{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T21:41:25Z","timestamp":1774647685691,"version":"3.50.1"},"reference-count":170,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2015,8,14]],"date-time":"2015-08-14T00:00:00Z","timestamp":1439510400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Marine Drugs"],"abstract":"<jats:p>Epidemiological studies have shown a relation between antioxidants and the prevention of several chronic diseases. Microalgae are a potential novel source of bioactive molecules, including a wide range of different carotenoids that can be used as nutraceuticals, food supplements and novel food products. The objective of this review is (i) to update the research that has been carried out on the most known carotenoids produced by marine microalgae, including reporting on their high potentialities to produce other less known important compounds; (ii) to compile the work that has been done in order to establish some relationship between carotenoids and oxidative protection and treatment; (iii) to summarize the association of oxidative stress and the various reactive species including free radicals with several human diseases; and (iv) to provide evidence of the potential of carotenoids from marine microalgae to be used as therapeutics to treat or prevent these oxidative stress-related diseases.<\/jats:p>","DOI":"10.3390\/md13085128","type":"journal-article","created":{"date-parts":[[2015,8,18]],"date-time":"2015-08-18T02:36:16Z","timestamp":1439865376000},"page":"5128-5155","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":201,"title":["Carotenoids from Marine Microalgae: A Valuable Natural Source for the Prevention of Chronic Diseases"],"prefix":"10.3390","volume":"13","author":[{"given":"Maria","family":"Raposo","sequence":"first","affiliation":[{"name":"CBQF\u2014Centro de Biotecnologia e Qu\u00edmica Fina\u2014Laborat\u00f3rio Associado, Escola Superior de Biotecnologia, Universidade Cat\u00f3lica Portuguesa\/Porto, Rua Arquiteto Lob\u00e3o Vital, Porto 4202-401, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1059-9649","authenticated-orcid":false,"given":"Alcina","family":"De Morais","sequence":"additional","affiliation":[{"name":"CBQF\u2014Centro de Biotecnologia e Qu\u00edmica Fina\u2014Laborat\u00f3rio Associado, Escola Superior de Biotecnologia, Universidade Cat\u00f3lica Portuguesa\/Porto, Rua Arquiteto Lob\u00e3o Vital, Porto 4202-401, Portugal"}]},{"given":"Rui","family":"De Morais","sequence":"additional","affiliation":[{"name":"CBQF\u2014Centro de Biotecnologia e Qu\u00edmica Fina\u2014Laborat\u00f3rio Associado, Escola Superior de Biotecnologia, Universidade Cat\u00f3lica Portuguesa\/Porto, Rua Arquiteto Lob\u00e3o Vital, Porto 4202-401, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2015,8,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"459","DOI":"10.33549\/physiolres.931844","article-title":"Some current insights into oxidative stress","volume":"59","author":"Durackova","year":"2010","journal-title":"Physiol. 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