{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T21:36:19Z","timestamp":1766180179284,"version":"build-2065373602"},"reference-count":26,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2008,6,12]],"date-time":"2008-06-12T00:00:00Z","timestamp":1213228800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Walnut leaves from nine different cultivars (Arco, Franquette, Hartley, Lara, Marbot, Mayette, Meylannaise, Parisienne and Rego) were studied for their phenolic compounds. Samples were harvested along three consecutive years, at two different geographical locations, in order to evaluate if significant differences in the phenolics composition can be related with genetic, climatic or geographical factors. Nine compounds (3-caffeoylquinic, 3-p-coumaroylquinic and 4-p-coumaroylquinic acids, quercetin 3- galactoside, quercetin 3-arabinoside, quercetin 3-xyloside, quercetin 3-rhamnoside, a quercetin 3-pentoside derivative and a kaempferol 3-pentoside derivative) were quantified using an HPLC-DAD methodology. The qualitative profiles were identical for all samples, but differences were observed in terms of individual compounds\u2019 contents. Multivariate statistical analysis was carried out, showing that significant differences exist among production years, which can be related to climatic reasons.<\/jats:p>","DOI":"10.3390\/molecules13061321","type":"journal-article","created":{"date-parts":[[2008,7,2]],"date-time":"2008-07-02T02:24:35Z","timestamp":1214965475000},"page":"1321-1332","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Do Cultivar, Geographical Location and Crop Season Influence Phenolic Profile of Walnut Leaves?"],"prefix":"10.3390","volume":"13","author":[{"given":"Joana S.","family":"Amaral","sequence":"first","affiliation":[{"name":"REQUIMTE, Servi\u00e7o de Farmacognosia, Faculdade de Farm\u00e1cia, Universidade do Porto, R. An\u00edbal Cunha, 164, 4099-030 Porto, Portugal"},{"name":"Escola Superior de Tecnologia e de Gest\u00e3o, Instituto Polit\u00e9cnico de Bragan\u00e7a, Quinta de Sta. Apol\u00f3nia, Apartado 134, 5301-857 Bragan\u00e7a, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0740-4396","authenticated-orcid":false,"given":"Patr\u00edcia","family":"Valent\u00e3o","sequence":"additional","affiliation":[{"name":"REQUIMTE, Servi\u00e7o de Farmacognosia, Faculdade de Farm\u00e1cia, Universidade do Porto, R. An\u00edbal Cunha, 164, 4099-030 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9764-3920","authenticated-orcid":false,"given":"Paula B.","family":"Andrade","sequence":"additional","affiliation":[{"name":"REQUIMTE, Servi\u00e7o de Farmacognosia, Faculdade de Farm\u00e1cia, Universidade do Porto, R. An\u00edbal Cunha, 164, 4099-030 Porto, Portugal"}]},{"given":"Rui C.","family":"Martins","sequence":"additional","affiliation":[{"name":"Centre for Biological Engineering, University of Minho, Campus of Gualtar, 4710-057 Braga, Portugal"}]},{"given":"Rosa M.","family":"Seabra","sequence":"additional","affiliation":[{"name":"REQUIMTE, Servi\u00e7o de Farmacognosia, Faculdade de Farm\u00e1cia, Universidade do Porto, R. An\u00edbal Cunha, 164, 4099-030 Porto, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2008,6,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"7698","DOI":"10.1021\/jf030451d","article-title":"Determination of sterol and fatty acid compositions, oxidative stability, and nutritional value of six walnut (Juglans regia L.) cultivars grown in Portugal. J. 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