{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T15:03:57Z","timestamp":1774623837052,"version":"3.50.1"},"reference-count":190,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T00:00:00Z","timestamp":1697414400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Miss\u00e3o Interface"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JFB"],"abstract":"<jats:p>Achieving lightweight, high-strength, and biocompatible composites is a crucial objective in the field of tissue engineering. Intricate porous metallic structures, such as lattices, scaffolds, or triply periodic minimal surfaces (TPMSs), created via the selective laser melting (SLM) technique, are utilized as load-bearing matrices for filled ceramics. The primary metal alloys in this category are titanium-based Ti6Al4V and iron-based 316L, which can have either a uniform cell or a gradient structure. Well-known ceramics used in biomaterial applications include titanium dioxide (TiO2), zirconium dioxide (ZrO2), aluminum oxide (Al2O3), hydroxyapatite (HA), wollastonite (W), and tricalcium phosphate (TCP). To fill the structures fabricated by SLM, an appropriate ceramic is employed through the spark plasma sintering (SPS) method, making them suitable for in vitro or in vivo applications following minor post-processing. The combined SLM-SPS approach offers advantages, such as rapid design and prototyping, as well as assured densification and consolidation, although challenges persist in terms of large-scale structure and molding design. The individual or combined application of SLM and SPS processes can be implemented based on the specific requirements for fabricated sample size, shape complexity, densification, and mass productivity. This flexibility is a notable advantage offered by the combined processes of SLM and SPS. The present article provides an overview of metal\u2013ceramic composites produced through SLM-SPS techniques. Mg-W-HA demonstrates promise for load-bearing biomedical applications, while Cu-TiO2-Ag exhibits potential for virucidal activities. Moreover, a functionally graded lattice (FGL) structure, either in radial or longitudinal directions, offers enhanced advantages by allowing adjustability and control over porosity, roughness, strength, and material proportions within the composite.<\/jats:p>","DOI":"10.3390\/jfb14100521","type":"journal-article","created":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T08:25:09Z","timestamp":1697531109000},"page":"521","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Selective Laser Melting and Spark Plasma Sintering: A Perspective on Functional Biomaterials"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4145-3298","authenticated-orcid":false,"given":"Ramin","family":"Rahmani","sequence":"first","affiliation":[{"name":"CiTin\u2014Centro de Interface Tecnol\u00f3gico Industrial, 4970-786 Arcos de Valdevez, Portugal"},{"name":"proMetheus, Instituto Polit\u00e9cnico de Viana do Castelo (IPVC), 4900-347 Viana do Castelo, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6944-7757","authenticated-orcid":false,"given":"S\u00e9rgio Ivan","family":"Lopes","sequence":"additional","affiliation":[{"name":"CiTin\u2014Centro de Interface Tecnol\u00f3gico Industrial, 4970-786 Arcos de Valdevez, Portugal"},{"name":"ADiT-Lab, Instituto Polit\u00e9cnico de Viana do Castelo (IPVC), 4900-347 Viana do Castelo, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5644-2527","authenticated-orcid":false,"given":"Konda Gokuldoss","family":"Prashanth","sequence":"additional","affiliation":[{"name":"Department of Mechanical and Industrial Engineering, Tallinn University of Technology, 19086 Tallinn, Estonia"},{"name":"CBCMT, School of Mechanical Engineering, Vellore Institute of Technology, Vellore 630014, Tamil Nadu, India"}]}],"member":"1968","published-online":{"date-parts":[[2023,10,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1108\/13552540710776142","article-title":"Selective laser melting of biocompatible metals for rapid manufacturing of medical parts","volume":"13","author":"Vandenbroucke","year":"2007","journal-title":"Rapid Prototyp. J."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"108353","DOI":"10.1016\/j.ijmecsci.2023.108353","article-title":"Selective laser melted Ti6Al4V split-P TPMS lattices for bone tissue engineering","volume":"251","author":"Rezapourian","year":"2023","journal-title":"Int. J. Mech. Sci."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1089\/ten.tec.2008.0288","article-title":"Rapid Prototyping: Porous Titanium Alloy Scaffolds Produced by Selective Laser Melting for Bone Tissue Engineering","volume":"15","author":"Warnke","year":"2009","journal-title":"Tissue Eng. Part C Methods"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.colsurfb.2015.06.074","article-title":"Microsphere-based selective laser sintering for building macroporous bone scaffolds with controlled microstructure and excellent biocompatibility","volume":"135","author":"Du","year":"2015","journal-title":"Colloids Surf. B Biointerfaces"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"6797","DOI":"10.1016\/j.jmrt.2021.11.112","article-title":"Microstructure, shape memory properties, and in vitro biocompatibility of porous NiTi scaffolds fabricated via selective laser melting","volume":"15","author":"Lu","year":"2021","journal-title":"J. Mater. Res. Technol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"5001","DOI":"10.1016\/j.surfcoat.2008.05.003","article-title":"Interface interactions between porous titanium\/tantalum coatings, produced by Selective Laser Melting (SLM), on a cobalt\u2013chromium alloy","volume":"202","author":"Fox","year":"2008","journal-title":"Surf. Coat. Technol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"5700","DOI":"10.3390\/ma6125700","article-title":"Production of Porous \u03b2-Type Ti-40Nb Alloy for Biomedical Applications: Comparison of Selective Laser Melting and Hot Pressing","volume":"6","author":"Zhuravleva","year":"2013","journal-title":"Materials"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/s11106-011-9329-6","article-title":"Selective laser sintering\/melting of nitinol\u2013hydroxyapatite composite for medical applications","volume":"50","author":"Shishkovskii","year":"2011","journal-title":"Powder Metall. Met. Ceram."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Serrano-Aroca, \u00c1. (2022). Antiviral Characterization of Advanced Materials: Use of Bacteriophage Phi 6 as Surrogate of Enveloped Viruses Such as SARS-CoV-2. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms23105335"},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Luo, J.P., Jia, X., Gu, R.N., Zhou, P., Huang, Y.J., Sun, J.F., and Yan, M. (2018). 316L Stainless Steel Manufactured by Selective Laser Melting and Its Biocompatibility with or without Hydroxyapatite Coating. Metals, 8.","DOI":"10.3390\/met8070548"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.jmbbm.2017.04.024","article-title":"Al2O3-Ti functionally graded material prepared by spark plasma sintering for orthopaedic applications","volume":"72","author":"Bahraminasab","year":"2017","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1179\/003258902225007041","article-title":"Spark plasma sintering as advanced PM sintering method","volume":"45","author":"Mamedov","year":"2013","journal-title":"Powder Metall."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"16707","DOI":"10.1016\/j.ceramint.2019.05.151","article-title":"Microstructures and mechanical properties of ZrB2-SiC-Ni ceramic composites prepared by spark plasma sintering","volume":"45","author":"Yan","year":"2019","journal-title":"Ceram. Int."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1002\/adem.201500419","article-title":"Selective Laser Melting of Titanium Alloys and Titanium Matrix Composites for Biomedical Applications: A Review","volume":"18","author":"Zhang","year":"2016","journal-title":"Adv. Eng. Mater."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"111955","DOI":"10.1016\/j.vacuum.2023.111955","article-title":"Deformation behavior of metallic lattice structures with symmetrical gradients of porosity manufactured by metal additive manufacturing","volume":"211","author":"Jagadeesh","year":"2023","journal-title":"Vacuum"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"322","DOI":"10.4028\/www.scientific.net\/AST.63.322","article-title":"The Potential of Spark Plasma Sintering (SPS) Method for the Fabrication on an Industrial Scale of Functionally Graded Materials","volume":"63","author":"Tokita","year":"2010","journal-title":"Adv. Sci. Technol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.prosdent.2014.10.012","article-title":"Clinical marginal and internal fit of metal ceramic crowns fabricated with a selective laser melting technology","volume":"113","author":"Huang","year":"2015","journal-title":"J. Prosthet. Dent."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Baghi, A.D., Nafisi, S., Ebendorff-Heidepriem, H., and Ghomashchi, R. (2022). Microstructural Development of Ti-6Al-4V Alloy via Powder Metallurgy and Laser Powder Bed Fusion. Metals, 12.","DOI":"10.3390\/met12091462"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1016\/j.jmrt.2021.03.043","article-title":"Comparative evaluation of thermal and mechanical properties of nickel alloy 718 prepared using selective laser melting, spark plasma sintering, and casting methods","volume":"12","author":"Hakeem","year":"2021","journal-title":"J. Mater. Res. Technol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"153520","DOI":"10.1016\/j.jallcom.2019.153520","article-title":"Microstructures and mechanical properties of Si and Zr modified Al-Zn-Mg-Cu alloy\u2014A comparison between selective laser melting and spark plasma sintering","volume":"821","author":"Li","year":"2020","journal-title":"J. Alloys Compd."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.promfg.2017.07.148","article-title":"The Role of Additive Manufacturing in the Era of Industry 4.0","volume":"11","author":"Dilberoglu","year":"2017","journal-title":"Procedia Manuf."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1930001","DOI":"10.1142\/S2424862219300011","article-title":"Additive Manufacturing Applications in Industry 4.0: A Review","volume":"4","author":"Haleem","year":"2019","journal-title":"J. Ind. Integr. Manag."},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Chekotu, J.C., Groarke, R., O\u2019toole, K., and Brabazon, D. (2019). Advances in Selective Laser Melting of Nitinol Shape Memory Alloy Part Production. Materials, 12.","DOI":"10.3390\/ma12050809"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1111\/jopr.12268","article-title":"Selective Laser Melting Technique of Co-Cr Dental Alloys: A Review of Structure and Properties and Comparative Analysis with Other Available Techniques","volume":"24","author":"Koutsoukis","year":"2015","journal-title":"J. Prosthodont."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.jallcom.2015.11.141","article-title":"Selective laser melting of titanium alloy with 50 wt% tantalum: Microstructure and mechanical properties","volume":"660","author":"Sing","year":"2016","journal-title":"J. Alloys Compd."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"108514","DOI":"10.1016\/j.matdes.2020.108514","article-title":"The in vitro and in vivo biological effects and osteogenic activity of novel biodegradable porous Mg alloy scaffolds","volume":"189","author":"Wang","year":"2020","journal-title":"Mater. Des."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"102926","DOI":"10.1016\/j.ijplas.2021.102926","article-title":"Selective laser melting of Cu-Ni-Sn: A comprehensive study on the microstructure, mechanical properties, and deformation behavior","volume":"138","author":"Zhao","year":"2021","journal-title":"Int. J. Plast."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1600635","DOI":"10.1002\/adem.201600635","article-title":"Characterization and Comparison of Inconel 625 Processed by Selective Laser Melting and Laser Metal Deposition","volume":"19","author":"Marchese","year":"2016","journal-title":"Adv. Eng. Mater."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"4223","DOI":"10.1007\/s00170-018-1891-3","article-title":"Additive manufacturing of fine-structured copper alloy by selective laser melting of pre-alloyed Cu-15Ni-8Sn powder","volume":"96","author":"Zhang","year":"2018","journal-title":"Int. J. Adv. Manuf. Technol."},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"Rahmani, R., Antonov, M., and Prashanth, K.G. (2021). The impact resistance of highly densified metal alloys manufactured from gas-atomized pre-alloyed powders. Coatings, 11.","DOI":"10.3390\/coatings11020216"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1108\/RPJ-11-2015-0178","article-title":"Direct selective laser sintering and melting of ceramics: A review","volume":"23","author":"Sing","year":"2017","journal-title":"Rapid Prototyp. J."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/j.scriptamat.2013.01.012","article-title":"Photocatalytic activity of spark plasma sintered TiO2\u2013graphene nanoplatelet composite","volume":"68","author":"Zhang","year":"2013","journal-title":"Scr. Mater."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1016\/j.jeurceramsoc.2008.08.025","article-title":"Ceramics for medical applications: A picture for the next 20 years","volume":"29","author":"Chevalier","year":"2009","journal-title":"J. Eur. Ceram. Soc."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1016\/j.ceramint.2014.09.045","article-title":"Application of carbonaceous template for porous structure control of ceramic composites based on synthetic wollastonite obtained via Spark Plasma Sintering","volume":"41","author":"Papynov","year":"2015","journal-title":"Ceram. Int."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.jeurceramsoc.2021.09.023","article-title":"Near-zero-shrinkage Al2O3 ceramic foams with coral-like and hollow-sphere structures via selective laser sintering and reaction bonding","volume":"41","author":"Dong","year":"2021","journal-title":"J. Eur. Ceram. Soc."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.jeurceramsoc.2013.07.023","article-title":"Additive manufacturing of zirconia parts by indirect selective laser sintering","volume":"34","author":"Shahzad","year":"2014","journal-title":"J. Eur. Ceram. Soc."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1016\/j.ijbiomac.2022.07.140","article-title":"Recent advances in 3D-printed polylactide and polycaprolactone-based biomaterials for tissue engineering applications","volume":"218","author":"Arif","year":"2022","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_38","doi-asserted-by":"crossref","unstructured":"Khalid, M.Y., Arif, Z.U., Noroozi, R., Hossain, M., Ramakrishna, S., and Umer, R. (2023). 3D\/4D printing of cellulose nanocrystals-based biomaterials: Additives for sustainable applications. Int. J. Biol. Macromol., 251.","DOI":"10.1016\/j.ijbiomac.2023.126287"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s10856-022-06641-y","article-title":"In vivo biocompatibility evaluation of 3D-printed nickel\u2013titanium fabricated by selective laser melting","volume":"33","author":"Naujokat","year":"2022","journal-title":"J. Mater. Sci. Mater. Med."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.msec.2018.06.024","article-title":"Antibacterial activities and biocompatibilities of Ti-Ag alloys prepared by spark plasma sintering and acid etching","volume":"92","author":"Lei","year":"2018","journal-title":"Mater. Sci. Eng. C"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"161970","DOI":"10.1016\/j.jallcom.2021.161970","article-title":"Yttrium for the selective laser melting of Ti-45Al-8Nb intermetallic: Powder surface structure, laser absorptivity, and printability","volume":"892","author":"Li","year":"2022","journal-title":"J. Alloys Compd."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.actamat.2019.05.008","article-title":"Selective laser melting enabled additive manufacturing of Ti-22Al-25Nb intermetallic: Excellent combination of strength and ductility, and unique microstructural features associated","volume":"173","author":"Zhou","year":"2019","journal-title":"Acta Mater."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/j.jallcom.2016.02.183","article-title":"Microstructural evolution and microhardness of a selective-laser-melted Ti-6Al-4V alloy after post heat treatments","volume":"672","author":"Wu","year":"2016","journal-title":"J. Alloys Compd."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1007\/s00170-019-04002-8","article-title":"Microstructural characterization of binary microstructure pattern in selective laser-melted Ti-6Al-4V","volume":"104","author":"Neikter","year":"2019","journal-title":"Int. J. Adv. Manuf. Technol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"4379","DOI":"10.1007\/s00170-017-0525-5","article-title":"Effects of scanning speed on in vitro biocompatibility of 316L stainless steel parts elaborated by selective laser melting","volume":"92","author":"Shang","year":"2017","journal-title":"Int. J. Adv. Manuf. Technol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.matdes.2018.04.058","article-title":"Bio-functional and anti-corrosive 3D printing 316L stainless steel fabricated by selective laser melting","volume":"152","author":"Kong","year":"2018","journal-title":"Mater. Des."},{"key":"ref_47","doi-asserted-by":"crossref","unstructured":"Konieczny, B., Szczesio-Wlodarczyk, A., Sokolowski, J., and Bociong, K. (2020). Challenges of Co-Cr Alloy Additive Manufacturing Methods in Dentistry\u2014The Current State of Knowledge (Systematic Review). Materials, 13.","DOI":"10.3390\/ma13163524"},{"key":"ref_48","doi-asserted-by":"crossref","unstructured":"Manakari, V., Parande, G., and Gupta, M. (2017). Selective Laser Melting of Magnesium and Magnesium Alloy Powders: A Review. Metals, 7.","DOI":"10.3390\/met7010002"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"163842","DOI":"10.1016\/j.ijleo.2019.163842","article-title":"Research progress on selective laser melting (SLM) of magnesium alloys: A review","volume":"207","author":"Zhang","year":"2020","journal-title":"Optik"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1039\/b715313a","article-title":"Porous biocompatible implants and tissue scaffolds synthesized by selective laser sintering from Ti and NiTi","volume":"18","author":"Shishkovsky","year":"2008","journal-title":"J. Mater. Chem."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/s11517-012-1001-x","article-title":"Selective laser sintering in biomedical engineering","volume":"51","author":"Mazzoli","year":"2013","journal-title":"Med. Biol. Eng. Comput."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.phpro.2012.10.060","article-title":"Direct Selective Laser Melting of Nitinol Powder","volume":"39","author":"Shishkovsky","year":"2012","journal-title":"Phys. Procedia"},{"key":"ref_53","unstructured":"Dar, G.I., Saeed, M., and Wu, A. (2020). Toxicity of TiO2 Nanoparticles, Wiley Online. Chapter 2."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1016\/j.chemosphere.2012.09.013","article-title":"Toxicity of TiO2 nanoparticles to cladocerans, algae, rotifers and plants\u2014Effects of size and crystalline structure","volume":"90","author":"Hurel","year":"2013","journal-title":"Chemosphere"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1093\/toxsci\/kfj140","article-title":"Pulmonary Instillation Studies with Nanoscale TiO2 Rods and Dots in Rats: Toxicity Is not Dependent upon Particle Size and Surface Area","volume":"91","author":"Warheit","year":"2006","journal-title":"Toxicological Sci."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"3626","DOI":"10.1016\/j.fct.2008.09.012","article-title":"Nanotoxicity of TiO2 nanoparticles to erythrocyte in vitro","volume":"46","author":"Li","year":"2008","journal-title":"Food Chem. Toxicol."},{"key":"ref_57","doi-asserted-by":"crossref","unstructured":"Sanches, P.L., Geaquinto, L.R.d.O., Cruz, R., Schuck, D.C., Lorencini, M., Granjeiro, J.M., and Ribeiro, A.R.L. (2020). Toxicity Evaluation of TiO2 Nanoparticles on the 3D Skin Model: A Systematic Review. Front. Bioeng. Biotechnol., 8.","DOI":"10.3389\/fbioe.2020.00575"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"4271","DOI":"10.1016\/j.ceramint.2017.12.008","article-title":"Effects of TiO2 on microstructural, mechanical properties and in-vitro bioactivity of plasma sprayed yttria stabilised zirconia coatings for dental application","volume":"44","author":"Jemat","year":"2018","journal-title":"Ceram. Int."},{"key":"ref_59","doi-asserted-by":"crossref","unstructured":"Ge, R., Xun, C., Yang, J., Jia, W., and Li, Y. (2019). In vivo therapeutic effect of wollastonite and hydroxyapatite on bone defect. Biomed. Mater., 14.","DOI":"10.1088\/1748-605X\/ab4238"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"4065","DOI":"10.1016\/S0142-9612(02)00143-6","article-title":"Plasma sprayed wollastonite\/TiO2 composite coatings on titanium alloys","volume":"23","author":"Liu","year":"2002","journal-title":"Biomaterials"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1016\/j.surfcoat.2016.08.062","article-title":"Structure and properties of the wollastonite\u2013calcium phosphate coatings deposited on titanium and titanium\u2013niobium alloy using microarc oxidation method","volume":"307","author":"Sedelnikova","year":"2016","journal-title":"Surf. Coat. Technol."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.msec.2012.09.008","article-title":"The biocompatibility of dense and porous Nickel\u2013Titanium produced by selective laser melting","volume":"33","author":"Habijan","year":"2013","journal-title":"Mater. Sci. Eng. C"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.aquatox.2014.10.014","article-title":"Toxicity of nano-TiO2 on algae and the site of reactive oxygen species production","volume":"158","author":"Li","year":"2015","journal-title":"Aquat. Toxicol."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.carbpol.2012.08.068","article-title":"TiO2 nanowire and TiO2 nanowire doped Ag-PVP nanocomposite for antimicrobial and self-cleaning cotton textile","volume":"91","author":"Hebeish","year":"2013","journal-title":"Carbohydr. Polym."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1016\/j.chemosphere.2013.06.075","article-title":"Toxicity of TiO2, ZrO2, Fe0, Fe2O3, and Mn2O3 nanoparticles to the yeast, Saccharomyces cerevisiae","volume":"93","author":"Field","year":"2013","journal-title":"Chemosphere"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"112501","DOI":"10.1016\/j.msec.2021.112501","article-title":"A bimetallic load-bearing bioceramics of TiO2@ZrO2 integrated polycaprolactone fibrous tissue construct exhibits anti bactericidal effect and induces osteogenesis in MC3T3-E1 cells","volume":"131","author":"Kandel","year":"2021","journal-title":"Mater. Sci. Eng. C"},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"8305871","DOI":"10.1155\/2020\/8305871","article-title":"Synthesis and Characterization of Hierarchical Mesoporous-Macroporous TiO2-ZrO2 Nanocomposite Scaffolds for Cancellous Bone Tissue Engineering Applications","volume":"2020","author":"Mahtabian","year":"2020","journal-title":"J. Nanomater."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.1016\/j.msec.2012.04.014","article-title":"Effect of ZrO2 addition on the mechanical properties of porous TiO2 bone scaffolds","volume":"32","author":"Tiainen","year":"2012","journal-title":"Mater. Sci. Eng. C"},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.ecoenv.2013.04.004","article-title":"Screening of in vitro cytotoxicity, antioxidant potential and bioactivity of nano- and micro-ZrO2 and -TiO2 particles","volume":"93","author":"Karunakaran","year":"2013","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"ref_70","doi-asserted-by":"crossref","unstructured":"Lyashenko, E.N., Uzbekova, L.D., Polovinkina, V.V., Dorofeeva, A.K., Ibragimov, S.-U.S.-U., Tatamov, A.A., Avkaeva, A.G., Mikhailova, A.A., Tuaeva, I.S., and Esiev, R.K. (2023). Study of the Embryonic Toxicity of TiO2 and ZrO2 Nanoparticles. Micromachines, 14.","DOI":"10.3390\/mi14020363"},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1023\/A:1020305008042","article-title":"Osseointegration and osseoconductivity of hydroxyapatite of different microporosities","volume":"13","author":"Rosa","year":"2002","journal-title":"J. Mater. Sci. Mater. Med."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1016\/j.jeurceramsoc.2016.01.010","article-title":"3D printing magnesium-doped wollastonite\/\u03b2-TCP bioceramics scaffolds with high strength and adjustable degradation","volume":"36","author":"Shao","year":"2016","journal-title":"J. Eur. Ceram. Soc."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1007\/s10856-008-3564-5","article-title":"Study on antibacterial effect of 45S5 Bioglass\u00ae","volume":"20","author":"Hu","year":"2009","journal-title":"J. Mater. Sci. Mater. Med."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1016\/j.msec.2011.07.011","article-title":"In vitro bioactivity and biocompatibility of lithium substituted 45S5 bioglass","volume":"31","author":"Khorami","year":"2011","journal-title":"Mater. Sci. Eng. C"},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.aanat.2013.12.001","article-title":"Comparative study of biphasic calcium phosphate with beta-tricalcium phosphate in rat cranial defects\u2014A molecular-biological and histological study","volume":"199","author":"Scholz","year":"2015","journal-title":"Ann. Anat.\u2014Anat. Anz."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.dib.2016.11.080","article-title":"Biphasic calcium phosphates (BCP) of hydroxyapatite (HA) and tricalcium phosphate (TCP) as bone substitutes: Importance of physicochemical characterizations in biomaterials studies","volume":"10","author":"Ebrahimi","year":"2021","journal-title":"Data Brief"},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"239","DOI":"10.4028\/www.scientific.net\/KEM.799.239","article-title":"3D Printing of Plain and Gradient Cermets with Efficient Use of Raw Materials","volume":"799","author":"Antonov","year":"2019","journal-title":"Key Eng. Mater."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1177\/0885328216657271","article-title":"Recent advances in research on magnesium alloys and magnesium\u2013calcium phosphate composites as biodegradable implant materials","volume":"31","author":"Basista","year":"2017","journal-title":"J. Biomater. Appl."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1098\/rsif.2009.0559","article-title":"Development of magnesium calcium phosphate biocement for bone regeneration","volume":"7","author":"Jia","year":"2010","journal-title":"J. R. Soc. Interface"},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.jmapro.2022.09.056","article-title":"Selective laser melting of in-situ CoCrFeMnNi high entropy alloy: Effect of remelting","volume":"84","author":"Karimi","year":"2022","journal-title":"J. Manuf. Process."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"101465","DOI":"10.1016\/j.mtla.2022.101465","article-title":"Hybrid metal-ceramic biomaterials fabricated through powder bed fusion and powder metallurgy for improved impact resistance of craniofacial implants","volume":"24","author":"Rahmani","year":"2022","journal-title":"Materialia"},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.jmbbm.2014.12.015","article-title":"Relationship between unit cell type and porosity and the fatigue behavior of selective laser melted meta-biomaterials","volume":"43","author":"Yavari","year":"2015","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"191","DOI":"10.3176\/proc.2019.2.11","article-title":"Modelling of impact-abrasive wear of ceramic, metallic, and composite materials","volume":"68","author":"Rahmani","year":"2019","journal-title":"Proc. Estonian Acad. Sci."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"2327","DOI":"10.1016\/j.actbio.2011.01.037","article-title":"Osteoinduction of porous Ti implants with a channel structure fabricated by selective laser melting","volume":"7","author":"Fukuda","year":"2011","journal-title":"Acta Biomater."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.apsusc.2013.11.069","article-title":"Crystal structure and nanotopographical features on the surface of heat-treated and anodized porous titanium biomaterials produced using selective laser melting","volume":"290","author":"Yavari","year":"2014","journal-title":"Appl. Surf. Sci."},{"key":"ref_86","doi-asserted-by":"crossref","unstructured":"Egan, D.S., and Dowling, D.P. (2020). Correlating in-situ process monitoring data with the reduction in load bearing capacity of selective laser melted Ti-6Al-4V porous biomaterials. J. Mech. Behav. Biomed. Mater., 106.","DOI":"10.1016\/j.jmbbm.2020.103723"},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1080\/17452759.2016.1142215","article-title":"The effect of laser energy input on the microstructure, physical and mechanical properties of Ti-6Al-4V alloys by selective laser melting","volume":"11","author":"Do","year":"2016","journal-title":"Virtual Phys. Prototyp."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1080\/17452751003688368","article-title":"On the effect of scanning strategies in the selective laser melting process","volume":"5","author":"Jhabvala","year":"2010","journal-title":"Virtual Phys. Prototyp."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1080\/17452759.2015.1026045","article-title":"Evaluation of residual stress in stainless steel 316L and Ti6Al4V samples produced by selective laser melting","volume":"10","author":"Yadroitsev","year":"2015","journal-title":"Virtual Phys. Prototyp."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1002\/adem.201300409","article-title":"Field-Assisted Sintering Technology\/Spark Plasma Sintering: Mechanisms, Materials, and Technology Developments","volume":"16","author":"Guillon","year":"2014","journal-title":"Adv. Eng. Mater."},{"key":"ref_91","doi-asserted-by":"crossref","unstructured":"Cavaliere, P., Sadeghi, B., and Shabani, A. (2019). Spark Plasma Sintering of Materials: Advances in Processing and Applications, Springer.","DOI":"10.1007\/978-3-030-05327-7"},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.1111\/j.1151-2916.2002.tb00381.x","article-title":"Spark Plasma Sintering of Alumina","volume":"85","author":"Shen","year":"2002","journal-title":"J. Am. Ceram. Soc."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1016\/j.msec.2019.04.064","article-title":"Review on titanium and titanium based alloys as biomaterials for orthopaedic applications","volume":"102","author":"Kaur","year":"2019","journal-title":"Mater. Sci. Eng. C"},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.jmbbm.2015.02.023","article-title":"Fabrication, pore structure and compressive behavior of anisotropic porous titanium for human trabecular bone implant applications","volume":"46","author":"Li","year":"2015","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"107105","DOI":"10.1016\/j.intermet.2021.107105","article-title":"Ti-based bulk metallic glass implantable biomaterial with adjustable porosity produced by a novel pressure regulation method in spark plasma sintering","volume":"131","author":"Wu","year":"2021","journal-title":"Intermetallics"},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1016\/j.bioeng.2007.08.008","article-title":"Spark plasma sintering synthesis of porous nanocrystalline titanium alloys for biomedical applications","volume":"24","author":"Nicula","year":"2007","journal-title":"Biomol. Eng."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1002\/(SICI)1097-4636(19971205)37:3<394::AID-JBM10>3.0.CO;2-C","article-title":"Human osteoblast-like cells (MG63) proliferate on a bioactive glass surface","volume":"37","author":"Price","year":"1997","journal-title":"J. Biomed. Mater. Res."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.vacuum.2015.09.024","article-title":"Mechanical behaviors of porous Ti with high porosity and large pore size prepared by one-step spark plasma sintering technique","volume":"122","author":"Zhang","year":"2015","journal-title":"Vacuum"},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"24691","DOI":"10.1016\/j.ceramint.2019.08.208","article-title":"Novel silicon-wollastonite based scaffolds for bone tissue engineering produced by selective laser melting","volume":"45","author":"Kamboj","year":"2019","journal-title":"Ceram. Int."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/0021-9290(85)90287-8","article-title":"The mechanical behaviour of cancellous bone","volume":"18","author":"Gibson","year":"1985","journal-title":"J. Biomech."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1016\/j.jallcom.2016.04.176","article-title":"Production of porous Ti5Al2.5Fe alloy via pressureless spark plasma sintering","volume":"680","author":"Yamanoglu","year":"2016","journal-title":"J. Alloys Compd."},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.powtec.2017.12.058","article-title":"A review of powder additive manufacturing processes for metallic biomaterials","volume":"327","author":"Harun","year":"2018","journal-title":"Powder Technol."},{"key":"ref_103","first-page":"101082","article-title":"Measuring the spreadability of pre-treated and moisturized powders for laser powder bed fusion","volume":"32","author":"Cordova","year":"2020","journal-title":"Addit. Manuf."},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/j.jmst.2015.08.007","article-title":"Effect of Powder Particle Shape on the Properties of In Situ Ti-TiB Composite Materials Produced by Selective Laser Melting","volume":"31","author":"Attar","year":"2015","journal-title":"J. Mater. Sci. Technol."},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.actamat.2010.09.054","article-title":"Influence of powder morphology on thermoelectric anisotropy of spark-plasma-sintered Bi-Te-based thermoelectric materials","volume":"59","author":"Kim","year":"2011","journal-title":"Acta Mater."},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.powtec.2017.07.048","article-title":"Spark plasma sintering and complex shapes: The deformed interfaces approach","volume":"320","author":"Nigito","year":"2017","journal-title":"Powder Technol."},{"key":"ref_107","doi-asserted-by":"crossref","unstructured":"Mani\u00e8re, C., Torresani, E., and Olevsky, E.A. (2019). Simultaneous Spark Plasma Sintering of Multiple Complex Shapes. Materials, 12.","DOI":"10.3390\/ma12040557"},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.matpr.2020.10.1007","article-title":"Synthesis and characterization of wollastonite (CaSio3)\/titanium oxide (TiO2) and hydroxyapatite (HA) ceramic composites for bio-medical applications fabricated by spark plasma sintering technology","volume":"45","author":"Mansoor","year":"2021","journal-title":"Mater. Today Proc."},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1016\/j.scriptamat.2012.02.013","article-title":"Rapid sintering of crack-free zirconia ceramics by pressure-less spark plasma sintering","volume":"66","author":"Salamon","year":"2012","journal-title":"Scr. Mater."},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"2413","DOI":"10.1007\/s00170-021-06810-3","article-title":"Scanning strategy in selective laser melting (SLM): A review","volume":"113","author":"Jia","year":"2021","journal-title":"Int. J. Adv. Manuf. Technol."},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.proeng.2017.01.179","article-title":"The Effect of Layer Thickness at Selective Laser Melting","volume":"174","author":"Sufiiarov","year":"2017","journal-title":"Procedia Eng."},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"8064","DOI":"10.1016\/j.apsusc.2007.02.088","article-title":"Parametric analysis of the selective laser melting process","volume":"253","author":"Yadroitsev","year":"2007","journal-title":"Appl. Surf. Sci."},{"key":"ref_113","first-page":"e4297","article-title":"Plaque Assay for Murine Norovirus","volume":"66","author":"Cunha","year":"2012","journal-title":"J. Vis. Exp."},{"key":"ref_114","doi-asserted-by":"crossref","unstructured":"Brugger, S.D., Baumberger, C., Jost, M., Jenni, W., Brugger, U., and M\u00fchlemann, K. (2012). Automated Counting of Bacterial Colony Forming Units on Agar Plates. PLoS ONE, 7.","DOI":"10.1371\/journal.pone.0033695"},{"key":"ref_115","doi-asserted-by":"crossref","unstructured":"Rahmani, R., Rosenberg, M., Ivask, A., and Kollo, L. (2019). Comparison of mechanical and antibacterial properties of TiO2\/Ag ceramics and Ti6Al4V-TiO2\/Ag composite materials using combined SLM-SPS techniques. Metals, 9.","DOI":"10.3390\/met9080874"},{"key":"ref_116","doi-asserted-by":"crossref","unstructured":"Molan, K., Rahmani, R., Krklec, D., Brojan, M., and Stopar, D. (2022). Phi 6 Bacteriophage Inactivation by Metal Salts, Metal Powders, and Metal Surfaces. Viruses, 14.","DOI":"10.3390\/v14020204"},{"key":"ref_117","doi-asserted-by":"crossref","first-page":"138330","DOI":"10.1016\/j.msea.2019.138330","article-title":"Topology optimization and characterization of Ti6Al4V ELI cellular lattice structures by laser powder bed fusion for biomedical applications","volume":"766","author":"Vilardell","year":"2019","journal-title":"Mater. Sci. Eng. A"},{"key":"ref_118","doi-asserted-by":"crossref","unstructured":"Xiong, Y.-Z., Gao, R.-N., Zhang, H., Dong, L.-L., Li, J.-T., and Li, X. (2020). Rationally designed functionally graded porous Ti6Al4V scaffolds with high strength and toughness built via selective laser melting for load-bearing orthopedic applications. J. Mech. Behav. Biomed. Mater., 104.","DOI":"10.1016\/j.jmbbm.2020.103673"},{"key":"ref_119","doi-asserted-by":"crossref","first-page":"105480","DOI":"10.1016\/j.ijmecsci.2020.105480","article-title":"Sheet and network based functionally graded lattice structures manufactured by selective laser melting: Design, mechanical properties, and simulation","volume":"175","author":"Zhou","year":"2020","journal-title":"Int. J. Mech. Sci."},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"2025","DOI":"10.1557\/jmr.2020.84","article-title":"Influence of selective laser melting scanning speed parameter on the surface morphology, surface roughness, and micropores for manufactured Ti6Al4V parts","volume":"35","author":"Sadali","year":"2020","journal-title":"J. Mater. Res."},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"107643","DOI":"10.1016\/j.matdes.2019.107643","article-title":"Pore functionally graded Ti6Al4V scaffolds for bone tissue engineering application","volume":"168","author":"Wang","year":"2019","journal-title":"Mater. Des."},{"key":"ref_122","doi-asserted-by":"crossref","first-page":"105192","DOI":"10.1016\/j.ijrmhm.2020.105192","article-title":"Perspectives of metal-diamond composites additive manufacturing using SLM-SPS and other techniques for increased wear-impact resistance","volume":"88","author":"Rahmani","year":"2020","journal-title":"Int. J. Refract. Met. Hard Mater."},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.matdes.2017.06.006","article-title":"Compressive properties of functionally graded lattice structures manufactured by selective laser melting","volume":"131","author":"Choy","year":"2017","journal-title":"Mater. Des."},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"13842","DOI":"10.1016\/j.jmrt.2020.09.108","article-title":"Lightweight 3D printed Ti6Al4V-AlSi10Mg hybrid composite for impact resistance and armor piercing shielding","volume":"9","author":"Rahmani","year":"2020","journal-title":"J. Mater. Res. Technol."},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"105735","DOI":"10.1016\/j.ijmecsci.2020.105735","article-title":"Mechanical properties and energy absorption capabilities of functionally graded lattice structures: Experiments and simulations","volume":"182","author":"Bai","year":"2020","journal-title":"Int. J. Mech. Sci."},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"246","DOI":"10.4028\/www.scientific.net\/KEM.799.246","article-title":"Use of Selective Laser Melting for Manufacturing the Porous Stack of a Thermoacoustic Engine","volume":"799","author":"Auriemma","year":"2019","journal-title":"Key Eng. Mater."},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"5415897","DOI":"10.1155\/2019\/5415897","article-title":"Wear Resistance of (Diamond-Ni)-Ti6Al4V Gradient Materials Prepared by Combined Selective Laser Melting and Spark Plasma Sintering Techniques","volume":"2019","author":"Rahmani","year":"2019","journal-title":"Adv. Tribol."},{"key":"ref_128","doi-asserted-by":"crossref","first-page":"4210762","DOI":"10.1155\/2019\/4210762","article-title":"Selective Laser Melting of Diamond-Containing or Postnitrided Materials Intended for Impact-Abrasive Conditions: Experimental and Analytical Study","volume":"2019","author":"Rahmani","year":"2019","journal-title":"Adv. Mater. Sci. Eng."},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.jmbbm.2016.04.041","article-title":"Compensation strategy to reduce geometry and mechanics mismatches in porous biomaterials built with Selective Laser Melting","volume":"70","author":"Bagheri","year":"2017","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"185","DOI":"10.3176\/proc.2019.2.10","article-title":"Bioceramic scaffolds by additive manufacturing for controlled delivery of the antibiotic vancomycin","volume":"68","author":"Kamboj","year":"2019","journal-title":"Proc. Est. Acad. Sci."},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.actbio.2016.10.005","article-title":"Improving the fatigue performance of porous metallic biomaterials produced by Selective Laser Melting","volume":"47","author":"Apers","year":"2017","journal-title":"Acta Biomater."},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.actbio.2020.05.038","article-title":"Tailored mechanical response and mass transport characteristic of selective laser melted porous metallic biomaterials for bone scaffolds","volume":"112","author":"Zhang","year":"2020","journal-title":"Acta Biomater."},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.4028\/www.scientific.net\/AMR.535-537.1222","article-title":"Manufacturing of Porous Biomaterials for Dental Implant Applications through Selective Laser Melting","volume":"535\u2013537","author":"Cardaropoli","year":"2012","journal-title":"Adv. Mater. Res."},{"key":"ref_134","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.colsurfb.2016.10.037","article-title":"In vitro and in vivo evaluation of MgF2 coated AZ31 magnesium alloy porous scaffolds for bone regeneration","volume":"149","author":"Yu","year":"2017","journal-title":"Colloids Surf. B Biointerfaces"},{"key":"ref_135","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.ymeth.2007.01.006","article-title":"Microtitre plate-based antibacterial assay incorporating resazurin as an indicator of cell growth, and its application in the in vitro antibacterial screening of phytochemicals","volume":"42","author":"Sarker","year":"2007","journal-title":"Methods"},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1021\/acsptsci.0c00174","article-title":"Antibacterial and Antiviral Functional Materials: Chemistry and Biological Activity toward Tackling COVID-19-like Pandemics","volume":"4","author":"Balasubramaniam","year":"2021","journal-title":"ACS Pharmacol. Transl. Sci."},{"key":"ref_137","doi-asserted-by":"crossref","first-page":"4310","DOI":"10.1016\/j.apsusc.2010.02.022","article-title":"The comparison of photocatalytic activity of synthesized TiO2 and ZrO2 nanosize onto wool fibers","volume":"256","author":"Moafi","year":"2010","journal-title":"Appl. Surf. Sci."},{"key":"ref_138","first-page":"103013","article-title":"Effect of powder bed preheating on the crack formation and microstructure in ceramic matrix composites fabricated by laser powder-bed fusion process","volume":"58","author":"Maurya","year":"2022","journal-title":"Addit. Manuf."},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"5479","DOI":"10.1016\/j.ceramint.2022.10.071","article-title":"Effect of the B4C content on microstructure, microhardness, corrosion, and neutron shielding properties of Al\u2013B4C composites","volume":"49","author":"Gaylan","year":"2023","journal-title":"Ceram. Int."},{"key":"ref_140","first-page":"77","article-title":"Selective laser melting of aluminium and aluminium metal matrix composites: Review","volume":"31","author":"Sercombe","year":"2016","journal-title":"Mater. Technol."},{"key":"ref_141","doi-asserted-by":"crossref","unstructured":"Rahmani, R., Antonov, M., Kollo, L., Holovenko, Y., and Prashanth, K.G. (2019). Mechanical Behavior of Ti6Al4V Scaffolds Filled with CaSiO3 for Implant Applications. Appl. Sci., 9.","DOI":"10.3390\/app9183844"},{"key":"ref_142","doi-asserted-by":"crossref","first-page":"2037","DOI":"10.1007\/s00170-020-06323-5","article-title":"Design, optimization, and selective laser melting of vin tiles cellular structure-based hip implant","volume":"112","author":"Abate","year":"2021","journal-title":"Int. J. Adv. Manuf. Technol."},{"key":"ref_143","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.matdes.2014.03.068","article-title":"An investigation into the flexural characteristics of functionally graded cobalt chrome femoral stems manufactured using selective laser melting","volume":"60","author":"Hazlehurst","year":"2014","journal-title":"Mater. Des."},{"key":"ref_144","doi-asserted-by":"crossref","unstructured":"Zhang, W., Zhao, W., Li, Q., Zhao, D., Qu, J., Yuan, Z., Cheng, Z., Zhu, X., Zhuang, X., and Zhang, Z. (2021). 3D-printing magnesium\u2013polycaprolactone loaded with melatonin inhibits the development of osteosarcoma by regulating cell-in-cell structures. J. Nanobiotechnol., 19.","DOI":"10.1186\/s12951-021-01012-1"},{"key":"ref_145","doi-asserted-by":"crossref","first-page":"34029","DOI":"10.1038\/srep34029","article-title":"Systematical Evaluation of Mechanically Strong 3D Printed Diluted magnesium Doping Wollastonite Scaffolds on Osteogenic Capacity in Rabbit Calvarial Defects","volume":"6","author":"Sun","year":"2016","journal-title":"Sci. Rep."},{"key":"ref_146","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1016\/j.jma.2022.03.001","article-title":"Recent progress and perspectives in additive manufacturing of magnesium alloys","volume":"10","author":"Zeng","year":"2022","journal-title":"J. Magnes. Alloys"},{"key":"ref_147","doi-asserted-by":"crossref","unstructured":"Izri, Z., Bijanzad, A., Torabnia, S., and Lazoglu, I. (2022). In silico evaluation of lattice designs for additively manufactured total hip implants. Comput. Biol. Med., 144.","DOI":"10.1016\/j.compbiomed.2022.105353"},{"key":"ref_148","doi-asserted-by":"crossref","first-page":"100122","DOI":"10.1016\/j.oceram.2021.100122","article-title":"Ionic substituted hydroxyapatite for bone regeneration applications: A review","volume":"6","author":"Ressler","year":"2021","journal-title":"Open Ceram."},{"key":"ref_149","doi-asserted-by":"crossref","first-page":"111223","DOI":"10.1016\/j.msec.2020.111223","article-title":"Selective laser sintered bio-inspired silicon-wollastonite scaffolds for bone tissue engineering","volume":"116","author":"Kamboj","year":"2020","journal-title":"Mater. Sci. Eng. C"},{"key":"ref_150","doi-asserted-by":"crossref","first-page":"106509","DOI":"10.1088\/2053-1591\/abbd08","article-title":"Explore the feasibility of fabricating pure copper parts with low-laser energy by selective laser melting","volume":"7","author":"Lingqin","year":"2020","journal-title":"Mater. Res. Express"},{"key":"ref_151","first-page":"47","article-title":"Influence of selective laser melting process parameters on texture evolution in pure copper","volume":"270","author":"Jadhav","year":"2019","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_152","doi-asserted-by":"crossref","first-page":"2473","DOI":"10.1007\/s00170-019-04015-3","article-title":"Limits and solutions in processing pure Cu via selective laser melting using a high-power single-mode fiber laser","volume":"104","author":"Colopi","year":"2019","journal-title":"Int. J. Adv. Manuf. Technol."},{"key":"ref_153","doi-asserted-by":"crossref","first-page":"109916","DOI":"10.1016\/j.diamond.2023.109916","article-title":"Fabrication of Localized Diamond-Filled Copper Structures via Selective Laser Melting and Spark Plasma Sintering","volume":"136","author":"Rahmani","year":"2023","journal-title":"Diam. Relat. Mater."},{"key":"ref_154","first-page":"101990","article-title":"Laser-based powder bed fusion additive manufacturing of pure copper","volume":"42","author":"Jadhav","year":"2021","journal-title":"Addit. Manuf."},{"key":"ref_155","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1007\/s00501-021-01107-0","article-title":"Effect of Particle Size Distribution on Laser Powder Bed Fusion Manufacturability of Copper","volume":"166","author":"Bonesso","year":"2021","journal-title":"Berg. Huettenmaenn Monatsh."},{"key":"ref_156","doi-asserted-by":"crossref","first-page":"108406","DOI":"10.1016\/j.matdes.2019.108406","article-title":"Lattice structures of Cu-Cr-Zr copper alloy by selective laser melting: Microstructures, mechanical properties and energy absorption","volume":"187","author":"Ma","year":"2020","journal-title":"Mater. Des."},{"key":"ref_157","doi-asserted-by":"crossref","first-page":"112023","DOI":"10.1016\/j.matdes.2023.112023","article-title":"Green laser powder bed fusion based fabrication and rate-dependent mechanical properties of copper lattices","volume":"231","author":"Kang","year":"2023","journal-title":"Mater. Des."},{"key":"ref_158","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1007\/s00170-022-08878-x","article-title":"High virucidal potential of novel ceramic\u2013metal composites fabricated via hybrid selective laser melting and spark plasma sintering routes","volume":"120","author":"Rahmani","year":"2022","journal-title":"Int. J. Adv. Manuf. Technol."},{"key":"ref_159","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.envpol.2018.02.074","article-title":"Photocatalytic disinfection performance in virus and virus\/bacteria system by Cu-TiO2 nanofibers under visible light","volume":"237","author":"Zheng","year":"2018","journal-title":"Environ. Pollut."},{"key":"ref_160","doi-asserted-by":"crossref","first-page":"104539","DOI":"10.1016\/j.jece.2020.104539","article-title":"Performance of Ag-Cu\/TiO2 photocatalyst prepared by sol-gel method on the inactivation of Escherichia coli and Salmonella typhimurium","volume":"8","year":"2020","journal-title":"J. Environ. Chem. Eng."},{"key":"ref_161","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1007\/s12008-023-01217-8","article-title":"Industry 5.0 or industry 4.0S? Introduction to industry 4.0 and a peek into the prospective industry 5.0 technologies","volume":"17","author":"Santhi","year":"2023","journal-title":"Int. J. Interact. Des. Manuf."},{"key":"ref_162","doi-asserted-by":"crossref","unstructured":"Fraga-Lamas, P., Lopes, S.I., and Fern\u00e1ndez-Caram\u00e9s, T.M. (2021). Green IoT and Edge AI as Key Technological Enablers for a Sustainable Digital Transition towards a Smart Circular Economy: An Industry 5.0 Use Case. Sensors, 21.","DOI":"10.3390\/s21175745"},{"key":"ref_163","doi-asserted-by":"crossref","unstructured":"Rahmani, R., Karimi, J., Resende, P.R., Abrantes, J.C.C., and Lopes, S.I. (2023). Overview of Selective Laser Melting for Industry 5.0: Toward Customizable, Sustainable, and Human-Centric Technologies. Machines, 11.","DOI":"10.3390\/machines11050522"},{"key":"ref_164","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.jor.2022.06.001","article-title":"Industry 5.0 technology capabilities in Trauma and Orthopaedics","volume":"32","author":"Iyengar","year":"2022","journal-title":"J. Orthop."},{"key":"ref_165","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1108\/RPJ-07-2019-0194","article-title":"Customized design and additive manufacturing of kids\u2019 ankle foot orthosis","volume":"26","author":"Banga","year":"2020","journal-title":"Rapid Prototyp. J."},{"key":"ref_166","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1007\/s42452-019-1190-0","article-title":"Axial and torsional buckling analysis of single- and multi-walled carbon nanotubes: Finite element comparison between armchair and zigzag types","volume":"1","author":"Rahmani","year":"2019","journal-title":"SN Appl. Sci."},{"key":"ref_167","unstructured":"Srivathsan, S., Ravichander, B.B., Moghaddam, N.S., Swails, N., and Amerinatanzi, A. (May, January 27). Investigation of the strength of different porous lattice structures manufactured using selective laser melting. Proceedings of the SPIE 11377, Behavior and Mechanics of Multifunctional Materials IX, Online."},{"key":"ref_168","doi-asserted-by":"crossref","first-page":"3411","DOI":"10.1007\/s00170-019-04422-6","article-title":"The manufacturability and compression properties of the Schwarz Diamond type Ti6Al4V cellular lattice fabricated by selective laser melting","volume":"105","author":"Maszybrocka","year":"2019","journal-title":"Int. J. Adv. Manuf. Technol."},{"key":"ref_169","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1007\/s11340-015-0117-y","article-title":"Characterization of Titanium Lattice Structures Fabricated by Selective Laser Melting Using an Adapted Compressive Test Method","volume":"56","author":"Sing","year":"2016","journal-title":"Exp. Mech."},{"key":"ref_170","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/j.actbio.2019.05.046","article-title":"Fatigue behavior of As-built selective laser melted titanium scaffolds with sheet-based gyroid microarchitecture for bone tissue engineering","volume":"94","author":"Kelly","year":"2019","journal-title":"Acta Biomater."},{"key":"ref_171","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1016\/j.msec.2019.03.101","article-title":"Development of a solvent-free polylactide\/calcium carbonate composite for selective laser sintering of bone tissue engineering scaffolds","volume":"101","author":"Gayer","year":"2019","journal-title":"Mater. Sci. Eng. C"},{"key":"ref_172","doi-asserted-by":"crossref","first-page":"3138","DOI":"10.1016\/j.actbio.2012.04.022","article-title":"Micromechanical finite-element modeling and experimental characterization of the compressive mechanical properties of polycaprolactone\u2013hydroxyapatite composite scaffolds prepared by selective laser sintering for bone tissue engineering","volume":"8","author":"Eshraghi","year":"2012","journal-title":"Acta Biomater."},{"key":"ref_173","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.msea.2015.01.031","article-title":"Influence of processing conditions on strut structure and compressive properties of cellular lattice structures fabricated by selective laser melting","volume":"628","author":"Qiu","year":"2015","journal-title":"Mater. Sci. Eng. A"},{"key":"ref_174","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/j.jmbbm.2018.08.048","article-title":"Effect of pore geometry on the fatigue properties and cell affinity of porous titanium scaffolds fabricated by selective laser melting","volume":"88","author":"Zhao","year":"2018","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"ref_175","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.msea.2016.05.075","article-title":"Fracture toughness and tensile strength of 316L stainless steel cellular lattice structures manufactured using the selective laser melting technique","volume":"669","author":"Alsalla","year":"2016","journal-title":"Mater. Sci. Eng. A"},{"key":"ref_176","doi-asserted-by":"crossref","first-page":"106042","DOI":"10.1016\/j.ijmecsci.2020.106042","article-title":"Effects of heat treatment on microstructure and mechanical properties of selective laser melted Ti-6Al-4V lattice materials","volume":"190","author":"Jin","year":"2021","journal-title":"Int. J. Mech. Sci."},{"key":"ref_177","doi-asserted-by":"crossref","first-page":"3311","DOI":"10.1007\/s11661-020-05796-z","article-title":"Challenges and Opportunities in the Selective Laser Melting of Biodegradable Metals for Load-Bearing Bone Scaffold Applications","volume":"51","author":"Carluccio","year":"2020","journal-title":"Metall. Mater. Trans. A"},{"key":"ref_178","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1007\/s00170-018-1913-1","article-title":"Statistical and optimize of lattice structures with selective laser melting (SLM) of Ti6AL4V material","volume":"97","author":"Kadirgama","year":"2018","journal-title":"Int. J. Adv. Manuf. Technol."},{"key":"ref_179","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/s40684-018-0006-9","article-title":"Influence of energy density on energy demand and porosity of 316L stainless steel fabricated by selective laser melting","volume":"5","author":"Peng","year":"2018","journal-title":"Int. J. Precis. Eng. Manuf. Green Technol."},{"key":"ref_180","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/j.jallcom.2018.05.325","article-title":"Synthesis of Ti-5Al, Ti-6Al-7Nb, and Ti-22Al-25Nb alloys from elemental powders using powder-bed fusion additive manufacturing","volume":"763","author":"Polozov","year":"2018","journal-title":"J. Alloys Compd."},{"key":"ref_181","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1002\/jbm.a.33058","article-title":"Manufacturing of individual biodegradable bone substitute implants using selective laser melting technique","volume":"97","author":"Lindner","year":"2011","journal-title":"J. Biomed. Mater. Res. Part A"},{"key":"ref_182","first-page":"20","article-title":"Selective laser melting of pure Zn with high density for biodegradable implant manufacturing","volume":"15","author":"Demir","year":"2017","journal-title":"Addit. Manuf."},{"key":"ref_183","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1002\/jor.22293","article-title":"Selective laser melting-produced porous titanium scaffolds regenerate bone in critical size cortical bone defects","volume":"31","author":"Waarsing","year":"2013","journal-title":"J. Orthop. Res."},{"key":"ref_184","first-page":"85","article-title":"Morphology and surface topography of Ti6Al4V lattice structure fabricated by selective laser sintering","volume":"65","author":"Maszybrocka","year":"2017","journal-title":"Bull. Pol. Acad. Sci. Tech. Sci."},{"key":"ref_185","first-page":"68","article-title":"Crack propagation and fracture toughness of Ti6Al4V alloy produced by selective laser melting","volume":"5","author":"Cain","year":"2015","journal-title":"Addit. Manuf."},{"key":"ref_186","doi-asserted-by":"crossref","first-page":"110945","DOI":"10.1016\/j.matchar.2021.110945","article-title":"Effects of processing parameters and heat treatment on thermal conductivity of additively manufactured AlSi10Mg by selective laser melting","volume":"173","author":"Butler","year":"2021","journal-title":"Mater. Charact."},{"key":"ref_187","doi-asserted-by":"crossref","unstructured":"Harada, Y., Ishida, Y., Miura, D., Watanabe, S., Aoki, H., Miyasaka, T., and Shinya, A. (2020). Mechanical Properties of Selective Laser Sintering Pure Titanium and Ti-6Al-4V, and Its Anisotropy. Materials, 13.","DOI":"10.3390\/ma13225081"},{"key":"ref_188","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.rcim.2017.06.006","article-title":"Selective laser melting of lattice structures: A statistical approach to manufacturability and mechanical behavior","volume":"49","author":"Sing","year":"2018","journal-title":"Robot. Comput. Manuf."},{"key":"ref_189","first-page":"77","article-title":"Effects of build orientation and heat treatment on the microstructure and mechanical properties of selective laser melted Ti6Al4V lattice structures","volume":"5","author":"Wauthle","year":"2015","journal-title":"Addit. Manuf."},{"key":"ref_190","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.msea.2016.06.013","article-title":"A mechanical property evaluation of graded density Al-Si10-Mg lattice structures manufactured by selective laser melting","volume":"670","author":"Maskery","year":"2016","journal-title":"Mater. Sci. Eng. 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