{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T04:46:57Z","timestamp":1760244417582,"version":"build-2065373602"},"reference-count":34,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","award":["UID\/QUI\/00100\/2019","UIDB\/00100\/2020","UIDP\/00100\/2020","LA\/P\/0056\/2020","PD\/BD\/114399\/2016"],"award-info":[{"award-number":["UID\/QUI\/00100\/2019","UIDB\/00100\/2020","UIDP\/00100\/2020","LA\/P\/0056\/2020","PD\/BD\/114399\/2016"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molbank"],"abstract":"<jats:p>The salan zirconium complex of formula [(H2N2O2)ZrCl2] (H2N2O2H2 = HOPh\u2019CH2NH(CH2)2NHCH2Ph\u2019OH, where Ph\u2019 = 2,4-(CMe2Ph)C6H2) was synthesized and fully characterized by NMR and single-crystal X-ray diffraction. The solid-state molecular structure of [(H2N2O2)ZrCl2] shows distorted octahedral geometry around the zirconium center with the salan ligand adopting a \u03b2-\u039b-cis conformation.<\/jats:p>","DOI":"10.3390\/m1511","type":"journal-article","created":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T03:32:25Z","timestamp":1669865545000},"page":"M1511","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["6,6\u2032-((Ethane-1,2-diylbis(azanediyl))bis(methylene))bis(2,4-bis(2-phenylpropan-2-yl)phenolate)zirconium(IV) Dichlorido"],"prefix":"10.3390","volume":"2022","author":[{"given":"Joana","family":"Hip\u00f3lito","sequence":"first","affiliation":[{"name":"Centro de Qu\u00edmica Estrutural, Instituto Superior T\u00e9cnico, Universidade de Lisboa, Av. Rovisco Pais 1, 1049-001 Lisboa, Portugal"}]},{"given":"Ana M.","family":"Martins","sequence":"additional","affiliation":[{"name":"Centro de Qu\u00edmica Estrutural, Instituto Superior T\u00e9cnico, Universidade de Lisboa, Av. Rovisco Pais 1, 1049-001 Lisboa, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7938-9850","authenticated-orcid":false,"given":"Luis G.","family":"Alves","sequence":"additional","affiliation":[{"name":"Centro de Qu\u00edmica Estrutural, Institute of Molecular Sciences, Associa\u00e7\u00e3o do Instituto Superior T\u00e9cnico para a Investiga\u00e7\u00e3o e Desenvolvimento, Av. Rovisco Pais 1, 1049-003 Lisboa, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.inoche.2017.07.016","article-title":"A chiral multidentate salan-supported heterobimetallic catalyst for asymmetric Friedel-Crafts reaction","volume":"84","author":"Xiong","year":"2017","journal-title":"Inorg. Chem. Commun."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"121546","DOI":"10.1016\/j.jorganchem.2020.121546","article-title":"Synthesis of chiral salan ligands with bulky substituents and their application in Cu-catalyzed asymmetric Henry reaction","volume":"928","author":"Wang","year":"2020","journal-title":"J. Organomet. Chem."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"2976","DOI":"10.1002\/adsc.202000290","article-title":"Zirconium-Salan Catalyzed Enantioselective \u03b1-Hydroxylation of \u03b2-Keto Esters","volume":"362","author":"Chen","year":"2020","journal-title":"Adv. Synth. Catal."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"15486","DOI":"10.1021\/acs.joc.8b02340","article-title":"Organic Solvent-Free, Pd(II)-Salan Complex-Catalyzed Synthesis of Biaryls via Suzuki-Miyaura Cross-Coupling in Water and Air","volume":"83","author":"Bunda","year":"2018","journal-title":"J. Org. Chem."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"3219","DOI":"10.1016\/j.jorganchem.2009.06.030","article-title":"Enantioselective pinacol coupling reaction of aromatic aldehydes catalyzed by chiral vanadium complexes","volume":"694","author":"Sun","year":"2009","journal-title":"J. Organomet. Chem."},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Hip\u00f3lito, J., Martins, A.M., and Alves, L.G. (2022). Synthesis and Application of New Salan Titanium Complexes in the Catalytic Reduction of Aldehydes. Molecules, 27.","DOI":"10.3390\/molecules27206821"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1021\/ma902626e","article-title":"Same Ligand, Different Metals: Diiodo-Salan Complexes of the Group 4 Triad in Isospecific Polymerization of 1-Hexene and Propylene","volume":"43","author":"Cohen","year":"2010","journal-title":"Macromolecules"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"2111","DOI":"10.1002\/pola.27218","article-title":"Olefin polymerization and copolymerization by complexes bearing [ONNO]-Type salan ligands: Effect of ligand structure and metal type (titanium, zirconium, and vanadium)","volume":"52","author":"Spaleniak","year":"2014","journal-title":"J. Polym. Sci. A Polym. Chem."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"5159","DOI":"10.1021\/om9004274","article-title":"Group 4 Metal Complexes Supported by [ONNO]-Type Bis(o-aminophenolato) Ligands: Synthesis, Structure, and \u03b1-Olefin Polymerization Activity","volume":"28","author":"Meppelder","year":"2009","journal-title":"Organometallics"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"9028","DOI":"10.1021\/acs.inorgchem.8b01046","article-title":"Synthesis and Characterization of Dinuclear Salan Rare-Earth Metal Complexes and Their Application in the Homo- and Copolymerization of Cyclic Esters","volume":"57","author":"Ouyang","year":"2018","journal-title":"Inorg. Chem."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"7250","DOI":"10.1021\/ma061028j","article-title":"Group 4 Complexes with Aminebisphenolate Ligands and Their Application for the Ring Opening Polymerization of Cyclic Esters","volume":"39","author":"Chmura","year":"2006","journal-title":"Macromolecules"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1002\/macp.201300333","article-title":"Aluminum Initiators Supported by Asymmetric [ONNO\u2019]-Type Salan Ligands for the Ring-Opening Polymerization of rac-Lactide","volume":"214","author":"Sumrit","year":"2013","journal-title":"Macromol. Chem. Phys."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1351\/pac200880051071","article-title":"Asymmetric epoxidation of olefins catalyzed by Ti(salan) complexes using aqueous hydrogen peroxide as the oxidant","volume":"80","author":"Matsumoto","year":"2008","journal-title":"Pure Appl. Chem."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1021\/acs.orglett.5b00281","article-title":"Regio- and Enantioselective Catalytic Monoepoxidation of Conjugated Dienes: Synthesis of Chiral Allylic cis-Epoxides","volume":"17","author":"Jat","year":"2015","journal-title":"Org. Lett."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"14329","DOI":"10.1002\/chem.201404157","article-title":"Titanium Salan Catalysts for the Asymmetric Epoxidation of Alkenes: Steric and Electronic Factors Governing the Activity and Enantioselectivity","volume":"20","author":"Talsi","year":"2014","journal-title":"Chem.-Eur. J."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"5568","DOI":"10.1002\/ejic.201000792","article-title":"Titanium(IV)-Salan Catalysts for Asymmetric Sulfoxidation with Hydrogen Peroxide","volume":"2010","author":"Avecilla","year":"2010","journal-title":"Eur. J. Inorg. Chem."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1002\/aoc.2968","article-title":"Titanium-salan-catalyzed asymmetric sulfoxidations with H2O2: Design of more versatile catalysts","volume":"27","author":"Talsi","year":"2013","journal-title":"Appl. Organomet. Chem."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.cattod.2016.03.006","article-title":"Ti-Salan catalyzed asymmetric sulfoxidation of pyridylmethylthiobenzimidazoles to optically pure proton pump inhibitors","volume":"279","author":"Talsi","year":"2017","journal-title":"Cat. Today"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.jorganchem.2018.06.011","article-title":"New salan and salen vanadium complexes: Synthesis and application in sulfoxidation catalysis","volume":"870","author":"Maru","year":"2018","journal-title":"J. Organomet. Chem."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"3170","DOI":"10.1021\/ic500001j","article-title":"C1-Symmetrical Titanium(IV) Complexes of Salan Ligands with Differently Substituted Aromatic Rings: Enhanced Cytotoxic Activity","volume":"53","author":"Glasner","year":"2014","journal-title":"Inorg. Chem."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"2775","DOI":"10.1002\/chem.200902312","article-title":"Cytotoxic Titanium Salan Complexes: Surprising Interaction of Salan and Alkoxy Ligands","volume":"16","author":"Immel","year":"2010","journal-title":"Chem. Eur. J."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1002\/cmdc.201100593","article-title":"Cytotoxic Salan-Titanium(IV) Complexes: High Activity Toward a Range of Sensitive and Drug-Resistant Cell Lines, and Mechanistic Insights","volume":"7","author":"Manna","year":"2012","journal-title":"ChemMedChem"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"5241","DOI":"10.1039\/c2dt11514j","article-title":"Highly Cytotoxic vanadium(V) complexes of salan ligands; insights on the role of hydrolysis","volume":"41","author":"Reytman","year":"2012","journal-title":"Dalton Trans."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"16475","DOI":"10.1039\/C5DT01618E","article-title":"Synthesis and X-ray structure analysis of cytotoxic heptacoordinate sulfonamide salan titanium(IV)-bis-chelates","volume":"44","author":"Zhao","year":"2015","journal-title":"Dalton Trans."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1186\/1752-153X-7-135","article-title":"Monomeric Ti(IV) homopiperazine complexes and their exploitation for the ring opening polymerization of rac-lactide","volume":"7","author":"Hancock","year":"2013","journal-title":"Chem. Cent. J."},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Cohen, A., Yeori, A., Kopilov, J., Goldberg, I., and Kol, M. (2008). Construction of C1-symmetric zirconium complexes by the design of new Salan ligands. Coordination chemistry and preliminary polymerization catalysis studies. Chem. Commun., 2149\u20132151.","DOI":"10.1039\/b719834e"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1021\/om801058w","article-title":"C1-Symmetric Zirconium Complexes of [ONNO\u2019]-Type Salan Ligands: Accurate Control of Catalyst Activity, Isospecificity, and Molecular Weight in 1-Hexene Polymerization","volume":"28","author":"Cohen","year":"2009","journal-title":"Organometallics"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1039\/C4RA13236J","article-title":"Comparative study of ring-opening polymerization of L-lactide and \u03b5-caprolactone using zirconium hexadentate bis(aminophenolate) complexes as catalysts","volume":"5","author":"Ou","year":"2015","journal-title":"RSC Adv."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"13062","DOI":"10.1021\/ja0647654","article-title":"Diastereomerically-Specific Zirconium Complexes of Chiral Salan Ligands: Isospecific Polymerization of 1-Hexene and 4-Methyl-1-pentene and Cyclopolymerization of 1,5-Hexadiene","volume":"128","author":"Yeori","year":"2006","journal-title":"J. Am. Chem. Soc."},{"key":"ref_30","unstructured":"(1997\u20132003). SAINT, Bruker AXS Inc.. Version 7.03A."},{"key":"ref_31","unstructured":"Sheldrick, G.M. (1996). SADABS, Software for Empirical Absorption Corrections, University of G\u00f6ttingen."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1107\/S0021889898007717","article-title":"SIR97: A new tool for crystal structure determination and refinement","volume":"32","author":"Altomare","year":"1999","journal-title":"J. Appl. Cryst."},{"key":"ref_33","first-page":"3","article-title":"Crystal structure and refinement with SHELXL","volume":"C71","author":"Sheldrick","year":"2015","journal-title":"Acta Cryst."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1107\/S0021889899006020","article-title":"WinGX suite for small-molecule single-crystal crystallography","volume":"32","author":"Farrugia","year":"1999","journal-title":"J. Appl. Cryst."}],"container-title":["Molbank"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1422-8599\/2022\/4\/M1511\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:31:06Z","timestamp":1760146266000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1422-8599\/2022\/4\/M1511"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,1]]},"references-count":34,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2022,12]]}},"alternative-id":["M1511"],"URL":"https:\/\/doi.org\/10.3390\/m1511","relation":{},"ISSN":["1422-8599"],"issn-type":[{"type":"electronic","value":"1422-8599"}],"subject":[],"published":{"date-parts":[[2022,12,1]]}}}