{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T05:05:27Z","timestamp":1771477527668,"version":"3.50.1"},"reference-count":11,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2021,12,17]],"date-time":"2021-12-17T00:00:00Z","timestamp":1639699200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microorganisms"],"abstract":"<jats:p>Despite the enormous progress made in the last few decades, infectious diseases still represent a huge challenge to human society and health systems, as evidenced by the recent SARS-CoV-2 pandemic [...]<\/jats:p>","DOI":"10.3390\/microorganisms9122606","type":"journal-article","created":{"date-parts":[[2021,12,20]],"date-time":"2021-12-20T02:50:18Z","timestamp":1639968618000},"page":"2606","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Special Issue: From Host\u2013Pathogen Interaction to Host-Directed Therapies"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7657-2118","authenticated-orcid":false,"given":"Maria Salom\u00e9","family":"Gomes","sequence":"first","affiliation":[{"name":"i3S\u2014Instituto de Investiga\u00e7\u00e3o e Inova\u00e7\u00e3o em Sa\u00fade, Universidade do Porto, 4200-135 Porto, Portugal"},{"name":"IBMC\u2014Instituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135 Porto, Portugal"},{"name":"ICBAS\u2014Instituto de Ci\u00eancias Biom\u00e9dicas Abel Salazar, Universidade do Porto, 4050-313 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4271-1527","authenticated-orcid":false,"given":"Luisa","family":"Pereira","sequence":"additional","affiliation":[{"name":"i3S\u2014Instituto de Investiga\u00e7\u00e3o e Inova\u00e7\u00e3o em Sa\u00fade, Universidade do Porto, 4200-135 Porto, Portugal"},{"name":"IPATIMUP\u2014Instituto de Patologia e Imunologia Molecular, Universidade do Porto, 4200-135 Porto, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2021,12,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"P\u00e9rez-Arques, C., Navarro-Mendoza, M.I., Murcia, L., Lax, C., Sanchis, M., Capilla, J., Navarro, E., Garre, V., and Nicol\u00e1s, F.E. (2021). A Mucoralean White Collar-1 Photoreceptor Controls Virulence by Regulating an Intricate Gene Network during Host Interactions. Microorganisms, 9.","DOI":"10.3390\/microorganisms9020459"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Pedro, N., Silva, C.N., Magalh\u00e3es, A.C., Cavadas, B., Rocha, A.M., Moreira, A.C., Gomes, M.S., Silva, D., Sobrinho-Sim\u00f5es, J., and Ramos, A. (2021). Dynamics of a dual SARS-CoV-2 lineage co-infection on a prolonged viral shedding COVID-19 case: Insights into clinical severity and disease duration. Microorganisms, 9.","DOI":"10.3390\/microorganisms9020300"},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Malagnino, V., Teti, E., Compagno, M., Coppola, L., Salpini, R., Svicher, V., Basso, M., Battagin, G., Panese, S., and Rossi, M.C. (2021). HBcAb Positivity Is a Risk Factor for an Increased Detectability of HIV RNA after Switching to a Two-Drug Regimen Lamivudine-Based (2DR-3TC-Based) Treatment: Analysis of a Multicenter Italian Cohort. Microorganisms, 9.","DOI":"10.3390\/microorganisms9020396"},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Rouzine, I.M. (2020). An Evolutionary Model of Progression to AIDS. Microorganisms, 8.","DOI":"10.3390\/microorganisms8111714"},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Cavadas, B., Camacho, R., Ferreira, J.C., Ferreira, R.M., Figueiredo, C., Brazma, A., Fonseca, N.A., and Pereira, L. (2020). Gastric Microbiome Diversities in Gastric Cancer Patients from Europe and Asia Mimic the Human Population Structure and Are Partly Driven by Microbiome Quantitative Trait Loci. Microorganisms, 8.","DOI":"10.3390\/microorganisms8081196"},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Cavadas, B., Leite, M., Pedro, N., Magalh\u00e3es, A.C., Melo, J., Correia, M., M\u00e1ximo, V., Camacho, R., Fonseca, N.A., and Figueiredo, C. (2021). Shedding Light on the African Enigma: In Vitro Testing of Homo sapiens-Helicobacter pylori Coevolution. Microorganisms, 9.","DOI":"10.3390\/microorganisms9020240"},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Rito, T., Ferreira, J., Cavadas, B., Soares, P., Oliveira, O., Richards, M.B., Duarte, R., Pereira, L., and Correia-Neves, M. (2019). Association of Leukotriene A4 Hydrolase with Tuberculosis Susceptibility Using Genomic Data in Portugal. Microorganisms, 7.","DOI":"10.3390\/microorganisms7120650"},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Matos, R., Fonseca, K.L., Mereiter, S., Maceiras, A.R., Gomes, J., Vilaplana, C., Gartner, F., Rodrigues, P.N.S., Reis, C.A., and Saraiva, M. (2021). Mycobacterium tuberculosis Infection Up-Regulates Sialyl Lewis X Expression in the Lung Epithelium. Microorganisms, 9.","DOI":"10.3390\/microorganisms9010099"},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Moreira, A.C., Mesquita, G., and Gomes, M.S. (2020). Ferritin: An Inflammatory Player Keeping Iron at the Core of Pathogen-Host Interactions. Microorganisms, 8.","DOI":"10.3390\/microorganisms8040589"},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Oliveira, T.C., Gomes, M.S., and Gomes, A.C. (2020). The Crossroads between Infection and Bone Loss. Microorganisms, 8.","DOI":"10.3390\/microorganisms8111765"},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Heimesaat, M.M., Mousavi, S., Weschka, D., and Bereswill, S. (2021). Anti-Pathogenic and Immune-Modulatory Effects of Peroral Treatment with Cardamom Essential Oil in Acute Murine Campylobacteriosis. Microorganisms, 9.","DOI":"10.3390\/microorganisms9010169"}],"container-title":["Microorganisms"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-2607\/9\/12\/2606\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T07:50:19Z","timestamp":1760169019000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-2607\/9\/12\/2606"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,17]]},"references-count":11,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2021,12]]}},"alternative-id":["microorganisms9122606"],"URL":"https:\/\/doi.org\/10.3390\/microorganisms9122606","relation":{},"ISSN":["2076-2607"],"issn-type":[{"value":"2076-2607","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,17]]}}}