{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T02:41:02Z","timestamp":1771036862357,"version":"3.50.1"},"reference-count":34,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2024,4,9]],"date-time":"2024-04-09T00:00:00Z","timestamp":1712620800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National project MAR2020","award":["I9+ProAlga-16-01-03-FMP-0011"],"award-info":[{"award-number":["I9+ProAlga-16-01-03-FMP-0011"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Marine Drugs"],"abstract":"<jats:p>The nutritional and bioactive value of seaweeds is widely recognized, making them a valuable food source. To use seaweeds as food, drying and thermal treatments are required, but these treatments may have a negative impact on valuable bioactive compounds. In this study, the effects of dehydration, rehydration, and thermal treatment on the bioactive compounds (carotenoids, phycobiliproteins, total phenolic content (TPC), total flavonoids content (TFC)), antioxidant (ABTS and DPPH radical scavenging activities) and anti-Alzheimer\u2019s (Acetylcholinesterase (AchE) inhibitory activities, and color properties of Porphyra umbilicalis and Porphyra linearis seaweeds were evaluated. The results revealed significant reductions in carotenoids, TPC, TFC, and antioxidant activities after the seaweeds\u2019 processing, with differences observed between species. Thermal treatment led to the most pronounced reductions in bioactive compound contents and antioxidant activity. AchE inhibitory activity remained relatively high in all samples, with P. umbilicalis showing higher activity than P. linearis. Changes in color (\u0394E) were significant after seaweeds\u2019 dehydration, rehydration and thermal treatment, especially in P. umbilicalis. Overall, optimizing processing methods is crucial for preserving the bioactive compounds and biological activities of seaweeds, thus maximizing their potential as sustainable and nutritious food sources or as nutraceutical ingredients.<\/jats:p>","DOI":"10.3390\/md22040166","type":"journal-article","created":{"date-parts":[[2024,4,10]],"date-time":"2024-04-10T03:07:48Z","timestamp":1712718468000},"page":"166","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Dehydration, Rehydration and Thermal Treatment: Effect on Bioactive Compounds of Red Seaweeds Porphyra umbilicalis and Porphyra linearis"],"prefix":"10.3390","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3772-2050","authenticated-orcid":false,"given":"Carla","family":"Pires","sequence":"first","affiliation":[{"name":"Division of Aquaculture, Upgrading and Biospropecting (DivAV), Department for the Sea and Marine Resources, Portuguese Institute for the Sea and Atmosphere (IPMA), Av. Dr. Alfredo Magalh\u00e3es Ramalho 6, 1495-165 Lisbon, Portugal"},{"name":"Interdisciplinary Center of Marine and Environmental Research (CIIMAR), University of Porto, Terminal de Cruzeiros de Leix\u00f5es, Av. General Norton de Matos s\/n, 4450-208 Matosinhos, Portugal"}]},{"given":"Maria","family":"Sapatinha","sequence":"additional","affiliation":[{"name":"Division of Aquaculture, Upgrading and Biospropecting (DivAV), Department for the Sea and Marine Resources, Portuguese Institute for the Sea and Atmosphere (IPMA), Av. Dr. Alfredo Magalh\u00e3es Ramalho 6, 1495-165 Lisbon, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4272-865X","authenticated-orcid":false,"given":"Rog\u00e9rio","family":"Mendes","sequence":"additional","affiliation":[{"name":"Division of Aquaculture, Upgrading and Biospropecting (DivAV), Department for the Sea and Marine Resources, Portuguese Institute for the Sea and Atmosphere (IPMA), Av. Dr. Alfredo Magalh\u00e3es Ramalho 6, 1495-165 Lisbon, Portugal"},{"name":"Interdisciplinary Center of Marine and Environmental Research (CIIMAR), University of Porto, Terminal de Cruzeiros de Leix\u00f5es, Av. General Norton de Matos s\/n, 4450-208 Matosinhos, Portugal"}]},{"given":"Narcisa M.","family":"Bandarra","sequence":"additional","affiliation":[{"name":"Division of Aquaculture, Upgrading and Biospropecting (DivAV), Department for the Sea and Marine Resources, Portuguese Institute for the Sea and Atmosphere (IPMA), Av. Dr. Alfredo Magalh\u00e3es Ramalho 6, 1495-165 Lisbon, Portugal"},{"name":"Interdisciplinary Center of Marine and Environmental Research (CIIMAR), University of Porto, Terminal de Cruzeiros de Leix\u00f5es, Av. General Norton de Matos s\/n, 4450-208 Matosinhos, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6316-4676","authenticated-orcid":false,"given":"Amparo","family":"Gon\u00e7alves","sequence":"additional","affiliation":[{"name":"Division of Aquaculture, Upgrading and Biospropecting (DivAV), Department for the Sea and Marine Resources, Portuguese Institute for the Sea and Atmosphere (IPMA), Av. Dr. Alfredo Magalh\u00e3es Ramalho 6, 1495-165 Lisbon, Portugal"},{"name":"Interdisciplinary Center of Marine and Environmental Research (CIIMAR), University of Porto, Terminal de Cruzeiros de Leix\u00f5es, Av. General Norton de Matos s\/n, 4450-208 Matosinhos, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2024,4,9]]},"reference":[{"key":"ref_1","unstructured":"Cai, J., Lovatelli, A., Aguilar-Manjarrez, J., Cornish, L., Dabbadie, L., Desrochers, A., Diffey, S., Garrido Gamarro, E., Geehan, J., and Hurtado, A. (2021). 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