{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T13:29:42Z","timestamp":1764077382003,"version":"build-2065373602"},"reference-count":40,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2022,7,28]],"date-time":"2022-07-28T00:00:00Z","timestamp":1658966400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e Tecnologia","doi-asserted-by":"publisher","award":["UID\/4950\/2020","DSAIPA\/DS\/0041\/2020","PCIF\/SSO\/0082\/2018","PTDC\/PSI-GER\/30852\/2017","PTDC\/PSI-GER\/1326\/2020","FIS-FIS-2015-01 DIA-DiaMarkData"],"award-info":[{"award-number":["UID\/4950\/2020","DSAIPA\/DS\/0041\/2020","PCIF\/SSO\/0082\/2018","PTDC\/PSI-GER\/30852\/2017","PTDC\/PSI-GER\/1326\/2020","FIS-FIS-2015-01 DIA-DiaMarkData"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"name":"INFARMED Research Fund for Health","award":["UID\/4950\/2020","DSAIPA\/DS\/0041\/2020","PCIF\/SSO\/0082\/2018","PTDC\/PSI-GER\/30852\/2017","PTDC\/PSI-GER\/1326\/2020","FIS-FIS-2015-01 DIA-DiaMarkData"],"award-info":[{"award-number":["UID\/4950\/2020","DSAIPA\/DS\/0041\/2020","PCIF\/SSO\/0082\/2018","PTDC\/PSI-GER\/30852\/2017","PTDC\/PSI-GER\/1326\/2020","FIS-FIS-2015-01 DIA-DiaMarkData"]}]},{"name":"the European Foundation for the Study of Diabetes (EFSD)","award":["UID\/4950\/2020","DSAIPA\/DS\/0041\/2020","PCIF\/SSO\/0082\/2018","PTDC\/PSI-GER\/30852\/2017","PTDC\/PSI-GER\/1326\/2020","FIS-FIS-2015-01 DIA-DiaMarkData"],"award-info":[{"award-number":["UID\/4950\/2020","DSAIPA\/DS\/0041\/2020","PCIF\/SSO\/0082\/2018","PTDC\/PSI-GER\/30852\/2017","PTDC\/PSI-GER\/1326\/2020","FIS-FIS-2015-01 DIA-DiaMarkData"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPM"],"abstract":"<jats:p>Theoretical accounts on social decision-making under uncertainty postulate that individual risk preferences are context dependent. Generalization of models of decision-making to dyadic interactions in the personal health context remain to be experimentally addressed. In economic utility-based models, interactive behavioral games provide a framework to investigate probabilistic learning of sequential reinforcement. Here, we model an economic trust game in the context of a chronic disease (Diabetes Type 1) which involves iterated daily decisions in complex social contexts. Ninety-one patients performed experimental trust games in both economic and health settings and were characterized by a multiple self-report set of questionnaires. We found that although our groups can correctly infer pay-off contingencies, they behave differently because patients with a biological profile of preserved glycemic control show adaptive choice behavior both in economic and health domains. On the other hand, patients with a biological profile of loss of glycemic control presented a contrasting behavior, showing non-adaptive choices on both contexts. These results provide a direct translation from neuroeconomics to decision-making in the health domain and biological risk profiles, in a behavioral setting that requires difficult and self-consequential decisions with health impact. Our findings also provide a contextual generalization of mechanisms underlying individual decision-making under uncertainty.<\/jats:p>","DOI":"10.3390\/jpm12081236","type":"journal-article","created":{"date-parts":[[2022,7,28]],"date-time":"2022-07-28T22:43:26Z","timestamp":1659048206000},"page":"1236","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Trust-Based Decision-Making in the Health Context Discriminates Biological Risk Profiles in Type 1 Diabetes"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1745-6891","authenticated-orcid":false,"given":"Helena","family":"Jorge","sequence":"first","affiliation":[{"name":"Coimbra Institute for Biomedical Imaging and Translational Research, CIBIT\/ICNAS, Faculty of Medicine, University of Coimbra, 3004-531 Coimbra, Portugal"},{"name":"PIDFIF-Inter-University PhD Program in Clinical Psychology, Family Psychology and Family Intervention, Faculty of Psychology and Educational Sciences of Coimbra, Faculty of Psychology of Lisbon, 1649-013 Lisboa, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5620-2424","authenticated-orcid":false,"given":"Isabel C.","family":"Duarte","sequence":"additional","affiliation":[{"name":"Coimbra Institute for Biomedical Imaging and Translational Research, CIBIT\/ICNAS, Faculty of Medicine, University of Coimbra, 3004-531 Coimbra, Portugal"}]},{"given":"Carla","family":"Baptista","sequence":"additional","affiliation":[{"name":"Endocrinology, Diabetes and Metabolism Department (SEMD), University and Hospital Center of Coimbra, 3004-561 Coimbra, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9011-2230","authenticated-orcid":false,"given":"Ana Paula","family":"Relvas","sequence":"additional","affiliation":[{"name":"Faculty of Psychology and Educational Sciences & Center for Social Studies, University of Coimbra, 3004-531 Coimbra, Portugal"}]},{"given":"Miguel","family":"Castelo-Branco","sequence":"additional","affiliation":[{"name":"Coimbra Institute for Biomedical Imaging and Translational Research, CIBIT\/ICNAS, Faculty of Medicine, University of Coimbra, 3004-531 Coimbra, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2022,7,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jebo.2011.08.009","article-title":"Experimental Methods: Between-Subject and Within-Subject Design","volume":"81","author":"Charness","year":"2012","journal-title":"J. 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