{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T03:45:56Z","timestamp":1773114356388,"version":"3.50.1"},"reference-count":118,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2011,3,25]],"date-time":"2011-03-25T00:00:00Z","timestamp":1301011200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Sheep, cattle and goat are domestic ruminants of significant economic interest in the Mediterranean region. Although sharing the same pasture ranges, they ingest different plants and plant parts and, consequently different levels of tannins. This suggests an ability to detect and adapt ingestion according to animal physiological limits of tolerance for plant secondary metabolites. This review will detail the effects of dietary tannins on feeding behavior, and the role of the oral cavity in this process, with focus on such ruminant species. The role of salivary protein profile in tannin perception in the oral cavity, and as a defense mechanism, will be discussed.<\/jats:p>","DOI":"10.3390\/molecules16042766","type":"journal-article","created":{"date-parts":[[2011,3,25]],"date-time":"2011-03-25T11:14:25Z","timestamp":1301051665000},"page":"2766-2784","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":58,"title":["The Effect of Tannins on Mediterranean Ruminant Ingestive Behavior: The Role of the Oral Cavity"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9370-1337","authenticated-orcid":false,"given":"Elsa","family":"Lamy","sequence":"first","affiliation":[{"name":"Instituto de Ci\u00eancias Agr\u00e1rias e Ambientais Mediterr\u00e2nicas (ICAAM), Universidade de \u00c9vora, \u00c9vora, Portugal"},{"name":"Escola Superior de Hotelaria e Turismo do Estoril (ESHTE), Estoril, Portugal"}]},{"given":"Harshadrai","family":"Rawel","sequence":"additional","affiliation":[{"name":"Institute of Nutritional Science, University of Potsdam, Nuthetal (OT Bergholz-Rehbr\u00fccke), Germany"}]},{"given":"Florian J.","family":"Schweigert","sequence":"additional","affiliation":[{"name":"Institute of Nutritional Science, University of Potsdam, Nuthetal (OT Bergholz-Rehbr\u00fccke), Germany"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8301-7702","authenticated-orcid":false,"given":"Fernando","family":"Capela e Silva","sequence":"additional","affiliation":[{"name":"Instituto de Ci\u00eancias Agr\u00e1rias e Ambientais Mediterr\u00e2nicas (ICAAM), Universidade de \u00c9vora, \u00c9vora, Portugal"},{"name":"Departamento de Biologia, Universidade de \u00c9vora, \u00c9vora, Portugal"}]},{"given":"Ana","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Instituto de Ci\u00eancias Agr\u00e1rias e Ambientais Mediterr\u00e2nicas (ICAAM), Universidade de \u00c9vora, \u00c9vora, Portugal"}]},{"given":"Ana Rodrigues","family":"Costa","sequence":"additional","affiliation":[{"name":"Instituto de Ci\u00eancias Agr\u00e1rias e Ambientais Mediterr\u00e2nicas (ICAAM), Universidade de \u00c9vora, \u00c9vora, Portugal"},{"name":"Departamento de Qu\u00edmica, Universidade de \u00c9vora, \u00c9vora, Portugal"}]},{"given":"C\u00e9lia","family":"Antunes","sequence":"additional","affiliation":[{"name":"Instituto de Ci\u00eancias Agr\u00e1rias e Ambientais Mediterr\u00e2nicas (ICAAM), Universidade de \u00c9vora, \u00c9vora, Portugal"},{"name":"Departamento de Qu\u00edmica, Universidade de \u00c9vora, \u00c9vora, Portugal"},{"name":"Centro de Neuroci\u00eancias e Biologia Celular (CNBC), Universidade de Coimbra, Coimbra, Portugal"}]},{"given":"Andr\u00e9 Martinho","family":"Almeida","sequence":"additional","affiliation":[{"name":"Instituto de Investiga\u00e7\u00e3o Cient\u00edfica Tropical (IICT) & CIISA \u2013 Centro Interdisciplinar de Investiga\u00e7\u00e3o em Sanidade Animal. CVZ - Centro de Veterin\u00e1ria e Zootecnia, Faculdade de Medicina Veterin\u00e1ria, Lisboa, Portugal"},{"name":"Instituto de Tecnologia Qu\u00edmica e Biol\u00f3gica\/Universidade Nova de Lisboa (ITQB\/UNL), Oeiras, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6143-4203","authenticated-orcid":false,"given":"Ana Varela","family":"Coelho","sequence":"additional","affiliation":[{"name":"Departamento de Qu\u00edmica, Universidade de \u00c9vora, \u00c9vora, Portugal"},{"name":"Instituto de Tecnologia Qu\u00edmica e Biol\u00f3gica\/Universidade Nova de Lisboa (ITQB\/UNL), Oeiras, Portugal"}]},{"given":"Elvira","family":"Sales-Baptista","sequence":"additional","affiliation":[{"name":"Instituto de Ci\u00eancias Agr\u00e1rias e Ambientais Mediterr\u00e2nicas (ICAAM), Universidade de \u00c9vora, \u00c9vora, Portugal"},{"name":"Departamento de Zootecnia, Universidade de \u00c9vora, \u00c9vora, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2011,3,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"3029","DOI":"10.2527\/1996.74123029x","article-title":"Integration of regulatory signals controlling forage intake in ruminants","volume":"74","author":"Forbes","year":"1996","journal-title":"J. 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