{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T12:08:50Z","timestamp":1769602130279,"version":"3.49.0"},"reference-count":49,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2023,1,20]],"date-time":"2023-01-20T00:00:00Z","timestamp":1674172800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"national funds","award":["UIDB\/04423\/2020"],"award-info":[{"award-number":["UIDB\/04423\/2020"]}]},{"name":"national funds","award":["UIDP\/04423\/2020"],"award-info":[{"award-number":["UIDP\/04423\/2020"]}]},{"name":"national funds","award":["UIDB\/000081\/2020"],"award-info":[{"award-number":["UIDB\/000081\/2020"]}]},{"name":"national funds","award":["LA\/P\/0056\/2020"],"award-info":[{"award-number":["LA\/P\/0056\/2020"]}]},{"name":"R&amp;D Units CIQUP","award":["UIDB\/04423\/2020"],"award-info":[{"award-number":["UIDB\/04423\/2020"]}]},{"name":"R&amp;D Units CIQUP","award":["UIDP\/04423\/2020"],"award-info":[{"award-number":["UIDP\/04423\/2020"]}]},{"name":"R&amp;D Units CIQUP","award":["UIDB\/000081\/2020"],"award-info":[{"award-number":["UIDB\/000081\/2020"]}]},{"name":"R&amp;D Units CIQUP","award":["LA\/P\/0056\/2020"],"award-info":[{"award-number":["LA\/P\/0056\/2020"]}]},{"name":"Associated Laboratory IMS","award":["UIDB\/04423\/2020"],"award-info":[{"award-number":["UIDB\/04423\/2020"]}]},{"name":"Associated Laboratory IMS","award":["UIDP\/04423\/2020"],"award-info":[{"award-number":["UIDP\/04423\/2020"]}]},{"name":"Associated Laboratory IMS","award":["UIDB\/000081\/2020"],"award-info":[{"award-number":["UIDB\/000081\/2020"]}]},{"name":"Associated Laboratory IMS","award":["LA\/P\/0056\/2020"],"award-info":[{"award-number":["LA\/P\/0056\/2020"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microorganisms"],"abstract":"<jats:p>(1) Background: Superficial, including cutaneous and mucocutaneous infections are a current public health problem with universal distribution. One of the main concerns, in the present\/future, is fungal\/bacterial infections by resistant microorganisms. This study aimed to verify if decoctions of coptidis (Coptis chinensis, Ranunculaceae family), neem (Azadirachta indica, Meliaceae family), and their essential oils (EOs), as well as the EO of manuka (Leptospermum scoparium, Myrtaceae family) have antimicrobial activity against prevalent species of microorganisms responsible for superficial infections. (2) Methods: The antimicrobial activity was determined by the minimum inhibitory concentration (MIC), using broth microdilution method, and minimum lethal concentration (MLC) was determined from subculture of MIC plates. (3) Results: C. chinensis EO and decoction demonstrated some antifungal action against the yeasts and dermatophytes tested. Greatest bactericidal effect against Propionibacterium acnes and some action against Staphylococcus aureus was observed. For A. indica only EO proved activity against dermatophytes and P. acnes. L. scoparium EO showed the broadest antimicrobial spectrum with activity against bacteria, yeasts, and dermatophytes showing greater activity against P. acnes and S. aureus. (4) Conclusions: C. chinensis (EO\/decoction), EOs of L. scoparium and A. indica proved in vitro efficacy against fungal, bacterial, or mixed agents of superficial infections, either by sensitive or resistant strains.<\/jats:p>","DOI":"10.3390\/microorganisms11020272","type":"journal-article","created":{"date-parts":[[2023,1,20]],"date-time":"2023-01-20T02:43:29Z","timestamp":1674182609000},"page":"272","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Antimicrobial Activity of Some Medicinal Herbs to the Treatment of Cutaneous and Mucocutaneous Infections: Preliminary Research"],"prefix":"10.3390","volume":"11","author":[{"given":"Alexandra","family":"Noites","sequence":"first","affiliation":[{"name":"Laboratory of Applied Physiology, ICBAS\u2014Institute of Biomedical Sciences Abel Salazar, University of Porto, 4099-002 Porto, Portugal"}]},{"given":"Iara","family":"Borges","sequence":"additional","affiliation":[{"name":"Laboratory of Microbiology and Biological Sciences Department, FFUP\u2014Faculty of Pharmacy of University of Porto, University of Porto, 4099-002 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5464-8206","authenticated-orcid":false,"given":"Bruno","family":"Ara\u00fajo","sequence":"additional","affiliation":[{"name":"Laboratory of Microbiology and Biological Sciences Department, FFUP\u2014Faculty of Pharmacy of University of Porto, University of Porto, 4099-002 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8478-3441","authenticated-orcid":false,"given":"Joaquim C. G. Esteves","family":"da Silva","sequence":"additional","affiliation":[{"name":"Research Center in Chemistry (CIQUP), Institute of Molecular Sciences (IMS), Department of Geosciences, Environment and Spatial Plannings, Rua do Campo Alegre s\/n, 4169-007 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1699-6338","authenticated-orcid":false,"given":"Nat\u00e1lia M.","family":"de Oliveira","sequence":"additional","affiliation":[{"name":"Laboratory of Applied Physiology, ICBAS\u2014Institute of Biomedical Sciences Abel Salazar, University of Porto, 4099-002 Porto, Portugal"},{"name":"CBSin\u2014Center of BioSciences in Integrative Health, 4250-105 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4570-5445","authenticated-orcid":false,"given":"Jorge","family":"Machado","sequence":"additional","affiliation":[{"name":"Laboratory of Applied Physiology, ICBAS\u2014Institute of Biomedical Sciences Abel Salazar, University of Porto, 4099-002 Porto, Portugal"},{"name":"CBSin\u2014Center of BioSciences in Integrative Health, 4250-105 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2948-5809","authenticated-orcid":false,"given":"Eug\u00e9nia","family":"Pinto","sequence":"additional","affiliation":[{"name":"Laboratory of Microbiology and Biological Sciences Department, FFUP\u2014Faculty of Pharmacy of University of Porto, University of Porto, 4099-002 Porto, Portugal"},{"name":"CIIMAR\u2014Interdisciplinary Centre of Marine and Environmental Research, University of Porto, 4450-208 Porto, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.jmii.2013.12.009","article-title":"Investigations of kanuka and manuka essential oils for in vitro treatment of disease and cellular inflammation caused by infectious microorganisms","volume":"49","author":"Chen","year":"2016","journal-title":"J. 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