{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:17:45Z","timestamp":1760059065018,"version":"build-2065373602"},"reference-count":30,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2025,5,17]],"date-time":"2025-05-17T00:00:00Z","timestamp":1747440000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCDD"],"abstract":"<jats:p>Background: Aortic valve stenosis remains the most prevalent valvular pathology in Western countries. Rapid deployment bioprosthesis (RD) has emerged as a promising alternative to conventional valves for surgical aortic valve replacement (SAVR), particularly in elderly and high-risk patients. This study reports the short- and long-term outcomes of RD in patients with isolated aortic stenosis. Methods: A retrospective single-center analysis was conducted on 382 patients who underwent RD-AVR between 2014 and 2020. Data were collected from clinical files and national electronic databases. Primary outcomes included cardiopulmonary bypass (CPB) and cross-clamping (XC) times, postoperative complications, and long-term survival. Results: The mean age was 75.6 \u00b1 5.9 years, with 29.8% of patients over 80 years old and a mean EuroSCORE II of 2.3 \u00b1 1.5%. CPB and XC times were 36.7 \u00b1 10.8 and 27.4 \u00b1 8.1 min, respectively. Postoperative complications included acute kidney injury (AKI, 53.4%), de novo atrial fibrillation (31.9%), and high-grade\/complete atrioventricular block with permanent pacemaker implantation (9.8%). In-hospital and 30-day mortality was 1.02% and 2.3%, respectively. The 5-year survival rate was 77%. At 6 months postoperatively, the mean transvalvular gradient was 11.1 \u00b1 4.7 mmHg. At a median follow-up of 6.7 years, no cases of structural valve deterioration and only one case of endocarditis were reported. Conclusion: In this single-center study, RD in isolated AVR demonstrated favorable short- and long-term outcomes, including no structural valve deterioration at mid-term follow-up. These devices offer a safe and effective alternative to conventional SAVR, particularly in high-risk populations.<\/jats:p>","DOI":"10.3390\/jcdd12050191","type":"journal-article","created":{"date-parts":[[2025,5,19]],"date-time":"2025-05-19T05:37:13Z","timestamp":1747633033000},"page":"191","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Isolated Rapid Deployment Aortic Valve Replacement in Patients with Aortic Stenosis: Single-Center Retrospective Study"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0084-3916","authenticated-orcid":false,"given":"Ricardo","family":"Ferreira","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery, Hospital de Santa Maria, Unidade Local de Sa\u00fade Santa Maria, 1649-035 Lisbon, Portugal"},{"name":"Centro Cardiovascular da Universidade de Lisboa (CCUL@RISE), Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisbon, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0455-8189","authenticated-orcid":false,"given":"Tiago R.","family":"Velho","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Hospital de Santa Maria, Unidade Local de Sa\u00fade Santa Maria, 1649-035 Lisbon, Portugal"},{"name":"Centro Cardiovascular da Universidade de Lisboa (CCUL@RISE), Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisbon, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1656-1561","authenticated-orcid":false,"given":"Jo\u00e3o","family":"Gon\u00e7alves","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Hospital de Santa Maria, Unidade Local de Sa\u00fade Santa Maria, 1649-035 Lisbon, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2278-7505","authenticated-orcid":false,"given":"Andr\u00e9","family":"Sena","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Hospital de Santa Maria, Unidade Local de Sa\u00fade Santa Maria, 1649-035 Lisbon, Portugal"}]},{"given":"Beatriz","family":"Draiblate","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Hospital de Santa Maria, Unidade Local de Sa\u00fade Santa Maria, 1649-035 Lisbon, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0360-4363","authenticated-orcid":false,"given":"Ana G.","family":"Almeida","sequence":"additional","affiliation":[{"name":"Centro Cardiovascular da Universidade de Lisboa (CCUL@RISE), Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisbon, Portugal"},{"name":"Department of Cardiology, Hospital de Santa Maria, Unidade Local de Sa\u00fade Santa Maria, 1649-035 Lisbon, Portugal"}]},{"given":"\u00c2ngelo","family":"Nobre","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Hospital de Santa Maria, Unidade Local de Sa\u00fade Santa Maria, 1649-035 Lisbon, Portugal"},{"name":"Centro Cardiovascular da Universidade de Lisboa (CCUL@RISE), Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisbon, Portugal"}]},{"given":"Fausto","family":"Pinto","sequence":"additional","affiliation":[{"name":"Centro Cardiovascular da Universidade de Lisboa (CCUL@RISE), Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisbon, Portugal"},{"name":"Department of Cardiology, Hospital de Santa Maria, Unidade Local de Sa\u00fade Santa Maria, 1649-035 Lisbon, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2025,5,17]]},"reference":[{"key":"ref_1","unstructured":"(2024, August 16). 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