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In this study, Salicornia ramosissima and Sarcocornia perennis alpini were evaluated for nutrients, bioactive compounds, antioxidant capacity, and contaminants. Both were shown to be nutritionally relevant, exhibiting notable levels of crude fibre and ash, i.e., 11.26\u201315.34 and 39.46\u201340.41% dry weight (dw), respectively, and the major minerals were Na, K, and Mg. Total phenolics thereof were 67.05 and 38.20 mg of gallic acid equivalents\/g extract dw, respectively, mainly p-coumaric acid and quercetin. Both species displayed antioxidant capacity, but S. ramossima was prominent in both the DPPH and \u00df-carotene bleaching assays. Aflatoxin B1 was detected in S. ramosissima, at 5.21 \u00b5g\/Kg dw, which may pose a health threat. The Cd and Pb levels in both were low, but the 0.01 mg\/Kg Hg in S. perennis alpini met the maximum legal limit established for marine species including algae. Both species exhibit high potential for use in the agro-food, cosmetics, and pharmaceutical sectors, but specific regulations and careful cultivation strategies need to be implemented, in order to minimise contamination risks by mycotoxins and heavy metals.<\/jats:p>","DOI":"10.3390\/molecules28062726","type":"journal-article","created":{"date-parts":[[2023,3,20]],"date-time":"2023-03-20T03:09:37Z","timestamp":1679281777000},"page":"2726","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Towards the Sustainable Exploitation of Salt-Tolerant Plants: Nutritional Characterisation, Phenolics Composition, and Potential Contaminants Analysis of Salicornia ramosissima and Sarcocornia perennis alpini"],"prefix":"10.3390","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0683-5685","authenticated-orcid":false,"given":"Maria","family":"Lopes","sequence":"first","affiliation":[{"name":"University of Coimbra, Faculty of Pharmacy, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal"},{"name":"Associated Laboratory for Green Chemistry (LAQV) of the Network of Chemistry and Technology (REQUIMTE), R. D. Manuel II, Apartado 55142, 4051-401 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0226-921X","authenticated-orcid":false,"given":"Ana Sanches","family":"Silva","sequence":"additional","affiliation":[{"name":"University of Coimbra, Faculty of Pharmacy, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal"},{"name":"National Institute for Agricultural and Veterinary Research (INIAV), I.P., Rua dos Lagidos, Lugar da Madalena, 4485-655 Vila do Conde, Portugal"},{"name":"Centre for Study in Animal Science (CECA), ICETA, University of Porto, 4051-501 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0623-4409","authenticated-orcid":false,"given":"Raquel","family":"S\u00e9ndon","sequence":"additional","affiliation":[{"name":"Analytical Chemistry, Nutrition and Food Science Department, Pharmacy Faculty, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7158-6980","authenticated-orcid":false,"given":"Letricia","family":"Barbosa-Pereira","sequence":"additional","affiliation":[{"name":"Analytical Chemistry, Nutrition and Food Science Department, Pharmacy Faculty, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5937-1127","authenticated-orcid":false,"given":"Carlos","family":"Cavaleiro","sequence":"additional","affiliation":[{"name":"University of Coimbra, Faculty of Pharmacy, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal"},{"name":"Chemical Process Engineering and Forest Products Research Centre, University of Coimbra, Rua S\u00edlvio Lima, Polo II, 3030-790 Coimbra, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6043-819X","authenticated-orcid":false,"given":"Fernando","family":"Ramos","sequence":"additional","affiliation":[{"name":"University of Coimbra, Faculty of Pharmacy, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal"},{"name":"Associated Laboratory for Green Chemistry (LAQV) of the Network of Chemistry and Technology (REQUIMTE), R. D. Manuel II, Apartado 55142, 4051-401 Porto, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2023,3,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"82","DOI":"10.11646\/phytotaxa.272.1.5","article-title":"Counting counts: Revised estimates of numbers of accepted species of flowering plants, seed plants, vascular plants and land plants with a review of other recent estimates","volume":"272","author":"Lughadha","year":"2016","journal-title":"Phytotaxa"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"S8","DOI":"10.1038\/544S8a","article-title":"Agrobiodiversity: The living library","volume":"544","author":"Gruber","year":"2017","journal-title":"Nature"},{"key":"ref_3","unstructured":"FAO, IFAD, UNICEF, WFP, and WHO (2021). 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