{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T19:51:03Z","timestamp":1773172263824,"version":"3.50.1"},"reference-count":57,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2021,4,29]],"date-time":"2021-04-29T00:00:00Z","timestamp":1619654400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["PD\/BD\/140202\/2018"],"award-info":[{"award-number":["PD\/BD\/140202\/2018"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["POCI-01-0145-FEDER-030498-FunImp"],"award-info":[{"award-number":["POCI-01-0145-FEDER-030498-FunImp"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["UID\/EEA\/04436\/2019"],"award-info":[{"award-number":["UID\/EEA\/04436\/2019"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Materials"],"abstract":"<jats:p>(1) It is estimated that 10% of the world\u2019s population will need a dental implant in their lifetime. Despite all the advances in the comprehension of dental implant designs, materials and techniques, traditional implants still have many limitations. Customized root-analogue implants are, therefore, gaining increased interest in dental rehabilitation and are expected to not only preserve more hard and soft tissues but also avoid a second surgery and improve patient overall satisfaction. In this sense, the aim of this review was to collect and analyse the clinical trials and case reports on customized root-analogue implants available in the literature; (2) This review was carried out according to the PRISMA Statement. An electronic database search was performed using five databases: PubMed, Google Scholar, Medline, Science Direct, and Scopus. The following keywords were used for gathering data: custom-made, dental implants, root-analogue, anatomical, customized and tooth-like; (3) 15 articles meeting the inclusion criteria\u2014articles reporting clinical trials, case reports or animal studies and articles with root-analogue implants and articles with totally customized implant geometries\u2014were selected for the qualitative synthesis. The design and manufacturing techniques, implant material and surface treatments were assessed and discussed; (4) The performance of some root-analogue implants with specific features (i.e., macro-retentions) was successful, with no signs of infection, periodontitis nor bleeding during the follow-up periods.<\/jats:p>","DOI":"10.3390\/ma14092296","type":"journal-article","created":{"date-parts":[[2021,4,29]],"date-time":"2021-04-29T01:43:24Z","timestamp":1619660604000},"page":"2296","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Customized Root-Analogue Implants: A Review on Outcomes from Clinical Trials and Case Reports"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7119-432X","authenticated-orcid":false,"given":"Telma","family":"Dantas","sequence":"first","affiliation":[{"name":"CMEMS (Center for Micro Electro Mechanical Systems), University of Minho, 4800-058 Guimar\u00e3es, Portugal"},{"name":"MIT Portugal Program\u2014School of Engineering, University of Minho, 4800-058 Guimar\u00e3es, Portugal"}]},{"given":"Sara","family":"Madeira","sequence":"additional","affiliation":[{"name":"CMEMS (Center for Micro Electro Mechanical Systems), University of Minho, 4800-058 Guimar\u00e3es, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5782-7987","authenticated-orcid":false,"given":"Michael","family":"Gasik","sequence":"additional","affiliation":[{"name":"School of Chemical Engineering, Aalto University Foundation, 02150 Espoo, Finland"}]},{"given":"Paula","family":"Vaz","sequence":"additional","affiliation":[{"name":"Fixed Prosthodontics, Genetics\u2014Faculty of Dental Medicine, University of Porto, 4200-135 Porto, Portugal"}]},{"given":"Filipe","family":"Silva","sequence":"additional","affiliation":[{"name":"CMEMS (Center for Micro Electro Mechanical Systems), University of Minho, 4800-058 Guimar\u00e3es, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2021,4,29]]},"reference":[{"key":"ref_1","first-page":"7","article-title":"Correlation between insertion torque and implant stability quotient in tapered implants with knife-edge thread design","volume":"15","author":"Baldi","year":"2018","journal-title":"Biomed. 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