{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T02:00:44Z","timestamp":1773712844439,"version":"3.50.1"},"reference-count":30,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2024,4,22]],"date-time":"2024-04-22T00:00:00Z","timestamp":1713744000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPM"],"abstract":"<jats:p>Background: Coronary artery calcification is a predictor of adverse outcomes after percutaneous coronary intervention (PCI). Intravascular lithotripsy (IVL) is a promising tool for the treatment of calcified lesions. The aim of this study was to assess the effectiveness and safety of IVL. Methods: A single-center observational study of PCI procedure, with assessment of the outcomes of patients undergoing PCI using IVL, was performed. Angiographic procedural success was used as the primary effectiveness endpoint. The primary safety endpoint was defined as a composite of cardiac death, myocardial infarction and target vessel revascularization within 30 days. Results: A total of 111 patients were included. Indications for PCI spanned the spectrum of chronic (53.2%) and acute coronary syndromes (43%). Lesion preparation before IVL was performed with non-compliant (42%), cutting or OPN (14.4%) balloons and with atherectomy techniques in 11% of procedures. Intravascular imaging was used in 21.6% of procedures. The primary effectiveness endpoint was achieved in 100% and the primary safety endpoint in 3.6% of procedures. Peri-procedural complications were minimal and successfully resolved. Conclusions: IVL was an effective and safe technique for the treatment of calcified coronary lesions. These findings contribute to the growing body of evidence supporting the use of IVL in the management of these challenging scenarios.<\/jats:p>","DOI":"10.3390\/jpm14040438","type":"journal-article","created":{"date-parts":[[2024,4,22]],"date-time":"2024-04-22T07:44:09Z","timestamp":1713771849000},"page":"438","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Coronary Intravascular Lithotripsy Effectiveness and Safety in a Real-World Cohort"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4857-0910","authenticated-orcid":false,"given":"Catarina","family":"Oliveira","sequence":"first","affiliation":[{"name":"Servi\u00e7o de Cardiologia, Departamento de Cora\u00e7\u00e3o e Vasos, CHULN Hospital de Santa Maria, Av Prof. Egas Moniz, 1649-028 Lisboa, Portugal"}]},{"given":"Marta","family":"Vilela","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Cardiologia, Departamento de Cora\u00e7\u00e3o e Vasos, CHULN Hospital de Santa Maria, Av Prof. Egas Moniz, 1649-028 Lisboa, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8363-0363","authenticated-orcid":false,"given":"Miguel","family":"Nobre Menezes","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Cardiologia, Departamento de Cora\u00e7\u00e3o e Vasos, CHULN Hospital de Santa Maria, Av Prof. Egas Moniz, 1649-028 Lisboa, Portugal"},{"name":"Structural and Coronary Heart Disease Unit, Centro Cardiovascular da Universidade de Lisboa (CCUL@RISE), Faculdade de Medicina, Universidade de Lisboa, Av Prof. Egas Moniz, 1649-028 Lisboa, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8988-5412","authenticated-orcid":false,"given":"Jo\u00e3o","family":"Silva Marques","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Cardiologia, Departamento de Cora\u00e7\u00e3o e Vasos, CHULN Hospital de Santa Maria, Av Prof. Egas Moniz, 1649-028 Lisboa, Portugal"},{"name":"Structural and Coronary Heart Disease Unit, Centro Cardiovascular da Universidade de Lisboa (CCUL@RISE), Faculdade de Medicina, Universidade de Lisboa, Av Prof. Egas Moniz, 1649-028 Lisboa, Portugal"}]},{"given":"Cl\u00e1udia Moreira","family":"Jorge","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Cardiologia, Departamento de Cora\u00e7\u00e3o e Vasos, CHULN Hospital de Santa Maria, Av Prof. Egas Moniz, 1649-028 Lisboa, Portugal"},{"name":"Structural and Coronary Heart Disease Unit, Centro Cardiovascular da Universidade de Lisboa (CCUL@RISE), Faculdade de Medicina, Universidade de Lisboa, Av Prof. Egas Moniz, 1649-028 Lisboa, Portugal"}]},{"given":"Tiago","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Cardiologia, Departamento de Cora\u00e7\u00e3o e Vasos, CHULN Hospital de Santa Maria, Av Prof. Egas Moniz, 1649-028 Lisboa, Portugal"},{"name":"Structural and Coronary Heart Disease Unit, Centro Cardiovascular da Universidade de Lisboa (CCUL@RISE), Faculdade de Medicina, Universidade de Lisboa, Av Prof. Egas Moniz, 1649-028 Lisboa, Portugal"}]},{"given":"Jos\u00e9","family":"Almeida Duarte","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Cardiologia, Departamento de Cora\u00e7\u00e3o e Vasos, CHULN Hospital de Santa Maria, Av Prof. Egas Moniz, 1649-028 Lisboa, Portugal"}]},{"given":"Jos\u00e9","family":"Marques da Costa","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Cardiologia, Departamento de Cora\u00e7\u00e3o e Vasos, CHULN Hospital de Santa Maria, Av Prof. Egas Moniz, 1649-028 Lisboa, Portugal"}]},{"given":"Pedro","family":"Carrilho Ferreira","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Cardiologia, Departamento de Cora\u00e7\u00e3o e Vasos, CHULN Hospital de Santa Maria, Av Prof. Egas Moniz, 1649-028 Lisboa, Portugal"},{"name":"Structural and Coronary Heart Disease Unit, Centro Cardiovascular da Universidade de Lisboa (CCUL@RISE), Faculdade de Medicina, Universidade de Lisboa, Av Prof. Egas Moniz, 1649-028 Lisboa, Portugal"}]},{"given":"Ana Rita","family":"Francisco","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Cardiologia, Departamento de Cora\u00e7\u00e3o e Vasos, CHULN Hospital de Santa Maria, Av Prof. Egas Moniz, 1649-028 Lisboa, Portugal"},{"name":"Structural and Coronary Heart Disease Unit, Centro Cardiovascular da Universidade de Lisboa (CCUL@RISE), Faculdade de Medicina, Universidade de Lisboa, Av Prof. Egas Moniz, 1649-028 Lisboa, Portugal"}]},{"given":"Pedro Pinto","family":"Cardoso","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Cardiologia, Departamento de Cora\u00e7\u00e3o e Vasos, CHULN Hospital de Santa Maria, Av Prof. Egas Moniz, 1649-028 Lisboa, Portugal"},{"name":"Structural and Coronary Heart Disease Unit, Centro Cardiovascular da Universidade de Lisboa (CCUL@RISE), Faculdade de Medicina, Universidade de Lisboa, Av Prof. Egas Moniz, 1649-028 Lisboa, Portugal"}]},{"given":"Fausto J.","family":"Pinto","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Cardiologia, Departamento de Cora\u00e7\u00e3o e Vasos, CHULN Hospital de Santa Maria, Av Prof. Egas Moniz, 1649-028 Lisboa, Portugal"},{"name":"Structural and Coronary Heart Disease Unit, Centro Cardiovascular da Universidade de Lisboa (CCUL@RISE), Faculdade de Medicina, Universidade de Lisboa, Av Prof. Egas Moniz, 1649-028 Lisboa, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2024,4,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1016\/j.jcin.2021.03.036","article-title":"Principles of Intravascular Lithotripsy for Calcific Plaques Modification","volume":"14","author":"Kereiakes","year":"2021","journal-title":"JACC Cardiovasc. 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