{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T02:49:18Z","timestamp":1774493358052,"version":"3.50.1"},"reference-count":204,"publisher":"MDPI AG","issue":"22","license":[{"start":{"date-parts":[[2021,11,17]],"date-time":"2021-11-17T00:00:00Z","timestamp":1637107200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","award":["Norte-01-0145-FEDER-000042."],"award-info":[{"award-number":["Norte-01-0145-FEDER-000042."]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Edible flowers are becoming very popular, as consumers are seeking healthier and more attractive food products that can improve their diet aesthetics and diversify their dietary sources of micronutrients. The great variety of flowers that can be eaten is also associated with high variability in chemical composition, especially in bioactive compounds content that may significantly contribute to human health. The advanced analytical techniques allowed us to reveal the chemical composition of edible flowers and identify new compounds and effects that were not known until recently. Considering the numerous species of edible flowers, the present review aims to categorize the various species depending on their chemical composition and also to present the main groups of compounds that are usually present in the species that are most commonly used for culinary purposes. Moreover, special attention is given to those species that contain potentially toxic or poisonous compounds as their integration in human diets should be carefully considered. In conclusion, the present review provides useful information regarding the chemical composition and the main groups of chemical compounds that are present in the flowers of the most common species.<\/jats:p>","DOI":"10.3390\/molecules26226940","type":"journal-article","created":{"date-parts":[[2021,11,17]],"date-time":"2021-11-17T09:16:11Z","timestamp":1637140571000},"page":"6940","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":48,"title":["The Compositional Aspects of Edible Flowers as an Emerging Horticultural Product"],"prefix":"10.3390","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7739-623X","authenticated-orcid":false,"suffix":"Jr.","given":"Eleomar de O.","family":"Pires","sequence":"first","affiliation":[{"name":"Centro de Investiga\u00e7\u00e3o de Montanha (CIMO), Instituto Polit\u00e9cnico de Bragan\u00e7a, Campus de Santa Apol\u00f3nia, 5300-253 Bragan\u00e7a, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3509-3190","authenticated-orcid":false,"given":"Francesco","family":"Di Gioia","sequence":"additional","affiliation":[{"name":"Department of Plant Science, The Pennsylvania State University, University Park, PA 16802, USA"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1002-8651","authenticated-orcid":false,"given":"Youssef","family":"Rouphael","sequence":"additional","affiliation":[{"name":"Department of Agricultural Sciences, University of Naples Federico II, Via Universita 100, 80055 Portici, Italy"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4910-4882","authenticated-orcid":false,"given":"Isabel C. F. R.","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Centro de Investiga\u00e7\u00e3o de Montanha (CIMO), Instituto Polit\u00e9cnico de Bragan\u00e7a, Campus de Santa Apol\u00f3nia, 5300-253 Bragan\u00e7a, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5769-8484","authenticated-orcid":false,"given":"Cristina","family":"Caleja","sequence":"additional","affiliation":[{"name":"Centro de Investiga\u00e7\u00e3o de Montanha (CIMO), Instituto Polit\u00e9cnico de Bragan\u00e7a, Campus de Santa Apol\u00f3nia, 5300-253 Bragan\u00e7a, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9050-5189","authenticated-orcid":false,"given":"Lillian","family":"Barros","sequence":"additional","affiliation":[{"name":"Centro de Investiga\u00e7\u00e3o de Montanha (CIMO), Instituto Polit\u00e9cnico de Bragan\u00e7a, Campus de Santa Apol\u00f3nia, 5300-253 Bragan\u00e7a, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0324-7960","authenticated-orcid":false,"given":"Spyridon A.","family":"Petropoulos","sequence":"additional","affiliation":[{"name":"Department of Agriculture Crop Production and Rural Environment, University of Thessaly, Fytokou Street, N. 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The Mediterranean Diet: An Evidence-Based Approach, Academic Press."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.foodqual.2016.10.001","article-title":"Factors influencing consumers\u2019 attitudes towards the consumption of edible flowers","volume":"56","author":"Chen","year":"2017","journal-title":"Food Qual. Prefer."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.tifs.2019.02.015","article-title":"Edible flowers as functional food: A review on artichoke (Cynara cardunculus L.)","volume":"86","author":"Gostin","year":"2019","journal-title":"Trends Food Sci. Technol."},{"key":"ref_6","first-page":"197","article-title":"Nutritional content, functional properties and conservation of edible flowers. Review","volume":"63","year":"2013","journal-title":"Arch. Latinoam. Nutr."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.jfca.2017.03.017","article-title":"Edible flowers: A review of the nutritional, antioxidant, antimicrobial properties and effects on human health","volume":"60","author":"Fernandes","year":"2017","journal-title":"J. Food Compos. Anal."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1177\/1559827619895149","article-title":"La Culinary Medicine and Nature: Foods That Work Together","volume":"14","author":"Puma","year":"2020","journal-title":"Am. J. Lifestyle Med."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"104375","DOI":"10.1016\/j.jff.2021.104375","article-title":"Phytochemicals from edible flowers: Opening a new arena for healthy lifestyle","volume":"78","author":"Kumari","year":"2021","journal-title":"J. Funct. Foods"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"8496","DOI":"10.1021\/jf902103b","article-title":"Flavonoid composition and antioxidant activity of tree peony (Paeonia section moutan) yellow flowers","volume":"57","author":"Chonghui","year":"2009","journal-title":"J. Agric. Food Chem."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"3520","DOI":"10.1002\/jsfa.6291","article-title":"Preliminary sensory evaluation of edible flowers from wild Allium species","volume":"93","author":"Manco","year":"2013","journal-title":"J. Sci. Food Agric."},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Prabawati, N.B., Oktavirina, V., Palma, M., and Setyaningsih, W. (2021). Edible flowers: Antioxidant compounds and their functional properties. Horticulturae, 7.","DOI":"10.3390\/horticulturae7040066"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1111\/1750-3841.12404","article-title":"Phenolic Compounds and Antioxidant Capacities of 10 Common Edible Flowers from China","volume":"79","author":"Xiong","year":"2014","journal-title":"J. Food Sci."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.fct.2018.02.031","article-title":"Halophytic herbs of the Mediterranean basin: An alternative approach to health","volume":"114","author":"Petropoulos","year":"2018","journal-title":"Food Chem. Toxicol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fpls.2020.569499","article-title":"The Biodiversity of Edible Flowers: Discovering New Tastes and New Health Benefits","volume":"11","author":"Benvenuti","year":"2021","journal-title":"Front. Plant. Sci."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.fct.2018.07.007","article-title":"Are wild and cultivated flowers served in restaurants or sold by local producers in Denmark safe for the consumer?","volume":"120","author":"Egebjerg","year":"2018","journal-title":"Food Chem. Toxicol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1016\/j.foodres.2017.11.014","article-title":"Edible flowers as sources of phenolic compounds with bioactive potential","volume":"105","author":"Pires","year":"2018","journal-title":"Food Res. Int."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"108868","DOI":"10.1016\/j.foodres.2019.108868","article-title":"Edible flowers: Bioactive profile and its potential to be used in food development","volume":"129","author":"Takahashi","year":"2020","journal-title":"Food Res. Int."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.jpba.2019.05.007","article-title":"A systematic investigation on free phenolic acids and flavonoids profiles of commonly consumed edible flowers in China","volume":"172","author":"Zheng","year":"2019","journal-title":"J. Pharm. Biomed. Anal."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.tifs.2011.04.006","article-title":"Fresh edible flowers of ornamental plants-A new source of nutraceutical foods","volume":"22","author":"Mlcek","year":"2011","journal-title":"Trends Food Sci. Technol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"127940","DOI":"10.1016\/j.foodchem.2020.127940","article-title":"An update on the health benefits promoted by edible flowers and involved mechanisms","volume":"340","author":"Zheng","year":"2021","journal-title":"Food Chem."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"101249","DOI":"10.1016\/j.fbio.2021.101249","article-title":"Effect of edible rose (Rosa rugosa cv. Plena) flower extract addition on the physicochemical, rheological, functional and sensory properties of set-type yogurt","volume":"43","author":"Qiu","year":"2021","journal-title":"Food Biosci."},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Escher, G.B., Borges, L.D.C.C., Santos, J.S., Cruz, T.M., Marques, M.B., Do Carmo, M.A.V., Azevedo, L., Furtado, M.M., Sant\u2019ana, A.S., and Wen, M. (2019). From the field to the pot: Phytochemical and functional analyses of calendula officinalis l. flower for incorporation in an organic yogurt. Antioxidants, 8.","DOI":"10.3390\/antiox8110559"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/j.lwt.2018.08.013","article-title":"Incorporation of natural colorants obtained from edible flowers in yogurts","volume":"97","author":"Pires","year":"2018","journal-title":"LWT\u2014Food Sci. Technol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"2062","DOI":"10.1007\/s11947-019-02368-x","article-title":"Influence of Novel Infrared Freeze Drying of Rose Flavored Yogurt Melts on Their Physicochemical Properties, Bioactive Compounds and Energy Consumption","volume":"12","author":"Hnin","year":"2019","journal-title":"Food Bioprocess. Technol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.lwt.2018.02.009","article-title":"Gomphrena globosa L. as a novel source of food-grade betacyanins: Incorporation in ice-cream and comparison with beet-root extracts and commercial betalains","volume":"92","author":"Roriz","year":"2018","journal-title":"LWT"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/jfpp.14687","article-title":"Male date palm flower powder: Effect of incorporation on physico-chemical, textural, and sensory quality of biscuits","volume":"44","author":"Karra","year":"2020","journal-title":"J. Food Process. Preserv."},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Pires, D.O.E., Pereira, E., Carocho, M., Pereira, C., Dias, M.I., Calhelha, R.C., \u0106iri\u0107, A., Sokovi\u0107, M., Garcia, C.C., and Ferreira, I.C.F.R. (2021). Study on the potential application of Impatiens balsamina L. Flowers extract as a natural colouring ingredient in a pastry product. Int. J. Environ. Res. Public Health, 18.","DOI":"10.3390\/ijerph18179062"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/j.foodchem.2018.09.099","article-title":"Stability of a cyanidin-3-O-glucoside extract obtained from Arbutus unedo L. and incorporation into wafers for colouring purposes","volume":"275","author":"Caleja","year":"2019","journal-title":"Food Chem."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"S130","DOI":"10.1080\/10408398.2015.1078276","article-title":"Phytochemical Content, Health Benefits, and Toxicology of Common Edible Flowers: A Review (2000\u20132015)","volume":"56","author":"Lu","year":"2016","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.tifs.2019.09.020","article-title":"Edible flowers: Emerging components in the diet","volume":"93","author":"Pires","year":"2019","journal-title":"Trends Food Sci. Technol."},{"key":"ref_32","doi-asserted-by":"crossref","unstructured":"Fernandes, L., Ramalhosa, E., Pereira, J.A., Saraiva, J.A., and Casal, S. (2018). The unexplored potential of edible flowers lipids. Agric., 8.","DOI":"10.3390\/agriculture8100146"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"2512","DOI":"10.1111\/j.1365-2621.2009.02077.x","article-title":"Polyphenols: Food sources, properties and applications\u2014A review","volume":"44","year":"2009","journal-title":"Int. J. Food Sci. Technol."},{"key":"ref_34","doi-asserted-by":"crossref","unstructured":"Tom\u00e1s-Barber\u00e1n, F.A., Gonz\u00e1lez-Sarr\u00edas, A., and Garc\u00eda-Villalba, R. (2020). Structural Diversity of Polyphenols and Distribution in Foods. Dietary Polyphenols: Their Metabolism and Health Effects, John Wiley & Sons, Inc.. Wiley Online Books.","DOI":"10.1002\/9781119563754"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/j.indcrop.2017.10.051","article-title":"Antioxidant capacities and total phenolic contents of 30 flowers","volume":"111","author":"Chen","year":"2018","journal-title":"Ind. Crops Prod."},{"key":"ref_36","first-page":"805","article-title":"Nutritional composition and antioxidant capacity in edible flowers: Characterisation of phenolic compounds by HPLC-DAD-ESI\/MSn","volume":"16","author":"Periago","year":"2015","journal-title":"Int. J. Mol. Sci."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.tifs.2021.08.004","article-title":"Effect of withering process on the evolution of phenolic acids in winegrapes: A systematic review","volume":"116","author":"Scalzini","year":"2021","journal-title":"Trends Food Sci. Technol."},{"key":"ref_38","doi-asserted-by":"crossref","unstructured":"Saleem, H., Htar, T.T., Naidu, R., Anwar, S., Zengin, G., Locatelli, M., and Ahemad, N. (2020). HPLC\u2013PDA polyphenolic quantification, UHPLC\u2013MS secondary metabolite composition, and in vitro enzyme inhibition potential of Bougainvillea glabra. Plants, 9.","DOI":"10.3390\/plants9030388"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fphar.2020.01068","article-title":"Traditional Uses, Chemical Constituents, Biological Properties, Clinical Settings, and Toxicities of Abelmoschus manihot L.: A Comprehensive Review","volume":"11","author":"Luan","year":"2020","journal-title":"Front. Pharmacol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.sajb.2018.04.006","article-title":"A comparative study of the in vitro enzyme inhibitory and antioxidant activities of Butea monosperma (Lam.) Taub. and Sesbania grandiflora (L.) Poiret from Pakistan: New sources of natural products for public health problems","volume":"120","author":"Baessa","year":"2019","journal-title":"S. Afr. J. Bot."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"102081","DOI":"10.1016\/j.bcab.2021.102081","article-title":"Antioxidant activities of hydro-methanolic extracts of Sri Lankan edible flowers","volume":"35","author":"Janarny","year":"2021","journal-title":"Biocatal. Agric. Biotechnol."},{"key":"ref_42","first-page":"2605","article-title":"Chemical investigation of flavonoid, phenolic acids composition and antioxidant activity of mexican marigold (Tagetes erecta L.) flowers","volume":"63","author":"Youssef","year":"2020","journal-title":"Egypt. J. Chem."},{"key":"ref_43","doi-asserted-by":"crossref","unstructured":"Nascimento, L.B.D.S., Gori, A., Raffaelli, A., Ferrini, F., and Brunetti, C. (2021). Phenolic compounds from leaves and flowers of Hibiscus roseus: Potential skin cosmetic applications of an under-investigated species. Plants, 10.","DOI":"10.3390\/plants10030522"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"27","DOI":"10.2478\/fhort-2021-0004","article-title":"Exploring wild edible flowers as a source of bioactive compounds: New perspectives in horticulture","volume":"33","author":"Demasi","year":"2021","journal-title":"Folia Hortic."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"354","DOI":"10.3746\/jkfn.2021.50.4.354","article-title":"Phenolic compounds and antioxidant activities of 21 different rose flower cultivar","volume":"50","author":"Jo","year":"2021","journal-title":"J. Korean Soc. Food Sci. Nutr."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/jfpp.14982","article-title":"Effects of drying methods on phenolic components in different parts of Chrysanthemum morifolium flower","volume":"44","author":"Lu","year":"2020","journal-title":"J. Food Process. Preserv."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"108899","DOI":"10.1016\/j.foodres.2019.108899","article-title":"Phytochemicals screening, antioxidant capacity and chemometric characterization of four edible flowers from Brazil","volume":"130","author":"Barros","year":"2020","journal-title":"Food Res. Int."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"100492","DOI":"10.1016\/j.scp.2021.100492","article-title":"Ultrasound-assisted extraction of antioxidant phenolic compounds from Lavandula angustifolia flowers using natural deep eutectic solvents: An experimental design approach","volume":"22","author":"Alasalvar","year":"2021","journal-title":"Sustain. Chem. Pharm."},{"key":"ref_49","doi-asserted-by":"crossref","unstructured":"Krzymi\u0144ska, A., G\u0105secka, M., and Magdziak, Z. (2020). Content of phenolic compounds and organic acids in the flowers of selected Tulipa gesneriana cultivars. Molecules, 25.","DOI":"10.3390\/molecules25235627"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"e47","DOI":"10.1017\/jns.2016.41","article-title":"Flavonoids: An overview","volume":"5","author":"Panche","year":"2016","journal-title":"J. Nutr. Sci."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/j.aspen.2021.06.004","article-title":"Metabolomics reveals abundant flavonoids in edible insect Antheraea pernyi","volume":"24","author":"Fu","year":"2021","journal-title":"J. Asia. Pac. Entomol."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"103335","DOI":"10.1016\/j.jfca.2019.103335","article-title":"Comparative metabolomics reveals differences in flavonoid metabolites among different coloured buckwheat flowers","volume":"85","author":"Li","year":"2020","journal-title":"J. Food Compos. Anal."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.jconrel.2019.01.029","article-title":"Recent advances in topical delivery of flavonoids: A review","volume":"296","author":"Nagula","year":"2019","journal-title":"J. Control. Release"},{"key":"ref_54","doi-asserted-by":"crossref","unstructured":"Pensamiento-Ni\u00f1o, C.A., Campos-Montiel, R.G., A\u00f1orve-Morga, J., Ram\u00edrez-Moreno, E., Ascacio-Vald\u00e9s, J.A., and Hern\u00e1ndez-Fuentes, A.D. (2021). Nutritional Characterization of the Functional and Antioxidant Activity of Cactus Flowers from Hidalgo, Mexico. Appl. Sci., 11.","DOI":"10.3390\/app11135965"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"100235","DOI":"10.1016\/j.ijgfs.2020.100235","article-title":"Mexican edible flowers: Cultural background, traditional culinary uses, and potential health benefits","volume":"21","author":"Ozuna","year":"2020","journal-title":"Int. J. Gastron. Food Sci."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"101","DOI":"10.3109\/13880209.2010.497815","article-title":"The genus Artemisia: A comprehensive review","volume":"49","author":"Bora","year":"2011","journal-title":"Pharm. Biol."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1515\/opag-2020-0087","article-title":"Evaluation of phenolic compounds and antioxidant activity in some edible flowers","volume":"5","author":"Correia","year":"2020","journal-title":"Open Agric."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.jff.2015.05.028","article-title":"Total phenolic, flavonoid and antioxidant activity of 23 edible flowers subjected to in vitro digestion","volume":"17","author":"Chen","year":"2015","journal-title":"J. Funct. Foods"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"2467","DOI":"10.1021\/acs.jafc.5b03092","article-title":"Edible Flowers: A Rich Source of Phytochemicals with Antioxidant and Hypoglycemic Properties","volume":"64","author":"Loizzo","year":"2016","journal-title":"J. Agric. Food Chem."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1080\/19476337.2013.801037","article-title":"Flavonoid composition and antioxidant capacity of the edible flowers of Agave durangensis (Agavaceae)","volume":"12","year":"2014","journal-title":"CYTA\u2014J. Food"},{"key":"ref_61","doi-asserted-by":"crossref","unstructured":"Vidana Gamage, G.C., Lim, Y.Y., and Choo, W.S. (2021). Sources and relative stabilities of acylated and nonacylated anthocyanins in beverage systems. J. Food Sci. Technol.","DOI":"10.1007\/s13197-021-05054-z"},{"key":"ref_62","doi-asserted-by":"crossref","unstructured":"Mekapogu, M., Vasamsetti, B.M.K., Kwon, O.K., Ahn, M.S., Lim, S.H., and Jung, J.A. (2020). Anthocyanins in floral colors: Biosynthesis and regulation in chrysanthemum flowers. Int. J. Mol. Sci., 21.","DOI":"10.3390\/ijms21186537"},{"key":"ref_63","doi-asserted-by":"crossref","unstructured":"Karaaslan-Ayhan, N., and Yaman, M. (2021). Determination of anthocyanins and anthocyanidins in the wild grape (Vitis sylvestris Gmelin) by high-performance liquid chromatography-diode array detection (HPLC-DAD). Instrum. Sci. Technol., 1\u201312.","DOI":"10.1080\/10739149.2021.1954532"},{"key":"ref_64","doi-asserted-by":"crossref","unstructured":"Di Gioia, F., Tzortzakis, N., Rouphael, Y., Kyriacou, M.C., Sampaio, S.L., Ferreira, I.C.F.R., and Petropoulos, S.A. (2020). Grown to be blue\u2014antioxidant properties and health effects of colored vegetables. Part II: Leafy, fruit, and other vegetables. Antioxidants, 9.","DOI":"10.3390\/antiox9020097"},{"key":"ref_65","doi-asserted-by":"crossref","unstructured":"Mannino, G., Gentile, C., Ertani, A., Serio, G., and Bertea, C.M. (2021). Anthocyanins: Biosynthesis, distribution, ecological role, and use of biostimulants to increase their content in plant foods\u2014A review. Agriculture, 11.","DOI":"10.3390\/agriculture11030212"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"128526","DOI":"10.1016\/j.foodchem.2020.128526","article-title":"Anthocyanin-rich extracts from purple and red potatoes as natural colourants: Bioactive properties, application in a soft drink formulation and sensory analysis","volume":"342","author":"Sampaio","year":"2021","journal-title":"Food Chem."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"128853","DOI":"10.1016\/j.foodchem.2020.128853","article-title":"Potato biodiversity: A linear discriminant analysis on the nutritional and physicochemical composition of fifty genotypes","volume":"345","author":"Sampaio","year":"2021","journal-title":"Food Chem."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.tifs.2020.07.015","article-title":"Potato peels as sources of functional compounds for the food industry: A review","volume":"103","author":"Sampaio","year":"2020","journal-title":"Trends Food Sci. Technol."},{"key":"ref_69","doi-asserted-by":"crossref","unstructured":"Petropoulos, S.A., Sampaio, S.L., Di Gioia, F., Tzortzakis, N., Rouphael, Y., Kyriacou, M.C., and Ferreira, I. (2019). Grown to be blue\u2014antioxidant properties and health effects of colored vegetables. Part I: Root vegetables. Antioxidants, 8.","DOI":"10.3390\/antiox8120617"},{"key":"ref_70","doi-asserted-by":"crossref","unstructured":"Tena, N., Mart\u00edn, J., and Asuero, A.G. (2020). State of the art of anthocyanins: Antioxidant activity, sources, bioavailability, and therapeutic effect in human health. Antioxidants, 9.","DOI":"10.3390\/antiox9050451"},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.scienta.2015.12.052","article-title":"Antioxidant power, anthocyanin content and organoleptic performance of edible flowers","volume":"199","author":"Benvenuti","year":"2016","journal-title":"Sci. Hortic."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.1021\/jf503366c","article-title":"Identification of Phenolic Compounds in Petals of Nasturtium Flowers (Tropaeolum majus) by High-Performance Liquid Chromatography Coupled to Mass Spectrometry and Determination of Oxygen Radical Absorbance Capacity (ORAC)","volume":"63","author":"Manns","year":"2015","journal-title":"J. Agric. Food Chem."},{"key":"ref_73","doi-asserted-by":"crossref","unstructured":"Hallmann, E. (2020). Quantitative and qualitative identification of bioactive compounds in edible flowers of black and bristly locust and their antioxidant activity. Biomolecules, 10.","DOI":"10.3390\/biom10121603"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"460472","DOI":"10.1016\/j.chroma.2019.460472","article-title":"A comprehensive study of pomegranate flowers polyphenols and metabolites in rat biological samples by high-performance liquid chromatography quadrupole time-of-flight mass spectrometry","volume":"1604","author":"Yisimayili","year":"2019","journal-title":"J. Chromatogr. A"},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/s11130-020-00813-3","article-title":"Determination of Anthocyanins and Antioxidants in \u2018Titanbicus\u2019 Edible Flowers In Vitro and In Vivo","volume":"75","author":"Chensom","year":"2020","journal-title":"Plant. Foods Hum. Nutr."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s42452-020-04092-0","article-title":"Physicochemical, nutritional, bioactive compounds and fatty acid profiling of Pumpkin flower (Cucurbita maxima), as a potential functional food","volume":"3","author":"Ghosh","year":"2021","journal-title":"SN Appl. Sci."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/j.fct.2013.05.021","article-title":"Cytotoxic and bioactive properties of different color tulip flowers and degradation kinetic of tulip flower anthocyanins","volume":"58","author":"Sagdic","year":"2013","journal-title":"Food Chem. Toxicol."},{"key":"ref_78","doi-asserted-by":"crossref","unstructured":"Pires, D.O.E., Pereira, E., Pereira, C., Dias, M.I., Calhelha, R.C., \u0106iri\u0107, A., Sokovi\u0107, M., Hassemer, G., Garcia, C.C., and Caleja, C. (2021). Chemical composition and bioactive characterisation of Impatiens walleriana. Molecules, 26.","DOI":"10.3390\/molecules26051347"},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"1988","DOI":"10.1080\/07373937.2019.1647437","article-title":"Influences of four pretreatments on anthocyanins content, color and flavor characteristics of hot-air dried rose flower","volume":"38","author":"Barani","year":"2020","journal-title":"Dry. Technol."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"6966","DOI":"10.1021\/jf502444u","article-title":"Effect of salt stress in the regulation of anthocyanins and color of Hibiscus flowers by digital image analysis","volume":"62","author":"Trivellini","year":"2014","journal-title":"J. Agric. Food Chem."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"105315","DOI":"10.1016\/j.bioorg.2021.105315","article-title":"Synthesis of chalcones derived from 1-naphthylacetophenone and evaluation of their cytotoxic and apoptotic effects in acute leukemia cell lines","volume":"116","author":"Jacques","year":"2021","journal-title":"Bioorg. Chem."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.21577\/1984-6835.20180099","article-title":"Chalcones pharmacological potential: A brief review","volume":"10","author":"Ferreira","year":"2018","journal-title":"Rev. Virtual Quim."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/s11101-014-9387-8","article-title":"Naturally occurring chalcones and their biological activities","volume":"15","author":"Rozmer","year":"2016","journal-title":"Phytochem. Rev."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"450","DOI":"10.2503\/hortj.UTD-305","article-title":"Identification of Chalcones and their Contribution to Yellow Coloration in Dahlia (Dahlia variabilis) Ray Florets","volume":"90","author":"Ohno","year":"2021","journal-title":"Hortic. J."},{"key":"ref_85","doi-asserted-by":"crossref","unstructured":"Onozaki, T., and Yagi, M. (2020). Flower Pigments Responsible for Cyanic, Yellow, and Cream-White Coloration in Carnation. The Carnation Genome, Springer.","DOI":"10.1007\/978-981-15-8261-5"},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.molliq.2018.04.135","article-title":"Efficient determination of three flavonoids in Malus pumila flowers by ionic liquid-HPLC","volume":"263","author":"Li","year":"2018","journal-title":"J. Mol. Liq."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.bioorg.2019.01.003","article-title":"Lanceoleins A\u2013G, hydroxychalcones, from the flowers of Coreopsis lanceolata and their chemopreventive effects against human colon cancer cells","volume":"85","author":"Kim","year":"2019","journal-title":"Bioorg. Chem."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.chroma.2015.10.037","article-title":"Comparison of antioxidant activities of different parts from snow chrysanthemum (Coreopsis tinctoria Nutt.) and identification of their natural antioxidants using high performance liquid chromatography coupled with diode array detection and mass sp.","volume":"1428","author":"Chen","year":"2016","journal-title":"J. Chromatogr. A"},{"key":"ref_89","unstructured":"Tom\u00e1s-Barber\u00e1n, F.A., and Gil, M.I. (2008). Overview of health-promoting compounds in fruit and vegetables. Woodhead Publishing Series in Food Science, Technology and Nutrition, Woodhead Publishing."},{"key":"ref_90","unstructured":"Grumezescu, A.M., and Holban, A.M. (2019). Phenolic Compounds as Functional Ingredients in Beverages. Value-Added Ingredients and Enrichments of Beverages, Academic Press."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.tifs.2020.09.023","article-title":"Edible flowers as functional raw materials: A review on anti-aging properties","volume":"106","author":"Chen","year":"2020","journal-title":"Trends Food Sci. Technol."},{"key":"ref_92","first-page":"101","article-title":"Antioxidant capacity, nutritional and functional composition of edible Dahlia flowers","volume":"20","year":"2014","journal-title":"Rev. Chapingo Ser. Hortic."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.3390\/molecules17021203","article-title":"Phenolic compounds characterization and biological activities of Citrus aurantium bloom","volume":"17","author":"Karimi","year":"2012","journal-title":"Molecules"},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.foodres.2019.04.046","article-title":"Classification of edible chrysanthemums based on phenolic profiles and mechanisms underlying the protective effects of characteristic phenolics on oxidatively damaged erythrocyte","volume":"123","author":"Peng","year":"2019","journal-title":"Food Res. Int."},{"key":"ref_95","doi-asserted-by":"crossref","unstructured":"Jiang, N., Doseff, A.I., and Grotewold, E. (2016). Flavones: From biosynthesis to health benefits. Plants, 5.","DOI":"10.3390\/plants5020027"},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1080\/10408398.2020.1752142","article-title":"Degradation and regulation of edible flower pigments under thermal processing: A review","volume":"61","author":"Xu","year":"2021","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1111\/jphp.13016","article-title":"Total flavones of Rhododendron simsii Planch flower protect isolated rat heart from ischaemia-reperfusion injury and its mechanism of UTR-RhoA-ROCK pathway inhibition","volume":"70","author":"Sun","year":"2018","journal-title":"J. Pharm. Pharmacol."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"129718","DOI":"10.1016\/j.snb.2021.129718","article-title":"Flavonol-based small-molecule fluorescent probes","volume":"336","author":"Qin","year":"2021","journal-title":"Sens. Actuators B Chem."},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"111253","DOI":"10.1016\/j.biopha.2021.111253","article-title":"Mechanistic new insights of flavonols on neurodegenerative diseases","volume":"137","author":"Tahir","year":"2021","journal-title":"Biomed. Pharmacother."},{"key":"ref_100","first-page":"1","article-title":"Detection and isolation of flavonoids from Calendula officinalis (F","volume":"25","author":"Hamad","year":"2016","journal-title":"Asteraceae) cultivated in Iraq."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.foodres.2011.06.016","article-title":"Potential health enhancing properties of edible flowers from Thailand","volume":"46","author":"Kaisoon","year":"2012","journal-title":"Food Res. Int."},{"key":"ref_102","unstructured":"Caballero, B., Finglas, P.M., and Toldr\u00e1, F. (2016). Phenolic Compounds: Occurrence, Classes, and Analysis, Academic Press."},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1021\/jf020870v","article-title":"Determination of tea polyphenols and caffeine in tea flowers (Camellia sinensis) and their hydroxyl radical scavenging and nitric oxide suppressing effects","volume":"51","author":"Lin","year":"2003","journal-title":"J. Agric. Food Chem."},{"key":"ref_104","doi-asserted-by":"crossref","unstructured":"Yang, R., Guan, Y., Wang, W., Chen, H., He, Z., and Jia, A.Q. (2018). Antioxidant capacity of phenolics in Camellia nitidissima Chi flowers and their identification by HPLC Triple TOF MS\/MS. PLoS ONE, 13.","DOI":"10.1371\/journal.pone.0195508"},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.1016\/j.foodchem.2012.06.056","article-title":"Antioxidant and \u03b1-glucosidase inhibitory phenolics isolated from highbush blueberry flowers","volume":"135","author":"Wan","year":"2012","journal-title":"Food Chem."},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"109046","DOI":"10.1016\/j.foodres.2020.109046","article-title":"Antioxidant activity and bioaccessibility of phenolic compounds in white, red, blue, purple, yellow and orange edible flowers through a simulated intestinal barrier","volume":"131","author":"Dantas","year":"2020","journal-title":"Food Res. Int."},{"key":"ref_107","first-page":"717","article-title":"Variation of phenolic compounds and antioxidant capacities in different organs of Lilium pumilum","volume":"13","author":"Liang","year":"2018","journal-title":"Nat. Prod. Commun."},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.jff.2013.10.022","article-title":"Total phenolic contents and antioxidant capacities of 51 edible and wild flowers","volume":"6","author":"Li","year":"2014","journal-title":"J. Funct. Foods"},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1016\/j.indcrop.2012.10.004","article-title":"Identification and quantification of flavonols, anthocyanins and lutein diesters in tepals of Crocus sativus by ultra performance liquid chromatography coupled to diode array and ion trap mass spectrometry detections","volume":"44","author":"Goupy","year":"2013","journal-title":"Ind. Crops Prod."},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.foodchem.2013.02.010","article-title":"Systematic qualitative and quantitative assessment of anthocyanins, flavones and flavonols in the petals of 108 lotus (Nelumbo nucifera) cultivars","volume":"139","author":"Deng","year":"2013","journal-title":"Food Chem."},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.foodchem.2014.04.097","article-title":"Comparative chemical and biochemical analysis of extracts of Hibiscus sabdariffa","volume":"164","author":"Sindi","year":"2014","journal-title":"Food Chem."},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"11090","DOI":"10.3390\/molecules200611090","article-title":"Anthocyanin and carotenoid contents in different cultivars of chrysanthemum (Dendranthema grandiflorum Ramat.) flower","volume":"20","author":"Park","year":"2015","journal-title":"Molecules"},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"4757","DOI":"10.1021\/jf0502000","article-title":"Antioxidant activity of the flavonoid hesperidin in chemical and biological systems","volume":"53","author":"Wilmsen","year":"2005","journal-title":"J. Agric. Food Chem."},{"key":"ref_114","first-page":"409","article-title":"Carotenoid composition of Brazilizn fruits and vegetables","volume":"744","author":"Kimura","year":"2007","journal-title":"Acta Hortic."},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/j.foodres.2018.10.043","article-title":"Marigold carotenoids: Much more than lutein esters","volume":"119","author":"Rodrigues","year":"2019","journal-title":"Food Res. Int."},{"key":"ref_116","doi-asserted-by":"crossref","unstructured":"Park, Y.J., Park, S.Y., Arasu, M.V., Al-Dhabi, N.A., Ahn, H.G., Kim, J.K., Park, S.U., and Iriti, M. (2017). Accumulation of carotenoids and metabolic profiling in different cultivars of Tagetes flowers. Molecules, 22.","DOI":"10.3390\/molecules22020313"},{"key":"ref_117","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.scienta.2013.06.018","article-title":"Qualitative and quantitative control of carotenoid accumulation in flower petals","volume":"163","author":"Ohmiya","year":"2013","journal-title":"Sci. Hortic."},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.abb.2010.07.028","article-title":"The regulation of carotenoid pigmentation in flowers","volume":"504","author":"Zhu","year":"2010","journal-title":"Arch. Biochem. Biophys."},{"key":"ref_119","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.abb.2018.06.001","article-title":"Carotenoids in human nutrition and health","volume":"652","author":"Eggersdorfer","year":"2018","journal-title":"Arch. Biochem. Biophys."},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"644","DOI":"10.21273\/HORTTECH.11.4.644","article-title":"Consumer ratings of edible flower quality, mix, and color","volume":"11","author":"Kelley","year":"2001","journal-title":"HortTechnology"},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"801","DOI":"10.21273\/HORTSCI.36.4.801","article-title":"Consumer preference for edible-flower color, container size, and price","volume":"36","author":"Kelley","year":"2001","journal-title":"HortScience"},{"key":"ref_122","doi-asserted-by":"crossref","unstructured":"Jacob-Lopes, E., Queiroz, M.I., and Zepka Queiroz, L. (2020). Nutraceutical and Pharmaceutical Applications of Carotenoids. Pigments from Microalgae Handbook, Springer Nature Switzerland AG.","DOI":"10.1007\/978-3-030-50971-2"},{"key":"ref_123","unstructured":"Galanakis, C.M. (2020). Overview of carotenoids and beneficial effects on human health. Carotenoids: Properties, Processing and Applications, Academic Press."},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.fct.2018.07.060","article-title":"Antioxidant and pro-oxidant activities of carotenoids and their oxidation products","volume":"120","author":"Ribeiro","year":"2018","journal-title":"Food Chem. Toxicol."},{"key":"ref_125","doi-asserted-by":"crossref","unstructured":"Young, A.J., and Lowe, G.L. (2018). Carotenoids\u2014Antioxidant properties. Antioxidants, 7.","DOI":"10.3390\/antiox7020028"},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"171","DOI":"10.3746\/pnf.2019.24.2.171","article-title":"Primary screening of antioxidant activity, total polyphenol content, carotenoid content, and nutritional composition of 13 edible flowers from Japan","volume":"24","author":"Chensom","year":"2019","journal-title":"Prev. Nutr. Food Sci."},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/rcm.9142","article-title":"Distinguishing between isomeric neoxanthin and violaxanthin esters in yellow flower petals using liquid chromatography\/photodiode array atmospheric pressure chemical ionization mass spectrometry and tandem mass spectrometry","volume":"35","author":"Watanabe","year":"2021","journal-title":"Rapid Commun. Mass Spectrom."},{"key":"ref_128","doi-asserted-by":"crossref","unstructured":"Mart\u00ednez-S\u00e1nchez, A., L\u00f3pez-Ca\u00f1avate, M.E., Guirao-Mart\u00ednez, J., Roca, M.J., and Aguayo, E. (2020). Aloe vera flowers, a byproduct with great potential and wide application, depending on maturity stage. Foods, 9.","DOI":"10.3390\/foods9111542"},{"key":"ref_129","first-page":"107","article-title":"Analysis of carotenoids compounds and their biosynthesis pathways in flowers of three Dendrobium species","volume":"32","author":"Huang","year":"2019","journal-title":"For. Res."},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"111981","DOI":"10.1016\/j.indcrop.2019.111981","article-title":"Transcriptomics and targeted metabolomics profilings for elucidation of pigmentation in Lonicera japonica flowers at different developmental stages","volume":"145","author":"Xue","year":"2020","journal-title":"Ind. Crops Prod."},{"key":"ref_131","doi-asserted-by":"crossref","unstructured":"Amengual, J. (2019). Bioactive properties of carotenoids in human health. Nutrients, 11.","DOI":"10.3390\/nu11102388"},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"3164312","DOI":"10.1155\/2016\/3164312","article-title":"Carotenoids functionality, sources, and processing by supercritical technology: A review","volume":"2016","author":"Mezzomo","year":"2016","journal-title":"J. Chem."},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1007\/s10068-018-0326-0","article-title":"Effect of alginate coating on the physico-chemical and microbial quality of pansies (Viola \u00d7 wittrockiana) during storage","volume":"27","author":"Fernandes","year":"2018","journal-title":"Food Sci. Biotechnol."},{"key":"ref_134","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1007\/s13580-020-00249-3","article-title":"Floral pigment-scent associations in eight cut rose cultivars with various petal colors","volume":"61","author":"Yeon","year":"2020","journal-title":"Hortic. Environ. Biotechnol."},{"key":"ref_135","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.tifs.2019.05.008","article-title":"Edible flowers with the common name \u201cmarigold\u201d: Their therapeutic values and processing","volume":"89","author":"Chitrakar","year":"2019","journal-title":"Trends Food Sci. Technol."},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"117104","DOI":"10.1016\/j.lfs.2019.117104","article-title":"Xanthophyll: Health benefits and therapeutic insights","volume":"240","author":"Aziz","year":"2020","journal-title":"Life Sci."},{"key":"ref_137","doi-asserted-by":"crossref","unstructured":"Combs, G.F.B.J. (2012). Chapter 18-Quasi-Vitamins. The Vitamins, Academic Press.","DOI":"10.1016\/B978-0-12-381980-2.00018-9"},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1111\/tpj.12570","article-title":"Identification of the carotenoid modifying gene PALE YELLOW PETAL 1 as an essential factor in xanthophyll esterification and yellow flower pigmentation in tomato (Solanum lycopersicum)","volume":"79","author":"Ariizumi","year":"2014","journal-title":"Plant. J."},{"key":"ref_139","first-page":"310","article-title":"Xanthophyll esters in fruits and vegetables","volume":"42","author":"Bunea","year":"2014","journal-title":"Not. Bot. Horti Agrobot."},{"key":"ref_140","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-020-58313-y","article-title":"Heterologous expression of xanthophyll esterase genes affects carotenoid accumulation in petunia corollas","volume":"10","author":"Kishimoto","year":"2020","journal-title":"Sci. Rep."},{"key":"ref_141","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1080\/00986445.2019.1630390","article-title":"Chromatographic modeling of free lutein derived from marigold flowers","volume":"207","author":"Clowutimon","year":"2020","journal-title":"Chem. Eng. Commun."},{"key":"ref_142","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.jksus.2012.12.003","article-title":"Antioxidant and antibacterial activities of hibiscus (Hibiscus rosa-sinensis L.) and Cassia (Senna bicapsularis L.) flower extracts","volume":"25","author":"Mak","year":"2013","journal-title":"J. King Saud Univ.\u2014Sci."},{"key":"ref_143","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/S0167-4781(03)00017-4","article-title":"cDNAs for the synthesis of cyclic carotenoids in petals of Gentiana lutea and their regulation during flower development","volume":"1625","author":"Zhu","year":"2003","journal-title":"Biochim. Biophys. Acta\u2014Gene Struct. Expr."},{"key":"ref_144","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1111\/j.1439-0523.2009.01656.x","article-title":"Carotenoid composition and changes in expression of carotenoid biosynthetic genes in tepals of Asiatic hybrid lily","volume":"129","author":"Yamagishi","year":"2010","journal-title":"Plant. Breed."},{"key":"ref_145","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.foodchem.2018.01.102","article-title":"Chemical composition of the edible flowers, pansy (Viola wittrockiana) and snapdragon (Antirrhinum majus) as new sources of bioactive compounds","volume":"252","author":"Periago","year":"2018","journal-title":"Food Chem."},{"key":"ref_146","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.foodres.2012.02.008","article-title":"Identification of previously unreported pigments among carotenoids and anthocyanins in floral petals of Delonix regia (Hook.) Raf.1. Veigas, J.M.; Divya, P.; Neelwarne, B. Identification of previously unreported pigments among carotenoids and anthocyanins","volume":"47","author":"Veigas","year":"2012","journal-title":"Food Res. Int."},{"key":"ref_147","doi-asserted-by":"crossref","first-page":"4343","DOI":"10.1007\/s11694-021-01015-4","article-title":"Comparative study on color coordinates, phenolics, flavonoids, carotenoids, and antioxidant potential of marigold (Tagetes sp.) with diverse colored petals","volume":"15","author":"Manivannan","year":"2021","journal-title":"J. Food Meas. Charact."},{"key":"ref_148","doi-asserted-by":"crossref","first-page":"5962","DOI":"10.1021\/jf000956t","article-title":"Analysis and stability of carotenoids in the flowers of daylily (Hemerocallis disticha) as affected by various treatments","volume":"48","author":"Tai","year":"2000","journal-title":"J. Agric. Food Chem."},{"key":"ref_149","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1093\/jxb\/erp335","article-title":"Carotenoid composition and carotenogenic gene expression during Ipomoea petal development","volume":"61","author":"Yamamizo","year":"2010","journal-title":"J. Exp. Bot."},{"key":"ref_150","doi-asserted-by":"crossref","unstructured":"Li, X., Lu, M., Tang, D., and Shi, Y. (2015). Composition of carotenoids and flavonoids in Narcissus cultivars and their relationship with flower color. PLoS ONE, 10.","DOI":"10.1371\/journal.pone.0142074"},{"key":"ref_151","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/j.foodres.2019.05.014","article-title":"Phytochemical characterization of Borago officinalis L. and Centaurea cyanus L. during flower development","volume":"123","author":"Fernandes","year":"2019","journal-title":"Food Res. Int."},{"key":"ref_152","doi-asserted-by":"crossref","first-page":"109070","DOI":"10.1016\/j.foodres.2020.109070","article-title":"Borage, camellia, centaurea and pansies: Nutritional, fatty acids, free sugars, vitamin E, carotenoids and organic acids characterization","volume":"132","author":"Fernandes","year":"2020","journal-title":"Food Res. Int."},{"key":"ref_153","first-page":"327","article-title":"Determination of Major Carotenoid Constituents in Petal Extracts of Eight Selected Flowering Plants in the North of Thailand","volume":"33","author":"Tinoi","year":"2006","journal-title":"Chiang Mai J. Sci."},{"key":"ref_154","first-page":"1","article-title":"Analysis of carotenoids in edible flowers of Dianthus chinensis processed by ionizing radiation","volume":"9","author":"Koike","year":"2021","journal-title":"Braz. J. Radiat. Sci."},{"key":"ref_155","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1111\/pbr.12043","article-title":"Carotenoid accumulations and carotenogenic gene expressions in the petals of Eustoma grandiflorum","volume":"132","author":"Liu","year":"2013","journal-title":"Plant. Breed."},{"key":"ref_156","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/j.jff.2012.05.002","article-title":"Changes in colour, antioxidant activities and carotenoids (lycopene, \u03b2-carotene, lutein) of marigold flower (Tagetes erecta L.) resulting from different drying processes","volume":"4","author":"Siriamornpun","year":"2012","journal-title":"J. Funct. Foods"},{"key":"ref_157","doi-asserted-by":"crossref","first-page":"S605","DOI":"10.1111\/j.1365-2621.2005.tb08336.x","article-title":"Flowers and leaves of Tropaeolum majus L. as rich sources of lutein","volume":"70","author":"Niizu","year":"2005","journal-title":"J. Food Sci."},{"key":"ref_158","doi-asserted-by":"crossref","first-page":"4171","DOI":"10.1021\/acs.jafc.8b01509","article-title":"Flavonols and Carotenoids in Yellow Petals of Rose Cultivar (Rosa \u2019Sun City\u2019): A Possible Rich Source of Bioactive Compounds","volume":"66","author":"Wan","year":"2018","journal-title":"J. Agric. Food Chem."},{"key":"ref_159","first-page":"299","article-title":"Alkaloid contents and antio-xidant effectiveness of extracts of the Orobanche aegyptiaca L. and Orobanche ramosa L. (Orobanchaceae)","volume":"7","author":"Salih","year":"2016","journal-title":"J. Plant. Prod."},{"key":"ref_160","doi-asserted-by":"crossref","first-page":"104723","DOI":"10.1016\/j.phrs.2020.104723","article-title":"Anti-diabetic potential of plant alkaloids: Revisiting current findings and future perspectives","volume":"155","author":"Rasouli","year":"2020","journal-title":"Pharmacol. Res."},{"key":"ref_161","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1039\/a809393h","article-title":"The biosynthesis of plant alkaloids and nitrogenous microbial metabolites","volume":"18","author":"Herbert","year":"2001","journal-title":"Nat. Prod. Rep."},{"key":"ref_162","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.phytol.2016.11.009","article-title":"Comparative HILIC\/ESI-QTOF-MS and HPTLC studies of pyrrolizidine alkaloids in flowers of Tussilago farfara and roots of Arnebia euchroma","volume":"20","author":"Wojtanowski","year":"2017","journal-title":"Phytochem. Lett."},{"key":"ref_163","doi-asserted-by":"crossref","first-page":"104729","DOI":"10.1016\/j.fitote.2020.104729","article-title":"Prenylated indole alkaloids and lignans from the flower buds of Tussilago farfara","volume":"146","author":"Song","year":"2020","journal-title":"Fitoterapia"},{"key":"ref_164","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.jksus.2014.02.005","article-title":"Structurally diverse alkaloids from Tecomella undulata G. Don flowers","volume":"26","author":"Laghari","year":"2014","journal-title":"J. King Saud Univ.\u2014Sci."},{"key":"ref_165","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.yebeh.2012.01.003","article-title":"Erysothrine, an alkaloid extracted from flowers of Erythrina mulungu Mart. ex Benth: Evaluating its anticonvulsant and anxiolytic potential","volume":"23","author":"Rosa","year":"2012","journal-title":"Epilepsy Behav."},{"key":"ref_166","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1016\/j.fitote.2010.06.017","article-title":"Two new amide alkaloids from the flower of Datura metel L.","volume":"81","author":"Yang","year":"2010","journal-title":"Fitoterapia"},{"key":"ref_167","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.phytol.2020.01.007","article-title":"Four new quinolizidine alkaloids from the flowers of Sophora viciifolia","volume":"36","author":"Gao","year":"2020","journal-title":"Phytochem. Lett."},{"key":"ref_168","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/j.fct.2018.06.007","article-title":"Indole alkaloids and anti-nociceptive mechanisms of Tabernaemontana divaricata (L.) R. Br. flower methanolic extract","volume":"118","author":"Misbah","year":"2018","journal-title":"Food Chem. Toxicol."},{"key":"ref_169","unstructured":"Gonz\u00e1lez, H.D., and Munoz, M.J.G. (2017). Microwave-Assisted Extraction of Betalains. Water Extraction of Bioactive Compounds. From Plants to Drug Development, Elsevier."},{"key":"ref_170","unstructured":"Carle, R., and Schweiggert, R.M. (2016). Betalains. Handbook on Natural Pigments in Food and Beverages. Industrial Applications for Improving Food Color, Woodhead Publishing."},{"key":"ref_171","doi-asserted-by":"crossref","unstructured":"Miguel, M.G. (2018). Betalains in some species of the Amaranthaceae family: A review. Antioxidants, 7.","DOI":"10.3390\/antiox7040053"},{"key":"ref_172","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1007\/s13197-019-04120-x","article-title":"Stabilization of betalains by encapsulation\u2014A review","volume":"57","year":"2020","journal-title":"J. Food Sci. Technol."},{"key":"ref_173","doi-asserted-by":"crossref","unstructured":"Sanches Silva, A., Nabavi, S.F., Saeedi, M., and Nabavi, S.M. (2020). Analysis of betalains (betacyanins and betaxanthins). Recent Advances in Natural Products Analysis, Elsevier.","DOI":"10.1016\/B978-0-12-816455-6.00027-5"},{"key":"ref_174","doi-asserted-by":"crossref","unstructured":"Sadowska-Bartosz, I., and Bartosz, G. (2021). Biological properties and applications of betalains. Molecules, 26.","DOI":"10.3390\/molecules26092520"},{"key":"ref_175","first-page":"104","article-title":"Studies on Extraction of Betalain Pigments by Different Solvents and Assessing Antioxidant Activity of Bougainvillea spectabilis and Celosia argentea Flowers","volume":"106","author":"Lavanya","year":"2019","journal-title":"Madras Agric. J."},{"key":"ref_176","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1007\/s00216-006-0897-0","article-title":"Characterisation of betalain patterns of differently coloured inflorescences from Gomphrena globosa L. and Bougainvillea sp. by HPLC-DAD-ESI-MSn","volume":"387","author":"Kugler","year":"2007","journal-title":"Anal. Bioanal. Chem."},{"key":"ref_177","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/S0031-9422(00)00129-1","article-title":"Betalains from Christmas cactus","volume":"54","author":"Kobayashi","year":"2000","journal-title":"Phytochemistry"},{"key":"ref_178","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.jlumin.2015.06.030","article-title":"Photophysical properties of betaxanthins: Vulgaxanthin I in aqueous and alcoholic solutions","volume":"167","author":"Wendel","year":"2015","journal-title":"J. Lumin."},{"key":"ref_179","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.tplants.2019.11.001","article-title":"Light Emission in Betalains: From Fluorescent Flowers to Biotechnological Applications","volume":"25","author":"Escribano","year":"2020","journal-title":"Trends Plant. Sci."},{"key":"ref_180","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/S0031-9422(02)00564-2","article-title":"Recent advances in betalain research","volume":"62","author":"Strack","year":"2003","journal-title":"Phytochemistry"},{"key":"ref_181","first-page":"292","article-title":"Betalains: From the colors of beetroots to the fluorescence of flowers","volume":"7","author":"Marcato","year":"2015","journal-title":"Rev. Virtual Quim."},{"key":"ref_182","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.jfca.2014.09.003","article-title":"Characterization of phenolics, betacyanins and antioxidant activities of the seed, leaf, sprout, flower and stalk extracts of three Amaranthus species","volume":"37","author":"Li","year":"2015","journal-title":"J. Food Compos. Anal."},{"key":"ref_183","doi-asserted-by":"crossref","first-page":"127178","DOI":"10.1016\/j.foodchem.2020.127178","article-title":"Betacyanins from Gomphrena globosa L. flowers: Incorporation in cookies as natural colouring agents","volume":"329","author":"Roriz","year":"2020","journal-title":"Food Chem."},{"key":"ref_184","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.foodchem.2017.02.073","article-title":"Floral parts of Gomphrena globosa L. as a novel alternative source of betacyanins: Optimization of the extraction using response surface methodology","volume":"229","author":"Roriz","year":"2017","journal-title":"Food Chem."},{"key":"ref_185","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.ijbiomac.2021.04.152","article-title":"Development of active and smart packaging films based on starch, polyvinyl alcohol and betacyanins from different plant sources","volume":"183","author":"Yao","year":"2021","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_186","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.chroma.2017.01.064","article-title":"Separation of betacyanins from purple flowers of Gomphrena globosa L. by ion-pair high-speed counter-current chromatography","volume":"1489","author":"Wybraniec","year":"2017","journal-title":"J. Chromatogr. A"},{"key":"ref_187","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.indcrop.2014.09.059","article-title":"Optimization of ultrasound-assisted extraction of natural pigments from Bougainvillea glabra flowers","volume":"63","author":"Maran","year":"2015","journal-title":"Ind. Crops Prod."},{"key":"ref_188","doi-asserted-by":"crossref","unstructured":"Roriz, C.L., Xavier, V., Heleno, S.A., Pinela, J., Dias, M.I., Calhelha, R.C., Morales, P., Ferreira, I.C.F.R., and Barros, L. (2021). Chemical and bioactive features of Amaranthus caudatus L. flowers and optimized ultrasound-assisted extraction of betalains. Foods, 10.","DOI":"10.3390\/foods10040779"},{"key":"ref_189","doi-asserted-by":"crossref","first-page":"72","DOI":"10.3923\/ajdd.2013.72.83","article-title":"Evaluation of antibacterial and antioxidant activities of different methanol extract of Rumex vesicarius L. (Polygonaceae)","volume":"3","author":"Tukappa","year":"2013","journal-title":"Am. J. Drug Discov. Dev."},{"key":"ref_190","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1111\/j.1541-4337.2011.00169.x","article-title":"Flower Extracts and Their Essential Oils as Potential Antimicrobial Agents for Food Uses and Pharmaceutical Applications","volume":"11","author":"Voon","year":"2012","journal-title":"Compr. Rev. Food Sci. Food Saf."},{"key":"ref_191","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.fbp.2012.12.006","article-title":"Extraction optimization of oleanolic and ursolic acids from pomegranate (Punica granatum L.) flowers","volume":"92","author":"Fu","year":"2014","journal-title":"Food Bioprod. Process."},{"key":"ref_192","doi-asserted-by":"crossref","first-page":"109216","DOI":"10.1016\/j.foodres.2020.109216","article-title":"Edible flowers as a new source of natural antioxidants for oxidative protection of cold-pressed oils rich in omega-3 fatty acids","volume":"134","author":"Sobiechowska","year":"2020","journal-title":"Food Res. Int."},{"key":"ref_193","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1002\/ptr.2023","article-title":"Moringa oleifera: A Food Plant with Multiple Medicinal Uses","volume":"21","author":"Anwar","year":"2007","journal-title":"Phyther. Res."},{"key":"ref_194","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.nfs.2021.06.001","article-title":"Phytochemical and nutritional compositions and antioxidants properties of wild edible flowers as sources of new tea formulations","volume":"24","author":"Suksathan","year":"2021","journal-title":"NFS J."},{"key":"ref_195","doi-asserted-by":"crossref","unstructured":"Li, R., Ru, Y., Wang, Z., He, X., Kong, K.W., Zheng, T., and Zhang, X. (2021). Phytochemical composition, antioxidant activity, and enzyme inhibitory activities (\u03b1-glucosidase, xanthine oxidase, and acetylcholinesterase) of Musella lasiocarpa. Molecules, 26.","DOI":"10.3390\/molecules26154472"},{"key":"ref_196","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/09735070.2017.1311692","article-title":"Evaluation of anti-arthritic, HRBC membrane stabilization and antioxidant properties of the edible Phlogacanthus thyrsiformis (Hardow) Mabb flower extracts and their correlation studies","volume":"11","author":"Das","year":"2017","journal-title":"Stud. Ethno-Med."},{"key":"ref_197","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.phytochem.2017.11.008","article-title":"Phytochemical variation among the traditional Chinese medicine Mu Dan Pi from Paeonia suffruticosa (tree peony)","volume":"146","author":"Li","year":"2018","journal-title":"Phytochemistry"},{"key":"ref_198","first-page":"1457","article-title":"Calotroposid A: A glycosides terpenoids from Calotropis gigantea induces apoptosis of colon cancer WiDr cells through cell cycle arrest G2\/M and caspase 8 expression","volume":"19","author":"Mutiah","year":"2018","journal-title":"Asian Pacific J. Cancer Prev."},{"key":"ref_199","doi-asserted-by":"crossref","first-page":"100078","DOI":"10.1016\/j.fufo.2021.100078","article-title":"A review on nutritional, bioactive, toxicological properties and preservation of edible flowers","volume":"4","author":"Purohit","year":"2021","journal-title":"Futur. Foods"},{"key":"ref_200","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/s11130-007-0053-9","article-title":"Content of nutrient and antinutrient in edible flowers of wild plants in Mexico","volume":"62","author":"Sotelo","year":"2007","journal-title":"Plant. Foods Hum. Nutr."},{"key":"ref_201","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1002\/pca.2806","article-title":"Composition analysis of carotenoids and phenolic compounds and antioxidant activity from hibiscus calyces (Hibiscus sabdariffa L.) by HPLC-DAD-MS\/MS","volume":"30","author":"Piovesana","year":"2019","journal-title":"Phytochem. Anal."},{"key":"ref_202","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1016\/j.tifs.2019.07.017","article-title":"Edible flowers. Benefits and risks pertaining to their consumption","volume":"91","author":"Matyjaszczyk","year":"2019","journal-title":"Trends Food Sci. Technol."},{"key":"ref_203","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.fct.2018.12.055","article-title":"Comment on article \u201cAre wild and cultivated flowers served in restaurants or sold by local producers in Denmark safe for the consumer?\u201d Food and Chemical Toxicology 120 (2018) 129\u2013142, doi:10.1016\/j.fct.2018.07.007","volume":"125","year":"2019","journal-title":"Food Chem. Toxicol."},{"key":"ref_204","first-page":"417","article-title":"Most commonly plant exposures and intoxications from outdoor toxic plants","volume":"2","author":"Colombo","year":"2010","journal-title":"J. Pharm. Sci. Res."}],"container-title":["Molecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1420-3049\/26\/22\/6940\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T07:31:45Z","timestamp":1760167905000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1420-3049\/26\/22\/6940"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,17]]},"references-count":204,"journal-issue":{"issue":"22","published-online":{"date-parts":[[2021,11]]}},"alternative-id":["molecules26226940"],"URL":"https:\/\/doi.org\/10.3390\/molecules26226940","relation":{},"ISSN":["1420-3049"],"issn-type":[{"value":"1420-3049","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,17]]}}}