{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T03:55:00Z","timestamp":1778817300810,"version":"3.51.4"},"reference-count":190,"publisher":"MDPI AG","issue":"17","license":[{"start":{"date-parts":[[2024,8,24]],"date-time":"2024-08-24T00:00:00Z","timestamp":1724457600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Science and Technology (FCT, Portugal) for financial support through national funds FCT\/MCTES (PIDDAC) to CIMO","award":["UIDB\/00690\/2020"],"award-info":[{"award-number":["UIDB\/00690\/2020"]}]},{"name":"Science and Technology (FCT, Portugal) for financial support through national funds FCT\/MCTES (PIDDAC) to CIMO","award":["UIDP\/00690\/2020"],"award-info":[{"award-number":["UIDP\/00690\/2020"]}]},{"name":"Science and Technology (FCT, Portugal) for financial support through national funds FCT\/MCTES (PIDDAC) to CIMO","award":["LA\/P\/0007\/2020"],"award-info":[{"award-number":["LA\/P\/0007\/2020"]}]},{"name":"SusTEC","award":["UIDB\/00690\/2020"],"award-info":[{"award-number":["UIDB\/00690\/2020"]}]},{"name":"SusTEC","award":["UIDP\/00690\/2020"],"award-info":[{"award-number":["UIDP\/00690\/2020"]}]},{"name":"SusTEC","award":["LA\/P\/0007\/2020"],"award-info":[{"award-number":["LA\/P\/0007\/2020"]}]},{"name":"FCT","award":["UIDB\/00690\/2020"],"award-info":[{"award-number":["UIDB\/00690\/2020"]}]},{"name":"FCT","award":["UIDP\/00690\/2020"],"award-info":[{"award-number":["UIDP\/00690\/2020"]}]},{"name":"FCT","award":["LA\/P\/0007\/2020"],"award-info":[{"award-number":["LA\/P\/0007\/2020"]}]},{"name":"CEEC Institutional","award":["UIDB\/00690\/2020"],"award-info":[{"award-number":["UIDB\/00690\/2020"]}]},{"name":"CEEC Institutional","award":["UIDP\/00690\/2020"],"award-info":[{"award-number":["UIDP\/00690\/2020"]}]},{"name":"CEEC Institutional","award":["LA\/P\/0007\/2020"],"award-info":[{"award-number":["LA\/P\/0007\/2020"]}]},{"name":"Wastesilk","award":["UIDB\/00690\/2020"],"award-info":[{"award-number":["UIDB\/00690\/2020"]}]},{"name":"Wastesilk","award":["UIDP\/00690\/2020"],"award-info":[{"award-number":["UIDP\/00690\/2020"]}]},{"name":"Wastesilk","award":["LA\/P\/0007\/2020"],"award-info":[{"award-number":["LA\/P\/0007\/2020"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Materials"],"abstract":"<jats:p>Wound healing, a complex physiological process orchestrating intricate cellular and molecular events, seeks to restore tissue integrity. The burgeoning interest in leveraging the therapeutic potential of natural substances for advanced wound dressings is a recent phenomenon. Notably, Sericin, a silk-derived protein, and Chelidonium majus L. (C.\u00a0majus), a botanical agent, have emerged as compelling candidates, providing a unique combination of natural elements that may revolutionize conventional wound care approaches. Sericin, renowned for its diverse properties, displays unique properties that accelerate the wound healing process. Simultaneously, C. majus, with its diverse pharmacological compounds, shows promise in reducing inflammation and promoting tissue regeneration. As the demand for innovative wound care solutions increases, understanding the therapeutic potential of natural products becomes imperative. This review synthesizes current knowledge on Sericin and C. majus, envisioning their future roles in advancing wound management strategies. The exploration of these natural substances as constituents of wound dressings provides a promising avenue for developing sustainable, effective, and biocompatible materials that could significantly impact the field of wound healing.<\/jats:p>","DOI":"10.3390\/ma17174199","type":"journal-article","created":{"date-parts":[[2024,8,26]],"date-time":"2024-08-26T03:32:01Z","timestamp":1724643121000},"page":"4199","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Enhancing Wound Healing: A Comprehensive Review of Sericin and Chelidonium majus L. as Potential Dressings"],"prefix":"10.3390","volume":"17","author":[{"given":"Ana","family":"Borges","sequence":"first","affiliation":[{"name":"Centro de Investiga\u00e7\u00e3o da Montanha (CIMO), Instituto Polit\u00e9cnico de Bragan\u00e7a, Campus de Santa Apol\u00f3nia, 5300-253 Bragan\u00e7a, Portugal"},{"name":"Grupo de Investigaci\u00f3n en Desarrollo y Evaluaci\u00f3n de Formas Farmac\u00e9uticas y Sistemas de Liberaci\u00f3n Controlada, Facultad de Farmacia, Universidad de Salamanca, Campus Miguel de Unamuno s\/n, 37007 Salamanca, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4810-9673","authenticated-orcid":false,"given":"Mar\u00eda Luisa Mart\u00edn","family":"Calvo","sequence":"additional","affiliation":[{"name":"Grupo de Investigaci\u00f3n en Fisiolog\u00eda y Farmacolog\u00eda, Facultad de Farmacia, Universidad de Salamanca, Campus Miguel de Unamuno s\/n, 37007 Salamanca, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6989-1169","authenticated-orcid":false,"given":"Josiana A.","family":"Vaz","sequence":"additional","affiliation":[{"name":"Centro de Investiga\u00e7\u00e3o da Montanha (CIMO), Instituto Polit\u00e9cnico de Bragan\u00e7a, Campus de Santa Apol\u00f3nia, 5300-253 Bragan\u00e7a, Portugal"},{"name":"Laborat\u00f3rio Associado para a Sustentabilidade e Tecnologia em Regi\u00f5es de Montanha (SusTEC), Instituto Polit\u00e9cnico de Bragan\u00e7a, Campus de Santa Apol\u00f3nia, 5300-253 Bragan\u00e7a, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6801-4578","authenticated-orcid":false,"given":"Ricardo C.","family":"Calhelha","sequence":"additional","affiliation":[{"name":"Centro de Investiga\u00e7\u00e3o da Montanha (CIMO), Instituto Polit\u00e9cnico de Bragan\u00e7a, Campus de Santa Apol\u00f3nia, 5300-253 Bragan\u00e7a, Portugal"},{"name":"Laborat\u00f3rio Associado para a Sustentabilidade e Tecnologia em Regi\u00f5es de Montanha (SusTEC), Instituto Polit\u00e9cnico de Bragan\u00e7a, Campus de Santa Apol\u00f3nia, 5300-253 Bragan\u00e7a, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2024,8,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.actbio.2022.05.043","article-title":"Potential of Plant Secondary Metabolite-Based Polymers to Enhance Wound Healing","volume":"147","author":"Krishna","year":"2022","journal-title":"Acta Biomater."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"115839","DOI":"10.1016\/j.carbpol.2020.115839","article-title":"Wound Healing and Antimicrobial Effect of Active Secondary Metabolites in Chitosan-Based Wound Dressings: A Review","volume":"233","author":"Moeini","year":"2020","journal-title":"Carbohydr. 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