{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T17:05:42Z","timestamp":1776877542187,"version":"3.51.2"},"reference-count":106,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2024,7,22]],"date-time":"2024-07-22T00:00:00Z","timestamp":1721606400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Ministerio de Ciencia e Innovaci\u00f3n, Agencia Estatal de Investigaci\u00f3n","award":["PID2020-116076RJ-I00"],"award-info":[{"award-number":["PID2020-116076RJ-I00"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Marine Drugs"],"abstract":"<jats:p>The marine kingdom is an important source of a huge variety of scaffolds inspiring the design of new drugs. The complex molecules found in the oceans present a great challenge to organic and medicinal chemists. However, the wide variety of biological activities they can display is worth the effort. In this article, we present an overview of different seaweeds as potential sources of bioactive pigments with activity against neurodegenerative diseases, especially due to their neuroprotective effects. Along with a broad introduction to seaweed as a source of bioactive pigments, this review is especially focused on astaxanthin and fucoxanthin as potential neuroprotective and\/or anti-neurodegenerative agents. PubMed and SciFinder were used as the main sources to search and select the most relevant scientific articles within the field.<\/jats:p>","DOI":"10.3390\/md22070327","type":"journal-article","created":{"date-parts":[[2024,7,22]],"date-time":"2024-07-22T12:20:38Z","timestamp":1721650838000},"page":"327","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Seaweeds as Source of Bioactive Pigments with Neuroprotective and\/or Anti-Neurodegenerative Activities: Astaxanthin and Fucoxanthin"],"prefix":"10.3390","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0515-6720","authenticated-orcid":false,"given":"Estela","family":"Guardado Yordi","sequence":"first","affiliation":[{"name":"Universidad Estatal Amaz\u00f3nica, 160101 Puyo, Ecuador"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3978-7982","authenticated-orcid":false,"given":"Amaury","family":"P\u00e9rez Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Universidad Estatal Amaz\u00f3nica, 160101 Puyo, Ecuador"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4771-8912","authenticated-orcid":false,"given":"Matteo","family":"Radice","sequence":"additional","affiliation":[{"name":"Universidad Estatal Amaz\u00f3nica, 160101 Puyo, Ecuador"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6015-9871","authenticated-orcid":false,"given":"Laura","family":"Scalvenzi","sequence":"additional","affiliation":[{"name":"Universidad Estatal Amaz\u00f3nica, 160101 Puyo, Ecuador"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1048-7126","authenticated-orcid":false,"given":"Reinier","family":"Abreu-Naranjo","sequence":"additional","affiliation":[{"name":"Universidad Estatal Amaz\u00f3nica, 160101 Puyo, Ecuador"}]},{"given":"Eugenio","family":"Uriarte","sequence":"additional","affiliation":[{"name":"Departamento de Qu\u00edmica Org\u00e1nica, Facultad de Farmacia, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain"}]},{"given":"Lourdes","family":"Santana","sequence":"additional","affiliation":[{"name":"Departamento de Qu\u00edmica Org\u00e1nica, Facultad de Farmacia, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3470-8299","authenticated-orcid":false,"given":"Maria Joao","family":"Matos","sequence":"additional","affiliation":[{"name":"Departamento de Qu\u00edmica Org\u00e1nica, Facultad de Farmacia, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain"}]}],"member":"1968","published-online":{"date-parts":[[2024,7,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"101703","DOI":"10.1016\/j.arr.2022.101703","article-title":"Prevalence of dementia in latin america and caribbean countries: Systematic review and meta-analyses exploring age, sex, rurality, and education as possible determinants","volume":"81","author":"Ribeiro","year":"2022","journal-title":"Ageing Res. 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