollut. Bull."},{"key":"ref_178","unstructured":"Petersen, R.C. (1986). Community Toxicity Testing, ASTM International."},{"key":"ref_179","unstructured":"Luoma, S.N., and Rainbow, P.S. (2008). Metal Contamination in Aquatic Environments: Science and Lateral Management, Cambridge University Press."},{"key":"ref_180","first-page":"448","article-title":"Copper & biological health","volume":"128","author":"Krupanidhi","year":"2008","journal-title":"Indian J. Med. Res."},{"key":"ref_181","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1016\/j.chemosphere.2012.05.075","article-title":"Short-term exposure of the European sea bass Dicentrarchus labrax to copper-based antifouling treated nets: Copper bioavailability and biomarkers responses","volume":"89","author":"Cotou","year":"2012","journal-title":"Chemosphere"},{"key":"ref_182","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1080\/00103624.2013.874022","article-title":"Interactive Effect of Soil Salinity and Copper Application on Growth and Chemical Composition of Pistachio Seedlings (cv. Badami)","volume":"45","author":"Eskandari","year":"2014","journal-title":"Commun. Soil Sci. Plant Anal."},{"key":"ref_183","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/j.jnutbio.2005.01.007","article-title":"Diabetes and dietary copper alter 67Cu metabolism and oxidant defense in the rat","volume":"16","author":"Rucker","year":"2005","journal-title":"J. Nutr. Biochem."},{"key":"ref_184","doi-asserted-by":"crossref","unstructured":"Barman, T.E. (1974). Enzyme Handbook, Springer.","DOI":"10.1007\/978-3-662-11691-3"},{"key":"ref_185","doi-asserted-by":"crossref","first-page":"2397","DOI":"10.1002\/etc.5620201035","article-title":"Biotic ligand model of the acute toxicity of metals. 2. application to acute copper toxicity in freshwater fish and daphnia","volume":"20","author":"Santore","year":"2001","journal-title":"Environ. Toxicol. Chem."},{"key":"ref_186","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.jmarsys.2005.07.004","article-title":"Distribution of total dissolved and C18 extractable copper and nickel in relation to dissolved organic matter sources, in the Thermaikos Gulf (eastern Mediterranean)","volume":"58","author":"Zeri","year":"2005","journal-title":"J. Mar. Syst."},{"key":"ref_187","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1080\/08927010903216564","article-title":"The environmental fate and effects of antifouling paint biocides","volume":"26","author":"Thomas","year":"2010","journal-title":"Biofouling"},{"key":"ref_188","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0300-483X(03)00159-8","article-title":"Copper toxicity, oxidative stress, and antioxidant nutrients","volume":"189","author":"Gaetke","year":"2003","journal-title":"Toxicology"},{"key":"ref_189","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/0742-8413(90)90168-9","article-title":"Heavy metal effects on lipid peroxidation in the tissues of mytilus gallopro vincialis lam","volume":"97","author":"Viarengo","year":"1990","journal-title":"Comp. Biochem. Physiol. Part C Comp. Pharmacol."},{"key":"ref_190","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1080\/13547500500264660","article-title":"Do metals inhibit acetylcholinesterase (AChE)? Implementation of assay conditions for the use of AChE activity as a biomarker of metal toxicity","volume":"10","author":"Frasco","year":"2005","journal-title":"Biomarkers"},{"key":"ref_191","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1006\/fsim.1995.0025","article-title":"Effects of chronic copper exposure on the macrophage chemiluminescent response and gill histology in goldfish (Carassius auratus L.)","volume":"5","author":"Muhvich","year":"1995","journal-title":"Fish Shellfish. Immunol."},{"key":"ref_192","first-page":"261","article-title":"In vitro and in vivo effects of heavy metals on mussel digestive gland hexokinase activity: The role of glutathione","volume":"120","author":"Canesi","year":"1998","journal-title":"Comp. Biochem. Physiol. Part C Pharmacol. Toxicol. Endocrinol."},{"key":"ref_193","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/j.marpolbul.2004.02.020","article-title":"Protective effect of phospholipid hydroperoxide glutathione peroxidase (PHGPx) against lipid peroxidation in mussels Perna perna exposed to different metals","volume":"49","author":"Miyamoto","year":"2004","journal-title":"Mar. Pollut. Bull."},{"key":"ref_194","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0166-445X(97)00024-6","article-title":"Antioxidant enzymes, glutathione and lipid peroxidation as relevant biomarkers of experimental or field exposure in the gills and the digestive gland of the freshwater bivalve Unio tumidus","volume":"39","author":"Doyotte","year":"1997","journal-title":"Aquat. Toxicol."},{"key":"ref_195","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.cbpc.2011.02.004","article-title":"Antioxidant and lipid peroxidation responses in Mytilus galloprovincialis exposed to mixtures of benzo(a)pyrene and copper","volume":"154","author":"Maria","year":"2011","journal-title":"Comp. Biochem. Physiol. C Toxicol. Pharmacol."},{"key":"ref_196","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1002\/etc.5620170626","article-title":"Ecological risk assessment of copper and cadmium in surface waters of Chesapeake Bay watershed","volume":"17","author":"Hall","year":"1998","journal-title":"Environ. Toxicol. Chem."},{"key":"ref_197","doi-asserted-by":"crossref","first-page":"89","DOI":"10.3354\/meps285089","article-title":"Responses of polychaete Hydroides elegans life stages to copper stress","volume":"285","author":"Xie","year":"2005","journal-title":"Mar. Ecol. Prog. Ser."},{"key":"ref_198","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1111\/j.1472-4642.2007.00430.x","article-title":"Pollution reduces native diversity and increases invader dominance in marine hard-substrate communities","volume":"14","author":"Piola","year":"2008","journal-title":"Divers. Distrib."},{"key":"ref_199","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.marpolbul.2015.11.040","article-title":"Contaminant cocktails: Interactive effects of fertiliser and copper paint on marine invertebrate recruitment and mortality","volume":"102","author":"Lawes","year":"2016","journal-title":"Mar. Pollut. Bull."},{"key":"ref_200","doi-asserted-by":"crossref","first-page":"114","DOI":"10.17126\/joralres.2013.026","article-title":"Antimicrobial evaluation of copper sulfate (II) on strains of Enterococcus faecalis. In vitro study","volume":"2","author":"Sierra","year":"2013","journal-title":"J. Oral Res."},{"key":"ref_201","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1111\/jwas.12113","article-title":"The Efficacy of Copper Sulfate in Controlling Infection of Saprolegnia parasitica","volume":"45","author":"Sun","year":"2014","journal-title":"J. World Aquac. Soc."},{"key":"ref_202","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.matlet.2013.01.041","article-title":"A sonochemical technology for coating of textiles with antibacterial nanoparticles and equipment for itsimplementation","volume":"96","author":"Abramova","year":"2013","journal-title":"Mater. Lett."},{"key":"ref_203","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/j.colsurfb.2012.07.002","article-title":"Synthesis and evaluation of antioxidant and antibacterial behavior of CuO nanoparticles","volume":"101","author":"Das","year":"2013","journal-title":"Colloids Surfaces B Biointerfaces"},{"key":"ref_204","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1016\/j.envpol.2011.04.020","article-title":"Responses of a soil bacterium, Pseudomonas chlororaphis O6 to commercial metal oxide nanoparticles compared with responses to metal ions","volume":"159","author":"Geng","year":"2011","journal-title":"Environ. Pollut."},{"key":"ref_205","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.matlet.2014.05.059","article-title":"Template-free hydrothermal method for the synthesis of multi-walled CuO nanotubes","volume":"130","author":"Kaya","year":"2014","journal-title":"Mater. Lett."},{"key":"ref_206","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/j.jmst.2013.04.020","article-title":"Flower-shaped CuO Nanostructures: Synthesis, Characterization and Antimicrobial Activity","volume":"29","author":"Mageshwari","year":"2013","journal-title":"J. Mater. Sci. Technol."},{"key":"ref_207","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.physe.2012.10.019","article-title":"Synthesis of hierarchical CuO microspheres: Photocatalytic and antibacterial activities","volume":"47","author":"Sathyamoorthy","year":"2013","journal-title":"Phys. E Low Dimens. Syst. Nanostructures"},{"key":"ref_208","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.saa.2014.01.080","article-title":"Synthesis and characterization of CuO\u2013montmorillonite nanocomposite by thermal decomposition method and antibacterial activity of nanocomposite","volume":"125","author":"Sohrabnezhad","year":"2014","journal-title":"Spectrochim. Acta Part A Mol. Biomol. Spectrosc."},{"key":"ref_209","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.spmi.2013.10.020","article-title":"Effect of NaOH concentration on structural, surface and antibacterial activity of CuO nanorods synthesized by direct sonochemical method","volume":"66","author":"Sonia","year":"2014","journal-title":"Superlattices Microstruct."},{"key":"ref_210","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.aquatox.2005.05.007","article-title":"Determination of photosynthetic and enzymatic biomarkers sensitivity used to evaluate toxic effects of copper and fludioxonil in alga Scenedesmus obliquus","volume":"74","author":"Dewez","year":"2005","journal-title":"Aquat. Toxicol."},{"key":"ref_211","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.matlet.2014.04.056","article-title":"Antimicrobial activity of sputtered nanocrystalline CuO impregnated fabrics","volume":"128","author":"Subramanian","year":"2014","journal-title":"Mater. Lett."},{"key":"ref_212","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1007\/s10646-015-1505-x","article-title":"Pesticidal activity of metal oxide nanoparticles on plant pathogenic isolates of Pythium","volume":"24","author":"Zabrieski","year":"2015","journal-title":"Ecotoxicology"},{"key":"ref_213","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.micres.2014.08.008","article-title":"Investigation of microbial community structure of a shallow lake after one season copper sulfate algaecide treatment","volume":"170","author":"Song","year":"2015","journal-title":"Microbiol. Res."},{"key":"ref_214","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.cropro.2014.05.004","article-title":"Efficacy and environmental fate of copper sulphate applied to Australian rice fields for control of the aquatic snail Isidorella newcombi","volume":"63","author":"Stevens","year":"2014","journal-title":"Crop. Prot."},{"key":"ref_215","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.hal.2008.11.005","article-title":"Prevention and control of Karenia brevis blooms","volume":"8","author":"Sengco","year":"2009","journal-title":"Harmful Algae"},{"key":"ref_216","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.ecoenv.2015.08.010","article-title":"Histopathological changes in snail, Pomacea canaliculata, exposed to sub-lethal copper sulfate concentrations","volume":"122","author":"Dummee","year":"2015","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"ref_217","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.conbuildmat.2012.11.010","article-title":"The combined effects of copper sulfate and rosin sizing agent treatment on some physical and mechanical properties of poplar wood","volume":"40","author":"Nguyen","year":"2013","journal-title":"Constr. Build. Mater."},{"key":"ref_218","first-page":"453","article-title":"Chloramine and Copper Sulphate as Control Agents of Planktonic Larvae of Chironomus Luridus in Water Supply Systems","volume":"15","author":"Halpern","year":"1999","journal-title":"J. Am. Mosq. Control. Assoc."},{"key":"ref_219","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1080\/15222055.2016.1146183","article-title":"Use of Copper Sulfate to Control Egg Saprolegniasis at a Commercial Sunshine Bass Hatchery","volume":"78","author":"Straus","year":"2016","journal-title":"N. Am. J. Aquac."},{"key":"ref_220","doi-asserted-by":"crossref","unstructured":"Amorim, M.J.B. (2016). The Daunting Challenge of Ensuring Sustainable Development of Nanomaterials. Int. J. Environ. Res. Public Health, 13.","DOI":"10.3390\/ijerph13020245"},{"key":"ref_221","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.3762\/bjnano.6.181","article-title":"Nanotechnology in the real world: Redeveloping the nanomaterial consumer products inventory","volume":"6","author":"Vance","year":"2015","journal-title":"Beilstein J. Nanotechnol."},{"key":"ref_222","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.aquatox.2011.10.005","article-title":"Effects of sediment-associated copper to the deposit-feeding snail, Potamopyrgus antipodarum: A comparison of Cu added in aqueous form or as nano- and micro-CuO particles","volume":"106\u2013107","author":"Pang","year":"2012","journal-title":"Aquat. Toxicol."},{"key":"ref_223","doi-asserted-by":"crossref","first-page":"1976","DOI":"10.1002\/etc.2639","article-title":"Bioaccumulation and effects of different-shaped copper oxide nanoparticles in the deposit-feeding snail Potamopyrgus antipodarum","volume":"33","author":"Ramskov","year":"2014","journal-title":"Environ. Toxicol. Chem."},{"key":"ref_224","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.impact.2017.05.003","article-title":"Comparative environmental fate and toxicity of copper nanomaterials","volume":"7","author":"Keller","year":"2017","journal-title":"Nanoimpact"},{"key":"ref_225","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/S0025-326X(96)00172-5","article-title":"\u2018Oyster watch\u2019: Monitoring trace metal and organochlorine concentrations in Sydney\u2019s coastal waters","volume":"33","author":"Scanes","year":"1996","journal-title":"Mar. Pollut. Bull."},{"key":"ref_226","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.marpolbul.2011.01.012","article-title":"Antifouling strategies: History and regulation, ecological impacts and mitigation","volume":"62","author":"Dafforn","year":"2011","journal-title":"Mar. Pollut. Bull."},{"key":"ref_227","doi-asserted-by":"crossref","first-page":"2137","DOI":"10.1016\/j.marpolbul.2011.07.009","article-title":"Bearing the burden of boat harbours: Heavy contaminant and fouling loads in a native habitat-forming alga","volume":"62","author":"Johnston","year":"2011","journal-title":"Mar. Pollut. Bull."},{"key":"ref_228","unstructured":"WHO (2022). Guidelines for Drinking-Water Quality: Fourth Edition Incorporating the First and Second Addenda, WHO."},{"key":"ref_229","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1002\/etc.4663","article-title":"Bioaccumulation and Toxicity of Cadmium, Copper, Nickel, and Zinc and Their Mixtures to Aquatic Insect Communities","volume":"39","author":"Mebane","year":"2020","journal-title":"Environ. Toxicol. Chem."},{"key":"ref_230","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S1546-5098(11)31002-3","article-title":"Copper","volume":"31","author":"Grosell","year":"2011","journal-title":"Fish Physiol."},{"key":"ref_231","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1111\/j.1399-3054.1978.tb01651.x","article-title":"Inhibition of Photosystem II in the Green Alga Ankistrodesmus falcatus by Copper","volume":"44","author":"Shioi","year":"1978","journal-title":"Physiol. Plant."},{"key":"ref_232","first-page":"429","article-title":"Heavy metal-induced inhibition of photosynthesis: Targets of in vivo heavy metal chlorophyll formation","volume":"38","author":"Spiller","year":"2002","journal-title":"J. Phycol."},{"key":"ref_233","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.marpolbul.2016.06.011","article-title":"A limited legacy effect of copper in marine biofilms","volume":"109","author":"McElroy","year":"2016","journal-title":"Mar. Pollut. Bull."},{"key":"ref_234","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1007\/s00244-001-0007-4","article-title":"Embryo-Larval Toxicity Tests with the African Catfish (Clarias gariepinus): Comparative Sensitivity of Endpoints","volume":"42","author":"Nguyen","year":"2002","journal-title":"Arch. Environ. Contam. Toxicol."}],"container-title":["International Journal of Environmental Research and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1660-4601\/20\/4\/3706\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T18:36:39Z","timestamp":1760121399000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1660-4601\/20\/4\/3706"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,19]]},"references-count":234,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2023,2]]}},"alternative-id":["ijerph20043706"],"URL":"https:\/\/doi.org\/10.3390\/ijerph20043706","relation":{},"ISSN":["1660-4601"],"issn-type":[{"value":"1660-4601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,19]]}}}