{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:29:26Z","timestamp":1760146166736,"version":"build-2065373602"},"reference-count":52,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2024,10,5]],"date-time":"2024-10-05T00:00:00Z","timestamp":1728086400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Egas Moniz Center for Interdisciplinary Research","award":["UIDB\/04585\/2020","UIDB\/00214\/2020"],"award-info":[{"award-number":["UIDB\/04585\/2020","UIDB\/00214\/2020"]}]},{"name":"Center of Linguistics of the University of Lisbon","award":["UIDB\/04585\/2020","UIDB\/00214\/2020"],"award-info":[{"award-number":["UIDB\/04585\/2020","UIDB\/00214\/2020"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Aim: We aimed to explore whether there is an association between maternal perceived infant discomfort due to suggestive gastrointestinal alterations and oral-health-related quality of life (OHRQoL) through a survey. Materials and Methods: The present study included two main phases involving Portuguese-speaking parents with full-term infants aged 2\u201312 weeks old who were not previously hospitalized in a neonatal nursery. First, the original French Infant Colic Questionnaire (ColiQ) was translated, cross-culturally adapted and validated to Portuguese (ColiQ-PT). Then, a survey was distributed, and included sociodemographics, the ColiQ-PT, an oral health value scale, OHRQoL, self-perceived periodontal status, and smoking and oral health habits. Data were analyzed through inferential, correlation and multivariate logistic models in this cross-sectional study. Results: The ColiQ-PT revealed reliability and validity. From a total of 421 responses, higher infant discomfort was correlated with less maternal professional dental care prioritization (\u03c1 = \u22120.096, p &lt; 0.05). Self-perceived periodontitis correlated with all items of OHRQoL (p &lt; 0.001), all seven OHIP-14 domains, and with the physical (p &lt; 0.001), psychological (p = 0.006), and social (p = 0.011) super-domains. While the infant-related score was associated with baby age (p = 0.023) and physical pain (p = 0.040) related to OHRQoL, the parent score was associated with education (p = 0.005), unemployment (p = 0.035), and physical pain (p = 0.017). The total ColiQ-PT score was significantly associated with more deteriorated social disability related to maternal OHRQoL (\u03c1 = \u22120.130, p &lt; 0.05). Conclusions: Perceived infant discomfort seems to be linked to maternal deteriorated OHRQoL. This finding highlights the importance of prioritizing oral health in postpartum care. Further research is needed to explore the mechanisms underlying this association and to develop targeted interventions.<\/jats:p>","DOI":"10.3390\/jcm13195931","type":"journal-article","created":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T07:30:18Z","timestamp":1728286218000},"page":"5931","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Perceived Infant Discomfort Linked to Lower Maternal Oral Health Quality of Life: Results from a Cross-Sectional Study"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-2788-5672","authenticated-orcid":false,"given":"Lisetty","family":"Garrido","sequence":"first","affiliation":[{"name":"Egas Moniz Interdisciplinary Research Center (CiiEM), Egas Moniz School of Health and Science, 2829-511 Almada, Portugal"}]},{"given":"In\u00eas","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Egas Moniz Interdisciplinary Research Center (CiiEM), Egas Moniz School of Health and Science, 2829-511 Almada, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6804-9124","authenticated-orcid":false,"given":"Patr\u00edcia","family":"Lyra","sequence":"additional","affiliation":[{"name":"Egas Moniz Interdisciplinary Research Center (CiiEM), Egas Moniz School of Health and Science, 2829-511 Almada, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8482-5936","authenticated-orcid":false,"given":"Lu\u00eds","family":"Proen\u00e7a","sequence":"additional","affiliation":[{"name":"Egas Moniz Interdisciplinary Research Center (CiiEM), Egas Moniz School of Health and Science, 2829-511 Almada, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1019-8263","authenticated-orcid":false,"given":"Jo\u00e3o","family":"Botelho","sequence":"additional","affiliation":[{"name":"Egas Moniz Interdisciplinary Research Center (CiiEM), Egas Moniz School of Health and Science, 2829-511 Almada, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6102-0772","authenticated-orcid":false,"given":"S\u00f3nia","family":"Frota","sequence":"additional","affiliation":[{"name":"Center of Linguistics, School of Arts and Humanities, University of Lisbon, 1600-214 Lisboa, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0167-4077","authenticated-orcid":false,"given":"Jos\u00e9 Jo\u00e3o","family":"Mendes","sequence":"additional","affiliation":[{"name":"Egas Moniz Interdisciplinary Research Center (CiiEM), Egas Moniz School of Health and Science, 2829-511 Almada, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2503-260X","authenticated-orcid":false,"given":"Vanessa","family":"Machado","sequence":"additional","affiliation":[{"name":"Egas Moniz Interdisciplinary Research Center (CiiEM), Egas Moniz School of Health and Science, 2829-511 Almada, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2024,10,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1053\/j.gastro.2016.02.016","article-title":"Childhood Functional Gastrointestinal Disorders: Neonate\/Toddler","volume":"150","author":"Benninga","year":"2016","journal-title":"Gastroenterology"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Campeotto, F., Barbaza, M.-O., and Hospital, V. (2020). Functional Gastrointestinal Disorders in Outpatients Aged up to 12 Months: A French Non-Interventional Study. Int. J. Environ. Res. Public Health, 17.","DOI":"10.3390\/ijerph17114031"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1016\/j.jpeds.2014.11.039","article-title":"Prevalence of Functional Gastrointestinal Disorders in Infants and Toddlers","volume":"166","author":"Hyman","year":"2015","journal-title":"J. Pediatr."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Chandran, D., Warren, K., McKeone, D., and Hicks, S.D. (2023). The Association between Infant Colic and the Multi-Omic Composition of Human Milk. Biomolecules, 13.","DOI":"10.3390\/biom13030559"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"e015418","DOI":"10.1136\/bmjopen-2016-015418","article-title":"Developing a Core Outcome Set for Infant Colic for Primary, Secondary and Tertiary Care Settings: A Prospective Study","volume":"7","author":"Steutel","year":"2017","journal-title":"BMJ Open"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.arcped.2021.02.018","article-title":"Assessment of the Severity of Infant Crying and Its Impact on Parents: Development and Validation of the ColiQ Questionnaire in France","volume":"28","author":"Bellaiche","year":"2021","journal-title":"Arch. P\u00e9diatrie"},{"key":"ref_7","unstructured":"WHO (2010). Technical Consultation on Postpartum and Postnatal Care, World Health Organization."},{"key":"ref_8","first-page":"1","article-title":"Alanazi Relationship between Health Related Quality of Life Determinants and Type of Delivery in Saudi Women","volume":"4","author":"AlShehri","year":"2015","journal-title":"Fam. Med. Med. Sci. Res."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1586\/erp.09.8","article-title":"In Search of Health: Quality of Life among Postpartum Palestinian Women","volume":"9","author":"Hammoudeh","year":"2009","journal-title":"Expert Rev. Pharmacoeconomics Outcomes Res."},{"key":"ref_10","first-page":"15","article-title":"A Comparison of Taiwanese and American Breastfeeding Mothers\u2019 Self-Reported Problems at Three Weeks Postpartum","volume":"13","author":"Ko","year":"2015","journal-title":"Fu-Jen J. Med."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"2455","DOI":"10.1111\/apa.15873","article-title":"Distress in Fathers of Babies with Infant Colic","volume":"110","author":"Veldhuis","year":"2021","journal-title":"Acta Paediatr."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"2352","DOI":"10.1111\/apa.16550","article-title":"Impact of the COVID -19 Pandemic on Mental Health in Parents of Infants with Colic and on Healthcare Use","volume":"111","author":"Hartjes","year":"2022","journal-title":"Acta Paediatr."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1111\/apa.14348","article-title":"Multiple Functional Gastrointestinal Disorders Are Frequent in Formula-Fed Infants and Decrease Their Quality of Life","volume":"107","author":"Bellaiche","year":"2018","journal-title":"Acta Paediatr."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"207","DOI":"10.5223\/pghn.2019.22.3.207","article-title":"Functional Gastrointestinal Disorders in Infancy: Impact on the Health of the Infant and Family","volume":"22","author":"Vandenplas","year":"2019","journal-title":"Pediatr. Gastroenterol. Hepatol. Nutr."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/S0140-6736(19)31146-8","article-title":"Oral Diseases: A Global Public Health Challenge","volume":"394","author":"Peres","year":"2019","journal-title":"Lancet"},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Barranca-Enr\u00edquez, A., and Romo-Gonz\u00e1lez, T. (2022). Your Health Is in Your Mouth: A Comprehensive View to Promote General Wellness. Front. Oral. Health, 3.","DOI":"10.3389\/froh.2022.971223"},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Machado, V., Botelho, J., Proen\u00e7a, L., Alves, R., Oliveira, M.J., Amaro, L., \u00c1guas, A., and Mendes, J.J. (2020). Periodontal Status, Perceived Stress, Diabetes Mellitus and Oral Hygiene Care on Quality of Life: A Structural Equation Modelling Analysis. BMC Oral Health, 20.","DOI":"10.1186\/s12903-020-01219-y"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"867","DOI":"10.2471\/BLT.07.045120","article-title":"For the STROBE Initiative The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: Guidelines for Reporting Observational Studies","volume":"85","author":"Altman","year":"2007","journal-title":"Bull. World Health Organ."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.jclinepi.2006.03.012","article-title":"Quality Criteria Were Proposed for Measurement Properties of Health Status Questionnaires","volume":"60","author":"Terwee","year":"2007","journal-title":"J. Clin. Epidemiol."},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Machado, V., Mendon\u00e7a, A., Proen\u00e7a, L., Mendes, J.J., Botelho, J., McNeill, D.W., and Delgado, A.S. (2022). Cross-Cultural Adaptation and Validation of the Oral Health Values Scale for the Portuguese Population. J. Pers. Med., 12.","DOI":"10.3390\/jpm12050672"},{"key":"ref_21","doi-asserted-by":"crossref","unstructured":"Machado, V., Lyra, P., Santos, C., Proen\u00e7a, L., Mendes, J.J., and Botelho, J. (2022). Self-Reported Measures of Periodontitis in a Portuguese Population: A Validation Study. J. Pers. Med., 12.","DOI":"10.3390\/jpm12081315"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"374","DOI":"10.15309\/17psd180208","article-title":"Oral health-related quality of life: Portuguese linguistic and cultural adaptation of OHIP-14","volume":"18","author":"Afonso","year":"2017","journal-title":"Psicol Sa\u00fade Doen\u00e7a"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1111\/cdoe.12621","article-title":"Development and Validation of the Oral Health Values Scale","volume":"49","author":"Edwards","year":"2021","journal-title":"Comm. Dent. Oral Epid."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"104253","DOI":"10.1016\/j.jdent.2022.104253","article-title":"Prevalence of Periodontal Disease in Pregnancy: A Systematic Review and Meta-Analysis","volume":"125","author":"Chen","year":"2022","journal-title":"J. Dent."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Machado, V., Ferreira, M., Lopes, L., Mendes, J.J., and Botelho, J. (2023). Adverse Pregnancy Outcomes and Maternal Periodontal Disease: An Overview on Meta-Analytic and Methodological Quality. J. Clin. Med., 12.","DOI":"10.2139\/ssrn.4372959"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1111\/jcpe.12517","article-title":"Are Periodontal Diseases Really Silent? A Systematic Review of Their Effect on Quality of Life","volume":"43","author":"Buset","year":"2016","journal-title":"J. Clin. Periodontol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"4014","DOI":"10.2174\/1381612826666200523171639","article-title":"Oral Health-Related Quality of Life during Pregnancy: A Systematic Review","volume":"26","author":"Fakheran","year":"2020","journal-title":"Curr. Pharm. Des."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"423","DOI":"10.17219\/dmp\/125028","article-title":"Impact of Periodontitis on the Oral Health Impact Profile: A Systematic Review and Meta-Analysis","volume":"57","author":"Konopka","year":"2020","journal-title":"Dent. Med. Probl."},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Vasiliou, A., Shankardass, K., Nisenbaum, R., and Qui\u00f1onez, C. (2016). Current Stress and Poor Oral Health. BMC Oral Health, 16.","DOI":"10.1186\/s12903-016-0284-y"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1055\/s-0039-1693507","article-title":"Association between Psychological Stress and Periodontitis: A Systematic Review","volume":"14","author":"Castro","year":"2020","journal-title":"Eur. J. Dent."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00784-019-03089-3","article-title":"The Assessment of Stress, Depression, and Inflammation as a Collective Risk Factor for Periodontal Diseases: A Systematic Review","volume":"24","author":"Decker","year":"2020","journal-title":"Clin. Oral Investig."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"3479","DOI":"10.1007\/s00784-023-04956-w","article-title":"Effect of Psychosocial Stress and Coping Strategies on Non-Surgical Periodontal Therapy in Patients with Generalized Stage III\/IV Periodontitis: A Longitudinal Intervention Study","volume":"27","author":"Romano","year":"2023","journal-title":"Clin. Oral Investig."},{"key":"ref_33","doi-asserted-by":"crossref","unstructured":"De Abreu, M.H.N.G., Cruz, A.J.S., Borges-Oliveira, A.C., Martins, R.D.C., and Mattos, F.D.F. (2021). Perspectives on Social and Environmental Determinants of Oral Health. Int. J. Environ. Res. Public Health, 18.","DOI":"10.3390\/ijerph182413429"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1007\/s13312-018-1423-0","article-title":"Infantile Colic: An Update","volume":"55","author":"Sarasu","year":"2018","journal-title":"Indian Pediatr."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.jpeds.2017.02.020","article-title":"Systematic Review and Meta-Analysis: Fussing and Crying Durations and Prevalence of Colic in Infants","volume":"185","author":"Wolke","year":"2017","journal-title":"J. Pediatr."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1136\/archdischild-2013-305562","article-title":"Maternal Anxiety Disorders Predict Excessive Infant Crying: A Prospective Longitudinal Study","volume":"99","author":"Petzoldt","year":"2014","journal-title":"Arch. Dis. Child."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1111\/cch.12292","article-title":"Maternal Anxiety versus Depressive Disorders: Specific Relations to Infants\u2019 Crying, Feeding and Sleeping Problems","volume":"42","author":"Petzoldt","year":"2016","journal-title":"Child"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"e96","DOI":"10.1542\/peds.2008-3100","article-title":"Paternal Depressive Symptoms During Pregnancy Are Related to Excessive Infant Crying","volume":"124","author":"Crijnen","year":"2009","journal-title":"Pediatrics"},{"key":"ref_39","doi-asserted-by":"crossref","unstructured":"Achdut, N., and Refaeli, T. (2020). Unemployment and Psychological Distress among Young People during the COVID-19 Pandemic: Psychological Resources and Risk Factors. Int. J. Environ. Res. Public Health, 17.","DOI":"10.3390\/ijerph17197163"},{"key":"ref_40","doi-asserted-by":"crossref","unstructured":"Majeed, H., Baumann, S., and Majeed, H. (2023). Understanding the Association between County-Level Unemployment and Health Stratified by Education and Income in the Southwestern United States. Sci. Rep., 13.","DOI":"10.1038\/s41598-023-49088-z"},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Norstr\u00f6m, F., Virtanen, P., Hammarstr\u00f6m, A., Gustafsson, P.E., and Janlert, U. (2014). How Does Unemployment Affect Self-Assessed Health? A Systematic Review Focusing on Subgroup Effects. BMC Public Health, 14.","DOI":"10.1186\/1471-2458-14-1310"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1136\/adc.2005.083790","article-title":"Mothers\u2019 Postpartum Psychological Adjustment and Infantile Colic","volume":"91","author":"Akman","year":"2006","journal-title":"Arch. Dis. Child."},{"key":"ref_43","doi-asserted-by":"crossref","unstructured":"Indrio, F., Dargenio, V.N., Francavilla, R., Szajewska, H., and Vandenplas, Y. (2023). Infantile Colic and Long-Term Outcomes in Childhood: A Narrative Synthesis of the Evidence. Nutrients, 15.","DOI":"10.3390\/nu15030615"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1038\/s41575-018-0008-7","article-title":"Infant Colic: Mechanisms and Management","volume":"15","author":"Zeevenhooven","year":"2018","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"245","DOI":"10.3920\/BM2014.0090","article-title":"Preventive Effects of Oral Probiotic on Infantile Colic: A Prospective, Randomised, Blinded, Controlled Trial Using Lactobacillus Reuteri DSM 17938","volume":"6","author":"Savino","year":"2015","journal-title":"Benef. Microbes"},{"key":"ref_46","unstructured":"Brito, A.I.R. (2017). Efeito do choro excessivo na confian\u00e7a materna percebida e na resposta ao sinal de choro do beb\u00e9: Estudo explorat\u00f3rio. [Master\u2019s Thesis, Faculdade de Psicologia e Ci\u00eancias da Educa\u00e7\u00e3o da Universidade de Coimbra (FPCE-UC)]."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1016\/j.jval.2011.06.003","article-title":"Response Burden and Questionnaire Length: Is Shorter Better? A Review and Meta-Analysis","volume":"14","author":"Rolstad","year":"2011","journal-title":"Value Health"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"x64","DOI":"10.1093\/annonc\/mdt474","article-title":"Patient-Reported Outcomes in Ovarian Cancer Clinical Trials","volume":"24","author":"Friedlander","year":"2013","journal-title":"Ann. Oncol."},{"key":"ref_49","first-page":"83","article-title":"Oral Health-Related Quality of Life: What, Why, How, and Future Implications","volume":"212","author":"Sischo","year":"2011","journal-title":"Br. Dent. J."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1093\/pubmed\/fdi031","article-title":"Mode of Questionnaire Administration Can Have Serious Effects on Data Quality","volume":"27","author":"Bowling","year":"2005","journal-title":"J. Public Health"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"S159","DOI":"10.1002\/JPER.18-0006","article-title":"Staging and Grading of Periodontitis: Framework and Proposal of a New Classification and Case Definition","volume":"89","author":"Tonetti","year":"2018","journal-title":"J. Periodontol."},{"key":"ref_52","unstructured":"Kislaya, I., Braz, P., Dias, C.M., and Loureiro, I. (2014). A evolu\u00e7\u00e3o do aleitamento materno em Portugal nas \u00faltimas duas d\u00e9cadas: Dados dos Inqu\u00e9ritos Nacionais de Sa\u00fade. [Bachelor\u2019s Thesis, Universidade Fernando Pessoa]."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/19\/5931\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T16:10:54Z","timestamp":1760112654000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/13\/19\/5931"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,5]]},"references-count":52,"journal-issue":{"issue":"19","published-online":{"date-parts":[[2024,10]]}},"alternative-id":["jcm13195931"],"URL":"https:\/\/doi.org\/10.3390\/jcm13195931","relation":{},"ISSN":["2077-0383"],"issn-type":[{"type":"electronic","value":"2077-0383"}],"subject":[],"published":{"date-parts":[[2024,10,5]]}}}