{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T06:33:01Z","timestamp":1777789981369,"version":"3.51.4"},"reference-count":22,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2014,7,3]],"date-time":"2014-07-03T00:00:00Z","timestamp":1404345600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Bar adsorptive microextraction combined with liquid desorption followed by high performance liquid chromatography with diode array detection (BA\u00b5E-LD\/HPLC-DAD) is proposed for the determination of trace levels of five phenol compounds (3-nitrophenol, 4-nitrophenol, bisphenol-A, 4-n-octylphenol and 4-n-nonylphenol) in surface water matrices. By using a polystyrene-divinylbenzene copolymer (PS-DVB) sorbent phase, high selectivity and efficiency is achieved even against polydimethylsiloxane through stir bar sorptive extraction. Assays performed by BA\u00b5E(PS-DVB)-LD\/HPLC-DAD on 25 mL water samples spiked at the 10.0 \u00b5g\/L levels yielded recoveries over 88.0% \u00b1 5.7% for all five analytes, under optimized experimental conditions. The analytical performance showed good precision (RSD &lt; 15%), detection limits of 0.25 \u00b5g\/L and linear dynamic ranges (1.0\u201325.0 \u03bcg\/L) with determination coefficient higher than 0.9904. By using the standard addition method, the application of the present method to surface water matrices allowed very good performances at the trace level. The proposed methodology proved to be a suitable alternative to monitor phenol compounds in surface water matrices, showing to be easy to implement, reliable, sensitive and requiring a low sample volume.<\/jats:p>","DOI":"10.3390\/molecules19079369","type":"journal-article","created":{"date-parts":[[2014,7,3]],"date-time":"2014-07-03T11:13:17Z","timestamp":1404385997000},"page":"9369-9379","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Determination of Phenol Compounds In Surface Water Matrices by Bar Adsorptive Microextraction-High Performance Liquid Chromatography-Diode Array Detection"],"prefix":"10.3390","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9879-1565","authenticated-orcid":false,"given":"Nuno","family":"Neng","sequence":"first","affiliation":[{"name":"University of Lisbon, Faculty of Sciences, Chemistry and Biochemistry Department and Center of Chemistry and Biochemistry, Campo Grande Ed. C8, 1749-016 Lisbon, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5785-6780","authenticated-orcid":false,"given":"Jos\u00e9","family":"Nogueira","sequence":"additional","affiliation":[{"name":"University of Lisbon, Faculty of Sciences, Chemistry and Biochemistry Department and Center of Chemistry and Biochemistry, Campo Grande Ed. C8, 1749-016 Lisbon, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2014,7,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"4614","DOI":"10.1021\/ac200915r","article-title":"Water Analysis: Emerging Contaminants and Current Issues","volume":"83","author":"Richardson","year":"2011","journal-title":"Anal. Chem."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"2953","DOI":"10.1016\/S0043-1354(03)00073-3","article-title":"Continuous biotransformation and removal of nitrophenols under denitrifying conditions","volume":"37","author":"Karim","year":"2003","journal-title":"Water Res."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/j.chroma.2008.06.037","article-title":"Analytical methods for the determination of bisphenol A in food","volume":"1216","author":"Rubio","year":"2009","journal-title":"J. Chromatogr. A"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.chroma.2004.03.040","article-title":"Simultaneous determination of alkylphenols and bisphenol A in river water by stir bar sorptive extraction with in situ acetylation and thermal desorption-gas chromatography-mass spectrometry","volume":"1038","author":"Nakamura","year":"2004","journal-title":"J. Chromatogr. A"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.envint.2011.04.010","article-title":"Bisphenol A (BPA) in China: A review of sources, environmental levels, and potential human health impacts","volume":"42","author":"Huang","year":"2012","journal-title":"Environ. Int."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.marpolbul.2013.05.014","article-title":"Detection of nonylphenol and persistent organic pollutants in fish from the North Pacific Central Gyre","volume":"73","author":"Gassel","year":"2013","journal-title":"Mar. Pollut. Bull."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1093\/toxsci\/54.1.154","article-title":"Estrogenic Activity of Octylphenol, Nonylphenol, Bisphenol A and Methoxychlor in Rats","volume":"54","author":"Laws","year":"2000","journal-title":"Toxicol. Sci."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.toxlet.2011.07.032","article-title":"Recent trends in biomonitoring of bisphenol A, 4-t-octylphenol, and 4-nonylphenol","volume":"210","author":"Asimakopoulos","year":"2012","journal-title":"Toxicol. Lett."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.foodcont.2013.03.028","article-title":"Assessment of bisphenol A and bisphenol B in canned vegetables and fruits by gas chromatography-mass spectrometry after QuEChERS and dispersive liquid-liquid microextraction","volume":"33","author":"Cunha","year":"2013","journal-title":"Food Control"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.chroma.2006.04.014","article-title":"Sensitive gas chromatographic-mass spectrometric method for the determination of phthalate esters, alkylphenols, bisphenol A and their chlorinated derivatives in wastewater samples","volume":"1121","author":"Ballesteros","year":"2006","journal-title":"J. Chromatogr. A"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.jpba.2005.05.024","article-title":"Stir bar sorptive extraction with in situ de-conjugation and thermal desorption gas chromatography-mass spectrometry for measurement of 4-nonylphenol glucuronide in human urine sample","volume":"40","author":"Kawaguchi","year":"2006","journal-title":"J. Pharmaceut. Biomed."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.chroma.2004.11.033","article-title":"Stir bar sorptive extraction and trace analysis of alkylphenols in water samples by thermal desorption with in tube silylation and gas chromatography-mass spectrometry","volume":"1062","author":"Kawaguchi","year":"2005","journal-title":"J. Chromatogr. A"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.aca.2003.10.064","article-title":"Determination of 4-nonylphenol and 4-tert-octylphenol in water samples by stir bar sorptive extraction and thermal desorption-gas chromatography-mass spectrometry","volume":"505","author":"Kawaguchi","year":"2004","journal-title":"Anal. Chim. Acta"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0021-9673(04)01015-5","article-title":"Determination of 4-tert-octylphenol and 4-nonylphenol in laboratory animal feed sample by stir bar sorptive extraction followed by liquid desorption and column-switching liquid chromatography\u2013mass spectrometry with solid-phase extraction","volume":"1046","author":"Kawaguchi","year":"2004","journal-title":"J. Chromatogr. A"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.saa.2013.11.015","article-title":"Spectrophotometric and high performance liquid chromatographic methods for sensitive determination of bisphenol A","volume":"122","author":"Zhuang","year":"2014","journal-title":"Spectrochim. Acta"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.aca.2012.10.033","article-title":"Novel sorption-based methodologies for static microextraction analysis: A review on SBSE and related techniques","volume":"757","author":"Nogueira","year":"2012","journal-title":"Anal. Chim. Acta"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"7303","DOI":"10.1016\/j.chroma.2010.09.048","article-title":"Adsorptive micro-extraction techniques\u2014Novel analytical tools for trace levels of polar solutes in aqueous media","volume":"1217","author":"Neng","year":"2010","journal-title":"J. Chromatogr. A"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1007\/s00216-011-5515-0","article-title":"Development of a bar adsorptive micro-extraction-large-volume injection-gas chromatography-mass spectrometric method for pharmaceuticals and personal care products in environmental water matrices","volume":"402","author":"Neng","year":"2012","journal-title":"Anal. Bioanal. Chem."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.chroma.2012.09.047","article-title":"Comparison of the selectivity of different sorbent phases for bar adsorptive microextraction-Application to trace level analysis of fungicides in real matrices","volume":"1265","author":"Almeida","year":"2012","journal-title":"J. Chromatogr. A"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1016\/j.talanta.2010.11.049","article-title":"Powdered activated carbons as effective phases for bar adsorptive micro-extraction (BA\u03bcE) to monitor levels of triazinic herbicides in environmental water matrices","volume":"83","author":"Neng","year":"2011","journal-title":"Talanta"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"6263","DOI":"10.1016\/j.chroma.2011.07.025","article-title":"Cork-based activated carbons as supported adsorbent materials for trace level analysis of ibuprofen and clofibric acid in environmental and biological matrices","volume":"1218","author":"Neng","year":"2011","journal-title":"J. Chromatogr. A"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s00216-002-1266-2","article-title":"Sorptive sample preparation\u2014A review","volume":"373","author":"Baltussen","year":"2002","journal-title":"Anal. Bioanal. 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