{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T13:28:52Z","timestamp":1777382932227,"version":"3.51.4"},"reference-count":170,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2023,2,7]],"date-time":"2023-02-07T00:00:00Z","timestamp":1675728000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Funda\u00e7\u00e3o para a Ci\u00eancia e Tecnologia, I. P (FCT)","award":["UIDB\/04292\/2020"],"award-info":[{"award-number":["UIDB\/04292\/2020"]}]},{"name":"Funda\u00e7\u00e3o para a Ci\u00eancia e Tecnologia, I. P (FCT)","award":["UIDP\/04292\/2020"],"award-info":[{"award-number":["UIDP\/04292\/2020"]}]},{"name":"Funda\u00e7\u00e3o para a Ci\u00eancia e Tecnologia, I. 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P (FCT)","award":["EAPA_451\/2016"],"award-info":[{"award-number":["EAPA_451\/2016"]}]},{"name":"European Regional Development Fund","award":["UIDB\/04292\/2020"],"award-info":[{"award-number":["UIDB\/04292\/2020"]}]},{"name":"European Regional Development Fund","award":["UIDP\/04292\/2020"],"award-info":[{"award-number":["UIDP\/04292\/2020"]}]},{"name":"European Regional Development Fund","award":["LA\/P\/0069\/2020"],"award-info":[{"award-number":["LA\/P\/0069\/2020"]}]},{"name":"European Regional Development Fund","award":["EAPA_451\/2016"],"award-info":[{"award-number":["EAPA_451\/2016"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>Currently, algae arouse a growing interest in the pharmaceutical and cosmetic area due to the fact that they have a great diversity of bioactive compounds with the potential for pharmacological and nutraceutical applications. Due to lifestyle modifications brought on by rapid urbanization, diabetes mellitus, a metabolic illness, is the third largest cause of death globally. The hunt for an efficient natural-based antidiabetic therapy is crucial to battling diabetes and the associated consequences due to the unfavorable side effects of currently available antidiabetic medications. Finding the possible advantages of algae for the control of diabetes is crucial for the creation of natural drugs. Many of algae\u2019s metabolic processes produce bioactive secondary metabolites, which give algae their diverse chemical and biological features. Numerous studies have demonstrated the antioxidant and antidiabetic benefits of algae, mostly by blocking carbohydrate hydrolyzing enzyme activity, such as \u03b1-amylase and \u03b1-glucosidase. Additionally, bioactive components from algae can lessen diabetic symptoms in vivo. Therefore, the current review concentrates on the role of various secondary bioactive substances found naturally in algae and their potential as antioxidants and antidiabetic materials, as well as the urgent need to apply these substances in the pharmaceutical industry.<\/jats:p>","DOI":"10.3390\/life13020460","type":"journal-article","created":{"date-parts":[[2023,2,7]],"date-time":"2023-02-07T03:24:13Z","timestamp":1675740253000},"page":"460","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":68,"title":["Antioxidant and Antidiabetic Activity of Algae"],"prefix":"10.3390","volume":"13","author":[{"given":"Atef Mohamed","family":"Abo-Shady","sequence":"first","affiliation":[{"name":"Botany Department, Faculty of Science, Tanta University, Tanta 31527, Egypt"}]},{"given":"Saly Farouk","family":"Gheda","sequence":"additional","affiliation":[{"name":"Botany Department, Faculty of Science, Tanta University, Tanta 31527, Egypt"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3996-0047","authenticated-orcid":false,"given":"Gehan Ahmed","family":"Ismail","sequence":"additional","affiliation":[{"name":"Botany Department, Faculty of Science, Tanta University, Tanta 31527, Egypt"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5244-221X","authenticated-orcid":false,"given":"Jo\u00e3o","family":"Cotas","sequence":"additional","affiliation":[{"name":"MARE\u2014Marine and Environmental Sciences Centre\/ARNET\u2014Aquatic Research Network, Department of Life Sciences, University of Coimbra, Cal\u00e7ada Martim de Freitas, 3000-456 Coimbra, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6819-0619","authenticated-orcid":false,"given":"Leonel","family":"Pereira","sequence":"additional","affiliation":[{"name":"MARE\u2014Marine and Environmental Sciences Centre\/ARNET\u2014Aquatic Research Network, Department of Life Sciences, University of Coimbra, Cal\u00e7ada Martim de Freitas, 3000-456 Coimbra, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9149-1209","authenticated-orcid":false,"given":"Omnia Hamdy","family":"Abdel-Karim","sequence":"additional","affiliation":[{"name":"Botany Department, Faculty of Science, Tanta University, Tanta 31527, Egypt"},{"name":"Bioprocess Engineering & AlgaePARC, Wageningen University and Research, 6700 AA Wageningen, The Netherlands"}]}],"member":"1968","published-online":{"date-parts":[[2023,2,7]]},"reference":[{"key":"ref_1","unstructured":"International Diabetes Federation (IDF) (2023, January 31). 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