{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T00:43:58Z","timestamp":1759970638147,"version":"build-2065373602"},"reference-count":35,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T00:00:00Z","timestamp":1737676800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Italian Ministry of the University and the Research","award":["2021RTDA46_02B2_DMIF","DOT215B2RJ"],"award-info":[{"award-number":["2021RTDA46_02B2_DMIF","DOT215B2RJ"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>The study of solid\u2013liquid equilibria offers critical insights into the molecular interactions between constituents in binary mixtures. Predicting these equilibria often requires comprehensive thermodynamic models, yet simplified approaches can provide valuable perspectives. In this work, we explore the application of the Bragg\u2013Williams model to solid\u2013liquid equilibria in binary mixtures leading to the formation of eutectic solvents. This model relies on a single parameter\u2014the molar energy change upon mixing compounds\u2014and demonstrates noteworthy features: the parameter can be estimated from a few (in principle, from a single) experimental melting points, and it correlates strongly with interaction energy parameters from more complex models, such as the PC-SAFT molecular-based equation of state. By using the Bragg\u2013Williams model, we provide a straightforward and informative framework for characterizing solid\u2013liquid equilibria, enabling insights into molecular interactions while requiring few data points as input. Despite its simplicity, the model effectively captures the essence of binary mixture energetics, positioning it as a practical tool for advancing the understanding of phase behavior in eutectic solvent systems.<\/jats:p>","DOI":"10.3390\/ijms26030997","type":"journal-article","created":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T08:48:23Z","timestamp":1737708503000},"page":"997","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Single-Parameter Bragg\u2013Williams Model for Eutectic Solvents"],"prefix":"10.3390","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2023-339X","authenticated-orcid":false,"given":"Ozge","family":"Ozkilinc","sequence":"first","affiliation":[{"name":"Dipartimento di Scienze Matematiche, Informatiche e Fisiche (DMIF), University of Udine, 33100 Udine, Italy"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5780-9949","authenticated-orcid":false,"given":"Miguel Angel","family":"Soler","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze Matematiche, Informatiche e Fisiche (DMIF), University of Udine, 33100 Udine, Italy"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9635-3227","authenticated-orcid":false,"given":"Paolo","family":"Giannozzi","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze Matematiche, Informatiche e Fisiche (DMIF), University of Udine, 33100 Udine, Italy"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9996-2426","authenticated-orcid":false,"given":"Santiago","family":"Aparicio","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Burgos, 09001 Burgos, Spain"},{"name":"International Research Center in Critical Raw Materials for Advanced Industrial Technologies (ICCRAM), University of Burgos, 09001 Burgos, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9862-250X","authenticated-orcid":false,"given":"Federico","family":"Fogolari","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze Matematiche, Informatiche e Fisiche (DMIF), University of Udine, 33100 Udine, Italy"}]}],"member":"1968","published-online":{"date-parts":[[2025,1,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"9142","DOI":"10.1021\/ja048266j","article-title":"Deep eutectic solvents formed between choline chloride and carboxylic acids: Versatile alternatives to ionic liquids","volume":"126","author":"Abbott","year":"2004","journal-title":"J. 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