{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T14:34:02Z","timestamp":1771338842832,"version":"3.50.1"},"reference-count":105,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2018,8,10]],"date-time":"2018-08-10T00:00:00Z","timestamp":1533859200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>In this critical review, plant sources used as effective antibacterial agents against Helicobacter pylori infections are carefully described. The main intrinsic bioactive molecules, responsible for the observed effects are also underlined and their corresponding modes of action specifically highlighted. In addition to traditional uses as herbal remedies, in vitro and in vivo studies focusing on plant extracts and isolated bioactive compounds with anti-H. pylori activity are also critically discussed. Lastly, special attention was also given to plant extracts with urease inhibitory effects, with emphasis on involved modes of action.<\/jats:p>","DOI":"10.3390\/ijms19082361","type":"journal-article","created":{"date-parts":[[2018,8,10]],"date-time":"2018-08-10T10:52:01Z","timestamp":1533898321000},"page":"2361","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":81,"title":["Phytochemicals in Helicobacter pylori Infections: What Are We Doing Now?"],"prefix":"10.3390","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6900-9797","authenticated-orcid":false,"given":"Bahare","family":"Salehi","sequence":"first","affiliation":[{"name":"Medical Ethics and Law Research Center, Shahid Beheshti University of Medical Sciences, Tehran 88777539, Iran"},{"name":"Student Research Committee, Shahid Beheshti University of Medical Sciences, Tehran 22439789, Iran"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0378-8887","authenticated-orcid":false,"given":"Farukh","family":"Sharopov","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Technology, Avicenna Tajik State Medical University, Rudaki 139, Dushanbe 734003, Tajikistan"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3183-7623","authenticated-orcid":false,"given":"Miquel","family":"Martorell","sequence":"additional","affiliation":[{"name":"Nutrition and Dietetics Department, Faculty of Pharmacy, University of Concepci\u00f3n, Concepci\u00f3n, 4070386 VIII\u2013Bio Bio Region, Chile"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6173-2219","authenticated-orcid":false,"given":"Jovana","family":"Rajkovic","sequence":"additional","affiliation":[{"name":"Institute of Pharmacology, Clinical Pharmacology and Toxicology, Medical Faculty, University of Belgrade, 11129 Belgrade, Serbia"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8325-1304","authenticated-orcid":false,"given":"Adedayo Oluwaseun","family":"Ademiluyi","sequence":"additional","affiliation":[{"name":"Functional Foods, Nutraceuticals and Phytomedicine Unit, Department of Biochemistry, Federal University of Technology, Akure 340252, Nigeria"}]},{"given":"Mehdi","family":"Sharifi-Rad","sequence":"additional","affiliation":[{"name":"Department of Medical Parasitology, Zabol University of Medical Sciences, Zabol 61663335, Iran"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3724-3527","authenticated-orcid":false,"given":"Patrick Valere Tsouh","family":"Fokou","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Faculty of Science, University of Yaounde 1, Yaounde P.O. Box 812, Cameroon"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5934-5201","authenticated-orcid":false,"given":"Nat\u00e1lia","family":"Martins","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Porto, Alameda Prof. Hern\u00e2ni Monteiro, 4200-319 Porto, Portugal"},{"name":"Institute for Research and Innovation in Health (i3S), University of Porto, 4200-135 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5063-1236","authenticated-orcid":false,"given":"Marcello","family":"Iriti","sequence":"additional","affiliation":[{"name":"Department of Agricultural and Environmental Sciences, Milan State University, via G. 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