{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T19:06:43Z","timestamp":1772824003394,"version":"3.50.1"},"reference-count":38,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2024,4,13]],"date-time":"2024-04-13T00:00:00Z","timestamp":1712966400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia (FCT) through COMPETE Programme (Operational Programme for Competitiveness)","award":["UIDB\/QUI\/00313\/2020"],"award-info":[{"award-number":["UIDB\/QUI\/00313\/2020"]}]},{"name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia (FCT) through COMPETE Programme (Operational Programme for Competitiveness)","award":["UIDB\/00285\/2020"],"award-info":[{"award-number":["UIDB\/00285\/2020"]}]},{"name":"FCT\u2014Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","award":["UIDB\/QUI\/00313\/2020"],"award-info":[{"award-number":["UIDB\/QUI\/00313\/2020"]}]},{"name":"FCT\u2014Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","award":["UIDB\/00285\/2020"],"award-info":[{"award-number":["UIDB\/00285\/2020"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>In this work, we propose a comprehensive experimental study of the diffusion of nickel ions in combination with different cyclodextrins as carrier molecules for enhanced solubility and facilitated transport. For this, ternary mutual diffusion coefficients measured by Taylor dispersion method are reported for aqueous solutions containing nickel salts and different cyclodextrins (that is, \u03b1-CD, \u03b2-CD, and \u03b3-CD) at 298.15 K. A combination of Taylor dispersion and other methods, such as UV-vis spectroscopy, will be used to obtain complementary information on these systems. The determination of the physicochemical properties of these salts with CDs in aqueous solution provides information that allows us to understand solute\u2013solvent interactions, and gives a significant contribution to understanding the mechanisms underlying diffusional transport in aqueous solutions, and, consequently, to mitigating the potential toxicity associated with these metal ions. For example, using mutual diffusion data, it is possible to estimate the number of moles of each ion transported per mole of the cyclodextrin driven by its own concentration gradient.<\/jats:p>","DOI":"10.3390\/ijms25084328","type":"journal-article","created":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T10:24:26Z","timestamp":1713176666000},"page":"4328","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Transport Properties in Multicomponent Systems Containing Cyclodextrins and Nickel Ions"],"prefix":"10.3390","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9145-3184","authenticated-orcid":false,"given":"S\u00f3nia I. G.","family":"Fangaia","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Institute of Implantology and Prosthodontics, University of Coimbra, 3000-075 Coimbra, Portugal"},{"name":"Center for Innovation and Research in Oral Sciences (CIROS), Faculty of Medicine, University of Coimbra, 3000-075 Coimbra, Portugal"},{"name":"CQC, Department of Chemistry, University of Coimbra, 3004-535 Coimbra, Portugal"}]},{"given":"Daniela S. A.","family":"Silva","sequence":"additional","affiliation":[{"name":"CQC, Department of Chemistry, University of Coimbra, 3004-535 Coimbra, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4019-9379","authenticated-orcid":false,"given":"Ana","family":"Messias","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Institute of Implantology and Prosthodontics, University of Coimbra, 3000-075 Coimbra, Portugal"},{"name":"Center of Mechanical Engineering Materials and Processes (CEMMPRE), Departamento de Engenharia Mec\u00e2nica, University of Coimbra, 3030-788 Coimbra, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7900-4482","authenticated-orcid":false,"given":"Pedro M. G.","family":"Nicolau","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Institute of Implantology and Prosthodontics, University of Coimbra, 3000-075 Coimbra, Portugal"},{"name":"Center for Innovation and Research in Oral Sciences (CIROS), Faculty of Medicine, University of Coimbra, 3000-075 Coimbra, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4612-7686","authenticated-orcid":false,"given":"Artur J. M.","family":"Valente","sequence":"additional","affiliation":[{"name":"CQC, Department of Chemistry, University of Coimbra, 3004-535 Coimbra, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9787-0843","authenticated-orcid":false,"given":"M. Melia","family":"Rodrigo","sequence":"additional","affiliation":[{"name":"Universidad de Alcal\u00e1, Departamento de Qu\u00edmica Anal\u00edtica, Qu\u00edmica F\u00edsica e Ingenier\u00eda Qu\u00edmica, 28805 Alcal\u00e1 de Henares, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3005-1963","authenticated-orcid":false,"given":"Ana C. F.","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"CQC, Department of Chemistry, University of Coimbra, 3004-535 Coimbra, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2024,4,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2756","DOI":"10.1039\/b718436k","article-title":"Selectively Functionalized Cyclodextrins and Their Metal Complexes","volume":"38","author":"Bellia","year":"2009","journal-title":"Chem. Soc. 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