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101079147"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Marine Drugs"],"abstract":"<jats:p>The formation of amyloid-like structures is commonly linked to neurodegenerative diseases, such as Parkinson\u2019s and Alzheimer\u2019s. However, proteins can form amyloid-like structures in non-pathological contexts, referred to as functional amyloids. We review the current knowledge on the evolutionary and ecological significance of the presence of proteins presenting amyloid-like structures in adhesive secretions (both permanent and non-permanent) produced by several marine organisms; in addition, we analyze the molecular and structural properties that make them well suited for this task and their possible biomimetic and industrial applications.<\/jats:p>","DOI":"10.3390\/md23090363","type":"journal-article","created":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T12:33:32Z","timestamp":1758285212000},"page":"363","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Amyloid-like Structures in Marine Adhesive Proteins"],"prefix":"10.3390","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3594-5915","authenticated-orcid":false,"given":"Mariana Rodrigues","family":"Santos","sequence":"first","affiliation":[{"name":"BioISI\u2014Instituto de Biosistemas e Ci\u00eancias integrativas, Faculdade de Ci\u00eancias, Universidade de Lisboa, 1749-016 Lisboa, Portugal"},{"name":"Centro de Ci\u00eancias do Mar e do Ambiente (MARE), ARNET\u2014Aquatic Research Network, Departamento de Biologia Animal, Faculdade de Ci\u00eancias, Universidade de Lisboa, 1749-016 Lisboa, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1724-9545","authenticated-orcid":false,"given":"B\u00e1rbara Joana","family":"Henriques","sequence":"additional","affiliation":[{"name":"BioISI\u2014Instituto de Biosistemas e Ci\u00eancias integrativas, Faculdade de Ci\u00eancias, Universidade de Lisboa, 1749-016 Lisboa, Portugal"},{"name":"Departamento de Qu\u00edmica e Bioqu\u00edmica, Faculdade de Ci\u00eancias, Universidade de Lisboa, 1749-016 Lisboa, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7720-6806","authenticated-orcid":false,"given":"Romana","family":"Santos","sequence":"additional","affiliation":[{"name":"Centro de Ci\u00eancias do Mar e do Ambiente (MARE), ARNET\u2014Aquatic Research Network, Departamento de Biologia Animal, Faculdade de Ci\u00eancias, Universidade de Lisboa, 1749-016 Lisboa, Portugal"},{"name":"Departamento de Biologia, Faculdade de Ci\u00eancias, Universidade de Lisboa, 1749-016 Lisboa, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2025,9,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.tibs.2007.03.003","article-title":"Functional amyloid\u2014From bacteria to humans","volume":"32","author":"Fowler","year":"2007","journal-title":"Trends Biochem. 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